BG63502B1 - Заместени арилалкилтио-алкилтиопиридини и използване за борба с бактерии от рода helicobacter - Google Patents
Заместени арилалкилтио-алкилтиопиридини и използване за борба с бактерии от рода helicobacter Download PDFInfo
- Publication number
- BG63502B1 BG63502B1 BG101002A BG10100296A BG63502B1 BG 63502 B1 BG63502 B1 BG 63502B1 BG 101002 A BG101002 A BG 101002A BG 10100296 A BG10100296 A BG 10100296A BG 63502 B1 BG63502 B1 BG 63502B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- alkyl
- hydrogen
- compounds
- methyl
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH184594 | 1994-06-10 | ||
| PCT/EP1995/002237 WO1995034554A1 (de) | 1994-06-10 | 1995-06-09 | Substituierte arylalkylthioalkylthiopyridine zur bekämpfung von helicobacter-bakterien |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG101002A BG101002A (en) | 1997-08-29 |
| BG63502B1 true BG63502B1 (bg) | 2002-03-29 |
Family
ID=4219963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG101002A BG63502B1 (bg) | 1994-06-10 | 1996-11-21 | Заместени арилалкилтио-алкилтиопиридини и използване за борба с бактерии от рода helicobacter |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5859030A (pl) |
| EP (1) | EP0764161A1 (pl) |
| JP (1) | JPH10501254A (pl) |
| CN (1) | CN1070488C (pl) |
| AU (1) | AU697572B2 (pl) |
| BG (1) | BG63502B1 (pl) |
| CA (1) | CA2192202A1 (pl) |
| CZ (1) | CZ288079B6 (pl) |
| EE (1) | EE03312B1 (pl) |
| FI (1) | FI964909A0 (pl) |
| HK (1) | HK1001957A1 (pl) |
| HU (1) | HU220062B (pl) |
| MX (1) | MX9606300A (pl) |
| NO (1) | NO311618B1 (pl) |
| NZ (1) | NZ288609A (pl) |
| PL (1) | PL181801B1 (pl) |
| RO (1) | RO117792B1 (pl) |
| RU (1) | RU2139286C1 (pl) |
| SK (1) | SK281465B6 (pl) |
| WO (1) | WO1995034554A1 (pl) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997019593A1 (en) * | 1995-11-28 | 1997-06-05 | Wider Michael D | Antimicrobial composition and methods of use therefor |
| EP1086094A1 (en) * | 1998-05-23 | 2001-03-28 | Byk Gulden Lomberg Chemische Fabrik GmbH | Quinoline-aminomethyl-pyridyl derivatives with anti-helicobacter activity |
| WO2000050037A1 (en) * | 1999-02-26 | 2000-08-31 | Nitromed, Inc. | Nitrosated and nitrosylated proton pump inhibitors, compositions and methods of use |
| US6262085B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
| US6326384B1 (en) | 1999-08-26 | 2001-12-04 | Robert R. Whittle | Dry blend pharmaceutical unit dosage form |
| US6262086B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Pharmaceutical unit dosage form |
| US6780880B1 (en) | 1999-08-26 | 2004-08-24 | Robert R. Whittle | FT-Raman spectroscopic measurement |
| US6312712B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Method of improving bioavailability |
| US6268385B1 (en) | 1999-08-26 | 2001-07-31 | Robert R. Whittle | Dry blend pharmaceutical formulations |
| US6369087B1 (en) | 1999-08-26 | 2002-04-09 | Robert R. Whittle | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
| US6316020B1 (en) | 1999-08-26 | 2001-11-13 | Robert R. Whittle | Pharmaceutical formulations |
| US6312723B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Pharmaceutical unit dosage form |
| AU2003259154B2 (en) * | 2002-07-19 | 2006-12-07 | The Regents Of The University Of California | Benzimidazole derivatives and their use as prodrugs of proton pump inhibitor |
| US20100317689A1 (en) * | 2006-09-19 | 2010-12-16 | Garst Michael E | Prodrugs of proton pump inhibitors including the 1h-imidazo[4,5-b] pyridine moiety |
| RU2449805C1 (ru) | 2011-01-27 | 2012-05-10 | Общество С Ограниченной Ответственностью "Гармония" | Пептидная фармацевтическая композиция, средство на ее основе для лечения гастродуоденальных заболеваний, вызываемых helicobacter pylori, и способ его использования |
| CN110294751B (zh) * | 2018-03-21 | 2020-11-20 | 湖南化工研究院有限公司 | 具生物活性的咪唑[4,5-b]并吡啶类化合物及其制备方法和应用 |
| CN110156752B (zh) * | 2019-05-28 | 2021-03-19 | 沈阳药科大学 | 2-[(吡啶-2-基甲基)硫基]-1h-苯并咪唑类化合物及应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1234058A (pl) * | 1968-10-21 | 1971-06-03 | ||
| JPS604826B2 (ja) * | 1978-09-12 | 1985-02-06 | 藤沢薬品工業株式会社 | インダゾ−ル酢酸類の製造法 |
| US4387225A (en) * | 1981-01-15 | 1983-06-07 | William H. Rorer, Inc. | Heterocyclic alkylene triazinones |
| JPS57200386A (en) * | 1981-06-04 | 1982-12-08 | Yoshitomi Pharmaceut Ind Ltd | Novel 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its salts |
| HU191756B (en) * | 1983-05-03 | 1987-04-28 | Byk Gulden Lomberg Chem Fab | Process for preparing new fluoro-alkoxy-benzimidazole derivatives |
| JP2563619B2 (ja) * | 1989-11-28 | 1996-12-11 | 株式会社東芝 | ダクト用換気扇 |
| US5504082A (en) * | 1992-06-01 | 1996-04-02 | Yoshitomi Pharmaceutical Industries, Ltd. | Pyridine compound and pharmaceutical compostions |
| CA2136993A1 (en) * | 1992-06-01 | 1993-12-09 | Takeshi Kawakita | Pyridine compound and pharmaceutical use thereof |
| JPH08507054A (ja) * | 1993-02-17 | 1996-07-30 | ビイク グルデン ロンベルク ヒェーミッシェ ファブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング | ヘリコバクターバクテリアに対抗するための置換されたヘテロアリールアルキルチオピリジン |
| AU680276B2 (en) * | 1993-06-29 | 1997-07-24 | Altana Pharma Ag | Substituted arylthioalkylthiopyridines |
| PL314841A1 (en) * | 1993-12-01 | 1996-09-30 | Byk Gulden Lomberg Chem Fab | Derivatives of aminoalkyl aminopyridine |
-
1995
- 1995-06-09 EE EE9600189A patent/EE03312B1/xx not_active IP Right Cessation
- 1995-06-09 WO PCT/EP1995/002237 patent/WO1995034554A1/de not_active Application Discontinuation
- 1995-06-09 RO RO96-02255A patent/RO117792B1/ro unknown
- 1995-06-09 RU RU97100641/04A patent/RU2139286C1/ru not_active IP Right Cessation
- 1995-06-09 HU HU9603339A patent/HU220062B/hu not_active IP Right Cessation
- 1995-06-09 NZ NZ288609A patent/NZ288609A/xx unknown
- 1995-06-09 CZ CZ19963624A patent/CZ288079B6/cs not_active IP Right Cessation
- 1995-06-09 US US08/750,785 patent/US5859030A/en not_active Expired - Fee Related
- 1995-06-09 PL PL95317613A patent/PL181801B1/pl unknown
- 1995-06-09 CN CN95194562A patent/CN1070488C/zh not_active Expired - Fee Related
- 1995-06-09 SK SK1576-96A patent/SK281465B6/sk unknown
- 1995-06-09 AU AU27901/95A patent/AU697572B2/en not_active Ceased
- 1995-06-09 CA CA002192202A patent/CA2192202A1/en not_active Abandoned
- 1995-06-09 EP EP95923288A patent/EP0764161A1/de not_active Withdrawn
- 1995-06-09 JP JP8501598A patent/JPH10501254A/ja not_active Withdrawn
-
1996
- 1996-11-21 BG BG101002A patent/BG63502B1/bg unknown
- 1996-12-03 NO NO19965162A patent/NO311618B1/no unknown
- 1996-12-09 FI FI964909A patent/FI964909A0/fi unknown
- 1996-12-10 MX MX9606300A patent/MX9606300A/es not_active IP Right Cessation
-
1998
- 1998-02-10 HK HK98101012A patent/HK1001957A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2192202A1 (en) | 1995-12-21 |
| RU2139286C1 (ru) | 1999-10-10 |
| CZ288079B6 (cs) | 2001-04-11 |
| HUT75516A (en) | 1997-05-28 |
| EP0764161A1 (de) | 1997-03-26 |
| AU697572B2 (en) | 1998-10-08 |
| MX9606300A (es) | 1998-06-30 |
| CZ362496A3 (en) | 1997-08-13 |
| SK157696A3 (en) | 1997-06-04 |
| HU220062B (hu) | 2001-10-28 |
| NO311618B1 (no) | 2001-12-17 |
| NO965162D0 (no) | 1996-12-03 |
| BG101002A (en) | 1997-08-29 |
| US5859030A (en) | 1999-01-12 |
| FI964909A (fi) | 1996-12-09 |
| PL317613A1 (en) | 1997-04-14 |
| JPH10501254A (ja) | 1998-02-03 |
| HK1001957A1 (en) | 1998-07-24 |
| CN1070488C (zh) | 2001-09-05 |
| FI964909A0 (fi) | 1996-12-09 |
| AU2790195A (en) | 1996-01-05 |
| EE03312B1 (et) | 2000-12-15 |
| WO1995034554A1 (de) | 1995-12-21 |
| NZ288609A (en) | 1998-12-23 |
| RO117792B1 (ro) | 2002-07-30 |
| HU9603339D0 (en) | 1997-01-28 |
| SK281465B6 (sk) | 2001-04-09 |
| PL181801B1 (pl) | 2001-09-28 |
| NO965162L (no) | 1997-02-05 |
| CN1159803A (zh) | 1997-09-17 |
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