BR0017067A - Inibidor de divisão de célula, desidrogenase, método para a produção de um inibidor de divisão de célula e composto - Google Patents

Inibidor de divisão de célula, desidrogenase, método para a produção de um inibidor de divisão de célula e composto

Info

Publication number
BR0017067A
BR0017067A BR0017067-4A BR0017067A BR0017067A BR 0017067 A BR0017067 A BR 0017067A BR 0017067 A BR0017067 A BR 0017067A BR 0017067 A BR0017067 A BR 0017067A
Authority
BR
Brazil
Prior art keywords
inhibitor
cell division
dehydrogenase
producing
compound
Prior art date
Application number
BR0017067-4A
Other languages
English (en)
Inventor
Kanzaki
Hiroshi
Kanoh
Kaneo
Yanagisawa Satohiro
Nitoda
Teruhiko
Akazawa
Kazumi
Original Assignee
Nereus Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nereus Pharmaceuticals Inc filed Critical Nereus Pharmaceuticals Inc
Publication of BR0017067A publication Critical patent/BR0017067A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

"INIBIDOR DE DIVISãO DE CéLULA, DESIDROGENASE, MéTODO PARA A PRODUçãO DE UM INIBIDOR DE DIVISãO DE CéLULA E COMPOSTO". A presente invenção se refere a um inibidor de divisão de célula o qual compreende diversas dehidrodiceto piperazinas tais como dehidrofenilaistina, ou análogos da mesma como o ingrediente ativo, e uma desidrogenase e a um método para a produção do mesmo inibidor.
BR0017067-4A 2000-01-18 2000-09-29 Inibidor de divisão de célula, desidrogenase, método para a produção de um inibidor de divisão de célula e composto BR0017067A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000009370 2000-01-18
PCT/JP2000/006807 WO2001053290A1 (fr) 2000-01-18 2000-09-29 Inhibiteurs de la division cellulaire et procede de production de ces inhibiteurs

Publications (1)

Publication Number Publication Date
BR0017067A true BR0017067A (pt) 2002-10-22

Family

ID=18537534

Family Applications (2)

Application Number Title Priority Date Filing Date
BR0017067-4A BR0017067A (pt) 2000-01-18 2000-09-29 Inibidor de divisão de célula, desidrogenase, método para a produção de um inibidor de divisão de célula e composto
BRPI0017067A BRPI0017067B8 (pt) 2000-01-18 2000-09-29 inibidor de divisão de célula, desidrogenase, método para a produção de um inibidor de divisão de célula e composto

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI0017067A BRPI0017067B8 (pt) 2000-01-18 2000-09-29 inibidor de divisão de célula, desidrogenase, método para a produção de um inibidor de divisão de célula e composto

Country Status (12)

Country Link
US (2) US6972289B1 (pt)
EP (1) EP1264831A4 (pt)
JP (1) JP4810043B2 (pt)
KR (1) KR100831400B1 (pt)
AU (2) AU782917C (pt)
BR (2) BR0017067A (pt)
CA (1) CA2403790C (pt)
IL (2) IL150430A0 (pt)
MX (1) MXPA02006826A (pt)
NZ (1) NZ519989A (pt)
WO (1) WO2001053290A1 (pt)
ZA (1) ZA200206576B (pt)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2545066T3 (es) 1997-06-09 2015-09-08 Hitachi, Ltd. Medio de grabación de información de imágenes
US7026322B2 (en) 1998-11-12 2006-04-11 Nereus Pharmaceuticals, Inc. Phenylahistin and the phenylahistin analogs, a new class of anti-tumor compounds
EP1264831A4 (en) * 2000-01-18 2005-11-23 Nereus Pharmaceuticals Inc Cell division inhibitors and a method for fixing the same
PT1529044E (pt) * 2002-08-02 2008-01-14 Nereus Pharmaceuticals Inc Desidrofenila-histinas e os seus análogos e a síntese de desidrofenila-histinas e os seus análogos
US7919497B2 (en) 2002-08-02 2011-04-05 Nereus Pharmaceuticals, Inc. Analogs of dehydrophenylahistins and their therapeutic use
CN101633655B (zh) * 2002-08-02 2014-04-30 大连万春药业有限公司 脱氢苯基阿夕斯丁及其类似物以及脱氢苯基阿夕斯丁及其类似物的合成
US7935704B2 (en) 2003-08-01 2011-05-03 Nereus Pharmaceuticals, Inc. Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof
PL377686A1 (pl) * 2002-12-18 2006-02-06 Pfizer Products Inc. Pochodne 4-anilinochinazoliny do leczenia anormalnego wzrostu komórek
GR1004602B (el) 2003-07-03 2004-06-18 Μεθοδοι παρασκευης παραγωγων δεϋδρο-δικετοπιπεραζινων
WO2005077940A1 (en) * 2004-02-04 2005-08-25 Nereus Pharmaceuticals, Inc. Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof
CN1934101B (zh) * 2004-02-04 2011-10-12 尼瑞斯药品公司 脱氢苯基阿夕斯丁及其类似物以及脱氢苯基阿夕斯丁及其类似物的合成
US7732605B2 (en) * 2005-03-29 2010-06-08 Nereus Pharmaceuticals, Inc. Synthesis of diketopiperazines
AR058408A1 (es) 2006-01-02 2008-01-30 Basf Ag Compuestos de piperazina con accion herbicida
DE502007003395D1 (de) * 2006-01-05 2010-05-20 Basf Se Piperazinverbindungen mit herbizider wirkung
US8129527B2 (en) 2006-11-03 2012-03-06 Nereus Pharmacuticals, Inc. Analogs of dehydrophenylahistins and their therapeutic use
EA200901659A1 (ru) * 2007-06-12 2010-06-30 Басф Се Соединения пиперазина с гербицидным действием
WO2008152074A1 (de) * 2007-06-12 2008-12-18 Basf Se Herbizid wirksame zusammensetzung
EP2054395A2 (de) * 2007-06-12 2009-05-06 Basf Se Piperazinverbindungen mit herbizider wirkung
BRPI0916684A2 (pt) * 2008-07-29 2015-08-04 Basf Se Compostos de piperazina, composição, e, processo para combater vegetação indesejada
CN102119153A (zh) * 2008-08-13 2011-07-06 巴斯夫欧洲公司 制备哌嗪二酮衍生物的方法
BRPI0919576A2 (pt) * 2008-10-02 2015-08-18 Basf Se Composto de piperazina, e, método para controlar vegetação indesejada
RU2728796C2 (ru) 2015-03-06 2020-07-31 Бейондспринг Фармасьютикалс, Инк. Способ лечения опухоли головного мозга
MY190034A (en) 2015-03-06 2022-03-22 Beyondspring Pharmaceuticals Inc Method of treating cancer associated with a ras mutation
PE20180528A1 (es) 2015-07-13 2018-03-19 Beyondspring Pharmaceuticals Inc Composiciones de plinabulina
MX2018009413A (es) 2016-02-08 2019-05-15 Beyondspring Pharmaceuticals Inc Composiciones que contienen tucaresol o sus analogos.
TWI777957B (zh) 2016-06-06 2022-09-21 中國大陸商大連萬春布林醫藥有限公司 降低嗜中性白血球減少症之組合物及方法
CN109563079B (zh) 2016-08-12 2021-10-26 深圳华大海洋科技有限公司 脱氢苯基阿夕斯丁类化合物的多晶型及其制备纯化方法和应用
CN106565686B (zh) * 2016-10-11 2019-03-01 深圳海王医药科技研究院有限公司 微管蛋白抑制剂
EP3565812B1 (en) 2017-01-06 2023-12-27 Beyondspring Pharmaceuticals, Inc. Tubulin binding compounds and therapeutic use thereof
BR112019015974A2 (pt) 2017-02-01 2020-03-31 Beyondspring Pharmaceuticals, Inc. Método para reduzir neutropenia
KR20200112881A (ko) 2018-01-24 2020-10-05 비욘드스프링 파마수티컬스, 인코포레이티드. 플리나불린의 투여를 통해 혈소판감소증을 감소시키는 조성물 및 방법
KR20220117501A (ko) 2021-02-17 2022-08-24 주식회사 티제이 카드리더기 모듈의 슬림화장치

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0725858A (ja) 1993-07-13 1995-01-27 Otsuka Pharmaceut Co Ltd ピペラジン誘導体
GB9402809D0 (en) * 1994-02-14 1994-04-06 Xenova Ltd Pharmaceutical compounds
GB9402807D0 (en) * 1994-02-14 1994-04-06 Xenova Ltd Pharmaceutical compounds
GB9426224D0 (en) * 1994-12-23 1995-02-22 Xenova Ltd Pharmaceutical compounds
JP3131574B2 (ja) * 1996-09-04 2001-02-05 新日本製鐵株式会社 新規抗腫瘍物質、該物質を製造するための微生物及び方法、並びに該物質を有効成分とする細胞周期阻害剤及び抗腫瘍剤
US6069146A (en) * 1998-03-25 2000-05-30 The Regents Of The University Of California Halimide, a cytotoxic marine natural product, and derivatives thereof
US6358957B1 (en) * 1998-11-12 2002-03-19 Nereus Pharmaceuticals, Inc. Phenylahistin and the phenylahistin analogs, a new class of anti-tumor compounds
EP1264831A4 (en) * 2000-01-18 2005-11-23 Nereus Pharmaceuticals Inc Cell division inhibitors and a method for fixing the same
PT1529044E (pt) * 2002-08-02 2008-01-14 Nereus Pharmaceuticals Inc Desidrofenila-histinas e os seus análogos e a síntese de desidrofenila-histinas e os seus análogos
US7919497B2 (en) * 2002-08-02 2011-04-05 Nereus Pharmaceuticals, Inc. Analogs of dehydrophenylahistins and their therapeutic use

Also Published As

Publication number Publication date
EP1264831A1 (en) 2002-12-11
AU782917C (en) 2006-11-23
IL150430A (en) 2011-03-31
CA2403790C (en) 2011-09-27
BRPI0017067B8 (pt) 2021-05-25
BRPI0017067B1 (pt) 2019-08-27
WO2001053290A1 (fr) 2001-07-26
AU782917B2 (en) 2005-09-08
KR100831400B1 (ko) 2008-05-21
EP1264831A4 (en) 2005-11-23
ZA200206576B (en) 2003-05-12
NZ519989A (en) 2004-05-28
AU2005242133A1 (en) 2006-01-05
MXPA02006826A (es) 2004-04-05
CA2403790A1 (en) 2001-07-26
JP4810043B2 (ja) 2011-11-09
IL150430A0 (en) 2002-12-01
AU2005242133B2 (en) 2009-09-03
KR20020082484A (ko) 2002-10-31
US6972289B1 (en) 2005-12-06
AU7451100A (en) 2001-07-31
US20060079534A1 (en) 2006-04-13

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Legal Events

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B25A Requested transfer of rights approved

Owner name: DALIAN WANCHUN BIOTECHNOLOGY CO., LTD. (CN)

B25A Requested transfer of rights approved

Owner name: BEYONDSPRING PHARMACEUTICALS, INC (US)

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