BR0209956A - Use of 4- (2-fluorophenyl) -6-methyl-2- (1-piperazinyl) thieno [2,3-d] pyrimidine for pain management - Google Patents

Use of 4- (2-fluorophenyl) -6-methyl-2- (1-piperazinyl) thieno [2,3-d] pyrimidine for pain management

Info

Publication number
BR0209956A
BR0209956A BR0209956-0A BR0209956A BR0209956A BR 0209956 A BR0209956 A BR 0209956A BR 0209956 A BR0209956 A BR 0209956A BR 0209956 A BR0209956 A BR 0209956A
Authority
BR
Brazil
Prior art keywords
thieno
piperazinyl
fluorophenyl
pyrimidine
methyl
Prior art date
Application number
BR0209956-0A
Other languages
Portuguese (pt)
Inventor
Hazel Judith Bardsley
William Gristwood
David Cavalla
Original Assignee
Arachnova Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arachnova Therapeutics Ltd filed Critical Arachnova Therapeutics Ltd
Publication of BR0209956A publication Critical patent/BR0209956A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

4-(2-Fluorophenyl)-6-methyl-2-(1-piperazinyl)thieno[2,3-D]pyrimidine or a salt thereof is useful for the treatment of pain.
BR0209956-0A 2001-05-22 2002-05-21 Use of 4- (2-fluorophenyl) -6-methyl-2- (1-piperazinyl) thieno [2,3-d] pyrimidine for pain management BR0209956A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0112494.0A GB0112494D0 (en) 2001-05-22 2001-05-22 New therapeutic use
PCT/GB2002/002388 WO2002094249A1 (en) 2001-05-22 2002-05-21 Use of 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)thieno[2,3-d]pyrimidine for the treatment of pain

Publications (1)

Publication Number Publication Date
BR0209956A true BR0209956A (en) 2004-04-20

Family

ID=9915109

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0209956-0A BR0209956A (en) 2001-05-22 2002-05-21 Use of 4- (2-fluorophenyl) -6-methyl-2- (1-piperazinyl) thieno [2,3-d] pyrimidine for pain management

Country Status (15)

Country Link
EP (1) EP1390022B1 (en)
JP (1) JP3749519B2 (en)
KR (1) KR20040012808A (en)
CN (1) CN1230176C (en)
AT (1) ATE359769T1 (en)
AU (1) AU2002307872B2 (en)
BR (1) BR0209956A (en)
CA (1) CA2447465A1 (en)
DE (1) DE60219616T2 (en)
DK (1) DK1390022T3 (en)
ES (1) ES2283598T3 (en)
GB (1) GB0112494D0 (en)
PT (1) PT1390022E (en)
SI (1) SI1390022T1 (en)
WO (1) WO2002094249A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0216027D0 (en) 2002-07-10 2002-08-21 Arachnova Therapeutics Ltd New therapeutic use
US20040087642A1 (en) * 2002-10-24 2004-05-06 Zeldis Jerome B. Methods of using and compositions comprising a JNK inhibitor for the treatment, prevention, management and/or modification of pain
JP2006516977A (en) 2003-01-13 2006-07-13 ダイノゲン ファーマシューティカルズ，インコーポレイテッド How to treat nausea, vomiting, retching, or any combination thereof
NZ541008A (en) * 2003-01-13 2007-09-28 Dynogen Pharmaceuticals Inc Method of treating functional bowel disorders
DE602004007225T2 (en) 2003-04-04 2008-03-06 Dynogen Pharmaceuticals Inc., Waltham METHOD FOR THE TREATMENT OF LOWER HARN PATTERNS
EP1795196A3 (en) * 2003-04-04 2008-02-06 Dynogen Pharmaceuticals, Inc. Method of treating lower urinary tract disorders

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60146891A (en) * 1984-01-05 1985-08-02 Mitsubishi Chem Ind Ltd (2,3-d)thienopyrimidine derivative and its salt

Also Published As

Publication number Publication date
DK1390022T3 (en) 2007-08-13
EP1390022A1 (en) 2004-02-25
ES2283598T3 (en) 2007-11-01
EP1390022B1 (en) 2007-04-18
DE60219616T2 (en) 2008-01-31
AU2002307872B2 (en) 2004-10-07
PT1390022E (en) 2007-05-31
CN1511029A (en) 2004-07-07
DE60219616D1 (en) 2007-05-31
JP2004531557A (en) 2004-10-14
SI1390022T1 (en) 2007-08-31
GB0112494D0 (en) 2001-07-11
ATE359769T1 (en) 2007-05-15
CA2447465A1 (en) 2002-11-28
CN1230176C (en) 2005-12-07
KR20040012808A (en) 2004-02-11
WO2002094249A1 (en) 2002-11-28
JP3749519B2 (en) 2006-03-01

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A E 9A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2108 DE 31/05/2011.