BR0212333A - Liberação controlada de suspensões de peptìdeos microcristalino - Google Patents

Liberação controlada de suspensões de peptìdeos microcristalino

Info

Publication number
BR0212333A
BR0212333A BR0212333-9A BR0212333A BR0212333A BR 0212333 A BR0212333 A BR 0212333A BR 0212333 A BR0212333 A BR 0212333A BR 0212333 A BR0212333 A BR 0212333A
Authority
BR
Brazil
Prior art keywords
peptide
controlled release
formation
gel
microcrystalline
Prior art date
Application number
BR0212333-9A
Other languages
English (en)
Portuguese (pt)
Inventor
Romano Deghenghi
Francois Boutignon
Original Assignee
Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris Gmbh filed Critical Zentaris Gmbh
Publication of BR0212333A publication Critical patent/BR0212333A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/31Somatostatins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
BR0212333-9A 2001-09-06 2002-08-27 Liberação controlada de suspensões de peptìdeos microcristalino BR0212333A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31761601P 2001-09-06 2001-09-06
PCT/EP2002/009537 WO2003022243A2 (en) 2001-09-06 2002-08-27 Sustained release of microcrystalline peptide suspensions

Publications (1)

Publication Number Publication Date
BR0212333A true BR0212333A (pt) 2004-09-21

Family

ID=23234486

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0212333-9A BR0212333A (pt) 2001-09-06 2002-08-27 Liberação controlada de suspensões de peptìdeos microcristalino

Country Status (26)

Country Link
US (5) US7098305B2 (enExample)
EP (2) EP2198888B1 (enExample)
JP (3) JP2005504787A (enExample)
KR (2) KR20070107161A (enExample)
CN (1) CN100386116C (enExample)
AR (1) AR042592A1 (enExample)
AT (1) ATE463258T1 (enExample)
AU (1) AU2002337025B2 (enExample)
BR (1) BR0212333A (enExample)
CA (1) CA2459309C (enExample)
CY (1) CY1118642T1 (enExample)
DE (1) DE60235896D1 (enExample)
DK (1) DK2198888T3 (enExample)
ES (2) ES2362505T3 (enExample)
HU (1) HUP0402099A2 (enExample)
IL (1) IL160443A0 (enExample)
MX (1) MXPA04002185A (enExample)
NO (1) NO20040938L (enExample)
NZ (1) NZ531734A (enExample)
PL (1) PL368056A1 (enExample)
PT (1) PT2198888T (enExample)
RU (1) RU2311195C2 (enExample)
TW (1) TWI249409B (enExample)
UA (1) UA79435C2 (enExample)
WO (1) WO2003022243A2 (enExample)
ZA (1) ZA200401390B (enExample)

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Also Published As

Publication number Publication date
US20060229238A1 (en) 2006-10-12
NO20040938L (no) 2004-06-04
NZ531734A (en) 2006-02-24
PL368056A1 (en) 2005-03-21
MXPA04002185A (es) 2004-07-23
RU2311195C2 (ru) 2007-11-27
CN1551785A (zh) 2004-12-01
JP5757686B2 (ja) 2015-07-29
UA79435C2 (en) 2007-06-25
HK1062148A1 (en) 2004-10-21
JP2010095533A (ja) 2010-04-30
JP2005504787A (ja) 2005-02-17
CA2459309A1 (en) 2003-03-20
KR100818904B1 (ko) 2008-04-04
TWI249409B (en) 2006-02-21
US20100239683A1 (en) 2010-09-23
US20110312889A1 (en) 2011-12-22
CA2459309C (en) 2012-04-03
KR20070107161A (ko) 2007-11-06
NO20040938D0 (no) 2004-03-04
US20030044463A1 (en) 2003-03-06
HUP0402099A2 (hu) 2005-02-28
JP2013177449A (ja) 2013-09-09
IL160443A0 (en) 2004-07-25
DE60235896D1 (de) 2010-05-20
CY1118642T1 (el) 2017-07-12
US7098305B2 (en) 2006-08-29
ES2362505T3 (es) 2011-07-06
AU2002337025B2 (en) 2006-12-07
CN100386116C (zh) 2008-05-07
KR20040037077A (ko) 2004-05-04
WO2003022243A2 (en) 2003-03-20
DK2198888T3 (en) 2017-02-13
RU2004110615A (ru) 2005-05-10
WO2003022243A3 (en) 2003-10-30
US8415300B2 (en) 2013-04-09
EP2198888B1 (en) 2016-11-02
EP1423150A2 (en) 2004-06-02
ES2618777T3 (es) 2017-06-22
EP2198888A3 (en) 2011-08-31
ATE463258T1 (de) 2010-04-15
AR042592A1 (es) 2005-06-29
ZA200401390B (en) 2004-08-27
EP1423150B1 (en) 2010-04-07
PT2198888T (pt) 2017-02-10
EP2198888A2 (en) 2010-06-23
US20060228385A1 (en) 2006-10-12

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