BR0016161A - Mistura de oligossacarìdeos - Google Patents
Mistura de oligossacarìdeosInfo
- Publication number
- BR0016161A BR0016161A BR0016161-6A BR0016161A BR0016161A BR 0016161 A BR0016161 A BR 0016161A BR 0016161 A BR0016161 A BR 0016161A BR 0016161 A BR0016161 A BR 0016161A
- Authority
- BR
- Brazil
- Prior art keywords
- oligosaccharides
- mixture
- animal
- milks
- milk
- Prior art date
Links
- 229920001542 oligosaccharide Polymers 0.000 title abstract 17
- 150000002482 oligosaccharides Chemical class 0.000 title abstract 17
- 239000000203 mixture Substances 0.000 title abstract 7
- 235000020244 animal milk Nutrition 0.000 abstract 6
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000002924 anti-infective effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 235000020256 human milk Nutrition 0.000 abstract 1
- 210000004251 human milk Anatomy 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
- 150000002772 monosaccharides Chemical group 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 230000008092 positive effect Effects 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/20—Milk; Whey; Colostrum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Nutrition Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Fodder In General (AREA)
- Materials For Medical Uses (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Macromonomer-Based Addition Polymer (AREA)
Abstract
"MISTURA DE OLIGOSSACARìDEOS". é preparada uma mistura de oligossacarídeos à base de oligossacarídeos, que foram obtidos a partir de um ou mais leites animais e que são compostos de duas ou mais unidades de monossacarídeos. Esta mistura de oligossacarídeos caracteriza-se pelo fato de que ela apresenta pelo menos duas frações de oligossacarídeos, que são estruturados em cada caso de pelo menos dois oligossacarídeos diferentes, sendo que lactose livre não pertence a eles, de que o espectro total dos oligossacarídeos presentes na mistura de oligossacarídeos diferencia-se daquele do leite animal ou dos leites animais, dos quais as frações de oligossacarídeos foram obtidas, e que, a) desde que os oligossacarídeos sejam obtidos de apenas um leite animal, a proporção de oligossacarídeos neutros para oligossacarídeos ácidos perfaz 90 - 60:10 - 40 % em peso, ou b) desde que os oligossacarídeos sejam obtidos de pelo menos dois leites animais, os oligossacarídeos obtidos de dois leites animais diferentes perfazem em cada caso pelo menos 10% em peso dos oligossacarídeos presentes no total na mistura dos oligossacarídeos. A mistura de oligossacarídeos de acordo com a invenção, em relação ao seu efeito positivo e particularmente seu efeito antiinfeccioso, é semelhante àquele de leite humano.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19958985A DE19958985A1 (de) | 1999-12-07 | 1999-12-07 | Oligosaccharidmischung |
PCT/EP2000/012345 WO2001042263A2 (de) | 1999-12-07 | 2000-12-07 | Oligosaccharidmischung |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0016161A true BR0016161A (pt) | 2002-10-29 |
Family
ID=7931729
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0016161-6A BR0016161A (pt) | 1999-12-07 | 2000-12-07 | Mistura de oligossacarìdeos |
Country Status (20)
Country | Link |
---|---|
US (1) | US7939118B2 (pt) |
EP (1) | EP1242436B1 (pt) |
JP (1) | JP2003516412A (pt) |
CN (1) | CN1198624C (pt) |
AT (1) | ATE282626T1 (pt) |
AU (1) | AU782623B2 (pt) |
BR (1) | BR0016161A (pt) |
CA (1) | CA2394090C (pt) |
CZ (1) | CZ304817B6 (pt) |
DE (2) | DE19958985A1 (pt) |
DK (1) | DK1242436T3 (pt) |
ES (1) | ES2233485T3 (pt) |
HK (1) | HK1052438B (pt) |
HU (1) | HUP0203707A3 (pt) |
MX (1) | MXPA02005491A (pt) |
NO (1) | NO330050B1 (pt) |
NZ (1) | NZ519706A (pt) |
PL (1) | PL356238A1 (pt) |
PT (1) | PT1242436E (pt) |
WO (1) | WO2001042263A2 (pt) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1243273A1 (en) * | 2001-03-22 | 2002-09-25 | Societe Des Produits Nestle S.A. | Composition comprising a prebiotic for decreasing infammatory process and abnormal activation of non-specific immune parameters |
NZ515869A (en) * | 2001-11-30 | 2003-09-26 | Med Chem Ingredients Ltd | Compositions and methods for animal treatment comprising gluco- and isomalto- oligosaccharides |
AU2005274824A1 (en) | 2004-07-19 | 2006-02-23 | Life Science Nutrition As | NGNA compositions and methods of use |
US20080126195A1 (en) | 2004-07-22 | 2008-05-29 | Ritter Andrew J | Methods and Compositions for Treating Lactose Intolerance |
EP1634599A1 (en) | 2004-08-20 | 2006-03-15 | N.V. Nutricia | Iimmune stimulatory infant nutrition |
US8591981B2 (en) * | 2005-02-21 | 2013-11-26 | Nestec S.A. | Oligosaccharide mixture |
US7572474B2 (en) | 2005-06-01 | 2009-08-11 | Mead Johnson Nutrition Company | Method for simulating the functional attributes of human milk oligosaccharides in formula-fed infants |
US8287931B2 (en) | 2005-06-30 | 2012-10-16 | Mead Johnson Nutrition Company | Nutritional composition to promote healthy development and growth |
US8075934B2 (en) * | 2008-10-24 | 2011-12-13 | Mead Johnson Nutrition Company | Nutritional composition with improved digestibility |
EP1776877A1 (en) * | 2005-10-21 | 2007-04-25 | N.V. Nutricia | Method for stimulating the intestinal flora |
PL1988786T3 (pl) * | 2006-02-10 | 2010-10-29 | Nestec Sa | Mieszanka oligosacharydowa |
RU2448720C2 (ru) | 2006-03-07 | 2012-04-27 | Нестек С.А. | Синбиотическая смесь |
WO2007114683A1 (en) * | 2006-03-30 | 2007-10-11 | N.V. Nutricia | Milk oligosaccharides for stimulating the immune system |
EP1974743A1 (en) * | 2007-03-28 | 2008-10-01 | Nestec S.A. | Probiotics to Improve Gut Microbiota |
NZ581390A (en) * | 2007-06-25 | 2012-09-28 | Dsm Ip Assets Bv | Prebiotics comprising an oligosaccharide, sialyloligosaccharide and free sialic acid |
SG185948A1 (en) * | 2007-11-08 | 2012-12-28 | Nestec Sa | Use of oligosaccharides containing n-acetyllactosamine for maturation of immune responses in neonates |
EP2143341A1 (en) | 2008-07-08 | 2010-01-13 | Nestec S.A. | Nutritional Composition Containing Oligosaccharide Mixture |
US8986769B2 (en) * | 2008-10-24 | 2015-03-24 | Mead Johnson Nutrition Company | Methods for preserving endogenous TGF-β |
WO2010052575A2 (en) | 2008-11-10 | 2010-05-14 | Scandivir Ab | Ngna compositions and methods of use |
US8927027B2 (en) * | 2008-12-02 | 2015-01-06 | Prolacta Bioscience | Human milk permeate compositions and methods of making and using same |
US8425955B2 (en) | 2009-02-12 | 2013-04-23 | Mead Johnson Nutrition Company | Nutritional composition with prebiotic component |
CN102404990A (zh) | 2009-02-24 | 2012-04-04 | 里特制药股份有限公司 | 益生素制剂和使用方法 |
US8293264B2 (en) * | 2009-05-11 | 2012-10-23 | Mead Johnson Nutrition Company | Nutritional composition to promote healthy development and growth |
WO2011137249A1 (en) | 2010-04-28 | 2011-11-03 | Ritter Pharmaceuticals, Inc. | Prebiotic formulations and methods of use |
EP2455387A1 (en) * | 2010-11-23 | 2012-05-23 | Nestec S.A. | Oligosaccharide mixture and food product comprising this mixture, especially infant formula |
CN110051676A (zh) | 2010-12-31 | 2019-07-26 | 雅培制药有限公司 | 用于调节炎症的人乳寡糖 |
NZ611807A (en) | 2010-12-31 | 2015-02-27 | Abbott Lab | Methods for decreasing the incidence of necrotizing enterocolitis in infants, toddlers, or children using human milk oligosaccharides |
MX355780B (es) | 2010-12-31 | 2018-04-30 | Abbott Lab | Fórmula pediátrica sintética para estimular células nerviosas entéricas en el tracto gastrointestinal. |
CA2822497C (en) | 2010-12-31 | 2020-07-28 | Abbott Laboratories | Methods for reducing the incidence of oxidative stress using human milk oligosaccharides, vitamin c and anti-inflammatory agents |
EP3473257A1 (en) | 2010-12-31 | 2019-04-24 | Abbott Laboratories | Methods of using human milk oligosaccharides for improving airway respiratory health |
EP3510873A1 (en) | 2010-12-31 | 2019-07-17 | Abbott Laboratories | Nutritional compositions comprising human milk oligosaccharides and nucleotides and uses thereof for treating and/or preventing enteric viral infection |
MX352040B (es) | 2010-12-31 | 2017-11-07 | Abbott Lab | Formulaciones nutricionales que incluyen los oligosacaridos de leche humana y los acidos grasos poliinsaturados de cadena larga y usos de las mismas. |
CA2835057C (en) * | 2011-05-05 | 2016-07-19 | Life Science Nutrition As | Performance enhancing compositions and methods of use |
EP2526784A1 (en) | 2011-05-24 | 2012-11-28 | Nestec S.A. | Milk oligosaccharide-galactooligosaccharide composition for infant formula containing the soluble oligosaccharide fraction present in milk, and having a low level of monosaccharides, and a process to produce the composition |
BR112014004772A2 (pt) | 2011-08-29 | 2017-03-21 | Abbott Lab | oligossacarídeos do leite humano para evitar danos e/ou promover a cura do trato gastrointestinal |
AU2014368585A1 (en) * | 2013-12-19 | 2016-05-19 | Nestec S.A. | Nutritional composition for use in reducing metabolic stress in infants, decreasing gut permeability and approximating growth rate of breast-fed infants |
CN106659226A (zh) | 2014-08-18 | 2017-05-10 | 雀巢产品技术援助有限公司 | 用于降低以后生命中肥胖风险的益生元 |
JP6058223B2 (ja) * | 2015-01-20 | 2017-01-11 | 株式会社明治 | リン吸収抑制用組成物 |
ES2971093T3 (es) * | 2015-03-31 | 2024-06-03 | Glycom As | Mezclas de oligosacáridos de la leche humana que comprenden 3'-O-sialilactosa |
US10933097B1 (en) | 2020-03-05 | 2021-03-02 | King Saud University | Method of treating a bacterial infection using colostrum |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4859488A (en) * | 1987-09-15 | 1989-08-22 | Kabushiki Kaisha Yakult Honsha | Liquid food for curing constipation: polydextrose and oligosaccharide |
JP2518663B2 (ja) * | 1987-12-24 | 1996-07-24 | 株式会社ヤクルト本社 | ガラクトオリゴ糖含有加工乳の製造法 |
US5750176A (en) * | 1994-03-09 | 1998-05-12 | Abbott Laboratories | Transgenic non-human mammal milk comprising 2'-fucosyl-lactose |
DE19701382A1 (de) | 1997-01-16 | 1998-07-23 | Nutricia Nv | Kohlenhydratmischung |
US6045854A (en) * | 1997-03-31 | 2000-04-04 | Abbott Laboraties | Nutritional formulations containing oligosaccharides |
-
1999
- 1999-12-07 DE DE19958985A patent/DE19958985A1/de not_active Ceased
-
2000
- 2000-12-07 PT PT00983244T patent/PT1242436E/pt unknown
- 2000-12-07 CZ CZ2002-1876A patent/CZ304817B6/cs not_active IP Right Cessation
- 2000-12-07 US US10/148,193 patent/US7939118B2/en not_active Expired - Fee Related
- 2000-12-07 CA CA2394090A patent/CA2394090C/en not_active Expired - Fee Related
- 2000-12-07 PL PL00356238A patent/PL356238A1/xx not_active Application Discontinuation
- 2000-12-07 MX MXPA02005491A patent/MXPA02005491A/es active IP Right Grant
- 2000-12-07 DK DK00983244T patent/DK1242436T3/da active
- 2000-12-07 NZ NZ519706A patent/NZ519706A/en not_active IP Right Cessation
- 2000-12-07 BR BR0016161-6A patent/BR0016161A/pt not_active Application Discontinuation
- 2000-12-07 JP JP2001543560A patent/JP2003516412A/ja active Pending
- 2000-12-07 ES ES00983244T patent/ES2233485T3/es not_active Expired - Lifetime
- 2000-12-07 CN CNB008168121A patent/CN1198624C/zh not_active Expired - Fee Related
- 2000-12-07 HU HU0203707A patent/HUP0203707A3/hu not_active Application Discontinuation
- 2000-12-07 AT AT00983244T patent/ATE282626T1/de active
- 2000-12-07 EP EP00983244A patent/EP1242436B1/de not_active Revoked
- 2000-12-07 WO PCT/EP2000/012345 patent/WO2001042263A2/de active IP Right Grant
- 2000-12-07 AU AU20062/01A patent/AU782623B2/en not_active Ceased
- 2000-12-07 DE DE50008706T patent/DE50008706D1/de not_active Expired - Lifetime
-
2002
- 2002-06-06 NO NO20022688A patent/NO330050B1/no not_active IP Right Cessation
-
2003
- 2003-07-05 HK HK03104777.8A patent/HK1052438B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NO20022688L (no) | 2002-06-06 |
NO330050B1 (no) | 2011-02-07 |
WO2001042263A3 (de) | 2001-11-01 |
AU2006201A (en) | 2001-06-18 |
ES2233485T3 (es) | 2005-06-16 |
HK1052438B (zh) | 2005-07-08 |
PL356238A1 (en) | 2004-06-28 |
CN1198624C (zh) | 2005-04-27 |
ATE282626T1 (de) | 2004-12-15 |
DE50008706D1 (en) | 2004-12-23 |
CA2394090C (en) | 2010-09-28 |
WO2001042263A2 (de) | 2001-06-14 |
HUP0203707A2 (hu) | 2003-03-28 |
EP1242436B1 (de) | 2004-11-17 |
NO20022688D0 (no) | 2002-06-06 |
CZ304817B6 (cs) | 2014-11-12 |
US20030129278A1 (en) | 2003-07-10 |
AU782623B2 (en) | 2005-08-18 |
JP2003516412A (ja) | 2003-05-13 |
DK1242436T3 (da) | 2005-03-14 |
NZ519706A (en) | 2004-03-26 |
CA2394090A1 (en) | 2001-06-14 |
PT1242436E (pt) | 2005-04-29 |
DE19958985A1 (de) | 2001-06-13 |
US7939118B2 (en) | 2011-05-10 |
CZ20021876A3 (cs) | 2003-05-14 |
EP1242436A2 (de) | 2002-09-25 |
CN1407857A (zh) | 2003-04-02 |
HUP0203707A3 (en) | 2004-12-28 |
MXPA02005491A (es) | 2002-09-02 |
HK1052438A1 (en) | 2003-09-19 |
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Legal Events
Date | Code | Title | Description |
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
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