MX9301858A - Anticuerpos monoclonales neutralizantes de hiv-humano recombinante para prevencion y tratamiento de infeccion hiv. - Google Patents

Anticuerpos monoclonales neutralizantes de hiv-humano recombinante para prevencion y tratamiento de infeccion hiv.

Info

Publication number
MX9301858A
MX9301858A MX9301858A MX9301858A MX9301858A MX 9301858 A MX9301858 A MX 9301858A MX 9301858 A MX9301858 A MX 9301858A MX 9301858 A MX9301858 A MX 9301858A MX 9301858 A MX9301858 A MX 9301858A
Authority
MX
Mexico
Prior art keywords
hiv
prevention
treatment
monoclonal antibodies
neutralizing monoclonal
Prior art date
Application number
MX9301858A
Other languages
English (en)
Inventor
L Syd Johnson
David S Pfarr
Emilio A Emini
Anthony J Conley
Geroge E Mark
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of MX9301858A publication Critical patent/MX9301858A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • AIDS & HIV (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Se describen moléculas de inmunoglobulina humana recombinantes que neutralizan para HIV-1, métodos para producir las inmunoglobulinas y métodos para evitar la infección de HIV-1 empleando las inmunoglobulinas.
MX9301858A 1992-04-01 1993-03-31 Anticuerpos monoclonales neutralizantes de hiv-humano recombinante para prevencion y tratamiento de infeccion hiv. MX9301858A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86170192A 1992-04-01 1992-04-01

Publications (1)

Publication Number Publication Date
MX9301858A true MX9301858A (es) 1994-03-31

Family

ID=25336532

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9301858A MX9301858A (es) 1992-04-01 1993-03-31 Anticuerpos monoclonales neutralizantes de hiv-humano recombinante para prevencion y tratamiento de infeccion hiv.

Country Status (19)

Country Link
EP (1) EP0577243A3 (es)
JP (1) JPH06217791A (es)
KR (1) KR950700761A (es)
CN (1) CN1081716A (es)
AU (2) AU3928593A (es)
BG (1) BG99074A (es)
CA (1) CA2093099A1 (es)
CZ (1) CZ239694A3 (es)
FI (1) FI944561A0 (es)
HU (1) HUT70461A (es)
IL (1) IL105145A0 (es)
MX (1) MX9301858A (es)
NO (1) NO943653L (es)
NZ (1) NZ251582A (es)
RU (1) RU94045907A (es)
SK (1) SK116294A3 (es)
WO (1) WO1993019785A1 (es)
YU (1) YU22693A (es)
ZA (1) ZA932308B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2220114T3 (es) * 1998-10-30 2004-12-01 Novozymes A/S Variantes de proteinas poco alergenicas.
US7560529B2 (en) 2001-04-24 2009-07-14 FDS Pharma Method for producing catalytic antibodies (variants), antigens for immunization and nucleotide sequence
RU2221873C2 (ru) * 2001-04-24 2004-01-20 Закрытое акционерное общество "АСГЛ-Фармацевтические Инновации" Способ получения каталитических антител (варианты), антигены для иммунизации и нуклеотидная последовательность
FR2844455B1 (fr) * 2002-09-13 2007-12-14 Lab Francais Du Fractionnement Traitement des pathologies echappant a la reponse immune par des anticorps optimises
PT1595959E (pt) * 2003-02-20 2015-03-05 Chemo Sero Therapeut Res Inst Método para melhorar a eficácia de uma preparação de anticorpo monoclonal
BRPI0815743A2 (pt) * 2007-08-24 2015-02-18 Novartis Ag Proteínas hiv env com modificações no laço v3
EP2364314B1 (en) 2008-12-09 2014-03-12 Gilead Sciences, Inc. Modulators of toll-like receptors
US10421803B2 (en) 2014-01-31 2019-09-24 The Rockefeller University Broadly neutralizing glycan-dependent 8ANC195 antibody variants that bind to an epitope spanning both HIV-1 Env subunits
NZ728072A (en) 2014-07-11 2018-06-29 Gilead Sciences Inc Modulators of toll-like receptors for the treatment of hiv
JP2017526730A (ja) 2014-09-16 2017-09-14 ギリアード サイエンシーズ， インコーポレイテッド Ｔｏｌｌ様受容体モジュレーターの固体形態
WO2021227138A1 (zh) * 2020-05-09 2021-11-18 江苏省疾病预防控制中心(江苏省公共卫生研究院) 针对新型冠状病毒的单克隆抗体或其抗原结合部分

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3853779T2 (de) * 1987-05-29 1995-09-07 Tanox Biosystems Inc Hiv-1 neutralisierende monoklonale antikörper.
EP0311228A3 (en) * 1987-10-09 1990-05-02 Repligen Corporation Recombinant polypeptides and their uses, including assay for aids virus
AU6036690A (en) * 1989-06-05 1991-01-07 Helen F. Carson Human monoclonal antibodies to hiv-1mn gp 120
AU8228791A (en) * 1990-06-15 1992-01-07 New York University Heterohybridomas producing human monoclonal antibodies to hiv-1
CA2128879A1 (en) * 1992-01-29 1993-08-05 Marie E. Beckner Aamp-1, a protein with local homologies to hiv-1 env and nef proteins

Also Published As

Publication number Publication date
EP0577243A2 (en) 1994-01-05
NZ251582A (en) 1997-07-27
NO943653D0 (no) 1994-09-30
AU3928593A (en) 1993-11-08
SK116294A3 (en) 1996-11-06
RU94045907A (ru) 1996-11-10
KR950700761A (ko) 1995-02-20
WO1993019785A1 (en) 1993-10-14
IL105145A0 (en) 1993-07-08
CA2093099A1 (en) 1993-10-02
HUT70461A (en) 1995-10-30
CZ239694A3 (en) 1995-07-12
YU22693A (sh) 1997-01-08
EP0577243A3 (en) 1994-11-02
JPH06217791A (ja) 1994-08-09
ZA932308B (en) 1994-09-30
BG99074A (en) 1995-11-30
HU9402824D0 (en) 1994-11-28
NO943653L (no) 1994-11-30
AU658987B2 (en) 1995-05-04
CN1081716A (zh) 1994-02-09
FI944561A (fi) 1994-09-30
FI944561A0 (fi) 1994-09-30
AU3563093A (en) 1993-10-07

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