BR0206955A - Ligantes de receptores de canabinóides - Google Patents

Ligantes de receptores de canabinóides

Info

Publication number
BR0206955A
BR0206955A BR0206955-5A BR0206955A BR0206955A BR 0206955 A BR0206955 A BR 0206955A BR 0206955 A BR0206955 A BR 0206955A BR 0206955 A BR0206955 A BR 0206955A
Authority
BR
Brazil
Prior art keywords
compounds
cannabinoid receptor
prodrug
receptor binders
binders
Prior art date
Application number
BR0206955-5A
Other languages
English (en)
Portuguese (pt)
Inventor
Joseph A Kozlowski
Neng-Yang Shih
Brian J Lavey
Razia K Rizvi
Bandarpalle B Shankar
James M Spitler
Ling Tong
Ronald L Wolin
Michael K Wong
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of BR0206955A publication Critical patent/BR0206955A/pt

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
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    • C07C317/22—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
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    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
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    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
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    • C07C323/40—Y being a hydrogen or a carbon atom
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    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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RU2003127368A (ru) 2005-03-27
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CA2436659C (en) 2010-07-27
HUP0304060A3 (en) 2005-05-30
HUP0304060A2 (hu) 2004-04-28
US20030096844A1 (en) 2003-05-22
MXPA03007078A (es) 2003-11-18
JP4330341B2 (ja) 2009-09-16
KR20030075175A (ko) 2003-09-22
CZ20032122A3 (cs) 2003-10-15
US7718702B2 (en) 2010-05-18
CN1285572C (zh) 2006-11-22
WO2002062750A1 (en) 2002-08-15
AR032569A1 (es) 2003-11-12
AU2002306450B2 (en) 2005-09-22
JP2004530649A (ja) 2004-10-07

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