BR0112128A - Processo para a preparação de (r)-2-alquil-3-fenil-1-propanóis - Google Patents
Processo para a preparação de (r)-2-alquil-3-fenil-1-propanóisInfo
- Publication number
- BR0112128A BR0112128A BR0112128-6A BR0112128A BR0112128A BR 0112128 A BR0112128 A BR 0112128A BR 0112128 A BR0112128 A BR 0112128A BR 0112128 A BR0112128 A BR 0112128A
- Authority
- BR
- Brazil
- Prior art keywords
- alkyl
- alkoxy
- propanols
- phenyl
- acid esters
- Prior art date
Links
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000003935 benzaldehydes Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000012217 deletion Methods 0.000 abstract 1
- 230000037430 deletion Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000003151 propanoic acid esters Chemical class 0.000 abstract 1
- 230000000707 stereoselective effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/17—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH13182000 | 2000-07-03 | ||
| PCT/CH2001/000398 WO2002002487A1 (en) | 2000-07-03 | 2001-06-26 | Process for the preparation of (r)-2-alkyl-3-phenyl-1-propanols |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0112128A true BR0112128A (pt) | 2003-05-13 |
Family
ID=4565375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0112128-6A BR0112128A (pt) | 2000-07-03 | 2001-06-26 | Processo para a preparação de (r)-2-alquil-3-fenil-1-propanóis |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6881868B2 (enExample) |
| EP (1) | EP1296912B1 (enExample) |
| JP (1) | JP4841799B2 (enExample) |
| CN (1) | CN1293026C (enExample) |
| AR (1) | AR029558A1 (enExample) |
| AT (1) | ATE316518T1 (enExample) |
| AU (1) | AU2001273762A1 (enExample) |
| BR (1) | BR0112128A (enExample) |
| CA (1) | CA2414844C (enExample) |
| DE (1) | DE60116874T2 (enExample) |
| TW (1) | TW575537B (enExample) |
| WO (1) | WO2002002487A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE323787T1 (de) * | 2002-12-18 | 2006-05-15 | Cardinal Cg Co | Plasmaunterstützte filmabscheidung |
| DE102005052195A1 (de) | 2005-10-28 | 2007-05-03 | Reuter Chemischer Apparatebau Kg | Verfahren zur Herstellung von chiralen Octensäurederivaten |
| BRPI0706778A2 (pt) * | 2006-01-30 | 2011-04-05 | Speedel Experimenta Ag | processos para a preparação estéreo-seletiva de álcoois a partir de compostos alfa, beta-insaturados |
| EP1921069A1 (de) * | 2006-11-08 | 2008-05-14 | Speedel Experimenta AG | Verfahren zur Herstellung von 2-Alkyl-3-heterocyclyl-prop-2-en-1-olen |
| TW200837046A (en) * | 2006-11-08 | 2008-09-16 | Speedel Experimenta Ag | Process for preparing organic compounds |
| EP1939182A1 (de) * | 2006-12-22 | 2008-07-02 | Speedel Experimenta AG | Verfahren zur Herstellung von (R oder S)-2-Alkyl-3-heterocyclyl-1-propanolen |
| EP1958666A1 (en) | 2007-02-13 | 2008-08-20 | Speedel Experimenta AG | Heterocyclic-substituted alkanamides as therapeutic compounds |
| AR065792A1 (es) * | 2007-03-21 | 2009-07-01 | Speedel Experimenta Ag | Proceso para preparar (r o s) -5- (1 -azido-3-(6-metoxi-5-(3-metoxi-propoxi) -piridin-3-ilmetil) -4-metil- pentil) -3-alquil-dihidro-furan-2-ona |
| EP2178816A1 (en) * | 2007-07-11 | 2010-04-28 | DSM Fine Chemicals Austria Nfg GmbH & Co KG | Alpha-substituted , -unsaturated e- or z-aldehydes, use thereof, and processes for their preparation , |
| EP2173696A1 (en) * | 2007-07-11 | 2010-04-14 | DSM IP Assets B.V. | Preparation of a saturated aldehyde |
| DE102007049039A1 (de) | 2007-10-11 | 2009-04-16 | Reuter Chemischer Apparatebau Kg | Verfahren zur Herstellung von 8-Hydrazino-8-Aryl-Octanoylderivaten und deren Verwendung |
| US8203005B2 (en) | 2009-10-29 | 2012-06-19 | Carbo Design Llc | Manufacturing process for enantiomerically pure 8-aryloctanoic acids as Aliskiren |
| TW201202178A (en) | 2010-06-04 | 2012-01-16 | Chemo Iberica Sa | Process for producing Aliskiren |
| US8703976B2 (en) | 2011-10-02 | 2014-04-22 | Milan Soukup | Manufacturing process for 8-aryloctanoic acids such as Aliskiren |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2709268A1 (de) * | 1977-03-03 | 1978-09-07 | Merck Patent Gmbh | Diphenylaetherderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen enthaltend diese verbindungen |
| ZA838831B (en) * | 1982-12-31 | 1984-07-25 | Fujisawa Pharmaceutical Co | New nitro aliphatic compounds,process for preparation thereof and use thereof |
| JPH0694441B2 (ja) * | 1992-11-18 | 1994-11-24 | 和光純薬工業株式会社 | ＤＬ−スレオ−２−（３，４−ジ低級アルキルオキシ−α−ヒドロキシベンジル）イソ吉草酸アルキル及びその製造法 |
| MY119161A (en) * | 1994-04-18 | 2005-04-30 | Novartis Ag | Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities |
| DE19516968A1 (de) * | 1995-05-12 | 1996-11-14 | Basf Ag | Optisch aktive Phosphine, deren Herstellung, deren Metallkomplexe und Anwendung in der asymmetrischen Synthese |
| CN100482632C (zh) * | 2000-07-03 | 2009-04-29 | 斯皮德尔药品公司 | (r)-2-烷基-3-苯基丙酸的制备 |
-
2001
- 2001-06-26 BR BR0112128-6A patent/BR0112128A/pt not_active IP Right Cessation
- 2001-06-26 AT AT01940046T patent/ATE316518T1/de active
- 2001-06-26 US US10/312,992 patent/US6881868B2/en not_active Expired - Fee Related
- 2001-06-26 CN CNB018122337A patent/CN1293026C/zh not_active Expired - Fee Related
- 2001-06-26 JP JP2002507746A patent/JP4841799B2/ja not_active Expired - Fee Related
- 2001-06-26 WO PCT/CH2001/000398 patent/WO2002002487A1/en not_active Ceased
- 2001-06-26 AU AU2001273762A patent/AU2001273762A1/en not_active Abandoned
- 2001-06-26 CA CA2414844A patent/CA2414844C/en not_active Expired - Fee Related
- 2001-06-26 DE DE60116874T patent/DE60116874T2/de not_active Expired - Lifetime
- 2001-06-26 EP EP01940046A patent/EP1296912B1/en not_active Expired - Lifetime
- 2001-06-29 TW TW90115928A patent/TW575537B/zh not_active IP Right Cessation
- 2001-07-03 AR ARP010103176A patent/AR029558A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002002487A1 (en) | 2002-01-10 |
| US6881868B2 (en) | 2005-04-19 |
| DE60116874D1 (de) | 2006-04-13 |
| CA2414844A1 (en) | 2002-01-10 |
| CN1440374A (zh) | 2003-09-03 |
| US20040092766A1 (en) | 2004-05-13 |
| JP2004502656A (ja) | 2004-01-29 |
| CN1293026C (zh) | 2007-01-03 |
| CA2414844C (en) | 2010-05-11 |
| TW575537B (en) | 2004-02-11 |
| DE60116874T2 (de) | 2006-11-02 |
| AR029558A1 (es) | 2003-07-02 |
| AU2001273762A1 (en) | 2002-01-14 |
| EP1296912A1 (en) | 2003-04-02 |
| JP4841799B2 (ja) | 2011-12-21 |
| ATE316518T1 (de) | 2006-02-15 |
| EP1296912B1 (en) | 2006-01-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 12A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2258 DE 15/04/2014. |