BR0114390A - éteres de 7-desmetilrapamicina - Google Patents

éteres de 7-desmetilrapamicina

Info

Publication number
BR0114390A
BR0114390A BR0114390-5A BR0114390A BR0114390A BR 0114390 A BR0114390 A BR 0114390A BR 0114390 A BR0114390 A BR 0114390A BR 0114390 A BR0114390 A BR 0114390A
Authority
BR
Brazil
Prior art keywords
desmethylrapamycin
ethers
demethyrapamycin
aethers
useful
Prior art date
Application number
BR0114390-5A
Other languages
English (en)
Inventor
Tianmin Zhu
Robin Enever
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of BR0114390A publication Critical patent/BR0114390A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

"éTERES DE 7-DESMETILRAPAMICINA". Esta invenção refere-se a éteres de 7-desmetilrapamicina que são úteis em induzir a imunossupressão e no tratamento de rejeição de transplante, doenças auto-imunes, tumores sólidos, infecções fúngicas, e doença vascular.
BR0114390-5A 2000-10-02 2001-09-28 éteres de 7-desmetilrapamicina BR0114390A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23746900P 2000-10-02 2000-10-02
PCT/US2001/030685 WO2002028867A2 (en) 2000-10-02 2001-09-28 Ethers of 7-desmethylrapamycin for use in immunosuppression

Publications (1)

Publication Number Publication Date
BR0114390A true BR0114390A (pt) 2003-08-26

Family

ID=22893849

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0114390-5A BR0114390A (pt) 2000-10-02 2001-09-28 éteres de 7-desmetilrapamicina

Country Status (9)

Country Link
US (1) US6440991B1 (pt)
EP (1) EP1335924A2 (pt)
JP (1) JP2004510777A (pt)
CN (1) CN1468247A (pt)
AU (1) AU2001294932A1 (pt)
BR (1) BR0114390A (pt)
CA (1) CA2423898A1 (pt)
MX (1) MXPA03002856A (pt)
WO (1) WO2002028867A2 (pt)

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MXPA03002856A (es) 2003-07-14
CA2423898A1 (en) 2002-04-11
AU2001294932A1 (en) 2002-04-15
US6440991B1 (en) 2002-08-27
WO2002028867A3 (en) 2002-08-29
JP2004510777A (ja) 2004-04-08
WO2002028867A2 (en) 2002-04-11
US20020061905A1 (en) 2002-05-23
EP1335924A2 (en) 2003-08-20

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