BR0209163A - Composto e processos para preparar um composto - Google Patents

Composto e processos para preparar um composto

Info

Publication number
BR0209163A
BR0209163A BR0209163-1A BR0209163A BR0209163A BR 0209163 A BR0209163 A BR 0209163A BR 0209163 A BR0209163 A BR 0209163A BR 0209163 A BR0209163 A BR 0209163A
Authority
BR
Brazil
Prior art keywords
compound
processes
preparing
intermediates
production
Prior art date
Application number
BR0209163-1A
Other languages
English (en)
Inventor
Michael R Reeder
Original Assignee
Elan Pharm Inc
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Pharm Inc, Upjohn Co filed Critical Elan Pharm Inc
Publication of BR0209163A publication Critical patent/BR0209163A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D301/00—Preparation of oxiranes
    • C07D301/02—Synthesis of the oxirane ring
    • C07D301/24—Synthesis of the oxirane ring by splitting off HAL—Y from compounds containing the radical HAL—C—C—OY
    • C07D301/26—Y being hydrogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"COMPOSTO E PROCESSOS PARA PREPARAR UM COMPOSTO". São descritos intermediários e processos para preparar epóxidos de fórmula: onde R e PROT são definidos aqui. Estes epóxidos são úteis como intermediários na produção de compostos biologicamente ativos, isto é, na produção de agentes farmacêuticos.
BR0209163-1A 2001-04-23 2002-04-23 Composto e processos para preparar um composto BR0209163A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28577201P 2001-04-23 2001-04-23
PCT/US2002/012591 WO2002085877A2 (en) 2001-04-23 2002-04-23 Processes and intermediates for preparing benzyl substituted epoxides

Publications (1)

Publication Number Publication Date
BR0209163A true BR0209163A (pt) 2004-08-24

Family

ID=23095626

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0209163-1A BR0209163A (pt) 2001-04-23 2002-04-23 Composto e processos para preparar um composto

Country Status (23)

Country Link
US (3) US6849750B2 (pt)
EP (1) EP1381597B1 (pt)
JP (1) JP2004529152A (pt)
KR (1) KR20040047750A (pt)
CN (1) CN1612871A (pt)
AP (1) AP2003002897A0 (pt)
AR (1) AR035960A1 (pt)
AT (1) ATE401299T1 (pt)
BR (1) BR0209163A (pt)
CA (1) CA2445163A1 (pt)
CO (1) CO5650163A2 (pt)
DE (1) DE60227652D1 (pt)
EA (1) EA007535B1 (pt)
ES (1) ES2309170T3 (pt)
IL (2) IL158585A0 (pt)
MX (1) MXPA03009723A (pt)
NO (1) NO20034738L (pt)
NZ (1) NZ529169A (pt)
OA (1) OA12597A (pt)
PE (1) PE20021068A1 (pt)
PL (1) PL365058A1 (pt)
WO (1) WO2002085877A2 (pt)
ZA (1) ZA200308261B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0228410D0 (en) * 2002-12-05 2003-01-08 Glaxo Group Ltd Novel Compounds
WO2005087751A2 (en) 2004-03-09 2005-09-22 Elan Pharmaceuticals, Inc. Substituted hydroxyethylamine aspartyl protease inhibitors
US7385085B2 (en) 2004-07-09 2008-06-10 Elan Pharmaceuticals, Inc. Oxime derivative substituted hydroxyethylamine aspartyl protease inhibitors
WO2007047305A1 (en) 2005-10-12 2007-04-26 Elan Pharmaceuticals, Inc. Methods of treating amyloidosis using cyclopropyl derivative aspartyl protease inhibitors
WO2019168874A1 (en) 2018-02-27 2019-09-06 The Research Foundation For The State University Of New York Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2788044B2 (ja) 1989-02-06 1998-08-20 サントリー株式会社 マレイミド誘導体およびそれを有効成分として含有する農園芸用殺菌剤
US5482947A (en) * 1990-11-19 1996-01-09 Talley; John J. Retroviral protease inhibitors
US5583238A (en) 1990-11-19 1996-12-10 G. D. Searle & Co. Method for making intermediates useful in synthesis of retroviral protease inhibitors
US5559256A (en) * 1992-07-20 1996-09-24 E. R. Squibb & Sons, Inc. Aminediol protease inhibitors
AU669223B2 (en) 1992-08-25 1996-05-30 G.D. Searle & Co. Sulfonylalkanoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors
US5481011A (en) * 1994-12-13 1996-01-02 Bristol-Myers Squibb Company Process for preparing N-protected amino acid α-halomethyl ketones and alcohols from N-protected amino acid esters
US5985911A (en) * 1997-01-07 1999-11-16 Abbott Laboratories C-terminal ketone inhibitors of matrix metalloproteinases and TNFα secretion
JP2001510474A (ja) * 1997-02-04 2001-07-31 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア カテプシンｄのナノモルの非ペプチド阻害剤
CA2273643A1 (en) 1998-06-09 1999-12-09 F. Hoffmann-La Roche Ag Stereoselective reduction of carbonyl compounds
CA2401749A1 (en) 2000-03-23 2001-09-27 Elan Pharmaceuticals, Inc. Compounds and methods to treat alzheimer's disease
ATE314343T1 (de) 2000-06-30 2006-01-15 Elan Pharm Inc Verbindungen zur behandlung der alzheimerischen krankheit
PE20020276A1 (es) 2000-06-30 2002-04-06 Elan Pharm Inc COMPUESTOS DE AMINA SUSTITUIDA COMO INHIBIDORES DE ß-SECRETASA PARA EL TRATAMIENTO DE ALZHEIMER
US20030096864A1 (en) 2000-06-30 2003-05-22 Fang Lawrence Y. Compounds to treat alzheimer's disease
US6846813B2 (en) 2000-06-30 2005-01-25 Pharmacia & Upjohn Company Compounds to treat alzheimer's disease
BR0214736A (pt) 2001-12-06 2004-11-23 Elan Pharm Inc Composto e seus sais farmaceuticamente aceitáveis, composição farmacêutica e método de tratar seres humanos ou animais que sofrem de doenças ou condições

Also Published As

Publication number Publication date
OA12597A (en) 2006-06-08
US7638646B2 (en) 2009-12-29
MXPA03009723A (es) 2004-03-16
IL158585A0 (en) 2004-05-12
NO20034738D0 (no) 2003-10-23
US20100099898A1 (en) 2010-04-22
EP1381597A2 (en) 2004-01-21
KR20040047750A (ko) 2004-06-05
EA200301133A1 (ru) 2004-04-29
NO20034738L (no) 2003-12-04
EA007535B1 (ru) 2006-10-27
ES2309170T3 (es) 2008-12-16
AR035960A1 (es) 2004-07-28
EP1381597B1 (en) 2008-07-16
NZ529169A (en) 2005-06-24
US20030004360A1 (en) 2003-01-02
IL158585A (en) 2009-06-15
US20050130936A1 (en) 2005-06-16
PL365058A1 (en) 2004-12-27
JP2004529152A (ja) 2004-09-24
WO2002085877A2 (en) 2002-10-31
WO2002085877A3 (en) 2003-03-06
CO5650163A2 (es) 2006-06-30
AP2003002897A0 (en) 2003-12-31
CN1612871A (zh) 2005-05-04
CA2445163A1 (en) 2002-10-31
DE60227652D1 (de) 2008-08-28
PE20021068A1 (es) 2002-12-11
US6849750B2 (en) 2005-02-01
ATE401299T1 (de) 2008-08-15
ZA200308261B (en) 2004-05-24

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DA INT.CL: C07D 301/26, C07D 303/36

Ipc: C07D 301/26 (2011.01), C07D 303/36 (2011.01), A61P

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A(S) 8A E 9A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2103 DE 26/04/2011.