BR0004534A - Composto, composição farmacêutica, agente contendo um composto, e uso de um composto. - Google Patents
Composto, composição farmacêutica, agente contendo um composto, e uso de um composto.Info
- Publication number
- BR0004534A BR0004534A BR0004534-9A BR0004534A BR0004534A BR 0004534 A BR0004534 A BR 0004534A BR 0004534 A BR0004534 A BR 0004534A BR 0004534 A BR0004534 A BR 0004534A
- Authority
- BR
- Brazil
- Prior art keywords
- group
- compound
- optionally substituted
- pyrrole ring
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Virology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"COMPOSTO, COMPOSIçãO FARMACêUTICA, AGENTE CONTENDO UM COMPOSTO, E, USO DE UM COMPOSTO" Compostos de fórmula (I): [em que: A é um anel pirrol; R^ 1^ é um grupo arila ou heteroarila opcionalmente substituído; R^ 2^ representa um grupo heteroarila contendo nitrogênio opcionalmente substituído; R^ 3^ representa um grupo da fórmula -X-R^ 4^, em que X é uma ligação simples ou um grupo alquileno, alquenileno ou alquinileno opcionalmente substituído, e R^ 4^ é um grupo cicloalquila substituído, um grupo arila substituído, um grupo heterociclila substituído, um grupo heterociclila contendo nitrogênio opcionalmente substituído, um grupo heterarila substituído, um grupo heterarila contendo nitrogênio opcionalmente substituído, ou -NR^ a^R^ b^, em que cada um de R^ a^ e R^ b^ é um átomo de hidrogênio ou um grupo alquila, alquenila, alquinila, aralquila ou alquilsulfonila; DESDE QUE os referidos substituintes R^ 1^ e R^ 3^ sejam ligados aos dois átomos do referido anel pirrol que são adjacentes ao átomo do anel pirrol ao qual o referido substituinte R^ 2^ está ligado] apresentam excelente atividade inibidora contra a produção de citosinas inflamatórias.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP20549199 | 1999-07-21 | ||
JP36967899 | 1999-12-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0004534A true BR0004534A (pt) | 2001-02-28 |
Family
ID=26515088
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0004534-9A BR0004534A (pt) | 1999-07-21 | 2000-07-21 | Composto, composição farmacêutica, agente contendo um composto, e uso de um composto. |
Country Status (22)
Country | Link |
---|---|
EP (2) | EP1243589A1 (pt) |
KR (2) | KR100776958B1 (pt) |
CN (1) | CN1294129C (pt) |
AR (1) | AR024904A1 (pt) |
AT (1) | ATE264319T1 (pt) |
AU (1) | AU773453B2 (pt) |
BR (1) | BR0004534A (pt) |
CA (1) | CA2314373A1 (pt) |
DE (1) | DE60009804T2 (pt) |
DK (1) | DK1070711T3 (pt) |
ES (1) | ES2216826T3 (pt) |
HK (2) | HK1047587A1 (pt) |
HU (1) | HUP0002846A2 (pt) |
ID (1) | ID26611A (pt) |
IL (1) | IL137365A0 (pt) |
MX (1) | MXPA00007199A (pt) |
NO (1) | NO20003734L (pt) |
NZ (1) | NZ505924A (pt) |
PL (1) | PL341620A1 (pt) |
PT (1) | PT1070711E (pt) |
TR (1) | TR200002120A2 (pt) |
TW (1) | TWI259834B (pt) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPQ105499A0 (en) | 1999-06-18 | 1999-07-08 | Biota Scientific Management Pty Ltd | Antiviral agents |
US7122666B2 (en) | 1999-07-21 | 2006-10-17 | Sankyo Company, Limited | Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses |
EP1352906A4 (en) * | 2001-01-18 | 2004-06-16 | Sankyo Co | COMPOSITIONS FOR PREVENTION OR TREATMENT OF LIVER DISEASES |
WO2002057255A1 (fr) * | 2001-01-22 | 2002-07-25 | Sankyo Company, Limited | Derives du pyrrole substitues en 4 ou 5 |
ATE377598T1 (de) * | 2001-01-22 | 2007-11-15 | Sankyo Co | Durch bicyclische aminogruppen substituierte verbindungen |
EG23054A (en) * | 2001-01-22 | 2004-02-29 | Sankyo Co | Pyrrole derivatives their preparation and their therapeutic uses |
US7199124B2 (en) | 2001-02-02 | 2007-04-03 | Takeda Pharmaceutical Company Limited | JNK inhibitor |
WO2002080974A1 (fr) * | 2001-04-04 | 2002-10-17 | Sankyo Company, Limited | Utilisation medicale d'inhibiteur de production de cytokine |
WO2002094267A1 (fr) * | 2001-05-24 | 2002-11-28 | Sankyo Company, Limited | Preparation pharmaceutique pour prevenir ou traiter l'arthrite |
WO2003015781A1 (fr) * | 2001-08-15 | 2003-02-27 | Sankyo Company, Limited | Nouvelles compositions pharmaceutiques antidiabetiques |
EP1541571A4 (en) * | 2002-07-19 | 2008-12-03 | Sankyo Co | BICYCLIC, UNSATURATED TERTIARY AMINE COMPOUND |
US8809372B2 (en) | 2011-09-30 | 2014-08-19 | Asana Biosciences, Llc | Pyridine derivatives |
CA2850551A1 (en) * | 2011-09-30 | 2013-04-04 | Endo Pharmaceuticals Inc. | Pyridine derivatives |
US9630976B2 (en) | 2012-07-03 | 2017-04-25 | Ono Pharmaceutical Co., Ltd. | Compound having agonistic activity on somatostatin receptor, and use thereof for medical purposes |
WO2020113094A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5593992A (en) * | 1993-07-16 | 1997-01-14 | Smithkline Beecham Corporation | Compounds |
US5792778A (en) * | 1995-08-10 | 1998-08-11 | Merck & Co., Inc. | 2-substituted aryl pyrroles, compositions containing such compounds and methods of use |
JP3294616B2 (ja) * | 1995-08-10 | 2002-06-24 | メルク エンド カンパニー インコーポレーテッド | 2−置換アリールピロール、このような化合物を含む組成物及び使用方法 |
-
2000
- 2000-07-18 IL IL13736500A patent/IL137365A0/xx unknown
- 2000-07-20 DE DE60009804T patent/DE60009804T2/de not_active Expired - Fee Related
- 2000-07-20 EP EP02011912A patent/EP1243589A1/en not_active Withdrawn
- 2000-07-20 EP EP00306196A patent/EP1070711B1/en not_active Expired - Lifetime
- 2000-07-20 PT PT00306196T patent/PT1070711E/pt unknown
- 2000-07-20 TW TW089114563A patent/TWI259834B/zh not_active IP Right Cessation
- 2000-07-20 DK DK00306196T patent/DK1070711T3/da active
- 2000-07-20 AT AT00306196T patent/ATE264319T1/de not_active IP Right Cessation
- 2000-07-20 ES ES00306196T patent/ES2216826T3/es not_active Expired - Lifetime
- 2000-07-20 NO NO20003734A patent/NO20003734L/no not_active Application Discontinuation
- 2000-07-20 CA CA002314373A patent/CA2314373A1/en not_active Abandoned
- 2000-07-21 CN CNB001313037A patent/CN1294129C/zh not_active Expired - Fee Related
- 2000-07-21 AU AU48755/00A patent/AU773453B2/en not_active Ceased
- 2000-07-21 AR ARP000103779A patent/AR024904A1/es unknown
- 2000-07-21 ID IDP20000612A patent/ID26611A/id unknown
- 2000-07-21 NZ NZ505924A patent/NZ505924A/en unknown
- 2000-07-21 TR TR2000/02120A patent/TR200002120A2/xx unknown
- 2000-07-21 MX MXPA00007199A patent/MXPA00007199A/es unknown
- 2000-07-21 BR BR0004534-9A patent/BR0004534A/pt not_active Application Discontinuation
- 2000-07-21 KR KR1020000042064A patent/KR100776958B1/ko not_active IP Right Cessation
- 2000-07-21 HU HU0002846A patent/HUP0002846A2/hu unknown
- 2000-07-21 PL PL00341620A patent/PL341620A1/xx unknown
-
2001
- 2001-06-19 HK HK02108839.6A patent/HK1047587A1/zh unknown
- 2001-06-19 HK HK01104212A patent/HK1033671A1/xx not_active IP Right Cessation
-
2007
- 2007-01-22 KR KR1020070006711A patent/KR20070026708A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
MXPA00007199A (es) | 2003-03-12 |
PT1070711E (pt) | 2004-06-30 |
AU773453B2 (en) | 2004-05-27 |
AU4875500A (en) | 2001-02-01 |
NO20003734L (no) | 2001-01-22 |
KR20070026708A (ko) | 2007-03-08 |
ID26611A (id) | 2001-01-25 |
CN1294129C (zh) | 2007-01-10 |
HUP0002846A2 (hu) | 2002-07-29 |
HK1047587A1 (zh) | 2003-02-28 |
ATE264319T1 (de) | 2004-04-15 |
HK1033671A1 (en) | 2001-09-14 |
CN1295069A (zh) | 2001-05-16 |
KR100776958B1 (ko) | 2007-11-27 |
ES2216826T3 (es) | 2004-11-01 |
CA2314373A1 (en) | 2001-01-21 |
TR200002120A3 (tr) | 2001-06-21 |
KR20010049843A (ko) | 2001-06-15 |
TR200002120A2 (tr) | 2001-06-21 |
AR024904A1 (es) | 2002-10-30 |
IL137365A0 (en) | 2001-07-24 |
EP1070711A2 (en) | 2001-01-24 |
DE60009804D1 (de) | 2004-05-19 |
EP1070711B1 (en) | 2004-04-14 |
NO20003734D0 (no) | 2000-07-20 |
EP1070711A3 (en) | 2001-01-31 |
EP1243589A1 (en) | 2002-09-25 |
HU0002846D0 (en) | 2000-09-28 |
DK1070711T3 (da) | 2004-05-10 |
TWI259834B (en) | 2006-08-11 |
PL341620A1 (en) | 2001-01-29 |
NZ505924A (en) | 2001-11-30 |
DE60009804T2 (de) | 2005-01-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0004534A (pt) | Composto, composição farmacêutica, agente contendo um composto, e uso de um composto. | |
BR9908764A (pt) | Composto e seus sais farmaceuticamente aceitáveis ou ésteres hidrolisáveis in vivo, uso destes, processo para prepará-los, e, composição farmacêutica | |
TR199901578T2 (xx) | Klaritromisin form 0 kristali | |
BR0111754A (pt) | Uso de um composto, método para inibir aurora 2 quinase em um animal de sangue quente, composto, e, composição farmacêutica | |
NO995846D0 (no) | Oksazolidinon-antibakterielle midler med en tiokarbonylfunksjonalitet | |
PT1200412E (pt) | Agentes anti-proliferativos de imidazole | |
BR0014136A (pt) | Composto, uso do mesmo, métodos para a preparação de um composto, e para inibir aurora 2 quinase em um animal de sangue quente, e, composição farmacêutica | |
BR0207809A (pt) | Compostos heteroarila contendo nitrogênio possuindo atividade inibidora contra integrase de hiv | |
CA2011346A1 (en) | 2-(1-piperazinyl)-4-phenylcycloalkanopyridine derivatives, processes for the production thereof, and pharmaceutical composition containing the same | |
BR0014133A (pt) | Uso de um composto, composto, métodos de preparação de um composto, e para inibir aurora 2 quinase em um animal de sangue quente, e, composição farmacêutica | |
ATE297203T1 (de) | Antithrombotische mitteln | |
HUP0004333A2 (hu) | Új triazolo [4,5-d] pirimidin-származékok, eljárás előállításukra és ezeket tartalmazó gyógyszerkészítmények | |
ATE306261T1 (de) | Antithrombosemittel | |
BR0010520A (pt) | Novos compostos farmaceuticamente ativos | |
ATE177420T1 (de) | Cyclobutan-derivate als inhibitoren der squalen- synthetase und der protein-farnesyltransferase | |
TR200101961T2 (tr) | 1,2-halkalı kinolin türevleri | |
BR0208338A (pt) | Derivados de piridina | |
BR9706792A (pt) | Derivado de tiazol | |
BR0012610A (pt) | Novo derivado de difenilpiperidina | |
BR0112521A (pt) | Indolquinazolinonas | |
BR0309748A (pt) | Derivados de n-acil piperidina e composição compreendendo os mesmos | |
BR9712221A (pt) | Uso de pelo menos um 1,3-bis(n-lactamil) propano, composto, e, composições farmacêutica e cosmética. | |
BR0208566A (pt) | Derivados de beta-carbolina | |
HUP9800817A2 (hu) | Halogén-alk(en)oxi-szubsztituenseket tartalmazó szulfonil-amino-karbonil-triazolinon-származékok, intermedierjeik, előállításuk és alkalmazásuk, hatóanyagként ezeket a vegyületeket tartalmazó herbicid vagy fungicid készítmények | |
KR960017649A (ko) | 아미노사이클로펜탄 유도체 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 11, 13, 24 E 25 DA LPI |
|
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |