BR0111627A - Preservação criogênica de material biologicamente ativo usando congelamento de alta temperatura - Google Patents
Preservação criogênica de material biologicamente ativo usando congelamento de alta temperaturaInfo
- Publication number
- BR0111627A BR0111627A BR0111627-4A BR0111627A BR0111627A BR 0111627 A BR0111627 A BR 0111627A BR 0111627 A BR0111627 A BR 0111627A BR 0111627 A BR0111627 A BR 0111627A
- Authority
- BR
- Brazil
- Prior art keywords
- cooling fluid
- high temperature
- active material
- biologically active
- formation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
- A01N1/0252—Temperature controlling refrigerating apparatus, i.e. devices used to actively control the temperature of a designated internal volume, e.g. refrigerators, freeze-drying apparatus or liquid nitrogen baths
- A01N1/0257—Stationary or portable vessels generating cryogenic temperatures
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2400/00—General features of, or devices for refrigerators, cold rooms, ice-boxes, or for cooling or freezing apparatus not covered by any other subclass
- F25D2400/30—Quick freezing
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Thermal Sciences (AREA)
- Physics & Mathematics (AREA)
- Mechanical Engineering (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Cultivation Of Plants (AREA)
Abstract
"PRESERVAçãO CRIOGêNICA DE MATERIAL BIOLOGICAMENTE ATIVO USANDO CONGELAMENTO DE ALTA TEMPERATURA". A presente invenção refere-se a um material biológico viável que é criogenicamente preservado (criopreservação) ao quimicamente preparar o material para congelamento, imergir o material em um tanque de fluido de resfriamento, e circular o fluido de resfriamento adiante do material a uma velocidade e temperatura predeterminadas substancialmente constante para congelar o material. Um método de acordo com a presente invenção congela o material biológico suficientemente rápido para evitar a formação de cristais de gelo no interior das estruturas celulares (vitrificação) . A temperatura do fluido de resfriamento é de forma preferida entre -20<198>C e -30<198>C, que é suficientemente morno para minimizar a formação de fraturas de tensão nas membranas celulares em virtude de mudanças térmicas. As células congeladas ao se usar o método de acordo com a presente invenção mostrou ser dotado de um coeficiente de sobrevivência de 80 por cento, o que é significativamente maior do que os outros métodos de criopreservação.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21091300P | 2000-06-12 | 2000-06-12 | |
| PCT/US2001/018916 WO2001095716A2 (en) | 2000-06-12 | 2001-06-12 | High temperature cryogenic preservation of biologically active material |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0111627A true BR0111627A (pt) | 2003-05-06 |
Family
ID=22784822
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0111627-4A BR0111627A (pt) | 2000-06-12 | 2001-06-12 | Preservação criogênica de material biologicamente ativo usando congelamento de alta temperatura |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US6519954B1 (pt) |
| EP (1) | EP1311153B1 (pt) |
| JP (1) | JP2004503473A (pt) |
| KR (1) | KR20030034087A (pt) |
| CN (1) | CN1434679A (pt) |
| AT (1) | ATE311103T1 (pt) |
| AU (2) | AU6835901A (pt) |
| BR (1) | BR0111627A (pt) |
| CA (1) | CA2410896A1 (pt) |
| DE (1) | DE60115460T2 (pt) |
| IL (1) | IL153175A0 (pt) |
| MX (1) | MXPA02012138A (pt) |
| NO (1) | NO20025851L (pt) |
| NZ (1) | NZ523572A (pt) |
| RU (1) | RU2003100535A (pt) |
| WO (1) | WO2001095716A2 (pt) |
| ZA (1) | ZA200209843B (pt) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA02011219A (es) * | 2000-05-18 | 2004-08-19 | Supachill Internat Pty Ltd | Metodo de enfriamiento para refrigeracion o congelacion a alta velocidad controlada. |
| CN1685210A (zh) * | 2001-01-02 | 2005-10-19 | 苏帕契勒技术控股有限公司 | 为组织学和病理学检验制备组织样品的方法和系统 |
| US6656380B2 (en) | 2001-10-16 | 2003-12-02 | Supachill Technologies Pty. Ltd. | Super-coolable composition having long-duration phase change capability, process for preparation of same, process for super-cooling same and articles comprising same |
| US11243494B2 (en) | 2002-07-31 | 2022-02-08 | Abs Global, Inc. | Multiple laminar flow-based particle and cellular separation with laser steering |
| US20050241333A1 (en) * | 2003-12-03 | 2005-11-03 | Hamilton Robert W | Rate-controlled freezer and cooling methods thereof |
| DK176397B1 (da) * | 2005-10-07 | 2007-11-26 | Gram Equipment As | Fremgangsmåde og styring af en termisk behandlingsenhed samt termisk behandlingsenhed |
| JP5100998B2 (ja) * | 2005-10-26 | 2012-12-19 | 国立大学法人広島大学 | 抜歯体の凍結保存方法 |
| US8794012B2 (en) * | 2007-11-09 | 2014-08-05 | Praxair Technology, Inc. | Method and system for controlled rate freezing of biological material |
| US7613330B2 (en) * | 2006-04-03 | 2009-11-03 | Jbs Swift & Company | Methods and systems for tracking and managing livestock through the production process |
| US7606394B2 (en) * | 2006-04-03 | 2009-10-20 | Jbs Swift & Company | Methods and systems for administering a drug program related to livestock |
| US9159126B2 (en) | 2006-04-03 | 2015-10-13 | Jbs Usa, Llc | System and method for analyzing and processing food product |
| US7892076B2 (en) | 2006-05-22 | 2011-02-22 | Swift & Company | Multibar apparatus and method for electrically stimulating a carcass |
| US8030063B2 (en) | 2008-06-18 | 2011-10-04 | The Cleveland Clinic Foundation | Systems and methods for vitrifying tissue |
| US9700038B2 (en) | 2009-02-25 | 2017-07-11 | Genea Limited | Cryopreservation of biological cells and tissues |
| PL2575442T3 (pl) | 2010-05-28 | 2023-10-30 | Genea Ip Holdings Pty Limited | Ulepszone urządzenie i metody mikromanipulacji oraz przechowywania |
| US10908066B2 (en) | 2010-11-16 | 2021-02-02 | 1087 Systems, Inc. | Use of vibrational spectroscopy for microfluidic liquid measurement |
| JP6012164B2 (ja) * | 2011-11-25 | 2016-10-25 | 住友化学株式会社 | 多能性幹細胞由来の組織の凍結保存方法 |
| CN103416394A (zh) * | 2012-11-01 | 2013-12-04 | 上海理工大学 | 血管干燥保存的方法 |
| US8961904B2 (en) | 2013-07-16 | 2015-02-24 | Premium Genetics (Uk) Ltd. | Microfluidic chip |
| US11796449B2 (en) | 2013-10-30 | 2023-10-24 | Abs Global, Inc. | Microfluidic system and method with focused energy apparatus |
| US10180388B2 (en) | 2015-02-19 | 2019-01-15 | 1087 Systems, Inc. | Scanning infrared measurement system |
| JP6823074B2 (ja) | 2015-12-07 | 2021-01-27 | クーパーサージカル・インコーポレイテッドＣｏｏｐｅｒＳｕｒｇｉｃａｌ， Ｉｎｃ． | 低温検体キャリヤおよび関連する方法 |
| US11377276B2 (en) * | 2016-08-05 | 2022-07-05 | Bachem Holding Ag | Drying container |
| GB201621645D0 (en) | 2016-12-19 | 2017-02-01 | Asymptote Ltd | Shipping container |
| BR112020023607A2 (pt) | 2018-05-23 | 2021-02-17 | Abs Global, Inc. | sistemas e métodos para focalização de partículas em microcanais |
| FR3084991B1 (fr) | 2018-08-14 | 2020-11-06 | Cryocapcell | Dispositif de cryogenisation a commande hydraulique |
| CN117413819A (zh) * | 2019-04-18 | 2024-01-19 | 艾步思国际有限责任公司 | 用于连续添加冷冻保护剂的系统和工艺 |
| US11628439B2 (en) | 2020-01-13 | 2023-04-18 | Abs Global, Inc. | Single-sheath microfluidic chip |
| US20240009295A1 (en) * | 2020-11-19 | 2024-01-11 | Upkara, Inc. | Ambient temperature lipid particle storage systems and methods |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1238618B (de) | 1959-11-09 | 1967-04-13 | Union Carbide Corp | Verfahren zur Konservierung biologischer Substanzen |
| US4429542A (en) * | 1981-08-10 | 1984-02-07 | Hoxan Corporation | Method of freezing fertilized ova, spermatozoa or the like and apparatus therefor |
| US4676070A (en) * | 1984-11-30 | 1987-06-30 | The Board Of Regents, The University Of Texas | Apparatus and method for cryopreparing biological tissue |
| US4848094A (en) * | 1988-04-29 | 1989-07-18 | Union Carbide Corporation | Droplet freezing method and apparatus |
| JPH02126075A (ja) * | 1988-11-01 | 1990-05-15 | Yuji Yamashita | 農水産物や加工食品類の急速冷凍装置 |
| US5029447A (en) | 1989-08-04 | 1991-07-09 | Cryo-Cell International Inc. | Multichamber storage apparatus and related method |
| NZ235020A (en) | 1989-08-22 | 1993-05-26 | Allan John Cassell | Chiller: coolant circulated through bowl containing articles to be chilled |
| US5003787A (en) | 1990-01-18 | 1991-04-02 | Savant Instruments | Cell preservation system |
| US5222367A (en) * | 1990-09-10 | 1993-06-29 | Technican Company, Ltd. | Method of freezing food utilizing a set agitator |
-
2000
- 2000-09-06 US US09/655,807 patent/US6519954B1/en not_active Expired - Fee Related
-
2001
- 2001-06-12 RU RU2003100535/15A patent/RU2003100535A/ru not_active Application Discontinuation
- 2001-06-12 DE DE60115460T patent/DE60115460T2/de not_active Expired - Fee Related
- 2001-06-12 IL IL15317501A patent/IL153175A0/xx unknown
- 2001-06-12 CA CA002410896A patent/CA2410896A1/en not_active Abandoned
- 2001-06-12 EP EP01946288A patent/EP1311153B1/en not_active Expired - Lifetime
- 2001-06-12 AU AU6835901A patent/AU6835901A/xx active Pending
- 2001-06-12 KR KR1020027016624A patent/KR20030034087A/ko not_active Application Discontinuation
- 2001-06-12 MX MXPA02012138A patent/MXPA02012138A/es active IP Right Grant
- 2001-06-12 JP JP2002509912A patent/JP2004503473A/ja not_active Withdrawn
- 2001-06-12 AU AU2001268359A patent/AU2001268359B2/en not_active Ceased
- 2001-06-12 NZ NZ523572A patent/NZ523572A/en unknown
- 2001-06-12 CN CN01810856A patent/CN1434679A/zh active Pending
- 2001-06-12 WO PCT/US2001/018916 patent/WO2001095716A2/en active IP Right Grant
- 2001-06-12 BR BR0111627-4A patent/BR0111627A/pt not_active IP Right Cessation
- 2001-06-12 AT AT01946288T patent/ATE311103T1/de not_active IP Right Cessation
-
2002
- 2002-12-04 ZA ZA200209843A patent/ZA200209843B/en unknown
- 2002-12-05 NO NO20025851A patent/NO20025851L/no not_active Application Discontinuation
- 2002-12-13 US US10/319,454 patent/US20030154729A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN1434679A (zh) | 2003-08-06 |
| EP1311153B1 (en) | 2005-11-30 |
| AU2001268359B2 (en) | 2006-01-19 |
| NZ523572A (en) | 2004-05-28 |
| WO2001095716A2 (en) | 2001-12-20 |
| DE60115460D1 (de) | 2006-01-05 |
| NO20025851L (no) | 2003-02-11 |
| WO2001095716A3 (en) | 2002-05-23 |
| CA2410896A1 (en) | 2001-12-20 |
| JP2004503473A (ja) | 2004-02-05 |
| DE60115460T2 (de) | 2006-08-24 |
| IL153175A0 (en) | 2003-06-24 |
| ZA200209843B (en) | 2004-07-05 |
| RU2003100535A (ru) | 2004-07-10 |
| EP1311153A2 (en) | 2003-05-21 |
| AU6835901A (en) | 2001-12-24 |
| US20030154729A1 (en) | 2003-08-21 |
| NO20025851D0 (no) | 2002-12-05 |
| KR20030034087A (ko) | 2003-05-01 |
| ATE311103T1 (de) | 2005-12-15 |
| MXPA02012138A (es) | 2004-08-19 |
| US6519954B1 (en) | 2003-02-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A , 9A E 10A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2112 DE 28/06/2011. |