BR0008258A - Processo de moldagem por injeção paracopolìmeros de (met) acrilato contendo gruposneutros e ácidos - Google Patents

Processo de moldagem por injeção paracopolìmeros de (met) acrilato contendo gruposneutros e ácidos

Info

Publication number
BR0008258A
BR0008258A BR0008258-9A BR0008258A BR0008258A BR 0008258 A BR0008258 A BR 0008258A BR 0008258 A BR0008258 A BR 0008258A BR 0008258 A BR0008258 A BR 0008258A
Authority
BR
Brazil
Prior art keywords
meth
acids
injection molding
molding process
polymers containing
Prior art date
Application number
BR0008258-9A
Other languages
English (en)
Inventor
Hans-Ulrich Petereit
Thomas Beckert
Manfred Assmus
Hoess Werner
Wolfgang Fuchs
Hartmut Schikowsky
Original Assignee
Roehm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roehm Gmbh filed Critical Roehm Gmbh
Publication of BR0008258A publication Critical patent/BR0008258A/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/077—Manufacturing capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
    • B29C45/0001—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor characterised by the choice of material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Manufacturing & Machinery (AREA)
  • Epidemiology (AREA)
  • Mechanical Engineering (AREA)
  • Injection Moulding Of Plastics Or The Like (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Moulds For Moulding Plastics Or The Like (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Containers Having Bodies Formed In One Piece (AREA)

Abstract

Patente de Invenção: "PROCESSO DE MOLDAGEM PORINJEçãO PARA COPOLìMEROS DE (MET)ACRILATOCONTENDO GRUPOS NEUTROS E áCIDOS". A invençãorefere-se a um processo para preparação de corpos moldados pormeio de moldagem por injeção com as etapas de processo: A)fusão de uma mistura de: a) um copolímero de (met)acrilato, que secompõe de 40 até 100% em peso de C~ 1~-C~ 4~ -alquilésteresradicalmente polimerizáveis do ácido acrílico ou do ácidometacrílico e 0 até 60% em peso de monómeros de (met)acrilatocom um grupo aniónico no radical alquila, que b) contém 0,1 até3% em peso de um agente de separação e opcionalmente c) 0 até50% em peso de um agente de fixação seco, d) 0 até 30% em pesode um amaciante, e) 0 até 100% em peso de aditivo oucoadjuvantes, f) 0 até 100% em peso de uma substânciafarmaceuticamente ativa, g) podem estar contidos de 0 até 20% empeso de um outro polímero ou copolímero na mistura, sendo queos dados em quantidade dos componentes b) até g) referem-se aocopolímero de (met)acrilato e a mistura antes da fusão apresentaum teor de constituintes de baixo ponto de fusão com uma pressãode vapor de pelo menos 1,9 bar a 120<198>C acima de 0,5% empeso, B) desgaseificação da mistura no estado termoplástico atemperaturas de pelo menos 120<198>C, com o que o teor dosconstituintes de baixo ponto de ebulição com uma pressao devapor de pelo menos 1,9 bar a 120<198>C é reduzida a no máximo0,5% em peso, C) injeção da mistura derretida e desgaseificada noespaço vazio de um dispositivo de moldagem por injeção, sendoque o espaço vazio apresenta uma temperatura que situa-se pelomenos 10<198>C abaixo da temperatura de vidro do copolímerode (met)acrilato, resfriamento da mistura de fundido e desenformedo corpo moldado obtido da forma.
BR0008258-9A 1999-12-17 2000-12-09 Processo de moldagem por injeção paracopolìmeros de (met) acrilato contendo gruposneutros e ácidos BR0008258A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19961334A DE19961334A1 (de) 1999-12-17 1999-12-17 Spritzgußverfahren für neutrale und säuregruppenhaltige (Meth)acrylat-Copolymere
PCT/EP2000/012467 WO2001043935A2 (de) 1999-12-17 2000-12-09 Spritzgussverfahren für neutrale und säuregruppenhaltige (meth)acrylat-copolymere

Publications (1)

Publication Number Publication Date
BR0008258A true BR0008258A (pt) 2001-12-11

Family

ID=7933336

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0008258-9A BR0008258A (pt) 1999-12-17 2000-12-09 Processo de moldagem por injeção paracopolìmeros de (met) acrilato contendo gruposneutros e ácidos

Country Status (18)

Country Link
US (2) US20020160042A1 (pt)
EP (1) EP1150820B1 (pt)
JP (1) JP2003516881A (pt)
KR (1) KR100810919B1 (pt)
CN (1) CN1378499A (pt)
AT (1) ATE262401T1 (pt)
AU (1) AU2364001A (pt)
BG (1) BG64935B1 (pt)
BR (1) BR0008258A (pt)
CA (1) CA2363071C (pt)
DE (2) DE19961334A1 (pt)
ES (1) ES2214341T3 (pt)
IL (1) IL144833A (pt)
MX (1) MXPA01008224A (pt)
PL (1) PL196144B1 (pt)
SK (1) SK11752001A3 (pt)
TR (2) TR200102392T1 (pt)
WO (1) WO2001043935A2 (pt)

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PE20060003A1 (es) * 2004-03-12 2006-03-01 Smithkline Beecham Plc Formulacion farmaceutica polimerica para moldear por inyeccion
DE102004022540A1 (de) 2004-05-05 2005-12-08 Röhm GmbH & Co. KG Formmasse für Formkörper mit hoher Witterungsbeständigkeit
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DE102004058083A1 (de) 2004-12-01 2006-06-08 Röhm GmbH & Co. KG Gedeckt eingefärbte, infrarotreflektierende Kunststoffformmasse
CN101137701B (zh) * 2005-04-18 2011-02-09 赢创罗姆有限公司 由含纳米级无机粒子的热塑性塑料构成的模塑材料和模制品、所述模塑材料和模制品的制备方法及其用途
DE102005021335A1 (de) * 2005-05-04 2006-11-09 Röhm Gmbh Verfahren zur Herstellung von Perlpolymerisaten mit einer mittleren Teilchengröße im Bereich von 1 µm bis 40 µm sowie Perlpolymerisat aufweisende Formmassen und Formkörper
JP2009503020A (ja) 2005-08-03 2009-01-29 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 肥満症の治療におけるフリバンセリンの使用
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Also Published As

Publication number Publication date
MXPA01008224A (es) 2002-04-24
TR200400862T4 (tr) 2004-06-21
ES2214341T3 (es) 2004-09-16
EP1150820A1 (de) 2001-11-07
BG105799A (en) 2002-04-30
DE19961334A1 (de) 2001-06-21
ATE262401T1 (de) 2004-04-15
TR200102392T1 (tr) 2002-11-21
AU2364001A (en) 2001-06-25
BG64935B1 (bg) 2006-10-31
DE50005789D1 (de) 2004-04-29
JP2003516881A (ja) 2003-05-20
SK11752001A3 (sk) 2002-08-06
US20080260814A1 (en) 2008-10-23
WO2001043935A2 (de) 2001-06-21
KR100810919B1 (ko) 2008-03-10
PL349961A1 (en) 2002-10-21
PL196144B1 (pl) 2007-12-31
IL144833A (en) 2005-08-31
CA2363071C (en) 2009-03-10
CA2363071A1 (en) 2001-06-21
KR20010102218A (ko) 2001-11-15
WO2001043935A3 (de) 2002-04-18
US20020160042A1 (en) 2002-10-31
EP1150820B1 (de) 2004-03-24
CN1378499A (zh) 2002-11-06
IL144833A0 (en) 2002-06-30

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B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]