BG64367B1 - Метод за получаване на воден фармацевтичен състав - Google Patents

Метод за получаване на воден фармацевтичен състав Download PDF

Info

Publication number
BG64367B1
BG64367B1 BG103739A BG10373999A BG64367B1 BG 64367 B1 BG64367 B1 BG 64367B1 BG 103739 A BG103739 A BG 103739A BG 10373999 A BG10373999 A BG 10373999A BG 64367 B1 BG64367 B1 BG 64367B1
Authority
BG
Bulgaria
Prior art keywords
weight
active substance
liposomes
aqueous
phase
Prior art date
Application number
BG103739A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG103739A (en
Inventor
Giovanni Cavallo
Leonardo Marchitto
Original Assignee
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. filed Critical Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A.
Publication of BG103739A publication Critical patent/BG103739A/xx
Publication of BG64367B1 publication Critical patent/BG64367B1/bg

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1277Processes for preparing; Proliposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906Drug delivery
    • Y10S977/907Liposome

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BG103739A 1997-02-20 1999-09-16 Метод за получаване на воден фармацевтичен състав BG64367B1 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI000363A IT1289939B1 (it) 1997-02-20 1997-02-20 Composizione farmaceutica acquosa comprendente un principio attivo altamente insolubile in acqua

Publications (2)

Publication Number Publication Date
BG103739A BG103739A (en) 2000-06-30
BG64367B1 true BG64367B1 (bg) 2004-12-30

Family

ID=11376099

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103739A BG64367B1 (bg) 1997-02-20 1999-09-16 Метод за получаване на воден фармацевтичен състав

Country Status (26)

Country Link
US (1) US6337087B1 (it)
EP (1) EP0973505B1 (it)
JP (1) JP4299369B2 (it)
KR (1) KR100515249B1 (it)
CN (1) CN1135969C (it)
AR (1) AR011682A1 (it)
AT (1) ATE257374T1 (it)
AU (1) AU740619B2 (it)
BG (1) BG64367B1 (it)
CA (1) CA2285985C (it)
CZ (1) CZ296700B6 (it)
DE (1) DE69821001T2 (it)
DK (1) DK0973505T3 (it)
EA (1) EA002281B1 (it)
ES (1) ES2213894T3 (it)
GE (1) GEP20022751B (it)
HU (1) HU225594B1 (it)
IL (2) IL131354A0 (it)
IT (1) IT1289939B1 (it)
PL (1) PL190987B1 (it)
PT (1) PT973505E (it)
SK (1) SK282905B6 (it)
TR (1) TR199901987T2 (it)
UA (1) UA63939C2 (it)
WO (1) WO1998036735A1 (it)
ZA (1) ZA981354B (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9804192D0 (sv) * 1998-12-03 1998-12-03 Scotia Lipidteknik Ab New formulation
US6075045A (en) * 1999-04-28 2000-06-13 Ajinomoto Co., Inc. Method of treating paralysis of the extremities caused by cerebral infarction
JP4894119B2 (ja) * 2001-09-26 2012-03-14 日油株式会社 脂肪酸含有リポソーム分散液
US20040115226A1 (en) * 2002-12-12 2004-06-17 Wenji Li Free-flowing solid formulations with improved bio-availability of poorly water soluble drugs and process for making the same
WO2004064736A2 (en) * 2003-01-17 2004-08-05 Threshold Pharmaceuticals, Inc. Treatment of benign prostatic hyperplasia using energolytic agents
US20050238675A1 (en) * 2004-04-26 2005-10-27 Wenjie Li Water-soluble formulations of fat soluble vitamins and pharmaceutical agents and their applications
US8999292B2 (en) 2012-05-01 2015-04-07 Translatum Medicus Inc. Methods for treating and diagnosing blinding eye diseases
US20210290562A1 (en) * 2018-12-11 2021-09-23 Disruption Labs Inc. Compositions for the delivery of therapeutic agents and methods of use and making thereof
CN111759807B (zh) * 2019-04-01 2021-06-01 上海谷森医药有限公司 一种环孢素脂质体及其制备方法
CA3144861A1 (en) 2019-06-25 2020-12-30 Translatum Medicus, Inc. Processes of making 2-((1-benzyl-1h-indazol-3-yl)methoxy)-2-methylpropanoic acid and its derivatives

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4038075C1 (en) * 1990-11-29 1992-03-19 B. Braun Melsungen Ag, 3508 Melsungen, De Encapsulating solid or liq. lipophilic agents - comprises mixing hydration medium with phospholipid increasing temp. to above soln. phase change temp. and adding remaining medium
EP0578629A1 (de) * 1992-07-09 1994-01-12 ÖSKO, Österreichische Säurebau- und Korrosionsschutz Gesellschaft mbH Verfahren zum Reinigen eines Rauchgasstromes mit Hilfe einer Waschflüssigkeit
DE4430593A1 (de) * 1994-08-20 1996-02-22 Max Delbrueck Centrum Liposomal verkapseltes Taxol, seine Herstellung und seine Verwendung
WO1996040064A1 (en) * 1995-06-07 1996-12-19 Nexstar Pharmaceuticals, Inc. Liposomal cyclosporin formulations as agents for immunosuppression and multiple drug resistant indications

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1264668C (en) * 1984-06-20 1990-01-23 EXTRUSION TECHNIQUES FOR THE PRODUCTION OF LIPOSOMES
IT1254995B (it) * 1992-06-24 1995-10-11 Farmaco contenente melatonina e/o agonisti, con somministrazione particolarmente efficace nelle patologie che interferiscono con i ritmi circandiani
FR2716110B1 (fr) * 1994-02-16 1996-04-05 Roussel Uclaf Compositions cosmétiques ou pharmaceutiques comprenant des liposomes.

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4038075C1 (en) * 1990-11-29 1992-03-19 B. Braun Melsungen Ag, 3508 Melsungen, De Encapsulating solid or liq. lipophilic agents - comprises mixing hydration medium with phospholipid increasing temp. to above soln. phase change temp. and adding remaining medium
EP0578629A1 (de) * 1992-07-09 1994-01-12 ÖSKO, Österreichische Säurebau- und Korrosionsschutz Gesellschaft mbH Verfahren zum Reinigen eines Rauchgasstromes mit Hilfe einer Waschflüssigkeit
DE4430593A1 (de) * 1994-08-20 1996-02-22 Max Delbrueck Centrum Liposomal verkapseltes Taxol, seine Herstellung und seine Verwendung
WO1996040064A1 (en) * 1995-06-07 1996-12-19 Nexstar Pharmaceuticals, Inc. Liposomal cyclosporin formulations as agents for immunosuppression and multiple drug resistant indications

Also Published As

Publication number Publication date
US6337087B1 (en) 2002-01-08
BG103739A (en) 2000-06-30
DE69821001T2 (de) 2004-11-11
WO1998036735A1 (en) 1998-08-27
TR199901987T2 (xx) 1999-11-22
CN1135969C (zh) 2004-01-28
HUP0000910A2 (hu) 2000-10-28
KR100515249B1 (ko) 2005-09-16
UA63939C2 (uk) 2004-02-16
AU6398798A (en) 1998-09-09
SK111199A3 (en) 2000-06-12
SK282905B6 (sk) 2003-01-09
ATE257374T1 (de) 2004-01-15
IT1289939B1 (it) 1998-10-19
CA2285985C (en) 2008-01-29
ZA981354B (en) 1998-08-17
CN1255057A (zh) 2000-05-31
JP2001519775A (ja) 2001-10-23
EP0973505A1 (en) 2000-01-26
EA002281B1 (ru) 2002-02-28
EP0973505B1 (en) 2004-01-07
JP4299369B2 (ja) 2009-07-22
CZ292699A3 (cs) 2000-01-12
IL131354A0 (en) 2001-01-28
CA2285985A1 (en) 1998-08-27
PL335208A1 (en) 2000-04-10
KR20000075480A (ko) 2000-12-15
ES2213894T3 (es) 2004-09-01
PL190987B1 (pl) 2006-02-28
PT973505E (pt) 2004-05-31
IL131354A (en) 2010-06-30
DK0973505T3 (da) 2004-05-03
GEP20022751B (en) 2002-08-26
CZ296700B6 (cs) 2006-05-17
HU225594B1 (en) 2007-05-02
DE69821001D1 (de) 2004-02-12
AU740619B2 (en) 2001-11-08
AR011682A1 (es) 2000-08-30
ITMI970363A1 (it) 1998-08-20
EA199900750A1 (ru) 2000-04-24
HUP0000910A3 (en) 2000-11-28

Similar Documents

Publication Publication Date Title
US5616334A (en) Low toxicity drug-lipid systems
US6406713B1 (en) Methods of preparing low-toxicity drug-lipid complexes
US4761288A (en) Multiphase liposomal drug delivery system
US4897269A (en) Administration of drugs with multiphase liposomal delivery system
RU2216315C2 (ru) Способ получения липосом
JP2911814B2 (ja) リポソーム性の水中分散する経口投与可能な固体乾燥治療用処方の製造方法
EP0177223B1 (en) Pharmaceutical multi-phase composition
JPS6339810A (ja) リポソ−ムの製造法
EP0282405B2 (en) Low toxicity drug-lipid systems
JP2574309B2 (ja) 一様な二重層化されたリポソームの製造法
CA2162341A1 (en) Pharmaceutical carriers
BG64580B1 (bg) Фармацевтичен състав, съдържащ лиофилизирани липозоми, включващи трудно разтворимо във вода активно вещество и метод за получаването на този състав
BG64367B1 (bg) Метод за получаване на воден фармацевтичен състав
US5173219A (en) Uniform spherical multilamellar liposomes of defined and adjustable size distribution
JPH0824840B2 (ja) サブミクロン大リポソームの形態の両親媒性脂質の分散性コロイド系の調製方法
US20020119170A1 (en) Low toxicity drug-lipid systems
CN100431525C (zh) 脂质体悬浮液制造方法及含该法所制脂质体悬浮液的产物
MXPA99007683A (en) Aqueous pharmaceutical composition comprising an active ingredient which is highly insoluble in water