BR0214277A - Solvatos de paclitaxel - Google Patents

Solvatos de paclitaxel

Info

Publication number
BR0214277A
BR0214277A BR0214277-5A BR0214277A BR0214277A BR 0214277 A BR0214277 A BR 0214277A BR 0214277 A BR0214277 A BR 0214277A BR 0214277 A BR0214277 A BR 0214277A
Authority
BR
Brazil
Prior art keywords
solvates
paclitaxel
paclitaxel solvates
aprotic
precipitated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
BR0214277-5A
Other languages
English (en)
Inventor
Daniel A Benigni
Jack Z Gougoutas
John D Dimarco
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol-Myers Co
Bristol-Myers Squibb Co
Original Assignee
Bristol-Myers Co
Bristol-Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Co, Bristol-Myers Squibb Co filed Critical Bristol-Myers Co
Publication of BR0214277A publication Critical patent/BR0214277A/pt
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"SOLVATOS DE PACLITAXEL". Solvatos cristalinos biologicamente ativos de paclitaxel são precipitados usando solventes polares, apróticos e orgânicos. Uma composição farmacêutica é também descrita, bem como a preparação dos novos solvatos e seus usos como agentes anti-tumor.
BR0214277-5A 2001-11-30 2002-11-25 Solvatos de paclitaxel Expired - Fee Related BR0214277A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33489601P 2001-11-30 2001-11-30
PCT/US2002/037901 WO2003047508A2 (en) 2001-11-30 2002-11-25 Paclitaxel solvates

Publications (1)

Publication Number Publication Date
BR0214277A true BR0214277A (pt) 2004-09-21

Family

ID=23309330

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0214277-5A Expired - Fee Related BR0214277A (pt) 2001-11-30 2002-11-25 Solvatos de paclitaxel

Country Status (13)

Country Link
US (1) US6858644B2 (pt)
EP (1) EP1451168A4 (pt)
JP (1) JP4451660B2 (pt)
KR (1) KR20050044621A (pt)
CN (1) CN1596250A (pt)
AU (1) AU2002365883A1 (pt)
BR (1) BR0214277A (pt)
HU (1) HUP0600533A2 (pt)
IL (1) IL161372A0 (pt)
MX (1) MXPA04005038A (pt)
PL (1) PL368945A1 (pt)
TW (1) TW200300671A (pt)
WO (1) WO2003047508A2 (pt)

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WO2013162922A1 (en) * 2012-04-25 2013-10-31 Genta Incorporated Taxane compounds, compositions and methods
US11167063B2 (en) 2013-03-14 2021-11-09 W. L. Gore & Associates, Inc. Porous composites with high-aspect ratio crystals
US9872940B2 (en) 2013-04-01 2018-01-23 Terumo Kabushiki Kaisha Drug coating layer
CN103833693B (zh) * 2014-03-04 2016-02-24 悦康药业集团有限公司 一种紫杉醇化合物及含该紫杉醇化合物的药物组合物
CN106163603B (zh) 2014-04-01 2019-11-15 泰尔茂株式会社 用于球囊涂敷的定位方法
WO2015151877A1 (ja) 2014-04-01 2015-10-08 テルモ株式会社 バルーンコーティング方法、コート層制御方法およびバルーンコーティング装置
JP6504571B2 (ja) 2014-04-01 2019-04-24 テルモ株式会社 バルーンコーティング方法
EP3106196B1 (en) 2014-04-01 2019-09-18 Terumo Kabushiki Kaisha Positioning method for balloon coating
US10149925B2 (en) 2014-05-16 2018-12-11 Terumo Kabushiki Kaisha Method of reducing the risk of embolization of peripheral blood vessels
US10188771B2 (en) 2014-05-16 2019-01-29 Terumo Kabushiki Kaisha Method of treating peripheral artery diseases in lower limbs
US10143779B2 (en) 2014-05-16 2018-12-04 Terumo Kabushiki Kaisha Method of inhibiting thickening of vascular intima
US9901719B2 (en) 2015-04-23 2018-02-27 Terumo Kabushiki Kaisha Balloon coating method, balloon rotating method and balloon coating apparatus
US10561766B2 (en) 2015-09-15 2020-02-18 W. L. Gore & Associates, Inc. Drug composition and coating
US11369778B2 (en) 2016-03-23 2022-06-28 Terumo Kabushiki Kaisha Balloon catheter and manufacturing method thereof, and treatment method

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Also Published As

Publication number Publication date
KR20050044621A (ko) 2005-05-12
JP2005511646A (ja) 2005-04-28
EP1451168A2 (en) 2004-09-01
IL161372A0 (en) 2004-09-27
MXPA04005038A (es) 2004-08-11
WO2003047508A2 (en) 2003-06-12
US6858644B2 (en) 2005-02-22
AU2002365883A1 (en) 2003-06-17
TW200300671A (en) 2003-06-16
PL368945A1 (en) 2005-04-04
US20030144344A1 (en) 2003-07-31
JP4451660B2 (ja) 2010-04-14
HUP0600533A2 (en) 2006-11-28
WO2003047508A3 (en) 2003-10-30
CN1596250A (zh) 2005-03-16
EP1451168A4 (en) 2005-08-24

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2064 DE 27/07/2010.