BRPI0917444A2 - composições farmacêuticas de retenção gástrica para o tratamento e prevenção de doenas do snc - Google Patents
composições farmacêuticas de retenção gástrica para o tratamento e prevenção de doenas do sncInfo
- Publication number
- BRPI0917444A2 BRPI0917444A2 BRPI0917444A BRPI0917444A BRPI0917444A2 BR PI0917444 A2 BRPI0917444 A2 BR PI0917444A2 BR PI0917444 A BRPI0917444 A BR PI0917444A BR PI0917444 A BRPI0917444 A BR PI0917444A BR PI0917444 A2 BRPI0917444 A2 BR PI0917444A2
- Authority
- BR
- Brazil
- Prior art keywords
- snc
- diseases
- prevention
- treatment
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
- A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8933908P | 2008-08-15 | 2008-08-15 | |
US12227608P | 2008-12-12 | 2008-12-12 | |
PCT/US2009/053937 WO2010019915A1 (en) | 2008-08-15 | 2009-08-14 | Gastric retentive pharmaceutical compositions for treatment and prevention of cns disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0917444A2 true BRPI0917444A2 (pt) | 2015-12-01 |
Family
ID=41200355
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0917444A BRPI0917444A2 (pt) | 2008-08-15 | 2009-08-14 | composições farmacêuticas de retenção gástrica para o tratamento e prevenção de doenas do snc |
Country Status (11)
Country | Link |
---|---|
US (3) | US9161911B2 (pt) |
EP (1) | EP2326310B1 (pt) |
JP (1) | JP2012500221A (pt) |
KR (1) | KR101687781B1 (pt) |
CN (1) | CN102202656A (pt) |
AU (1) | AU2009281752B2 (pt) |
BR (1) | BRPI0917444A2 (pt) |
CA (1) | CA2733787C (pt) |
ES (1) | ES2740360T3 (pt) |
MX (1) | MX340249B (pt) |
WO (1) | WO2010019915A1 (pt) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
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US10179130B2 (en) | 1999-10-29 | 2019-01-15 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
KR101216270B1 (ko) | 1999-10-29 | 2012-12-31 | 유로-셀티크 소시에떼 아노뉨 | 서방성 하이드로코돈 제형 |
AU2002227383B2 (en) | 2000-10-30 | 2004-07-08 | Euro-Celtique S.A. | Controlled release hydrocodone formulations |
PL2276473T3 (pl) | 2008-04-18 | 2017-03-31 | Intec Pharma Ltd. | Podawanie leku karbidopa/lewodopa o przedłużonej retencji w żołądku |
WO2010019915A1 (en) | 2008-08-15 | 2010-02-18 | Depomed Inc. | Gastric retentive pharmaceutical compositions for treatment and prevention of cns disorders |
US20140017303A1 (en) | 2010-11-01 | 2014-01-16 | Intec Pharma Ltd. | Accordion pill comprising levodopa for an improved treatment of parkinson's disease symptoms |
US10322120B2 (en) | 2012-07-31 | 2019-06-18 | Persion Pharmaceuticals Llc | Treating pain in patients with hepatic impairment |
US20140161879A1 (en) * | 2012-07-31 | 2014-06-12 | Zogenix, Inc. | Treating pain in patients with hepatic impairment |
WO2014100077A1 (en) * | 2012-12-21 | 2014-06-26 | Merck Sharp & Dohme Corp. | Gastro-retentive formulations |
US20180161279A1 (en) * | 2016-12-14 | 2018-06-14 | Amgen Inc. | Gastro-retentive modified release dosage forms for oprozomib and process to make thereof |
US10987311B2 (en) | 2017-06-16 | 2021-04-27 | Kashiv Specialty Pharmaceuticals, Llc | Extended release compositions comprising pyridostigmine |
US10588863B2 (en) | 2017-06-16 | 2020-03-17 | Kashiv Biosciences, Llc | Extended release compositions comprising pyridostigmine |
CA3031412C (en) | 2017-06-16 | 2020-08-11 | Kashiv Pharma Llc | Gastroretentive dosage forms for sustained drug delivery |
US11337920B2 (en) | 2017-12-18 | 2022-05-24 | Tris Pharma, Inc. | Pharmaceutical composition comprising GHB gastro-retentive raft forming systems having trigger pulse drug release |
EP3737353A1 (en) | 2017-12-18 | 2020-11-18 | Tris Pharma, Inc. | Ghb pharmaceutical compositions comprising a floating interpenetrating polymer network forming system |
US11337919B2 (en) | 2017-12-18 | 2022-05-24 | Tris Pharma, Inc. | Modified release drug powder composition comprising gastro-retentive RAFT forming systems having trigger pulse drug release |
WO2019148087A1 (en) | 2018-01-29 | 2019-08-01 | Duke University | Compositions and methods of enhancing 5-hydroxytryptophan bioavailability |
US11547689B2 (en) * | 2018-03-23 | 2023-01-10 | Intrance International Ab | Continuous administration of pharmaceutical composition for treatment of neurodegenerative disorders |
CA3061382C (en) | 2018-06-18 | 2020-12-15 | Kashiv Biosciences, Llc | Extended release compositions comprising pyridostigmine |
KR20210031910A (ko) | 2018-06-19 | 2021-03-23 | 싱가포르국립대학교 | 다양한 적응증에 대한 향상된 생체 이용률을 위한 5-하이드록시트립토판의 제형 |
US11389398B2 (en) | 2019-05-14 | 2022-07-19 | Clexio Biosciences Ltd. | Gastroretentive treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease |
EP3986382A1 (en) * | 2019-06-21 | 2022-04-27 | Kashiv Biosciences, LLC | Gastroretentive dosage forms of levodopa and carbidopa |
US11730708B2 (en) * | 2019-12-11 | 2023-08-22 | Evonik Operations Gmbh | Dosage form for use in treating or preventing of a disease |
WO2022044045A1 (en) * | 2020-08-26 | 2022-03-03 | Rubicon Research Private Limited | Modified release formulations of levodopa |
WO2022195476A1 (en) | 2021-03-15 | 2022-09-22 | Clexio Biosciences Ltd. | Gastroretentive devices for assessment of intragastric conditions |
CN116801868A (zh) | 2021-07-30 | 2023-09-22 | 埃维西亚治疗公司 | 5-羟色氨酸胃滞留剂型 |
US11779567B2 (en) | 2021-10-14 | 2023-10-10 | Evecxia Therapeutics, Inc. | Method for optimizing 5-hydroxytryptamine function in the brain for therapeutic purposes |
WO2024024865A1 (ja) * | 2022-07-28 | 2024-02-01 | 大原薬品工業株式会社 | レボドパ持続性製剤 |
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CA2673485A1 (en) | 2007-01-15 | 2008-07-24 | Kissei Pharmaceutical Co., Ltd. | Gastric retention-type sustained-release levodopa preparation |
US20090028941A1 (en) * | 2007-07-27 | 2009-01-29 | Depomed, Inc. | Pulsatile gastric retentive dosage forms |
PL2276473T3 (pl) | 2008-04-18 | 2017-03-31 | Intec Pharma Ltd. | Podawanie leku karbidopa/lewodopa o przedłużonej retencji w żołądku |
WO2010019915A1 (en) | 2008-08-15 | 2010-02-18 | Depomed Inc. | Gastric retentive pharmaceutical compositions for treatment and prevention of cns disorders |
-
2009
- 2009-08-14 WO PCT/US2009/053937 patent/WO2010019915A1/en active Application Filing
- 2009-08-14 CN CN2009801413422A patent/CN102202656A/zh active Pending
- 2009-08-14 AU AU2009281752A patent/AU2009281752B2/en not_active Ceased
- 2009-08-14 KR KR1020117005446A patent/KR101687781B1/ko active IP Right Grant
- 2009-08-14 CA CA2733787A patent/CA2733787C/en not_active Expired - Fee Related
- 2009-08-14 JP JP2011523207A patent/JP2012500221A/ja active Pending
- 2009-08-14 MX MX2011001639A patent/MX340249B/es active IP Right Grant
- 2009-08-14 US US12/541,836 patent/US9161911B2/en not_active Expired - Fee Related
- 2009-08-14 BR BRPI0917444A patent/BRPI0917444A2/pt not_active IP Right Cessation
- 2009-08-14 ES ES09791546T patent/ES2740360T3/es active Active
- 2009-08-14 EP EP09791546.6A patent/EP2326310B1/en not_active Not-in-force
-
2015
- 2015-09-08 US US14/847,968 patent/US9566258B2/en not_active Expired - Fee Related
-
2017
- 2017-02-01 US US15/421,802 patent/US9937142B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES2740360T3 (es) | 2020-02-05 |
KR101687781B1 (ko) | 2016-12-20 |
JP2012500221A (ja) | 2012-01-05 |
MX340249B (es) | 2016-07-01 |
EP2326310A1 (en) | 2011-06-01 |
US20150374653A1 (en) | 2015-12-31 |
AU2009281752A1 (en) | 2010-02-18 |
CA2733787C (en) | 2016-09-06 |
CN102202656A (zh) | 2011-09-28 |
EP2326310B1 (en) | 2019-05-15 |
US9566258B2 (en) | 2017-02-14 |
US20170143654A1 (en) | 2017-05-25 |
AU2009281752B2 (en) | 2016-11-17 |
MX2011001639A (es) | 2011-06-30 |
US9161911B2 (en) | 2015-10-20 |
KR20110055604A (ko) | 2011-05-25 |
US20100040689A1 (en) | 2010-02-18 |
CA2733787A1 (en) | 2010-02-18 |
WO2010019915A1 (en) | 2010-02-18 |
US9937142B2 (en) | 2018-04-10 |
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