FI964909A - Substituoidut aryylialkyylitioalkyylipyridiinit Helicobacter-bakteerien torjumiseksi - Google Patents

Substituoidut aryylialkyylitioalkyylipyridiinit Helicobacter-bakteerien torjumiseksi Download PDF

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Publication number
FI964909A
FI964909A FI964909A FI964909A FI964909A FI 964909 A FI964909 A FI 964909A FI 964909 A FI964909 A FI 964909A FI 964909 A FI964909 A FI 964909A FI 964909 A FI964909 A FI 964909A
Authority
FI
Finland
Prior art keywords
arylalkylthioalkylpyridines
substituted
control
helicobacter bacteria
helicobacter
Prior art date
Application number
FI964909A
Other languages
English (en)
Swedish (sv)
Other versions
FI964909A0 (fi
Inventor
Guido Hanauer
Wolfgang-Alexander Simon
Peter Zimmermann
Wolfgang Opferkuch
Bernhard Kohl
Gerhard Grundler
Joerg Senn-Bilfinger
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of FI964909A0 publication Critical patent/FI964909A0/fi
Publication of FI964909A publication Critical patent/FI964909A/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
FI964909A 1994-06-10 1996-12-09 Substituoidut aryylialkyylitioalkyylipyridiinit Helicobacter-bakteerien torjumiseksi FI964909A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH184594 1994-06-10
PCT/EP1995/002237 WO1995034554A1 (de) 1994-06-10 1995-06-09 Substituierte arylalkylthioalkylthiopyridine zur bekämpfung von helicobacter-bakterien

Publications (2)

Publication Number Publication Date
FI964909A0 FI964909A0 (fi) 1996-12-09
FI964909A true FI964909A (fi) 1996-12-09

Family

ID=4219963

Family Applications (1)

Application Number Title Priority Date Filing Date
FI964909A FI964909A (fi) 1994-06-10 1996-12-09 Substituoidut aryylialkyylitioalkyylipyridiinit Helicobacter-bakteerien torjumiseksi

Country Status (20)

Country Link
US (1) US5859030A (fi)
EP (1) EP0764161A1 (fi)
JP (1) JPH10501254A (fi)
CN (1) CN1070488C (fi)
AU (1) AU697572B2 (fi)
BG (1) BG63502B1 (fi)
CA (1) CA2192202A1 (fi)
CZ (1) CZ288079B6 (fi)
EE (1) EE03312B1 (fi)
FI (1) FI964909A (fi)
HK (1) HK1001957A1 (fi)
HU (1) HU220062B (fi)
MX (1) MX9606300A (fi)
NO (1) NO311618B1 (fi)
NZ (1) NZ288609A (fi)
PL (1) PL181801B1 (fi)
RO (1) RO117792B1 (fi)
RU (1) RU2139286C1 (fi)
SK (1) SK281465B6 (fi)
WO (1) WO1995034554A1 (fi)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997019593A1 (en) * 1995-11-28 1997-06-05 Wider Michael D Antimicrobial composition and methods of use therefor
US6479514B1 (en) 1998-05-23 2002-11-12 Altana Pharma Ag Quinoline-aminomethyl-pyridyl derivatives with anti-helicobacter activity
CA2362930C (en) * 1999-02-26 2010-10-05 Nitromed, Inc. Nitrosated and nitrosylated proton pump inhibitors, compositions and methods of use
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6780880B1 (en) 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
RU2292342C2 (ru) * 2002-07-19 2007-01-27 Уинстон Фармасьютикалс ЛЛС. Производные бензимидазола и их применение в качестве пролекарств ингибиторов протонного насоса
US20100317689A1 (en) * 2006-09-19 2010-12-16 Garst Michael E Prodrugs of proton pump inhibitors including the 1h-imidazo[4,5-b] pyridine moiety
RU2449805C1 (ru) 2011-01-27 2012-05-10 Общество С Ограниченной Ответственностью "Гармония" Пептидная фармацевтическая композиция, средство на ее основе для лечения гастродуоденальных заболеваний, вызываемых helicobacter pylori, и способ его использования
CN110294751B (zh) * 2018-03-21 2020-11-20 湖南化工研究院有限公司 具生物活性的咪唑[4,5-b]并吡啶类化合物及其制备方法和应用
CN110156752B (zh) * 2019-05-28 2021-03-19 沈阳药科大学 2-[(吡啶-2-基甲基)硫基]-1h-苯并咪唑类化合物及应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1234058A (fi) * 1968-10-21 1971-06-03
JPS604826B2 (ja) * 1978-09-12 1985-02-06 藤沢薬品工業株式会社 インダゾ−ル酢酸類の製造法
US4387225A (en) * 1981-01-15 1983-06-07 William H. Rorer, Inc. Heterocyclic alkylene triazinones
JPS57200386A (en) * 1981-06-04 1982-12-08 Yoshitomi Pharmaceut Ind Ltd Novel 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its salts
IL71665A (en) * 1983-05-03 1988-05-31 Byk Gulden Lomberg Chem Fab Fluoro-(2-pyridyl-methylthio)-dioxolo-(and dioxino-)benzimidazoles,processes for their preparation and pharmaceutical compositions containing the same
JP2563619B2 (ja) * 1989-11-28 1996-12-11 株式会社東芝 ダクト用換気扇
CA2136993A1 (en) * 1992-06-01 1993-12-09 Takeshi Kawakita Pyridine compound and pharmaceutical use thereof
US5504082A (en) * 1992-06-01 1996-04-02 Yoshitomi Pharmaceutical Industries, Ltd. Pyridine compound and pharmaceutical compostions
WO1994019346A1 (de) * 1993-02-17 1994-09-01 Byk Gulden Lomberg Chemische Fabrik Gmbh Substituierte heteroarylalkylthiopyridine zur bekämpfung von helicobacter bakterien
RU2154062C2 (ru) * 1993-06-29 2000-08-10 Бик Гульден Ломберг Хемише Фабрик Гмбх. Замещенные арилтиоалкилтиопиридины, способ их получения, лекарственное средство на их основе и способ получения лекарственного средства.
DK0731801T3 (da) * 1993-12-01 2002-02-18 Byk Gulden Lomberg Chem Fab Substituerede aminoaylkylaminopyridiner

Also Published As

Publication number Publication date
CN1159803A (zh) 1997-09-17
BG63502B1 (bg) 2002-03-29
CZ362496A3 (en) 1997-08-13
HU220062B (hu) 2001-10-28
AU697572B2 (en) 1998-10-08
SK157696A3 (en) 1997-06-04
NO311618B1 (no) 2001-12-17
SK281465B6 (sk) 2001-04-09
FI964909A0 (fi) 1996-12-09
HU9603339D0 (en) 1997-01-28
RO117792B1 (ro) 2002-07-30
WO1995034554A1 (de) 1995-12-21
HUT75516A (en) 1997-05-28
PL181801B1 (pl) 2001-09-28
MX9606300A (es) 1998-06-30
CA2192202A1 (en) 1995-12-21
EE03312B1 (et) 2000-12-15
CN1070488C (zh) 2001-09-05
JPH10501254A (ja) 1998-02-03
US5859030A (en) 1999-01-12
HK1001957A1 (en) 1998-07-24
PL317613A1 (en) 1997-04-14
NO965162D0 (no) 1996-12-03
NO965162L (no) 1997-02-05
AU2790195A (en) 1996-01-05
NZ288609A (en) 1998-12-23
BG101002A (en) 1997-08-29
RU2139286C1 (ru) 1999-10-10
EP0764161A1 (de) 1997-03-26
CZ288079B6 (cs) 2001-04-11

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