BR0209956A - Uso da 4- (2-fluorofenil)-6-metil-2- (1-piperazinil)tieno [2,3-d]pirimidina para o tratamento da dor - Google Patents

Uso da 4- (2-fluorofenil)-6-metil-2- (1-piperazinil)tieno [2,3-d]pirimidina para o tratamento da dor

Info

Publication number
BR0209956A
BR0209956A BR0209956-0A BR0209956A BR0209956A BR 0209956 A BR0209956 A BR 0209956A BR 0209956 A BR0209956 A BR 0209956A BR 0209956 A BR0209956 A BR 0209956A
Authority
BR
Brazil
Prior art keywords
thieno
piperazinyl
fluorophenyl
pyrimidine
methyl
Prior art date
Application number
BR0209956-0A
Other languages
English (en)
Inventor
Hazel Judith Bardsley
William Gristwood
David Cavalla
Original Assignee
Arachnova Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arachnova Therapeutics Ltd filed Critical Arachnova Therapeutics Ltd
Publication of BR0209956A publication Critical patent/BR0209956A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

"USO DA 4-(2-FLUOROFENIL)-6-METIL-2-(1-PIPERAZINIL) TIENO [2,3-D] PIRIMIDINA PARA O TRATAMENTO DA DOR". A 4-(2-fluorofenil) -6-metil-2- (1-piperazinil) tieno [2,3-D]pirimidina, ou um seu sal, é útil para o tratamento da dor.
BR0209956-0A 2001-05-22 2002-05-21 Uso da 4- (2-fluorofenil)-6-metil-2- (1-piperazinil)tieno [2,3-d]pirimidina para o tratamento da dor BR0209956A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0112494.0A GB0112494D0 (en) 2001-05-22 2001-05-22 New therapeutic use
PCT/GB2002/002388 WO2002094249A1 (en) 2001-05-22 2002-05-21 Use of 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)thieno[2,3-d]pyrimidine for the treatment of pain

Publications (1)

Publication Number Publication Date
BR0209956A true BR0209956A (pt) 2004-04-20

Family

ID=9915109

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0209956-0A BR0209956A (pt) 2001-05-22 2002-05-21 Uso da 4- (2-fluorofenil)-6-metil-2- (1-piperazinil)tieno [2,3-d]pirimidina para o tratamento da dor

Country Status (15)

Country Link
EP (1) EP1390022B1 (pt)
JP (1) JP3749519B2 (pt)
KR (1) KR20040012808A (pt)
CN (1) CN1230176C (pt)
AT (1) ATE359769T1 (pt)
AU (1) AU2002307872B2 (pt)
BR (1) BR0209956A (pt)
CA (1) CA2447465A1 (pt)
DE (1) DE60219616T2 (pt)
DK (1) DK1390022T3 (pt)
ES (1) ES2283598T3 (pt)
GB (1) GB0112494D0 (pt)
PT (1) PT1390022E (pt)
SI (1) SI1390022T1 (pt)
WO (1) WO2002094249A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0216027D0 (en) 2002-07-10 2002-08-21 Arachnova Therapeutics Ltd New therapeutic use
US20040087642A1 (en) * 2002-10-24 2004-05-06 Zeldis Jerome B. Methods of using and compositions comprising a JNK inhibitor for the treatment, prevention, management and/or modification of pain
KR20050094843A (ko) 2003-01-13 2005-09-28 다이노젠 파마세우티컬스, 인코포레이티드 욕지기, 구토, 구역질 또는 이들의 조합을 치료하는 방법
AU2004204825B2 (en) * 2003-01-13 2007-07-19 Dynogen Pharmaceuticals, Inc. Method of treating functional bowel disorders
EP1795196A3 (en) * 2003-04-04 2008-02-06 Dynogen Pharmaceuticals, Inc. Method of treating lower urinary tract disorders
ATE365554T1 (de) 2003-04-04 2007-07-15 Dynogen Pharmaceuticals Inc Methode zur behandlung von erkrankungen der unteren harnwege

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60146891A (ja) * 1984-01-05 1985-08-02 Mitsubishi Chem Ind Ltd 〔２，３−ｄ〕チエノピリミジン誘導体およびその塩

Also Published As

Publication number Publication date
PT1390022E (pt) 2007-05-31
JP2004531557A (ja) 2004-10-14
DE60219616T2 (de) 2008-01-31
KR20040012808A (ko) 2004-02-11
ES2283598T3 (es) 2007-11-01
CA2447465A1 (en) 2002-11-28
GB0112494D0 (en) 2001-07-11
JP3749519B2 (ja) 2006-03-01
AU2002307872B2 (en) 2004-10-07
SI1390022T1 (sl) 2007-08-31
EP1390022B1 (en) 2007-04-18
WO2002094249A1 (en) 2002-11-28
CN1511029A (zh) 2004-07-07
EP1390022A1 (en) 2004-02-25
ATE359769T1 (de) 2007-05-15
DE60219616D1 (de) 2007-05-31
CN1230176C (zh) 2005-12-07
DK1390022T3 (da) 2007-08-13

Similar Documents

Publication Publication Date Title
EA200500721A1 (ru) Пиримидины, ингибирующие chk, pdk и акт, их получение и применение в качестве лекарственных средств
ECSP034774A (es) Pirazolopirimmidinas como agentes terapeuticos
PT1242425E (pt) Compostos de n-(5,7-dimetoxi¬1,2,4|triazolo1,5-a|pirimidin-2-il) arilsulfonamida e sua utilizacao como herbicidas
MA26881A1 (fr) 5-alkyl-pyrido [2,3-d]pyrimidines inhibitrices de tyrosine-kinases.
NO20031852D0 (no) Pyrimidin-2,4,6-trion metalloproteinase inhibitorer
EE200300239A (et) Rosuvastatiini (ZD4522) kasutamine heterosügootseperekondliku hüperkolesteroleemia raviks
IS2399B (is) Aðferðir til að framleiða 2-(N-metýl-N-metansúlfónýlamínó)pýrimidín, hýdroxýpýrimidín, halógenpýrimidín eða lífrænar súlfónýloxýpýrimidín afleiður ogefnasambönd sem fást með þeim
RS50091B (sr) Upotreba retigabina u lečenju neuropatskog bola
MY134568A (en) Cb2 receptor agonists
JO2311B1 (en) Alkyl inhibitors Ariel phosphodiesterase-4
DE602004005814D1 (de) Verfahren zur behandlung von übelkeit, erbrechen, würgereiz oder jede kombination daraus
EE200300475A (et) Türosiini kinaasi inhibiitorid, neid sisaldavad ravimkoostised ja nimetatud ühendid kasutamiseks haiguste ravis
BRPI0516242A (pt) compostos tieno-pirimidina tendo atividade fungicida
SV2003001173A (es) 1-alquil o 1-cicloalquil-triazolo [4,3-a] quinazolin-5- onas como inhibidoras de fosfodiesterasa
DE60216233D1 (en) Carbolinderivate
SE9802208D0 (sv) Novel compounds
YU102503A (sh) Kondenzovani pirimidinski dhfr inhibitori kao antibakterijska sredstva
BR0114379A (pt) Derivados de c-ciclohexilmetilamina substituìdos
DE60112960D1 (de) Kondensierte pyridoindolderivate
BR0307369A (pt) Uso de 4-(2-fluoro-fenil)-6-metil-2-(1-piperazinil)-tieno (2,3-d)-pirimidina para o tratamento de incontinência urinária
BR0209956A (pt) Uso da 4- (2-fluorofenil)-6-metil-2- (1-piperazinil)tieno [2,3-d]pirimidina para o tratamento da dor
MXPA04001419A (es) Isoxazolopiridinonas y su uso en el tratamiento de enfermedad de parkinson.
SE9802209D0 (sv) Novel compounds
ATE325115T1 (de) Pyrimidinderivate als selektive cox-2-inhibitoren
BR0312511A (pt) 4- (2-fluorofenil)-6-metil-2- (1-piperazinil) tieno [2,3-d] pirimidina no tratamento de distúrbio funcional dos intestinos

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A E 9A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2108 DE 31/05/2011.