BR0012981A - Sistema para liberação oral de droga hidrodinamicamente balanceado - Google Patents

Sistema para liberação oral de droga hidrodinamicamente balanceado

Info

Publication number
BR0012981A
BR0012981A BR0012981-0A BR0012981A BR0012981A BR 0012981 A BR0012981 A BR 0012981A BR 0012981 A BR0012981 A BR 0012981A BR 0012981 A BR0012981 A BR 0012981A
Authority
BR
Brazil
Prior art keywords
drug
release system
drug release
oral drug
time
Prior art date
Application number
BR0012981-0A
Other languages
English (en)
Inventor
Naresh Talwar
John N Staniforth
Michael J Tobyn
Original Assignee
Ranbaxy Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd
Publication of BR0012981A publication Critical patent/BR0012981A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"SISTEMA PARA LIBERAçãO ORAL DE DROGA HIDRODINAMICAMENTE BALANCEADO". A presente invenção refere-se a um sistema gastro-retentor de liberação oral de droga compreendendo uma matriz de elevada porosidade e, pelo menos, uma droga, açúcar(es) , componentes geradores de gás e, opcionalmente, componentes auxiliares farmaceuticamente aceitáveis. A composição farmacêutica, seja sob a forma de pílulas (forma de dosagem multiparticulada ou unitária), glóbulos, grânulos ou cápsulas é retida no estómago, enquanto a droga é seletivamente liberada a nível gástrico e em partes superiores do intestino delgado por um longo período de tempo.
BR0012981-0A 1999-08-04 2000-08-01 Sistema para liberação oral de droga hidrodinamicamente balanceado BR0012981A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/IB1999/001386 WO2001010405A1 (en) 1999-08-04 1999-08-04 Hydrodynamically balanced oral drug delivery system
PCT/IB2000/001083 WO2001010419A1 (en) 1999-08-04 2000-08-01 Hydrodynamically balancing oral drug delivery system

Publications (1)

Publication Number Publication Date
BR0012981A true BR0012981A (pt) 2002-06-18

Family

ID=11004886

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0012981-0A BR0012981A (pt) 1999-08-04 2000-08-01 Sistema para liberação oral de droga hidrodinamicamente balanceado

Country Status (21)

Country Link
EP (1) EP1206249A4 (pt)
JP (1) JP2003506400A (pt)
CN (1) CN1376059A (pt)
AP (1) AP2002002410A0 (pt)
AU (2) AU5060499A (pt)
BR (1) BR0012981A (pt)
CA (1) CA2378468A1 (pt)
CZ (1) CZ2002415A3 (pt)
EA (1) EA200200126A1 (pt)
HK (1) HK1047226A1 (pt)
HR (1) HRP20020108A2 (pt)
HU (1) HUP0202497A3 (pt)
IL (1) IL147966A0 (pt)
MX (1) MXPA02001272A (pt)
NZ (1) NZ516959A (pt)
OA (1) OA12003A (pt)
PL (1) PL353321A1 (pt)
SK (1) SK1832002A3 (pt)
TR (1) TR200200467T2 (pt)
WO (2) WO2001010405A1 (pt)
ZA (1) ZA200200926B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100457458B1 (ko) * 2001-04-02 2004-11-17 삼아약품 주식회사 속용정 및 그의 제조방법
KR20040018394A (ko) 2001-07-04 2004-03-03 썬 파마슈티컬 인더스트리스 리미티드 위 정체 제어되는 약물 전달 계
WO2003037296A2 (en) * 2001-10-29 2003-05-08 Labopharm Inc. Methods and dosage forms for improving the bioavailability of therapeutic agents
US20050226926A1 (en) 2002-07-25 2005-10-13 Pfizer Inc Sustained-release tablet composition of pramipexole
WO2005020879A2 (en) * 2003-08-27 2005-03-10 Vecta Ltd. Compositions for treating pathologies that necessitate suppression of gastric acid secretion
TW200533391A (en) * 2004-03-25 2005-10-16 Sun Pharmaceutical Ind Ltd Gastric retention drug delivery system
CN101005830B (zh) 2004-08-13 2010-09-29 贝林格尔·英格海姆国际有限公司 包含普拉克索或其可药用盐的延长释放片剂、其制备方法及用途
DE102004042139B4 (de) * 2004-08-31 2009-06-10 Aristocon Verwaltungs- Gmbh Perorale Darreichungsformen zur Erzielung eines Retardierungseffektes nach der Arzneimitteleinnahme mit einer Mahlzeit
EP1690540A1 (en) * 2005-02-15 2006-08-16 Neuro3D Composition comprising ocaperidone
AU2006330526B2 (en) 2005-12-22 2012-09-27 Oakwood Laboratories, Llc Sublimable sustained release delivery system and method of making same
EP1886665A1 (en) * 2006-08-01 2008-02-13 Boehringer Ingelheim Pharma GmbH & Co. KG Gastro retentive delivery system
US10888521B2 (en) * 2007-03-02 2021-01-12 Farnam Companies, Inc. Sustained release compositions using wax-like materials
BRPI0917444A2 (pt) 2008-08-15 2015-12-01 Depomed Inc composições farmacêuticas de retenção gástrica para o tratamento e prevenção de doenas do snc
EP2329810A4 (en) 2008-08-18 2012-09-19 Team Academy Of Pharmaceutical Science DRUG DISPENSING SYSTEM WITH MAGNETIC RETENTION, MANUFACTURING PROCESS AND APPLICATION
JP2012505203A (ja) 2008-10-08 2012-03-01 バイオプラス ライフ サイエンスズ ピーヴイティ リミテッド 持続放出性薬剤送達システム
EP2283824B1 (en) 2009-07-30 2017-04-19 Special Products Line S.p.A. Compositions and formulations based on swellable matrices for sustained release of poorly soluble drugs such as clarithromycin
JP2013103879A (ja) * 2011-11-10 2013-05-30 Nakanihon Capsule Co Ltd ハードカプセル
KR102241487B1 (ko) 2013-02-20 2021-04-16 주식회사 종근당 제어방출 펠릿으로 된 약제학적 조성물
WO2014144661A1 (en) * 2013-03-15 2014-09-18 Aprecia Pharmaceuticals Compny Rapidly dispersible dosage form of topiramate
CN103462917A (zh) * 2013-09-12 2013-12-25 南京正宽医药科技有限公司 一种用于抗病毒的阿昔洛韦片剂及其制备方法
EP3468382A4 (en) * 2016-06-14 2020-01-22 Prevtec Microbia Inc FOOD GRANULES FOR ANIMALS COMPRISING A FOOD ADDITIVE, METHOD FOR MANUFACTURING AND USING THE SAME
US10987311B2 (en) 2017-06-16 2021-04-27 Kashiv Specialty Pharmaceuticals, Llc Extended release compositions comprising pyridostigmine
US10588863B2 (en) 2017-06-16 2020-03-17 Kashiv Biosciences, Llc Extended release compositions comprising pyridostigmine
WO2018232413A1 (en) 2017-06-16 2018-12-20 Kashiv Pharma Llc Gastroretentive dosage forms for sustained drug delivery
CN107375287B (zh) * 2017-08-22 2019-11-29 安徽省肿瘤医院 一种硫酸阿托品在制备治疗原发性肝癌药物中的用途
CN107441115A (zh) * 2017-08-22 2017-12-08 安徽省肿瘤医院 一种维拉帕米联合碳酸氢钠在制备原发性肝癌治疗药物中的用途
CN107349195A (zh) * 2017-08-22 2017-11-17 安徽省肿瘤医院 一种维拉帕米在制备治疗转移性肝癌药物中的用途
JP7048770B2 (ja) 2018-06-18 2022-04-05 アムニール コンプレックス プロダクツ リサーチ エルエルシー ピリドスチグミンを含む持続放出組成物
JP7034343B2 (ja) * 2018-06-27 2022-03-11 アムニール コンプレックス プロダクツ リサーチ エルエルシー 自己調節性の浸透性胃保持性薬物送達システム
WO2020230089A1 (en) 2019-05-14 2020-11-19 Clexio Biosciences Ltd. Treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease
WO2022195476A1 (en) 2021-03-15 2022-09-22 Clexio Biosciences Ltd. Gastroretentive devices for assessment of intragastric conditions

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH675537A5 (pt) * 1988-03-25 1990-10-15 Ciba Geigy Ag
US5096714A (en) * 1988-06-28 1992-03-17 Hauser-Kuhrts, Inc. Prolonged release drug tablet formulations
WO1991006281A1 (en) * 1989-10-26 1991-05-16 Nippon Shinyaku Co., Ltd. Gastric preparation
MX9300110A (es) * 1992-01-13 1994-07-29 Gerhard Gergely Preparacion farmaceutica en la forma de una tableta de efervescencia o de desintegracion o de un granulado de tipo instanteneo y procedimiento para su preparacion.
GB9322314D0 (en) * 1993-10-29 1993-12-15 Scherer Ltd R P Foam generating capsules
DE4403943A1 (de) * 1994-02-08 1995-08-10 Hexal Pharma Gmbh Orale Azrneimittelzubereitung mit Diclofenac-Natrium
GB9418530D0 (en) * 1994-09-14 1994-11-02 Glaxo Group Ltd Medicaments
US5788987A (en) * 1997-01-29 1998-08-04 Poli Industria Chimica Spa Methods for treating early morning pathologies
IT1293764B1 (it) * 1997-07-23 1999-03-10 Chiesi Farma Spa Composizioni farmaceutiche sotto forma di compresse effervescenti contenenti un principio attivo instabile in presenza di acqua

Also Published As

Publication number Publication date
AP2002002410A0 (en) 2002-03-31
OA12003A (en) 2006-04-18
WO2001010405A1 (en) 2001-02-15
CA2378468A1 (en) 2001-02-15
AU774957B2 (en) 2004-07-15
SK1832002A3 (en) 2002-08-06
AU5060499A (en) 2001-03-05
WO2001010419A1 (en) 2001-02-15
EP1206249A4 (en) 2004-12-22
EA200200126A1 (ru) 2002-10-31
JP2003506400A (ja) 2003-02-18
NZ516959A (en) 2003-10-31
TR200200467T2 (tr) 2002-08-21
EP1206249A1 (en) 2002-05-22
CZ2002415A3 (cs) 2002-08-14
HUP0202497A3 (en) 2004-05-28
CN1376059A (zh) 2002-10-23
HK1047226A1 (zh) 2003-02-14
AU6309900A (en) 2001-03-05
IL147966A0 (en) 2002-09-12
MXPA02001272A (es) 2002-07-22
PL353321A1 (en) 2003-11-17
HUP0202497A2 (hu) 2002-11-28
ZA200200926B (en) 2002-11-27
HRP20020108A2 (en) 2003-12-31

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008.