BR0115058A - Partìculas de celulose para fármacos, processo para produzir as mesmas, e, grânulos esféricos contendo as partìculas de celulose para fármacos - Google Patents
Partìculas de celulose para fármacos, processo para produzir as mesmas, e, grânulos esféricos contendo as partìculas de celulose para fármacosInfo
- Publication number
- BR0115058A BR0115058A BR0115058-8A BR0115058A BR0115058A BR 0115058 A BR0115058 A BR 0115058A BR 0115058 A BR0115058 A BR 0115058A BR 0115058 A BR0115058 A BR 0115058A
- Authority
- BR
- Brazil
- Prior art keywords
- cellulose particles
- pharmaceutical
- pharmaceutical cellulose
- producing
- granules containing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/12—Powdering or granulating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B16/00—Regeneration of cellulose
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
- C08L1/02—Cellulose; Modified cellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2301/00—Characterised by the use of cellulose, modified cellulose or cellulose derivatives
- C08J2301/02—Cellulose; Modified cellulose
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Inorganic Chemistry (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
Abstract
"PARTìCULAS DE CELULOSE PARA FáRMACOS, PROCESSO PARA PRODUZIR AS MESMAS, E, GRâNULOS ESFéRICOS CONTENDO AS PARTìCULAS DE CELULOSE PARA FáRMACOS". As partículas de celulose para fármacos, que contém celulose microcristalina tendo um grau médio de polimerização de 60 a 350 em uma quantidade não menor do que 10%, têm uma densidade aparente após redução do volume por pressão de 0,60 a 0,95 g/ml, uma relação de aspecto não menor que 0,7, um fator de forma de 1,10 a 1,50, e um tamanho médio de partícula de 10 a 400 <109>m.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000338243 | 2000-11-06 | ||
PCT/JP2001/009691 WO2002036168A1 (fr) | 2000-11-06 | 2001-11-06 | Particules cellulosiques destinees a des preparations pharmaceutiques |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0115058A true BR0115058A (pt) | 2003-10-28 |
Family
ID=18813481
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0115058-8A BR0115058A (pt) | 2000-11-06 | 2001-11-06 | Partìculas de celulose para fármacos, processo para produzir as mesmas, e, grânulos esféricos contendo as partìculas de celulose para fármacos |
Country Status (12)
Country | Link |
---|---|
US (1) | US20040043964A1 (pt) |
EP (1) | EP1338288B1 (pt) |
JP (1) | JP4062436B2 (pt) |
KR (1) | KR100526285B1 (pt) |
CN (1) | CN1222318C (pt) |
AT (1) | ATE327770T1 (pt) |
AU (2) | AU2002211018B2 (pt) |
BR (1) | BR0115058A (pt) |
CA (1) | CA2427991C (pt) |
DE (1) | DE60120211T2 (pt) |
TW (1) | TWI290471B (pt) |
WO (1) | WO2002036168A1 (pt) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1634908B1 (en) | 2003-05-30 | 2017-01-11 | Asahi Kasei Kabushiki Kaisha | Cellulose powder |
EP1712583B1 (en) | 2004-01-30 | 2020-09-16 | Asahi Kasei Kabushiki Kaisha | Porous cellulose aggregate and formed product composition comprising the same |
JP5240822B2 (ja) * | 2005-04-22 | 2013-07-17 | 旭化成ケミカルズ株式会社 | 多孔質セルロース凝集体及びその成型体組成物 |
JP2009542368A (ja) * | 2006-06-30 | 2009-12-03 | ノバビジョン, インコーポレイテッド | 偏心視の診断および治療システム |
USRE45810E1 (en) * | 2006-07-19 | 2015-11-24 | Asahi Kasei Chemicals Corporation | Process for producing spherical base granule comprising easily water-soluble drug |
CN101495097A (zh) * | 2006-07-26 | 2009-07-29 | 旭化成化学株式会社 | 球形素颗粒及其制造方法 |
WO2008112565A2 (en) * | 2007-03-09 | 2008-09-18 | Anthony Manganaro | Method and composition for treating cancer |
US8298585B2 (en) | 2007-06-06 | 2012-10-30 | Asahi Kasei Chemicals Corporation | Cellulose-based fine core particle and process for producing the same |
US20100055180A1 (en) * | 2007-10-10 | 2010-03-04 | Mallinckrodt Baker, Inc. | Directly Compressible Granular Microcrystalline Cellulose Based Excipient, Manufacturing Process and Use Thereof |
MY164765A (en) * | 2007-10-10 | 2018-01-30 | Avantor Performance Mat Llc | Directly compressible high functionality granular microcrystalline cellulose based excipient, manufacturing process and use thereof |
JP2009155215A (ja) * | 2007-12-25 | 2009-07-16 | Freunt Ind Co Ltd | 球形粒及びその製造方法並びに放出制御製剤の製造方法 |
JP2009263303A (ja) * | 2008-04-28 | 2009-11-12 | Freunt Ind Co Ltd | 球形顆粒及びその製造方法 |
US9132195B2 (en) * | 2008-05-21 | 2015-09-15 | Asahi Kasei Chemicals Corporation | Cellulose powder having excellent segregation preventive effect, and compositions thereof |
WO2010001574A1 (ja) * | 2008-07-01 | 2010-01-07 | 沢井製薬株式会社 | タムスロシン塩酸塩を含有する球形微粒子の製造方法 |
JP2012509329A (ja) * | 2008-11-19 | 2012-04-19 | アバントール パフォーマンス マテリアルズ, インコーポレイテッド | 直接圧縮可能で高機能性な顆粒状の微結晶性セルロースベース賦形剤、それらの製造プロセスおよび使用 |
WO2011049203A1 (ja) | 2009-10-22 | 2011-04-28 | 旭化成ケミカルズ株式会社 | メタクリル系樹脂、その成形体及びメタクリル系樹脂の製造方法 |
JP2011207851A (ja) * | 2010-03-30 | 2011-10-20 | Asahi Kasei Chemicals Corp | 膨潤性の球状核 |
UA111162C2 (uk) | 2010-08-04 | 2016-04-11 | Флекшен Терап'Ютікс, Інк. | Ін'єкційна композиція ацетоніду триамцинолону для лікування болю |
CA2843139C (en) * | 2011-08-04 | 2019-09-24 | Flexion Therapeutics, Inc. | Corticosteroids for the treatment of joint pain |
KR20160094987A (ko) * | 2013-12-04 | 2016-08-10 | 다우 글로벌 테크놀로지스 엘엘씨 | 셀룰로오스 유도체와 액체 희석제의 혼합물의 제조 방법 |
WO2016024493A1 (ja) * | 2014-08-12 | 2016-02-18 | 旭化成ケミカルズ株式会社 | 微小セルロース粉末 |
JP5877889B2 (ja) * | 2014-11-07 | 2016-03-08 | 旭化成ケミカルズ株式会社 | 膨潤性の球状核 |
US20190127641A1 (en) * | 2015-11-30 | 2019-05-02 | Growth Partner, Limited | Agent for decreasing fluidity of solid-liquid mixture, and method for producing low-fluidity mixture |
JP6366794B2 (ja) * | 2016-07-28 | 2018-08-01 | 大原薬品工業株式会社 | 原薬の化学的安定性や服用感を向上した、口腔内崩壊錠 |
GB201715387D0 (en) | 2017-09-22 | 2017-11-08 | Cambridge Entpr Ltd | Treatment of polymer particles |
US11813360B2 (en) * | 2018-07-27 | 2023-11-14 | Chiesi Farmaceutici S.P.A. | Carrier particles for dry powder formulations for inhalation |
JP7199871B2 (ja) * | 2018-08-10 | 2023-01-06 | 日揮触媒化成株式会社 | 多孔質セルロース粒子とその製造方法、および洗浄用化粧料 |
JP7265331B2 (ja) * | 2018-09-28 | 2023-04-26 | 日揮触媒化成株式会社 | 多孔質セルロース粒子および化粧料 |
SG11202106839XA (en) * | 2018-12-27 | 2021-07-29 | Asahi Chemical Ind | Cellulose powder, use thereof, and tablets |
JP7149885B2 (ja) * | 2019-03-22 | 2022-10-07 | 株式会社ダイセル | セルロース誘導体粒子、化粧品組成物及びセルロース誘導体粒子の製造方法 |
WO2020218518A1 (ja) * | 2019-04-25 | 2020-10-29 | 富士製薬工業株式会社 | 医薬製剤およびその製造方法 |
CA3143606A1 (en) | 2019-07-05 | 2021-01-14 | Swedish Match North Europe Ab | An oral pouched nicotine product including a filling material comprising nicotine-containing particles |
JP2023506701A (ja) * | 2019-11-20 | 2023-02-20 | スウィーディッシュ・マッチ・ノース・ヨーロップ・アーベー | ニコチン粒子を含有する充填材を含む経口袋状ニコチン製品 |
JP2021095470A (ja) * | 2019-12-16 | 2021-06-24 | 王子ホールディングス株式会社 | 粉末状セルロース |
CN113480669B (zh) * | 2021-07-13 | 2022-08-12 | 安徽山河药用辅料股份有限公司 | 一种低松密度交联羧甲纤维素钠的制备方法 |
CN117686671B (zh) * | 2023-12-11 | 2024-09-13 | 国药集团容生制药有限公司 | 一种优化恩格列净片剂溶出曲线及体内生物等效性的方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU508480B2 (en) * | 1977-04-13 | 1980-03-20 | Asahi Kasei Kogyo Kabushiki Kaisha | Microcrystalline cellulose excipient and pharmaceutical composition containing thesame |
JP2976116B2 (ja) * | 1989-09-27 | 1999-11-10 | 旭化成工業株式会社 | 球状セルロース粒子の製造方法 |
DE69111287T2 (de) * | 1990-04-18 | 1995-12-21 | Asahi Chemical Ind | Kugelförmige Keimkerne, kugelförmige Granulate sowie Verfahren zu deren Herstellung. |
US5322702A (en) * | 1992-06-15 | 1994-06-21 | Fmc Corporation | Microgranular protein opacifying material |
US5417984A (en) * | 1992-12-14 | 1995-05-23 | Biocontrol, Inc. | Low crystallinity cellulose excipients |
CN1296387C (zh) * | 2000-07-05 | 2007-01-24 | 旭化成株式会社 | 纤维素粉末 |
-
2001
- 2001-11-06 WO PCT/JP2001/009691 patent/WO2002036168A1/ja active IP Right Grant
- 2001-11-06 AT AT01979030T patent/ATE327770T1/de not_active IP Right Cessation
- 2001-11-06 DE DE60120211T patent/DE60120211T2/de not_active Expired - Lifetime
- 2001-11-06 AU AU2002211018A patent/AU2002211018B2/en not_active Ceased
- 2001-11-06 AU AU1101802A patent/AU1101802A/xx active Pending
- 2001-11-06 CN CNB018184219A patent/CN1222318C/zh not_active Expired - Fee Related
- 2001-11-06 TW TW090127553A patent/TWI290471B/zh not_active IP Right Cessation
- 2001-11-06 BR BR0115058-8A patent/BR0115058A/pt not_active Application Discontinuation
- 2001-11-06 JP JP2002538977A patent/JP4062436B2/ja not_active Expired - Lifetime
- 2001-11-06 US US10/415,979 patent/US20040043964A1/en not_active Abandoned
- 2001-11-06 EP EP01979030A patent/EP1338288B1/en not_active Expired - Lifetime
- 2001-11-06 KR KR10-2003-7006103A patent/KR100526285B1/ko not_active IP Right Cessation
- 2001-11-06 CA CA002427991A patent/CA2427991C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1338288B1 (en) | 2006-05-31 |
ATE327770T1 (de) | 2006-06-15 |
KR100526285B1 (ko) | 2005-11-08 |
EP1338288A1 (en) | 2003-08-27 |
US20040043964A1 (en) | 2004-03-04 |
WO2002036168A1 (fr) | 2002-05-10 |
CN1473054A (zh) | 2004-02-04 |
DE60120211T2 (de) | 2007-04-12 |
AU1101802A (en) | 2002-05-15 |
JP4062436B2 (ja) | 2008-03-19 |
KR20030051773A (ko) | 2003-06-25 |
DE60120211D1 (de) | 2006-07-06 |
JPWO2002036168A1 (ja) | 2004-03-18 |
CA2427991A1 (en) | 2003-05-05 |
AU2002211018B2 (en) | 2004-08-05 |
CN1222318C (zh) | 2005-10-12 |
CA2427991C (en) | 2008-01-22 |
TWI290471B (en) | 2007-12-01 |
EP1338288A4 (en) | 2004-12-29 |
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Legal Events
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8 E 13 DA LPI |
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B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |