BR0111627A - Preservação criogênica de material biologicamente ativo usando congelamento de alta temperatura - Google Patents
Preservação criogênica de material biologicamente ativo usando congelamento de alta temperaturaInfo
- Publication number
- BR0111627A BR0111627A BR0111627-4A BR0111627A BR0111627A BR 0111627 A BR0111627 A BR 0111627A BR 0111627 A BR0111627 A BR 0111627A BR 0111627 A BR0111627 A BR 0111627A
- Authority
- BR
- Brazil
- Prior art keywords
- cooling fluid
- high temperature
- active material
- biologically active
- formation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
- A01N1/0252—Temperature controlling refrigerating apparatus, i.e. devices used to actively control the temperature of a designated internal volume, e.g. refrigerators, freeze-drying apparatus or liquid nitrogen baths
- A01N1/0257—Stationary or portable vessels generating cryogenic temperatures
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2400/00—General features of, or devices for refrigerators, cold rooms, ice-boxes, or for cooling or freezing apparatus not covered by any other subclass
- F25D2400/30—Quick freezing
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Thermal Sciences (AREA)
- Physics & Mathematics (AREA)
- Mechanical Engineering (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Cultivation Of Plants (AREA)
Abstract
"PRESERVAçãO CRIOGêNICA DE MATERIAL BIOLOGICAMENTE ATIVO USANDO CONGELAMENTO DE ALTA TEMPERATURA". A presente invenção refere-se a um material biológico viável que é criogenicamente preservado (criopreservação) ao quimicamente preparar o material para congelamento, imergir o material em um tanque de fluido de resfriamento, e circular o fluido de resfriamento adiante do material a uma velocidade e temperatura predeterminadas substancialmente constante para congelar o material. Um método de acordo com a presente invenção congela o material biológico suficientemente rápido para evitar a formação de cristais de gelo no interior das estruturas celulares (vitrificação) . A temperatura do fluido de resfriamento é de forma preferida entre -20<198>C e -30<198>C, que é suficientemente morno para minimizar a formação de fraturas de tensão nas membranas celulares em virtude de mudanças térmicas. As células congeladas ao se usar o método de acordo com a presente invenção mostrou ser dotado de um coeficiente de sobrevivência de 80 por cento, o que é significativamente maior do que os outros métodos de criopreservação.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21091300P | 2000-06-12 | 2000-06-12 | |
| PCT/US2001/018916 WO2001095716A2 (en) | 2000-06-12 | 2001-06-12 | High temperature cryogenic preservation of biologically active material |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0111627A true BR0111627A (pt) | 2003-05-06 |
Family
ID=22784822
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0111627-4A BR0111627A (pt) | 2000-06-12 | 2001-06-12 | Preservação criogênica de material biologicamente ativo usando congelamento de alta temperatura |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US6519954B1 (pt) |
| EP (1) | EP1311153B1 (pt) |
| JP (1) | JP2004503473A (pt) |
| KR (1) | KR20030034087A (pt) |
| CN (1) | CN1434679A (pt) |
| AT (1) | ATE311103T1 (pt) |
| AU (2) | AU2001268359B2 (pt) |
| BR (1) | BR0111627A (pt) |
| CA (1) | CA2410896A1 (pt) |
| DE (1) | DE60115460T2 (pt) |
| IL (1) | IL153175A0 (pt) |
| MX (1) | MXPA02012138A (pt) |
| NO (1) | NO20025851L (pt) |
| NZ (1) | NZ523572A (pt) |
| RU (1) | RU2003100535A (pt) |
| WO (1) | WO2001095716A2 (pt) |
| ZA (1) | ZA200209843B (pt) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA02011219A (es) * | 2000-05-18 | 2004-08-19 | Supachill Internat Pty Ltd | Metodo de enfriamiento para refrigeracion o congelacion a alta velocidad controlada. |
| MXPA03006063A (es) | 2001-01-02 | 2005-02-14 | Supachill Technologies Pty Ltd | Metodo y sistema para preparar muestras de tejidos para examenes histologicos y patologicos. |
| US6656380B2 (en) | 2001-10-16 | 2003-12-02 | Supachill Technologies Pty. Ltd. | Super-coolable composition having long-duration phase change capability, process for preparation of same, process for super-cooling same and articles comprising same |
| US11243494B2 (en) | 2002-07-31 | 2022-02-08 | Abs Global, Inc. | Multiple laminar flow-based particle and cellular separation with laser steering |
| US20050241333A1 (en) * | 2003-12-03 | 2005-11-03 | Hamilton Robert W | Rate-controlled freezer and cooling methods thereof |
| DK176397B1 (da) * | 2005-10-07 | 2007-11-26 | Gram Equipment As | Fremgangsmåde og styring af en termisk behandlingsenhed samt termisk behandlingsenhed |
| JP5100998B2 (ja) * | 2005-10-26 | 2012-12-19 | 国立大学法人広島大学 | 抜歯体の凍結保存方法 |
| US9159126B2 (en) | 2006-04-03 | 2015-10-13 | Jbs Usa, Llc | System and method for analyzing and processing food product |
| US7613330B2 (en) | 2006-04-03 | 2009-11-03 | Jbs Swift & Company | Methods and systems for tracking and managing livestock through the production process |
| US7606394B2 (en) * | 2006-04-03 | 2009-10-20 | Jbs Swift & Company | Methods and systems for administering a drug program related to livestock |
| US7892076B2 (en) | 2006-05-22 | 2011-02-22 | Swift & Company | Multibar apparatus and method for electrically stimulating a carcass |
| KR101467014B1 (ko) * | 2007-11-09 | 2014-12-01 | 프랙스에어 테크놀로지, 인코포레이티드 | 생물학적 물질의 프로그램 냉동을 위한 방법 및 시스템 |
| WO2009155430A2 (en) | 2008-06-18 | 2009-12-23 | The Cleveland Clinic Foundation | Systems and methods for vitrifying tissue |
| US9700038B2 (en) | 2009-02-25 | 2017-07-11 | Genea Limited | Cryopreservation of biological cells and tissues |
| CN103179852B (zh) | 2010-05-28 | 2015-04-08 | 格尼亚有限公司 | 改良的显微操作和储存装置以及方法 |
| US10908066B2 (en) | 2010-11-16 | 2021-02-02 | 1087 Systems, Inc. | Use of vibrational spectroscopy for microfluidic liquid measurement |
| JP6012164B2 (ja) * | 2011-11-25 | 2016-10-25 | 住友化学株式会社 | 多能性幹細胞由来の組織の凍結保存方法 |
| CN103416394A (zh) * | 2012-11-01 | 2013-12-04 | 上海理工大学 | 血管干燥保存的方法 |
| US8961904B2 (en) | 2013-07-16 | 2015-02-24 | Premium Genetics (Uk) Ltd. | Microfluidic chip |
| US11796449B2 (en) | 2013-10-30 | 2023-10-24 | Abs Global, Inc. | Microfluidic system and method with focused energy apparatus |
| JP2018509615A (ja) | 2015-02-19 | 2018-04-05 | プレミアム ジェネティクス （ユーケー） リミテッド | 走査型赤外線測定システム |
| EP3386297A1 (en) | 2015-12-07 | 2018-10-17 | CooperSurgical, Inc. | Low temperature specimen carriers and related methods |
| CN109642772B (zh) * | 2016-08-05 | 2022-06-24 | 巴克姆股份公司 | 干燥容器 |
| GB201621645D0 (en) | 2016-12-19 | 2017-02-01 | Asymptote Ltd | Shipping container |
| EP3796998A1 (en) | 2018-05-23 | 2021-03-31 | ABS Global, Inc. | Systems and methods for particle focusing in microchannels |
| FR3084991B1 (fr) | 2018-08-14 | 2020-11-06 | Cryocapcell | Dispositif de cryogenisation a commande hydraulique |
| EP3955735B1 (en) * | 2019-04-18 | 2024-05-22 | ABS Global, Inc. | System and process for continuous addition of cryoprotectant |
| US11628439B2 (en) | 2020-01-13 | 2023-04-18 | Abs Global, Inc. | Single-sheath microfluidic chip |
| US20240009295A1 (en) * | 2020-11-19 | 2024-01-11 | Upkara, Inc. | Ambient temperature lipid particle storage systems and methods |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1238618B (de) | 1959-11-09 | 1967-04-13 | Union Carbide Corp | Verfahren zur Konservierung biologischer Substanzen |
| US4429542A (en) * | 1981-08-10 | 1984-02-07 | Hoxan Corporation | Method of freezing fertilized ova, spermatozoa or the like and apparatus therefor |
| US4676070A (en) * | 1984-11-30 | 1987-06-30 | The Board Of Regents, The University Of Texas | Apparatus and method for cryopreparing biological tissue |
| US4848094A (en) * | 1988-04-29 | 1989-07-18 | Union Carbide Corporation | Droplet freezing method and apparatus |
| JPH02126075A (ja) * | 1988-11-01 | 1990-05-15 | Yuji Yamashita | 農水産物や加工食品類の急速冷凍装置 |
| US5029447A (en) | 1989-08-04 | 1991-07-09 | Cryo-Cell International Inc. | Multichamber storage apparatus and related method |
| ES2097152T3 (es) | 1989-08-22 | 1997-04-01 | Allan John Cassell | Aparato refrigerador. |
| US5003787A (en) | 1990-01-18 | 1991-04-02 | Savant Instruments | Cell preservation system |
| US5222367A (en) * | 1990-09-10 | 1993-06-29 | Technican Company, Ltd. | Method of freezing food utilizing a set agitator |
-
2000
- 2000-09-06 US US09/655,807 patent/US6519954B1/en not_active Expired - Fee Related
-
2001
- 2001-06-12 KR KR1020027016624A patent/KR20030034087A/ko not_active Application Discontinuation
- 2001-06-12 RU RU2003100535/15A patent/RU2003100535A/ru not_active Application Discontinuation
- 2001-06-12 AT AT01946288T patent/ATE311103T1/de not_active IP Right Cessation
- 2001-06-12 CA CA002410896A patent/CA2410896A1/en not_active Abandoned
- 2001-06-12 IL IL15317501A patent/IL153175A0/xx unknown
- 2001-06-12 AU AU2001268359A patent/AU2001268359B2/en not_active Ceased
- 2001-06-12 NZ NZ523572A patent/NZ523572A/en unknown
- 2001-06-12 AU AU6835901A patent/AU6835901A/xx active Pending
- 2001-06-12 MX MXPA02012138A patent/MXPA02012138A/es active IP Right Grant
- 2001-06-12 EP EP01946288A patent/EP1311153B1/en not_active Expired - Lifetime
- 2001-06-12 WO PCT/US2001/018916 patent/WO2001095716A2/en active IP Right Grant
- 2001-06-12 DE DE60115460T patent/DE60115460T2/de not_active Expired - Fee Related
- 2001-06-12 BR BR0111627-4A patent/BR0111627A/pt not_active IP Right Cessation
- 2001-06-12 CN CN01810856A patent/CN1434679A/zh active Pending
- 2001-06-12 JP JP2002509912A patent/JP2004503473A/ja not_active Withdrawn
-
2002
- 2002-12-04 ZA ZA200209843A patent/ZA200209843B/en unknown
- 2002-12-05 NO NO20025851A patent/NO20025851L/no not_active Application Discontinuation
- 2002-12-13 US US10/319,454 patent/US20030154729A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20030154729A1 (en) | 2003-08-21 |
| NO20025851D0 (no) | 2002-12-05 |
| AU6835901A (en) | 2001-12-24 |
| RU2003100535A (ru) | 2004-07-10 |
| KR20030034087A (ko) | 2003-05-01 |
| NO20025851L (no) | 2003-02-11 |
| CN1434679A (zh) | 2003-08-06 |
| US6519954B1 (en) | 2003-02-18 |
| AU2001268359B2 (en) | 2006-01-19 |
| DE60115460T2 (de) | 2006-08-24 |
| JP2004503473A (ja) | 2004-02-05 |
| CA2410896A1 (en) | 2001-12-20 |
| IL153175A0 (en) | 2003-06-24 |
| EP1311153A2 (en) | 2003-05-21 |
| EP1311153B1 (en) | 2005-11-30 |
| WO2001095716A3 (en) | 2002-05-23 |
| ZA200209843B (en) | 2004-07-05 |
| NZ523572A (en) | 2004-05-28 |
| ATE311103T1 (de) | 2005-12-15 |
| DE60115460D1 (de) | 2006-01-05 |
| MXPA02012138A (es) | 2004-08-19 |
| WO2001095716A2 (en) | 2001-12-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0111627A (pt) | Preservação criogênica de material biologicamente ativo usando congelamento de alta temperatura | |
| WO2002076203A3 (en) | Method and system for preparing tissue samples for histological and pathological examination | |
| SCHACHAR et al. | Investigations of low-temperature storage of articular cartilage for transplantation. | |
| Ozkavukcu et al. | Cryopreservation: basic knowledge and biophysical effects | |
| CN101088511B (zh) | 鱼类精子超低温冷冻保存简易方法 | |
| US20070042337A1 (en) | Isochoric method and device for reducing the probability of ice nucleation during preservation of biological matter at subzero centigrade temperatures | |
| AU2001268359A1 (en) | High temperature cryogenic preservation of biologically active material | |
| Storey et al. | Cryomicroscopic analysis of freezing in liver of the freeze-tolerant wood frog | |
| SHARMA et al. | Biophysics of cryopreservation | |
| CN105766892A (zh) | 一种利用重组光滑鳖甲抗冻蛋白对绵羊体外胚胎进行冷冻的方法 | |
| Miyamoto et al. | Solid CO2 freezing of mouse embryos | |
| Fahy | Vitrification of multicellular systems and whole organs | |
| Rajashekar | Supercooling characteristics of isolated peach flower bud primordia | |
| WO2008070412A2 (en) | Methods and compositions for reanimating cryopreserved oocytes | |
| Olar et al. | Effects of Thawing Rate and Cold Post-Thaw Temperatures on Bovine Semen Packaged in Glass Ampules | |
| EP1267613A2 (en) | Method and solutions for cryopreserving oocytes | |
| JP2005511756A (ja) | 冷却処理を行った保護剤を用いた低温保存のための生物試料の調製方法 | |
| Aussedat et al. | Organ preservation at low temperature: a physical and biological problem | |
| Gabdelfartovna et al. | Noncontact seeding | |
| Asahina et al. | Cryopreservation of sea urchin eggs | |
| Shaw et al. | Effect of warming procedures on slowly cooled mouse blastocysts | |
| Morris et al. | A novel approach to sperm freezing | |
| Chen et al. | Cryopreservation of human semen | |
| JPH0534953B2 (pt) | ||
| Fiser et al. | The effect of partial dehydration on the developmental capacity of mouse embryos stored in the supercooled state |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A , 9A E 10A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2112 DE 28/06/2011. |