BR0116208A - Formulações de cuidados com a pele sem água compreendendo uréia micronizada e método de produção das mesmas - Google Patents
Formulações de cuidados com a pele sem água compreendendo uréia micronizada e método de produção das mesmasInfo
- Publication number
- BR0116208A BR0116208A BR0116208-0A BR0116208A BR0116208A BR 0116208 A BR0116208 A BR 0116208A BR 0116208 A BR0116208 A BR 0116208A BR 0116208 A BR0116208 A BR 0116208A
- Authority
- BR
- Brazil
- Prior art keywords
- skin care
- formulations
- waterless
- care formulations
- micronized urea
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 6
- 238000009472 formulation Methods 0.000 title abstract 5
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title abstract 3
- 239000004202 carbamide Substances 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000004519 grease Substances 0.000 abstract 2
- 239000002304 perfume Substances 0.000 abstract 2
- 230000037307 sensitive skin Effects 0.000 abstract 2
- 201000004624 Dermatitis Diseases 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000004166 Lanolin Substances 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 230000002009 allergenic effect Effects 0.000 abstract 1
- 208000010668 atopic eczema Diseases 0.000 abstract 1
- 239000000975 dye Substances 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
- 239000003205 fragrance Substances 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002430 hydrocarbons Chemical class 0.000 abstract 1
- 206010021198 ichthyosis Diseases 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 229940039717 lanolin Drugs 0.000 abstract 1
- 235000019388 lanolin Nutrition 0.000 abstract 1
- 239000000419 plant extract Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000001953 sensory effect Effects 0.000 abstract 1
- 238000009120 supportive therapy Methods 0.000 abstract 1
- OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Toxicology (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"FORMULAçõES DE CUIDADOS COM A PELE SEM áGUA COMPREENDENDO URéIA MICRONIZADA E MéTODO DE PRODUçãO DAS MESMAS". A invenção refere-se a formulações de cuidado com a pele médica sem água compreendendo uréia micronizada dispersa em uma fase graxa. A fase graxa consiste essencialmente em hidrocarbonetos e é essencialmente livre de ingredientes com potencial alergênico tais como perfumes ou substituintes de perfume (fragrâncias), conservantes, corantes, extratos de planta, PEGs, cetilestearil álcool, álcool de lanolina, álcoois inferiores, proteínas, assim sendo particularmente adequadas para pacientes com pele altamente sensível. As formulações da invenção têm propriedades sensoriais favoráveis e são estáveis por um período de tempo prolongado. As formulações são adequadas para cuidado com a pele médico, tal como para o tratamento de pele seca, sensível severamente afetada e para a terapia ou suporte de terapia de ictiose, psoríase, e eczema. A invenção também refere-se a métodos para produzir tais formulações de cuidado com a pele sem água.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25540100P | 2000-12-15 | 2000-12-15 | |
| EP00127556A EP1214931A1 (en) | 2000-12-15 | 2000-12-15 | Water-free skin care formulations comprising micronized urea and method of manufacturing the same |
| PCT/EP2001/014826 WO2002047643A1 (en) | 2000-12-15 | 2001-12-14 | Water-free skin care formulations comprising micronized urea and method of manufacturing the same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR0116208A true BR0116208A (pt) | 2003-12-23 |
| BRPI0116208B1 BRPI0116208B1 (pt) | 2015-09-08 |
| BRPI0116208B8 BRPI0116208B8 (pt) | 2021-05-25 |
Family
ID=26071667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0116208A BRPI0116208B8 (pt) | 2000-12-15 | 2001-12-14 | formulações de cuidados com a pele isentas de água compreendendo uréia micronizada e método de produção das mesmas. |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP1341515B1 (pt) |
| JP (1) | JP3626482B2 (pt) |
| KR (1) | KR100578446B1 (pt) |
| AT (1) | ATE341314T1 (pt) |
| AU (1) | AU2002233267A1 (pt) |
| BR (1) | BRPI0116208B8 (pt) |
| CA (1) | CA2432405C (pt) |
| CY (1) | CY1106302T1 (pt) |
| DE (1) | DE60123652T2 (pt) |
| DK (1) | DK1341515T3 (pt) |
| ES (1) | ES2273904T3 (pt) |
| HU (1) | HUP0302404A3 (pt) |
| IL (2) | IL156353A0 (pt) |
| MX (1) | MXPA03005239A (pt) |
| NO (1) | NO334330B1 (pt) |
| SI (1) | SI1341515T1 (pt) |
| WO (1) | WO2002047643A1 (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE486571T1 (de) * | 2006-08-28 | 2010-11-15 | Suess Hans R | Wasserfreie, harnstoffhaltige, dermatologische oder kosmetische zubereitung |
| DE102008006791B4 (de) * | 2008-01-30 | 2011-11-24 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System mit Harnstoff-Komponente und Verfahren zu dessen Herstellung |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3413569A1 (de) * | 1984-04-11 | 1985-10-24 | Röhm Pharma GmbH, 6108 Weiterstadt | Pharmazeutisches mittel zur psoriasis-therapie |
| DE3603859A1 (de) * | 1986-02-07 | 1987-08-13 | Roehm Pharma Gmbh | Abwaschbare topische zubereitung zur therapie der psoriasis |
| US5863546A (en) * | 1997-03-02 | 1999-01-26 | Swinehart; James M | Cosmetic composition |
-
2001
- 2001-12-14 MX MXPA03005239A patent/MXPA03005239A/es active IP Right Grant
- 2001-12-14 WO PCT/EP2001/014826 patent/WO2002047643A1/en active IP Right Grant
- 2001-12-14 AT AT01984853T patent/ATE341314T1/de active
- 2001-12-14 EP EP01984853A patent/EP1341515B1/en not_active Expired - Lifetime
- 2001-12-14 AU AU2002233267A patent/AU2002233267A1/en not_active Abandoned
- 2001-12-14 HU HU0302404A patent/HUP0302404A3/hu unknown
- 2001-12-14 ES ES01984853T patent/ES2273904T3/es not_active Expired - Lifetime
- 2001-12-14 SI SI200130670T patent/SI1341515T1/sl unknown
- 2001-12-14 JP JP2002549218A patent/JP3626482B2/ja not_active Expired - Fee Related
- 2001-12-14 KR KR1020037007942A patent/KR100578446B1/ko active IP Right Grant
- 2001-12-14 DE DE60123652T patent/DE60123652T2/de not_active Expired - Lifetime
- 2001-12-14 DK DK01984853T patent/DK1341515T3/da active
- 2001-12-14 IL IL15635301A patent/IL156353A0/xx active IP Right Grant
- 2001-12-14 BR BRPI0116208A patent/BRPI0116208B8/pt not_active IP Right Cessation
- 2001-12-14 CA CA002432405A patent/CA2432405C/en not_active Expired - Lifetime
-
2003
- 2003-06-09 IL IL156353A patent/IL156353A/en unknown
- 2003-06-13 NO NO20032693A patent/NO334330B1/no not_active IP Right Cessation
-
2006
- 2006-12-28 CY CY20061101856T patent/CY1106302T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002047643A1 (en) | 2002-06-20 |
| DE60123652D1 (de) | 2006-11-16 |
| NO20032693L (no) | 2003-08-13 |
| DE60123652T2 (de) | 2007-08-23 |
| DK1341515T3 (da) | 2007-01-29 |
| CA2432405A1 (en) | 2002-06-20 |
| NO20032693D0 (no) | 2003-06-13 |
| BRPI0116208B8 (pt) | 2021-05-25 |
| ATE341314T1 (de) | 2006-10-15 |
| EP1341515B1 (en) | 2006-10-04 |
| NO334330B1 (no) | 2014-02-03 |
| JP2004515522A (ja) | 2004-05-27 |
| KR20030061852A (ko) | 2003-07-22 |
| HUP0302404A2 (hu) | 2003-10-28 |
| HUP0302404A3 (en) | 2012-09-28 |
| JP3626482B2 (ja) | 2005-03-09 |
| MXPA03005239A (es) | 2003-09-25 |
| IL156353A0 (en) | 2004-01-04 |
| EP1341515A1 (en) | 2003-09-10 |
| ES2273904T3 (es) | 2007-05-16 |
| BRPI0116208B1 (pt) | 2015-09-08 |
| KR100578446B1 (ko) | 2006-05-12 |
| IL156353A (en) | 2007-06-17 |
| AU2002233267A1 (en) | 2002-06-24 |
| CA2432405C (en) | 2005-05-24 |
| CY1106302T1 (el) | 2011-10-12 |
| SI1341515T1 (sl) | 2007-02-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US9078838B2 (en) | Cosmetic or dermatological compositions comprising a mixture of essential oils, and its uses thereof, particularly for the care of sensitive or sensitized skin | |
| ATE294589T1 (de) | Fett(öl)haltiges mittel, enthaltend zwiebelextrakt, seine herstellung und seine verwendung zur pflege, vorbeugung oder behandlung von geschädigtem hautgewebe, insbesondere von narben | |
| JP2002193738A (ja) | 皮膚老化の徴候を処置する組成物における、少なくとも１種のツツジ科植物の少なくとも１種の抽出物の使用 | |
| JP2020529420A (ja) | ネフェリウム・ラパセウム（Ｎｅｐｈｅｌｉｕｍ ｌａｐｐａｃｅｕｍ）抽出物の新規な美容的使用 | |
| NL1004939C2 (nl) | Gebruik van een Eriobotrya japonica extract, in het bijzonder in het gebied van de cosmetica, voor het stimuleren van de synthesen van glucosaminoglycanen. | |
| BR112016007843B1 (pt) | Uso cosmético não-terapêutico de um extrato de hamamelis virginiana, e, método de cuidados cosméticos | |
| BRPI0116215B8 (pt) | formulações hipoalergênicas e não-irritantes para cuidado com a pele, bem como método para produção das mesmas | |
| KR960010002A (ko) | L-카르니틴염과 이를 함유한 피부질환 치료용 화장품 조성물 및 약제 조성물 | |
| JP4707437B2 (ja) | 天然保湿因子（ｎｍｆ）成分産生促進剤 | |
| JP2004091376A (ja) | 表皮角化正常化剤及びこれを含有する皮膚外用剤 | |
| KR20070118719A (ko) | 상피세포성장인자 및 섬유아세포성장인자를 함유하는 피부도포용 조성물 | |
| BR0116208A (pt) | Formulações de cuidados com a pele sem água compreendendo uréia micronizada e método de produção das mesmas | |
| ES2494928T3 (es) | Composición que comprende polisacáridos mucilaginosos derivados de Aloe barbadensis combinados con liposomas, procedimiento para la obtención de los mismos y su uso como protector solar, un agente antiacné, un regenerador epidérmico y un hidratante | |
| US11110117B2 (en) | Skin preparation composition for external use containing complex hyaluronic acid | |
| JP2018127407A (ja) | 表皮正常化剤並びにこれを含有する外用剤及び化粧料 | |
| JPS62209009A (ja) | 化粧料 | |
| JP3170540U (ja) | セダン草含有する化粧料 | |
| US20220175658A1 (en) | Skin care oil | |
| JP4132429B2 (ja) | 皮膚外用剤 | |
| JP2011190185A (ja) | アクアポリン３産生促進剤、及びそれを含有する化粧料 | |
| KR20230060659A (ko) | 각질제거용 화장료 조성물 및 이를 포함하는 패드 | |
| Somwanshi et al. | Cosmetic Science | |
| JP2024088811A (ja) | フィラグリン ｍＲＮＡ発現促進剤、ヒアルロン酸合成酵素３ ｍＲＮＡ発現促進剤、保湿剤、及び保湿用外用剤組成物 | |
| ITMI20111786A1 (it) | Composizione cosmetica e/o dermatologica. | |
| JP2004026836A (ja) | ヒドロキシチロソール、皮膚外用剤又は浴用剤への応用 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25D | Requested change of name of applicant approved |
Owner name: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) |
|
| B25A | Requested transfer of rights approved |
Owner name: INTENDIS GMBH (DE) Free format text: TRANSFERIDO DE: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Free format text: AS CLASSIFICACOES ANTERIORES ERAM: A61K 7/48 , A61K 31/00 Ipc: A61K 8/04 (2006.01), A61K 8/31 (2006.01), A61K 8/3 |
|
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 08/09/2015, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 14/12/2001 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |
|
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 20A ANUIDADE. |
|
| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2649 DE 13-10-2021 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |