BG99074A - Recombinant human hiv neutralizing monoclonal antibodies for prophylaxy and treatment of hiv infection - Google Patents

Recombinant human hiv neutralizing monoclonal antibodies for prophylaxy and treatment of hiv infection

Info

Publication number
BG99074A
BG99074A BG99074A BG9907494A BG99074A BG 99074 A BG99074 A BG 99074A BG 99074 A BG99074 A BG 99074A BG 9907494 A BG9907494 A BG 9907494A BG 99074 A BG99074 A BG 99074A
Authority
BG
Bulgaria
Prior art keywords
treatment
recombinant human
prophylaxy
hiv
monoclonal antibodies
Prior art date
Application number
BG99074A
Other languages
Bulgarian (bg)
English (en)
Inventor
Emilio Emini
Anthony Conley
George Mark
L. Johnson
David Pfarr
Original Assignee
Merck & Co. Inc.
Medimmune,Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co. Inc., Medimmune,Inc. filed Critical Merck & Co. Inc.
Publication of BG99074A publication Critical patent/BG99074A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036Retroviridae, e.g. leukemia viruses
    • C07K16/1045Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • AIDS & HIV (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BG99074A 1992-04-01 1994-09-28 Recombinant human hiv neutralizing monoclonal antibodies for prophylaxy and treatment of hiv infection BG99074A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86170192A 1992-04-01 1992-04-01
PCT/US1993/002629 WO1993019785A1 (en) 1992-04-01 1993-03-23 Recombinant human hiv-neutralizing monoclonal antibodies for prevention and treatment of hiv infection

Publications (1)

Publication Number Publication Date
BG99074A true BG99074A (en) 1995-11-30

Family

ID=25336532

Family Applications (1)

Application Number Title Priority Date Filing Date
BG99074A BG99074A (en) 1992-04-01 1994-09-28 Recombinant human hiv neutralizing monoclonal antibodies for prophylaxy and treatment of hiv infection

Country Status (19)

Country Link
EP (1) EP0577243A3 (sk)
JP (1) JPH06217791A (sk)
KR (1) KR950700761A (sk)
CN (1) CN1081716A (sk)
AU (2) AU3928593A (sk)
BG (1) BG99074A (sk)
CA (1) CA2093099A1 (sk)
CZ (1) CZ239694A3 (sk)
FI (1) FI944561A (sk)
HU (1) HUT70461A (sk)
IL (1) IL105145A0 (sk)
MX (1) MX9301858A (sk)
NO (1) NO943653L (sk)
NZ (1) NZ251582A (sk)
RU (1) RU94045907A (sk)
SK (1) SK116294A3 (sk)
WO (1) WO1993019785A1 (sk)
YU (1) YU22693A (sk)
ZA (1) ZA932308B (sk)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2348938A1 (en) * 1998-10-30 2000-05-11 Novozymes A/S Low allergenic protein variants
US7560529B2 (en) 2001-04-24 2009-07-14 FDS Pharma Method for producing catalytic antibodies (variants), antigens for immunization and nucleotide sequence
RU2221873C2 (ru) * 2001-04-24 2004-01-20 Закрытое акционерное общество "АСГЛ-Фармацевтические Инновации" Способ получения каталитических антител (варианты), антигены для иммунизации и нуклеотидная последовательность
FR2844455B1 (fr) * 2002-09-13 2007-12-14 Lab Francais Du Fractionnement Traitement des pathologies echappant a la reponse immune par des anticorps optimises
JP4922613B2 (ja) * 2003-02-20 2012-04-25 一般財団法人化学及血清療法研究所 モノクローナル抗体製剤の奏効性を向上させる方法
BRPI0815743A2 (pt) * 2007-08-24 2015-02-18 Novartis Ag Proteínas hiv env com modificações no laço v3
PT2364314E (pt) 2008-12-09 2014-06-09 Gilead Sciences Inc Moduladores de recetores toll-like
US10421803B2 (en) 2014-01-31 2019-09-24 The Rockefeller University Broadly neutralizing glycan-dependent 8ANC195 antibody variants that bind to an epitope spanning both HIV-1 Env subunits
EP4140485A1 (en) * 2014-07-11 2023-03-01 Gilead Sciences, Inc. Modulators of toll-like receptors for the treatment of hiv
SG11201701520TA (en) 2014-09-16 2017-04-27 Gilead Sciences Inc Solid forms of a toll-like receptor modulator
WO2021227138A1 (zh) * 2020-05-09 2021-11-18 江苏省疾病预防控制中心(江苏省公共卫生研究院) 针对新型冠状病毒的单克隆抗体或其抗原结合部分

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988009181A2 (en) * 1987-05-29 1988-12-01 Tanox Biosystems, Inc. Monoclonal antibodies neutralizing hiv-1
EP0311228A3 (en) * 1987-10-09 1990-05-02 Repligen Corporation Recombinant polypeptides and their uses, including assay for aids virus
PT94276A (pt) * 1989-06-05 1991-02-08 Anticorpo monoclonal capaz de neutralizar o prototipo mn de hiv
CA2087347C (en) * 1990-06-15 2004-03-30 Susan Zolla-Pazner Heterohybridomas producing human monoclonal antibodies to hiv-1
JPH07505051A (ja) * 1992-01-29 1995-06-08 アメリカ合衆国 Hiv−1env及びnefタンパク質に対して局部的相同性を有するタンパク質,aamp−1

Also Published As

Publication number Publication date
RU94045907A (ru) 1996-11-10
JPH06217791A (ja) 1994-08-09
NO943653D0 (no) 1994-09-30
FI944561A0 (fi) 1994-09-30
EP0577243A3 (en) 1994-11-02
MX9301858A (es) 1994-03-31
YU22693A (sh) 1997-01-08
NZ251582A (en) 1997-07-27
CZ239694A3 (en) 1995-07-12
AU658987B2 (en) 1995-05-04
HU9402824D0 (en) 1994-11-28
HUT70461A (en) 1995-10-30
SK116294A3 (en) 1996-11-06
IL105145A0 (en) 1993-07-08
FI944561A (fi) 1994-09-30
CN1081716A (zh) 1994-02-09
AU3928593A (en) 1993-11-08
EP0577243A2 (en) 1994-01-05
CA2093099A1 (en) 1993-10-02
WO1993019785A1 (en) 1993-10-14
NO943653L (no) 1994-11-30
ZA932308B (en) 1994-09-30
AU3563093A (en) 1993-10-07
KR950700761A (ko) 1995-02-20

Similar Documents

Publication Publication Date Title
SE8703225L (sv) Monoklonala antikroppar och peptider anvendbara vid behandling och diagnostisering av hiv-infektioner
KR950005327A (ko) 임파구 항원 CD2 및 종양 항원을 인식하는 이특이적 트리거(Trigger) 분자
FR12C0004I2 (fr) Anticorps contre l'antigene ctla-4 humain et utilisation
DK0626447T3 (da) Monoklonale antistoffer og Fv, som er specifikke for CD2-antigen
DK1140170T3 (da) Antistoffragmenter til topisk behandling af öjensygdomme
ATE122237T1 (de) Hiv-1 neutralisierende monoklonale antikörper.
AR045056A1 (es) Anticuerpos anti-ngf humanos neutralizantes como inhibidores selectivos de la via de ngf
BG99074A (en) Recombinant human hiv neutralizing monoclonal antibodies for prophylaxy and treatment of hiv infection
DE69609188D1 (de) Neutralisierende monoklonale antikörper gegen respiratorischen synzytialvirus
DK442688A (da) Fremgangsmaade og praeparat til behandling af non-ige-medierede lidelser
EA200601715A1 (ru) Получение гуманизированных антител в [организме] трансгенных животных
DK0702563T3 (da) Sammensætninger og fremgangsmåder til behandling af cancer og hyperproliferative sygdomme
BR9607171A (pt) Anticorpos monoclonais anti-cd6 e usos dos mesmos
DK0552296T3 (da) Monoklonale antistoffer fra mus
EA200401081A1 (ru) Fab-фрагменты моноклонального антитела человека, направленные против гликопротеина e2 hcv и обладающие нейтрализующей активностью in vitro
MC2308A1 (fr) Peptides utilises dans la vaccination et l'induction d'anticorps neutralisant contre le virus de l'immunodeficience humaine
DE69737323D1 (de) Adhesin aus heliobacter pylori, welches an blutgruppenantigene bindet
FI934145A (fi) Omformade monoklonala antikroppar mot en immunoglobulinisotyp
DE69841331D1 (de) Humanisierte monoklonale antikörper die schützen gegen shigatoxininduzierte krankheiten
BG96346A (bg) Специфични свързващи вещества
SG128482A1 (en) Method and composition for altering a b cell mediated pathology
ATE75754T1 (de) Monoklonale antikoerper gegen atriale, natriurethische peptide.
KR890016165A (ko) 수도모나스 아에루기노사(Pseudomonas aeruginosa)에 대한 모노클로날 항체, 이의 제조방법 및 용도
RU2217166C2 (ru) Гуманизированные антитела, которые распознают веротоксин ii, и продуцирующая их линия клеток
FI92716C (fi) Uudet monoklonaaliset vasta-aineet IFN-omegalle, niiden valmistusmenetelmät ja niiden käyttö IFN-omegan puhdistamiseen ja osoittamiseen