BG63105B1 - Стъпаловидни полимерни комплекси, метод за тяхното получаване и фармацевтични средства, който ги съдържат - Google Patents

Стъпаловидни полимерни комплекси, метод за тяхното получаване и фармацевтични средства, който ги съдържат Download PDF

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Publication number
BG63105B1
BG63105B1 BG102565A BG10256598A BG63105B1 BG 63105 B1 BG63105 B1 BG 63105B1 BG 102565 A BG102565 A BG 102565A BG 10256598 A BG10256598 A BG 10256598A BG 63105 B1 BG63105 B1 BG 63105B1
Authority
BG
Bulgaria
Prior art keywords
group
groups
coch
mmol
optionally
Prior art date
Application number
BG102565A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG102565A (en
Inventor
Heribert Schmitt-Willich
Johannes Platzek
Bernd Raduechel
Hanns-Joachim Weinmann
Wolfgang Ebert
Bernd Misselwitz
Andreas Muehler
Thomas Frenzel
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of BG102565A publication Critical patent/BG102565A/xx
Publication of BG63105B1 publication Critical patent/BG63105B1/bg

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/12—Macromolecular compounds
    • A61K49/124—Macromolecular compounds dendrimers, dendrons, hyperbranched compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
BG102565A 1995-12-22 1998-06-19 Стъпаловидни полимерни комплекси, метод за тяхното получаване и фармацевтични средства, който ги съдържат BG63105B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19549286A DE19549286A1 (de) 1995-12-22 1995-12-22 Kaskaden-Polymer-Komplexe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
PCT/EP1996/005315 WO1997023245A1 (de) 1995-12-22 1996-11-29 Kaskaden-polymer-komplexe, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel

Publications (2)

Publication Number Publication Date
BG102565A BG102565A (en) 1999-06-30
BG63105B1 true BG63105B1 (bg) 2001-04-30

Family

ID=7781739

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102565A BG63105B1 (bg) 1995-12-22 1998-06-19 Стъпаловидни полимерни комплекси, метод за тяхното получаване и фармацевтични средства, който ги съдържат

Country Status (23)

Country Link
US (1) US6057419A (pl)
EP (1) EP0868202B1 (pl)
JP (1) JP4031041B2 (pl)
KR (1) KR100461476B1 (pl)
AT (1) ATE222776T1 (pl)
BG (1) BG63105B1 (pl)
CA (1) CA2241187A1 (pl)
CZ (1) CZ294238B6 (pl)
DE (2) DE19549286A1 (pl)
DK (1) DK0868202T3 (pl)
ES (1) ES2181924T3 (pl)
IL (1) IL124677A (pl)
MX (1) MX9804860A (pl)
NO (1) NO314545B1 (pl)
NZ (1) NZ323397A (pl)
PL (1) PL187835B1 (pl)
PT (1) PT868202E (pl)
RU (1) RU2197495C2 (pl)
SK (1) SK283334B6 (pl)
TW (1) TW520377B (pl)
UA (1) UA50753C2 (pl)
WO (1) WO1997023245A1 (pl)
ZA (1) ZA9610822B (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19652387A1 (de) * 1996-12-04 1998-06-10 Schering Ag Macrocyclische Metallkomplexcarbonsäuren, ihre Verwendung sowie Verfahren zu ihrer Herstellung
DE19728954C1 (de) * 1997-06-30 1999-04-22 Schering Ag Saccharid-Konjugate, diese enthaltende pharmazeutische Mittel, Verfahren zu ihrer Herstellung und ihre Verwendung
DE19744003B4 (de) * 1997-09-26 2004-07-08 Schering Ag Kontrastmittel für das Infarkt- und Nekroseimaging
DE19758105A1 (de) * 1997-12-18 1999-06-24 Schering Ag Dendritische Polymer-Saccharid-Konjugate, diese enthaltende pharmazeutische Mittel, Verfahren zu ihrer Herstellung und ihre Verwendung
US7405320B2 (en) * 1998-06-22 2008-07-29 Immunomedics, Inc. Therapeutic and diagnostic conjugates for use with multispecific antibodies
FR2841258A1 (fr) * 2002-06-20 2003-12-26 Pf Medicament Procede et preparation de mononegavirus recombinants et leurs applications
KR20080108989A (ko) * 2006-03-14 2008-12-16 말린크로트, 인코포레이티드 테트라아자거대고리 유도체의 금속 착체
DE102007002726A1 (de) * 2007-01-18 2008-07-31 Bayer Schering Pharma Aktiengesellschaft Neue Kaskaden-Polymer-Komplexe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
US9463254B2 (en) 2013-06-07 2016-10-11 The Board Of Regents Of The University Of Texas System Molecular design toward dual-modality probes for radioisotope-based imaging (PET or SPECT) and MRI
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
WO2018096082A1 (en) 2016-11-28 2018-05-31 Bayer Pharma Aktiengesellschaft High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging
CA3120665A1 (en) 2018-11-23 2020-05-28 Bayer Aktiengesellschaft Formulation of contrast media and process of preparation thereof
RU2706705C1 (ru) * 2019-03-28 2019-11-20 Федеральное государственное бюджетное учреждение науки Иркутский институт химии им.А.Е.Фаворского Сибирского отделения Российской академии наук Водорастворимые магнитоактивные нанобиокомпозиты флавоноидных комплексов гадолиния на основе природного конъюгата арабиногалактана с биофлавоноидами и способ получения этих нанобиокомпозитов

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527524A (en) * 1986-08-18 1996-06-18 The Dow Chemical Company Dense star polymer conjugates
DE3938992A1 (de) * 1989-11-21 1991-05-23 Schering Ag Kaskadenpolymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
DE4344460A1 (de) * 1993-12-22 1995-06-29 Schering Ag Metallkomplexe von dendrimeren Makromolekülen, diese enthaltende diagnostische Mittel sowie Verfahren zur Herstellung der Komplexe und Mittel
GB9404208D0 (en) * 1994-03-04 1994-04-20 Nycomed Salutar Inc Chelants
GB9407812D0 (en) * 1994-04-20 1994-06-15 Nycomed Salutar Inc Compounds
DE4425857A1 (de) * 1994-07-07 1996-01-11 Schering Ag Kaskaden-Polymer-Komplexe, Verfahren zur ihrer Herstellung und diese enthaltende pharmazeutische Mittel
US5919433A (en) * 1996-12-04 1999-07-06 Schering Aktiengesellschaft Macrocyclic metal complex carboxylic acids, their use as well as process for their production

Also Published As

Publication number Publication date
EP0868202A1 (de) 1998-10-07
NO314545B1 (no) 2003-04-07
TW520377B (en) 2003-02-11
JP4031041B2 (ja) 2008-01-09
DE19549286A1 (de) 1997-06-26
ES2181924T3 (es) 2003-03-01
CZ294238B6 (cs) 2004-11-10
ZA9610822B (en) 1997-06-27
WO1997023245A1 (de) 1997-07-03
DK0868202T3 (da) 2002-12-09
NZ323397A (en) 1999-11-29
US6057419A (en) 2000-05-02
NO982903D0 (no) 1998-06-22
PT868202E (pt) 2003-01-31
ATE222776T1 (de) 2002-09-15
UA50753C2 (uk) 2002-11-15
CZ198198A3 (cs) 1998-09-16
IL124677A0 (en) 1998-12-06
RU2197495C2 (ru) 2003-01-27
PL327977A1 (en) 1999-01-04
KR19990076638A (ko) 1999-10-15
DE59609603D1 (de) 2002-10-02
PL187835B1 (pl) 2004-10-29
NO982903L (no) 1998-06-22
BG102565A (en) 1999-06-30
CA2241187A1 (en) 1997-07-03
IL124677A (en) 2005-03-20
SK85498A3 (en) 1998-11-04
JP2000510880A (ja) 2000-08-22
SK283334B6 (sk) 2003-06-03
MX9804860A (es) 1998-10-31
KR100461476B1 (ko) 2005-04-06
EP0868202B1 (de) 2002-08-28

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