HK1047587A1 - 雜芳替代的洛衍生物,其製法及治療上的用途 - Google Patents
雜芳替代的洛衍生物,其製法及治療上的用途Info
- Publication number
- HK1047587A1 HK1047587A1 HK02108839.6A HK02108839A HK1047587A1 HK 1047587 A1 HK1047587 A1 HK 1047587A1 HK 02108839 A HK02108839 A HK 02108839A HK 1047587 A1 HK1047587 A1 HK 1047587A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- heteroaryl
- preparation
- therapeutic uses
- substituted pyrrole
- pyrrole derivates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP20549199 | 1999-07-21 | ||
JP36967899 | 1999-12-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1047587A1 true HK1047587A1 (zh) | 2003-02-28 |
Family
ID=26515088
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK02108839.6A HK1047587A1 (zh) | 1999-07-21 | 2001-06-19 | 雜芳替代的洛衍生物,其製法及治療上的用途 |
HK01104212A HK1033671A1 (en) | 1999-07-21 | 2001-06-19 | Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK01104212A HK1033671A1 (en) | 1999-07-21 | 2001-06-19 | Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses. |
Country Status (22)
Country | Link |
---|---|
EP (2) | EP1070711B1 (zh) |
KR (2) | KR100776958B1 (zh) |
CN (1) | CN1294129C (zh) |
AR (1) | AR024904A1 (zh) |
AT (1) | ATE264319T1 (zh) |
AU (1) | AU773453B2 (zh) |
BR (1) | BR0004534A (zh) |
CA (1) | CA2314373A1 (zh) |
DE (1) | DE60009804T2 (zh) |
DK (1) | DK1070711T3 (zh) |
ES (1) | ES2216826T3 (zh) |
HK (2) | HK1047587A1 (zh) |
HU (1) | HUP0002846A2 (zh) |
ID (1) | ID26611A (zh) |
IL (1) | IL137365A0 (zh) |
MX (1) | MXPA00007199A (zh) |
NO (1) | NO20003734L (zh) |
NZ (1) | NZ505924A (zh) |
PL (1) | PL341620A1 (zh) |
PT (1) | PT1070711E (zh) |
TR (1) | TR200002120A3 (zh) |
TW (1) | TWI259834B (zh) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPQ105499A0 (en) | 1999-06-18 | 1999-07-08 | Biota Scientific Management Pty Ltd | Antiviral agents |
US7122666B2 (en) | 1999-07-21 | 2006-10-17 | Sankyo Company, Limited | Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses |
EP1352906A4 (en) * | 2001-01-18 | 2004-06-16 | Sankyo Co | COMPOSITIONS FOR PREVENTION OR TREATMENT OF LIVER DISEASES |
DE60223339T2 (de) * | 2001-01-22 | 2008-08-28 | Sankyo Co., Ltd. | Durch bicyclische aminogruppen substituierte verbindungen |
EG23054A (en) * | 2001-01-22 | 2004-02-29 | Sankyo Co | Pyrrole derivatives their preparation and their therapeutic uses |
WO2002057255A1 (fr) * | 2001-01-22 | 2002-07-25 | Sankyo Company, Limited | Derives du pyrrole substitues en 4 ou 5 |
CA2437248A1 (en) * | 2001-02-02 | 2002-08-15 | Takeda Chemical Industries, Ltd. | Jnk inhibitor |
WO2002080974A1 (fr) * | 2001-04-04 | 2002-10-17 | Sankyo Company, Limited | Utilisation medicale d'inhibiteur de production de cytokine |
WO2002094267A1 (fr) * | 2001-05-24 | 2002-11-28 | Sankyo Company, Limited | Preparation pharmaceutique pour prevenir ou traiter l'arthrite |
WO2003015781A1 (fr) * | 2001-08-15 | 2003-02-27 | Sankyo Company, Limited | Nouvelles compositions pharmaceutiques antidiabetiques |
AU2003252212A1 (en) * | 2002-07-19 | 2004-02-09 | Sankyo Company, Limited | Bicyclic unsaturated tertiary amine compound |
US8809372B2 (en) | 2011-09-30 | 2014-08-19 | Asana Biosciences, Llc | Pyridine derivatives |
CA2850551A1 (en) * | 2011-09-30 | 2013-04-04 | Endo Pharmaceuticals Inc. | Pyridine derivatives |
US9630976B2 (en) | 2012-07-03 | 2017-04-25 | Ono Pharmaceutical Co., Ltd. | Compound having agonistic activity on somatostatin receptor, and use thereof for medical purposes |
WO2020113094A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5593992A (en) * | 1993-07-16 | 1997-01-14 | Smithkline Beecham Corporation | Compounds |
US5792778A (en) * | 1995-08-10 | 1998-08-11 | Merck & Co., Inc. | 2-substituted aryl pyrroles, compositions containing such compounds and methods of use |
EP0863757B1 (en) * | 1995-08-10 | 2003-03-26 | Merck & Co., Inc. | 2-substituted aryl pyrroles, compositions containing such compounds and methods of use |
-
2000
- 2000-07-18 IL IL13736500A patent/IL137365A0/xx unknown
- 2000-07-20 ES ES00306196T patent/ES2216826T3/es not_active Expired - Lifetime
- 2000-07-20 AT AT00306196T patent/ATE264319T1/de not_active IP Right Cessation
- 2000-07-20 TW TW089114563A patent/TWI259834B/zh not_active IP Right Cessation
- 2000-07-20 PT PT00306196T patent/PT1070711E/pt unknown
- 2000-07-20 DK DK00306196T patent/DK1070711T3/da active
- 2000-07-20 CA CA002314373A patent/CA2314373A1/en not_active Abandoned
- 2000-07-20 NO NO20003734A patent/NO20003734L/no not_active Application Discontinuation
- 2000-07-20 EP EP00306196A patent/EP1070711B1/en not_active Expired - Lifetime
- 2000-07-20 DE DE60009804T patent/DE60009804T2/de not_active Expired - Fee Related
- 2000-07-20 EP EP02011912A patent/EP1243589A1/en not_active Withdrawn
- 2000-07-21 ID IDP20000612A patent/ID26611A/id unknown
- 2000-07-21 NZ NZ505924A patent/NZ505924A/en unknown
- 2000-07-21 MX MXPA00007199A patent/MXPA00007199A/es unknown
- 2000-07-21 CN CNB001313037A patent/CN1294129C/zh not_active Expired - Fee Related
- 2000-07-21 KR KR1020000042064A patent/KR100776958B1/ko not_active IP Right Cessation
- 2000-07-21 PL PL00341620A patent/PL341620A1/xx unknown
- 2000-07-21 AR ARP000103779A patent/AR024904A1/es unknown
- 2000-07-21 BR BR0004534-9A patent/BR0004534A/pt not_active Application Discontinuation
- 2000-07-21 TR TR2000/02120A patent/TR200002120A3/tr unknown
- 2000-07-21 HU HU0002846A patent/HUP0002846A2/hu unknown
- 2000-07-21 AU AU48755/00A patent/AU773453B2/en not_active Ceased
-
2001
- 2001-06-19 HK HK02108839.6A patent/HK1047587A1/zh unknown
- 2001-06-19 HK HK01104212A patent/HK1033671A1/xx not_active IP Right Cessation
-
2007
- 2007-01-22 KR KR1020070006711A patent/KR20070026708A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR20010049843A (ko) | 2001-06-15 |
ES2216826T3 (es) | 2004-11-01 |
DE60009804T2 (de) | 2005-01-05 |
TWI259834B (en) | 2006-08-11 |
DK1070711T3 (da) | 2004-05-10 |
EP1070711B1 (en) | 2004-04-14 |
ID26611A (id) | 2001-01-25 |
NZ505924A (en) | 2001-11-30 |
HK1033671A1 (en) | 2001-09-14 |
EP1070711A3 (en) | 2001-01-31 |
ATE264319T1 (de) | 2004-04-15 |
AU4875500A (en) | 2001-02-01 |
PT1070711E (pt) | 2004-06-30 |
EP1070711A2 (en) | 2001-01-24 |
MXPA00007199A (es) | 2003-03-12 |
BR0004534A (pt) | 2001-02-28 |
AR024904A1 (es) | 2002-10-30 |
CN1294129C (zh) | 2007-01-10 |
CN1295069A (zh) | 2001-05-16 |
AU773453B2 (en) | 2004-05-27 |
IL137365A0 (en) | 2001-07-24 |
PL341620A1 (en) | 2001-01-29 |
DE60009804D1 (de) | 2004-05-19 |
CA2314373A1 (en) | 2001-01-21 |
KR100776958B1 (ko) | 2007-11-27 |
NO20003734D0 (no) | 2000-07-20 |
KR20070026708A (ko) | 2007-03-08 |
HU0002846D0 (en) | 2000-09-28 |
EP1243589A1 (en) | 2002-09-25 |
TR200002120A2 (tr) | 2001-06-21 |
TR200002120A3 (tr) | 2001-06-21 |
HUP0002846A2 (hu) | 2002-07-29 |
NO20003734L (no) | 2001-01-22 |
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