BG64556B1 - Кондензирани с арил азаполициклични съединения - Google Patents

Кондензирани с арил азаполициклични съединения Download PDF

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Publication number
BG64556B1
BG64556B1 BG104983A BG10498300A BG64556B1 BG 64556 B1 BG64556 B1 BG 64556B1 BG 104983 A BG104983 A BG 104983A BG 10498300 A BG10498300 A BG 10498300A BG 64556 B1 BG64556 B1 BG 64556B1
Authority
BG
Bulgaria
Prior art keywords
triene
trideca
alkyl
tetraene
hexadeca
Prior art date
Application number
BG104983A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG104983A (en
Inventor
Jotham Coe
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of BG104983A publication Critical patent/BG104983A/xx
Publication of BG64556B1 publication Critical patent/BG64556B1/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
BG104983A 1998-04-29 2000-11-24 Кондензирани с арил азаполициклични съединения BG64556B1 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8355698P 1998-04-29 1998-04-29

Publications (2)

Publication Number Publication Date
BG104983A BG104983A (en) 2001-09-28
BG64556B1 true BG64556B1 (bg) 2005-07-29

Family

ID=22179102

Family Applications (1)

Application Number Title Priority Date Filing Date
BG104983A BG64556B1 (bg) 1998-04-29 2000-11-24 Кондензирани с арил азаполициклични съединения

Country Status (42)

Country Link
US (3) US6462035B1 (fr)
EP (1) EP1076650B1 (fr)
JP (1) JP2002513007A (fr)
KR (1) KR100420423B1 (fr)
CN (1) CN1144787C (fr)
AP (1) AP1154A (fr)
AR (1) AR018596A1 (fr)
AT (1) ATE258921T1 (fr)
AU (1) AU749831B2 (fr)
BG (1) BG64556B1 (fr)
BR (1) BR9910058A (fr)
CA (1) CA2330576A1 (fr)
CO (1) CO5021124A1 (fr)
DE (1) DE69914594T2 (fr)
DK (1) DK1076650T3 (fr)
DZ (1) DZ2778A1 (fr)
EA (1) EA003669B1 (fr)
ES (1) ES2213354T3 (fr)
GT (1) GT199900059A (fr)
HK (1) HK1036453A1 (fr)
HR (1) HRP20000731A2 (fr)
HU (1) HUP0103340A3 (fr)
ID (1) ID26700A (fr)
IL (1) IL138917A0 (fr)
IS (1) IS5649A (fr)
MA (1) MA26623A1 (fr)
MY (1) MY133474A (fr)
NO (1) NO317300B1 (fr)
NZ (1) NZ507035A (fr)
OA (1) OA11506A (fr)
PA (1) PA8471301A1 (fr)
PE (1) PE20000435A1 (fr)
PL (1) PL344010A1 (fr)
PT (1) PT1076650E (fr)
SK (1) SK15952000A3 (fr)
TN (1) TNSN99080A1 (fr)
TR (1) TR200003122T2 (fr)
UA (1) UA61991C2 (fr)
UY (1) UY25636A1 (fr)
WO (1) WO1999055680A1 (fr)
YU (1) YU64400A (fr)
ZA (1) ZA992971B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6605610B1 (en) 1997-12-31 2003-08-12 Pfizer Inc Aryl fused azapolycyclic compounds
ES2301210T5 (es) 1997-12-31 2015-05-07 Pfizer Products Inc. Compuestos azapolicíclicos condensados con un arilo
US20010036943A1 (en) * 2000-04-07 2001-11-01 Coe Jotham W. Pharmaceutical composition for treatment of acute, chronic pain and/or neuropathic pain and migraines
IL157881A0 (en) * 2001-04-20 2004-03-28 Pfizer Prod Inc Process for the preparation of 1,3-substituted indenes and aryl-fused azapolycyclic compounds
WO2003037329A1 (fr) * 2001-10-31 2003-05-08 Pfizer Products Inc. Agonistes du recepteur d'acetylcholine nicotinique pour traiter les impatiences des membres inferieurs
DE60228478D1 (de) 2001-11-30 2008-10-02 Pfizer Prod Inc Aryl-annellierte azapolyzyklische verbindungen
WO2003093258A2 (fr) * 2002-05-03 2003-11-13 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Nouveaux derives de spirocetone et d'acide carboxylique utilises comme inhibiteurs specifiques de (po3h2)ser/(po3h2)thr-pro-specifique peptidyl-prolyl-cis/trans-isomerases
US20040224962A1 (en) * 2003-05-09 2004-11-11 Pfizer Inc Pharmaceutical composition for the treatment of obesity or to facilitate or promote weight loss
US20040224963A1 (en) * 2003-05-09 2004-11-11 Pfizer Inc Pharmaceutical composition for the prevention and treatment of nicotine addiction in a mammal
BRPI0412880A (pt) * 2003-07-21 2006-10-03 Pfizer Prod Inc compostos azapolicìclicos fundidos a arila
EP1648893B1 (fr) 2003-07-21 2009-09-23 Pfizer Products Inc. Composes azapolycycliques fusionnes avec heteroaryle pour reduire la dependance a la nicotine
US20050043407A1 (en) * 2003-08-22 2005-02-24 Pfizer Inc Pharmaceutical composition for the prevention and treatment of addiction in a mammal
ATE395348T1 (de) * 2004-12-07 2008-05-15 Pfizer Prod Inc 1,2,3,3a;8,8a-hexahydro-2,7a- diazacyclopenta(a)inden-7-onderivate, die sich an neuronale nikotinische acetylcholinspezifische rezeptorstellen binden und zur modulation der cholinergen funktion und zur behandlung von suchterkrankungen eignen
US20060210497A1 (en) * 2005-03-18 2006-09-21 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Novel resorcinol derivatives
US20060210498A1 (en) 2005-03-18 2006-09-21 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Novel resorcinol derivatives for skin
DE102005061426A1 (de) * 2005-12-22 2007-07-05 Grünenthal GmbH Substituierte tricyclische Piperidon-Derivate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3687937A (en) * 1970-06-23 1972-08-29 Us Of America The 1,5-methano-3-benzazocine derivatives
JPS4914473A (fr) * 1972-06-09 1974-02-07
JPS4924968A (fr) * 1972-07-01 1974-03-05

Also Published As

Publication number Publication date
DZ2778A1 (fr) 2005-04-23
IS5649A (is) 2000-09-29
US20040167149A1 (en) 2004-08-26
EP1076650A1 (fr) 2001-02-21
MA26623A1 (fr) 2004-12-20
PT1076650E (pt) 2004-05-31
NO317300B1 (no) 2004-10-04
KR20010043143A (ko) 2001-05-25
DE69914594D1 (de) 2004-03-11
KR100420423B1 (ko) 2004-03-04
IL138917A0 (en) 2001-11-25
ZA992971B (en) 2000-10-30
US6706702B2 (en) 2004-03-16
GT199900059A (es) 2000-10-11
HRP20000731A2 (en) 2001-06-30
PE20000435A1 (es) 2000-05-26
EP1076650B1 (fr) 2004-02-04
ES2213354T3 (es) 2004-08-16
EA200000996A1 (ru) 2001-06-25
MY133474A (en) 2007-11-30
AP9901524A0 (en) 1999-06-30
TR200003122T2 (tr) 2001-03-21
CA2330576A1 (fr) 1999-11-04
AU749831B2 (en) 2002-07-04
CN1298394A (zh) 2001-06-06
EA003669B1 (ru) 2003-08-28
CO5021124A1 (es) 2001-03-27
JP2002513007A (ja) 2002-05-08
DE69914594T2 (de) 2004-12-09
US6462035B1 (en) 2002-10-08
NO20005397D0 (no) 2000-10-26
BR9910058A (pt) 2000-12-26
HK1036453A1 (en) 2002-01-04
UA61991C2 (en) 2003-12-15
SK15952000A3 (sk) 2002-06-04
US7122534B2 (en) 2006-10-17
WO1999055680A1 (fr) 1999-11-04
HUP0103340A2 (hu) 2002-02-28
NO20005397L (no) 2000-10-26
OA11506A (en) 2004-05-14
US20030008890A1 (en) 2003-01-09
HUP0103340A3 (en) 2002-10-28
AP1154A (en) 2003-03-27
AU2951699A (en) 1999-11-16
DK1076650T3 (da) 2004-05-24
ID26700A (id) 2001-02-01
TNSN99080A1 (fr) 2005-11-10
ATE258921T1 (de) 2004-02-15
PL344010A1 (en) 2001-09-24
PA8471301A1 (es) 2000-09-29
YU64400A (sh) 2003-01-31
UY25636A1 (es) 2000-02-23
BG104983A (en) 2001-09-28
AR018596A1 (es) 2001-11-28
CN1144787C (zh) 2004-04-07
NZ507035A (en) 2003-05-30

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