BR0012981A - Sistema para liberação oral de droga hidrodinamicamente balanceado - Google Patents
Sistema para liberação oral de droga hidrodinamicamente balanceadoInfo
- Publication number
- BR0012981A BR0012981A BR0012981-0A BR0012981A BR0012981A BR 0012981 A BR0012981 A BR 0012981A BR 0012981 A BR0012981 A BR 0012981A BR 0012981 A BR0012981 A BR 0012981A
- Authority
- BR
- Brazil
- Prior art keywords
- drug
- release system
- drug release
- oral drug
- time
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"SISTEMA PARA LIBERAçãO ORAL DE DROGA HIDRODINAMICAMENTE BALANCEADO". A presente invenção refere-se a um sistema gastro-retentor de liberação oral de droga compreendendo uma matriz de elevada porosidade e, pelo menos, uma droga, açúcar(es) , componentes geradores de gás e, opcionalmente, componentes auxiliares farmaceuticamente aceitáveis. A composição farmacêutica, seja sob a forma de pílulas (forma de dosagem multiparticulada ou unitária), glóbulos, grânulos ou cápsulas é retida no estómago, enquanto a droga é seletivamente liberada a nível gástrico e em partes superiores do intestino delgado por um longo período de tempo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IB1999/001386 WO2001010405A1 (en) | 1999-08-04 | 1999-08-04 | Hydrodynamically balanced oral drug delivery system |
PCT/IB2000/001083 WO2001010419A1 (en) | 1999-08-04 | 2000-08-01 | Hydrodynamically balancing oral drug delivery system |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0012981A true BR0012981A (pt) | 2002-06-18 |
Family
ID=11004886
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0012981-0A BR0012981A (pt) | 1999-08-04 | 2000-08-01 | Sistema para liberação oral de droga hidrodinamicamente balanceado |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP1206249A4 (pt) |
JP (1) | JP2003506400A (pt) |
CN (1) | CN1376059A (pt) |
AP (1) | AP2002002410A0 (pt) |
AU (2) | AU5060499A (pt) |
BR (1) | BR0012981A (pt) |
CA (1) | CA2378468A1 (pt) |
CZ (1) | CZ2002415A3 (pt) |
EA (1) | EA200200126A1 (pt) |
HK (1) | HK1047226A1 (pt) |
HR (1) | HRP20020108A2 (pt) |
HU (1) | HUP0202497A3 (pt) |
IL (1) | IL147966A0 (pt) |
MX (1) | MXPA02001272A (pt) |
NZ (1) | NZ516959A (pt) |
OA (1) | OA12003A (pt) |
PL (1) | PL353321A1 (pt) |
SK (1) | SK1832002A3 (pt) |
TR (1) | TR200200467T2 (pt) |
WO (2) | WO2001010405A1 (pt) |
ZA (1) | ZA200200926B (pt) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100457458B1 (ko) * | 2001-04-02 | 2004-11-17 | 삼아약품 주식회사 | 속용정 및 그의 제조방법 |
EP1411901B1 (en) | 2001-07-04 | 2010-08-18 | Sun Pharma Advanced Research Company Ltd | Gastric retention controlled drug delivery system |
CA2466032A1 (en) * | 2001-10-29 | 2003-05-08 | Laure Patricia Ouadji Njiki | Methods and dosage forms for improving the bioavailability of therapeutic agents |
US20050226926A1 (en) | 2002-07-25 | 2005-10-13 | Pfizer Inc | Sustained-release tablet composition of pramipexole |
KR20060083198A (ko) * | 2003-08-27 | 2006-07-20 | 벡타 리미티드 | 위산 분비의 억제를 필요로하는 병상의 치료를 위한 조성물 |
TW200533391A (en) * | 2004-03-25 | 2005-10-16 | Sun Pharmaceutical Ind Ltd | Gastric retention drug delivery system |
PL1789021T3 (pl) | 2004-08-13 | 2012-04-30 | Boehringer Ingelheim Int | Preparat tabletkowy o przedłużonym uwalnianiu zawierający pramipeksol lub jego farmaceutycznie dopuszczalną sól |
DE102004042139B4 (de) * | 2004-08-31 | 2009-06-10 | Aristocon Verwaltungs- Gmbh | Perorale Darreichungsformen zur Erzielung eines Retardierungseffektes nach der Arzneimitteleinnahme mit einer Mahlzeit |
EP1690540A1 (en) * | 2005-02-15 | 2006-08-16 | Neuro3D | Composition comprising ocaperidone |
EP1962586B1 (en) | 2005-12-22 | 2017-07-12 | Oakwood Laboratories L.L.C. | Sublimable sustained release delivery system and method of making same |
EP1886665A1 (en) * | 2006-08-01 | 2008-02-13 | Boehringer Ingelheim Pharma GmbH & Co. KG | Gastro retentive delivery system |
EP2144599B1 (en) | 2007-03-02 | 2010-08-04 | Farnam Companies, Inc. | Sustained release pellets comprising wax-like material |
WO2010020098A1 (zh) | 2008-08-18 | 2010-02-25 | 北京天衡药物研究院 | 胃滞留药物释出系统及其制备方法和用途 |
CA2733787C (en) | 2008-08-15 | 2016-09-06 | Depomed, Inc. | Gastric retentive pharmaceutical compositions for treatment and prevention of cns disorders |
US9622977B2 (en) | 2008-10-08 | 2017-04-18 | Bioplus Life Sciences Pvt, Ltd. | Sustained release drug delivery system |
EP2283824B1 (en) | 2009-07-30 | 2017-04-19 | Special Products Line S.p.A. | Compositions and formulations based on swellable matrices for sustained release of poorly soluble drugs such as clarithromycin |
JP2013103879A (ja) * | 2011-11-10 | 2013-05-30 | Nakanihon Capsule Co Ltd | ハードカプセル |
KR102241487B1 (ko) | 2013-02-20 | 2021-04-16 | 주식회사 종근당 | 제어방출 펠릿으로 된 약제학적 조성물 |
AU2014228861B2 (en) * | 2013-03-15 | 2018-05-24 | Aprecia Pharmaceuticals LLC | Rapidly dispersible dosage form of topiramate |
CN103462917A (zh) * | 2013-09-12 | 2013-12-25 | 南京正宽医药科技有限公司 | 一种用于抗病毒的阿昔洛韦片剂及其制备方法 |
MX2018015588A (es) * | 2016-06-14 | 2019-04-11 | Prevtec Microbia Inc | Pellets de alimento animal que incluyen un aditivo alimenticio, metodo para hacerlos y usarlos. |
DK3648747T3 (da) | 2017-06-16 | 2022-11-28 | Amneal Complex Products Res Llc | Gastroretentive doseringsformer til vedvarende frigivelse af lægemidler |
US10987311B2 (en) | 2017-06-16 | 2021-04-27 | Kashiv Specialty Pharmaceuticals, Llc | Extended release compositions comprising pyridostigmine |
US10588863B2 (en) | 2017-06-16 | 2020-03-17 | Kashiv Biosciences, Llc | Extended release compositions comprising pyridostigmine |
CN107375287B (zh) * | 2017-08-22 | 2019-11-29 | 安徽省肿瘤医院 | 一种硫酸阿托品在制备治疗原发性肝癌药物中的用途 |
CN107349195A (zh) * | 2017-08-22 | 2017-11-17 | 安徽省肿瘤医院 | 一种维拉帕米在制备治疗转移性肝癌药物中的用途 |
CN107441115A (zh) * | 2017-08-22 | 2017-12-08 | 安徽省肿瘤医院 | 一种维拉帕米联合碳酸氢钠在制备原发性肝癌治疗药物中的用途 |
DK3824881T3 (da) | 2018-06-18 | 2022-05-09 | Amneal Complex Products Res Llc | Sammensætning omfattende pyridostigminbromid med forlænget frigivelse |
CA3065695C (en) | 2018-06-27 | 2021-06-01 | Kashiv Biosciences, Llc | Self-regulating osmotic gastroretentive drug delivery systems |
WO2020230089A1 (en) | 2019-05-14 | 2020-11-19 | Clexio Biosciences Ltd. | Treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease |
WO2022195476A1 (en) | 2021-03-15 | 2022-09-22 | Clexio Biosciences Ltd. | Gastroretentive devices for assessment of intragastric conditions |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH675537A5 (pt) * | 1988-03-25 | 1990-10-15 | Ciba Geigy Ag | |
US5096714A (en) * | 1988-06-28 | 1992-03-17 | Hauser-Kuhrts, Inc. | Prolonged release drug tablet formulations |
DE69017915T2 (de) * | 1989-10-26 | 1995-07-27 | Nippon Shinyaku Co Ltd | Zubereitung für den magen. |
MX9300110A (es) * | 1992-01-13 | 1994-07-29 | Gerhard Gergely | Preparacion farmaceutica en la forma de una tableta de efervescencia o de desintegracion o de un granulado de tipo instanteneo y procedimiento para su preparacion. |
GB9322314D0 (en) * | 1993-10-29 | 1993-12-15 | Scherer Ltd R P | Foam generating capsules |
DE4403943A1 (de) * | 1994-02-08 | 1995-08-10 | Hexal Pharma Gmbh | Orale Azrneimittelzubereitung mit Diclofenac-Natrium |
GB9418530D0 (en) * | 1994-09-14 | 1994-11-02 | Glaxo Group Ltd | Medicaments |
US5788987A (en) * | 1997-01-29 | 1998-08-04 | Poli Industria Chimica Spa | Methods for treating early morning pathologies |
IT1293764B1 (it) * | 1997-07-23 | 1999-03-10 | Chiesi Farma Spa | Composizioni farmaceutiche sotto forma di compresse effervescenti contenenti un principio attivo instabile in presenza di acqua |
-
1999
- 1999-08-04 WO PCT/IB1999/001386 patent/WO2001010405A1/en active Application Filing
- 1999-08-04 AU AU50604/99A patent/AU5060499A/en not_active Abandoned
- 1999-08-04 AP APAP/P/2002/002410A patent/AP2002002410A0/en unknown
-
2000
- 2000-08-01 HU HU0202497A patent/HUP0202497A3/hu unknown
- 2000-08-01 AU AU63099/00A patent/AU774957B2/en not_active Ceased
- 2000-08-01 WO PCT/IB2000/001083 patent/WO2001010419A1/en not_active Application Discontinuation
- 2000-08-01 BR BR0012981-0A patent/BR0012981A/pt not_active IP Right Cessation
- 2000-08-01 PL PL00353321A patent/PL353321A1/xx not_active Application Discontinuation
- 2000-08-01 SK SK183-2002A patent/SK1832002A3/sk unknown
- 2000-08-01 EA EA200200126A patent/EA200200126A1/ru unknown
- 2000-08-01 OA OA1200200041A patent/OA12003A/en unknown
- 2000-08-01 NZ NZ516959A patent/NZ516959A/en unknown
- 2000-08-01 CN CN00813344A patent/CN1376059A/zh active Pending
- 2000-08-01 MX MXPA02001272A patent/MXPA02001272A/es not_active Application Discontinuation
- 2000-08-01 CZ CZ2002415A patent/CZ2002415A3/cs unknown
- 2000-08-01 JP JP2001514939A patent/JP2003506400A/ja active Pending
- 2000-08-01 CA CA002378468A patent/CA2378468A1/en not_active Abandoned
- 2000-08-01 EP EP00949840A patent/EP1206249A4/en not_active Withdrawn
- 2000-08-01 IL IL14796600A patent/IL147966A0/xx unknown
- 2000-08-01 TR TR2002/00467T patent/TR200200467T2/xx unknown
-
2002
- 2002-02-01 ZA ZA200200926A patent/ZA200200926B/en unknown
- 2002-02-04 HR HR20020108A patent/HRP20020108A2/xx not_active Application Discontinuation
- 2002-11-22 HK HK02108477.3A patent/HK1047226A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
AU5060499A (en) | 2001-03-05 |
HUP0202497A3 (en) | 2004-05-28 |
ZA200200926B (en) | 2002-11-27 |
SK1832002A3 (en) | 2002-08-06 |
OA12003A (en) | 2006-04-18 |
MXPA02001272A (es) | 2002-07-22 |
WO2001010405A1 (en) | 2001-02-15 |
TR200200467T2 (tr) | 2002-08-21 |
EP1206249A1 (en) | 2002-05-22 |
CA2378468A1 (en) | 2001-02-15 |
CN1376059A (zh) | 2002-10-23 |
AU774957B2 (en) | 2004-07-15 |
WO2001010419A1 (en) | 2001-02-15 |
AU6309900A (en) | 2001-03-05 |
CZ2002415A3 (cs) | 2002-08-14 |
HK1047226A1 (zh) | 2003-02-14 |
NZ516959A (en) | 2003-10-31 |
JP2003506400A (ja) | 2003-02-18 |
EA200200126A1 (ru) | 2002-10-31 |
AP2002002410A0 (en) | 2002-03-31 |
IL147966A0 (en) | 2002-09-12 |
EP1206249A4 (en) | 2004-12-22 |
PL353321A1 (en) | 2003-11-17 |
HUP0202497A2 (hu) | 2002-11-28 |
HRP20020108A2 (en) | 2003-12-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008. |