WO2006040779A3 - Controlled release gastric floating matrix formulation containing imatinib - Google Patents

Controlled release gastric floating matrix formulation containing imatinib Download PDF

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Publication number
WO2006040779A3
WO2006040779A3 PCT/IN2005/000333 IN2005000333W WO2006040779A3 WO 2006040779 A3 WO2006040779 A3 WO 2006040779A3 IN 2005000333 W IN2005000333 W IN 2005000333W WO 2006040779 A3 WO2006040779 A3 WO 2006040779A3
Authority
WO
WIPO (PCT)
Prior art keywords
controlled release
formulation containing
gastric floating
matrix formulation
floating matrix
Prior art date
Application number
PCT/IN2005/000333
Other languages
French (fr)
Other versions
WO2006040779A2 (en
Inventor
Durga Maheswari Parvataneni
Appala Swamy Naidu Rongala
Khadgapathi Podile
Chowdary Nannapaneni Venkaiah
Original Assignee
Natco Pharma Ltd
Durga Maheswari Parvataneni
Appala Swamy Naidu Rongala
Khadgapathi Podile
Chowdary Nannapaneni Venkaiah
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Natco Pharma Ltd, Durga Maheswari Parvataneni, Appala Swamy Naidu Rongala, Khadgapathi Podile, Chowdary Nannapaneni Venkaiah filed Critical Natco Pharma Ltd
Publication of WO2006040779A2 publication Critical patent/WO2006040779A2/en
Publication of WO2006040779A3 publication Critical patent/WO2006040779A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A pharmaceutical formulation and its process for the preparation of controlled release gastric floating matrix solid oral dosage form of Imatinib or its pharmaceutically acceptable salts and its polymorphs such as β, α2, Form I and Form 2 thereof for once daily administration in the form of coated tablet or minitablets and / or pellets filled in hard gelatin capsules.
PCT/IN2005/000333 2004-10-11 2005-10-06 Controlled release gastric floating matrix formulation containing imatinib WO2006040779A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1049CH2004 2004-10-11
IN1049/CHE/2004 2004-10-11

Publications (2)

Publication Number Publication Date
WO2006040779A2 WO2006040779A2 (en) 2006-04-20
WO2006040779A3 true WO2006040779A3 (en) 2006-08-17

Family

ID=36148723

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2005/000333 WO2006040779A2 (en) 2004-10-11 2005-10-06 Controlled release gastric floating matrix formulation containing imatinib

Country Status (1)

Country Link
WO (1) WO2006040779A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY148074A (en) * 2005-05-10 2013-02-28 Novartis Ag Pharmaceutical compositions comprising imatinib and a release retardant
WO2007106957A1 (en) * 2006-03-21 2007-09-27 Laboratoires Smb S.A. Multiple units controlled-release floating dosage forms
EP1920767A1 (en) * 2006-11-09 2008-05-14 Abbott GmbH & Co. KG Melt-processed imatinib dosage form
CA2680249A1 (en) * 2007-03-12 2008-09-18 Dr. Reddy's Laboratories, Inc. Imatinib mesylate
FR2918566B1 (en) 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa STABLE PHARMACEUTICAL COMPOSITION OF A WATER SOLUBLE SALT OF VINFLUNINE.
US20090087489A1 (en) 2007-09-25 2009-04-02 Bella Gerber Imatinib compositions
EP2255792A1 (en) * 2009-05-20 2010-12-01 Ratiopharm GmbH Pharmaceutical compositions for N-[2-(Diethylamino)ethyl]5-[(fluoro-1,2-dihydro-2-oxo-3H-indole-3-ylidene) methyl]-2,4-dimenthyl-1H-pyrrole-3-carboxamide
CZ2009570A3 (en) 2009-08-26 2011-03-09 Zentiva, K. S. Preparation, stabilization and use of imatinib mesylate polymorphs for development of medicinal forms
MX2013001653A (en) 2010-08-11 2013-05-22 Synthon Bv Pharmaceutical granulate comprising imatinib mesylate
WO2012080703A1 (en) * 2010-12-15 2012-06-21 Cipla Limited Pharmaceutical composition comprising imatinib
US9750700B2 (en) * 2011-06-22 2017-09-05 Natco Pharma Limited Imatinib mesylate oral pharmaceutical composition and process for preparation thereof
WO2014041551A1 (en) 2012-09-14 2014-03-20 Natco Pharma Limited Formulation comprising imatinib as oral solution
US20150110871A1 (en) * 2014-06-02 2015-04-23 David Wong Gastric retentive tablet compositions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003090720A1 (en) * 2002-04-23 2003-11-06 Novartis Ag High drug load tablet
WO2003090750A1 (en) * 2002-04-24 2003-11-06 Board Of Regents, The University Of Texas System Pdgf receptor tyrosine kinase inhibitors for the treatment of polycythemia vera

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003090720A1 (en) * 2002-04-23 2003-11-06 Novartis Ag High drug load tablet
WO2003090750A1 (en) * 2002-04-24 2003-11-06 Board Of Regents, The University Of Texas System Pdgf receptor tyrosine kinase inhibitors for the treatment of polycythemia vera

Also Published As

Publication number Publication date
WO2006040779A2 (en) 2006-04-20

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