BG60798B2 - Нови морфолинови производни,метод за тяхното получаване, фармацевтични средства,съдържащи тези производни,и използването им като антимикотици - Google Patents

Нови морфолинови производни,метод за тяхното получаване, фармацевтични средства,съдържащи тези производни,и използването им като антимикотици Download PDF

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Publication number
BG60798B2
BG60798B2 BG98580A BG9858094A BG60798B2 BG 60798 B2 BG60798 B2 BG 60798B2 BG 98580 A BG98580 A BG 98580A BG 9858094 A BG9858094 A BG 9858094A BG 60798 B2 BG60798 B2 BG 60798B2
Authority
BG
Bulgaria
Prior art keywords
formula
compound
compounds
phenyl
cis
Prior art date
Application number
BG98580A
Other languages
Bulgarian (bg)
English (en)
Inventor
Albert Pfiffner
Original Assignee
F. Hoffmann- La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH756079A external-priority patent/CH644113A5/de
Application filed by F. Hoffmann- La Roche Ag filed Critical F. Hoffmann- La Roche Ag
Publication of BG60798B2 publication Critical patent/BG60798B2/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BG98580A 1979-08-17 1994-02-25 Нови морфолинови производни,метод за тяхното получаване, фармацевтични средства,съдържащи тези производни,и използването им като антимикотици BG60798B2 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH756079A CH644113A5 (en) 1979-08-17 1979-08-17 N-substituted 2,6-dimethylmorpholine compounds
CH418780 1980-05-29

Publications (1)

Publication Number Publication Date
BG60798B2 true BG60798B2 (bg) 1996-03-29

Family

ID=25694874

Family Applications (1)

Application Number Title Priority Date Filing Date
BG98580A BG60798B2 (bg) 1979-08-17 1994-02-25 Нови морфолинови производни,метод за тяхното получаване, фармацевтични средства,съдържащи тези производни,и използването им като антимикотици

Country Status (31)

Country Link
EP (1) EP0024334B1 (fr)
AR (1) AR225318A1 (fr)
AT (1) ATE4206T1 (fr)
AU (1) AU530398B2 (fr)
BG (1) BG60798B2 (fr)
CA (1) CA1128943A (fr)
CS (1) CS402091A3 (fr)
CU (1) CU35298A (fr)
DE (3) DE3064267D1 (fr)
DK (1) DK150509C (fr)
ES (2) ES494314A0 (fr)
FI (1) FI69455C (fr)
FR (1) FR2463767B1 (fr)
GB (1) GB2056454B (fr)
HR (1) HRP930340B1 (fr)
HU (1) HU182189B (fr)
IE (1) IE52642B1 (fr)
IL (1) IL60813A (fr)
IT (1) IT1220970B (fr)
LU (1) LU82713A1 (fr)
MC (1) MC1345A1 (fr)
MY (1) MY8500272A (fr)
NL (1) NL8004537A (fr)
NO (1) NO153176C (fr)
NZ (1) NZ194628A (fr)
PH (1) PH15480A (fr)
PT (1) PT71708B (fr)
SE (1) SE447730B (fr)
SI (1) SI8011754A8 (fr)
YU (1) YU43475B (fr)
ZW (1) ZW15780A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3421810A1 (de) * 1984-06-12 1985-12-12 Basf Ag, 6700 Ludwigshafen Phenylalkylamine - bioregulatoren
CA2008775C (fr) * 1989-02-24 1998-12-22 Alberto Ferro Vernis a ongles
EP0446585A1 (fr) * 1990-03-12 1991-09-18 F. Hoffmann-La Roche Ag Procédé de lutte contre les infections fongiques en aquaculture
EP1749825A1 (fr) * 2005-07-28 2007-02-07 Galderma S.A. Procédé pour la préparation d' amorolfine
EP1749826A1 (fr) * 2005-07-28 2007-02-07 Galderma S.A. Procédé pour al préparation de bépromoline
EP1842848A1 (fr) * 2006-04-03 2007-10-10 Galderma S.A. Procédé de préparation de 3-[4-(1,1-diméthyl-propyl)-phényl]-2-méthyl-propionaldéhyde et de cis-4{3-[4-(1,1-diméthyl-propyl)-phényl] 2-méthyl-propyl}-2,6-diméthyl-morpholine (amorolfine)
EP1935889A1 (fr) * 2006-12-21 2008-06-25 Galderma S.A. Procédé de production d'amorolfine
ITFI20090032A1 (it) 2009-02-20 2010-08-21 Synteco S P A Prodotti Di Sintesi Per L Ind Processo di produzione industriale dell'amorolfina cloridrato

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT354187B (de) * 1976-11-22 1979-12-27 Hoffmann La Roche Fungizides mittel
DE2656747C2 (de) * 1976-12-15 1984-07-05 Basf Ag, 6700 Ludwigshafen Morpholinderivate
ZA792242B (en) * 1978-05-16 1980-05-28 Hoffmann La Roche Heterocyclic compounds
DE2830127A1 (de) * 1978-07-08 1980-01-17 Basf Ag N-arylpropyl-substituierte cyclische amine
DE2830999A1 (de) * 1978-07-14 1980-01-31 Basf Ag Verfahren zur herstellung von stereoisomeren n-aralkyl-2,6-dimethylmorpholinen
ATE3111T1 (de) * 1978-08-08 1983-05-15 F. Hoffmann-La Roche & Co. Aktiengesellschaft Verfahren zur herstellung von phenyl-propylmorpholin- und -piperidin-derivaten.
DE2907614A1 (de) * 1979-02-27 1980-09-04 Basf Ag Optische aktive formen des 1- eckige klammer auf 3-(p-tert.-buthylphenyl)-2- methylpropyl eckige klammer zu -cis-3,5- dimethylmorpholins

Also Published As

Publication number Publication date
EP0024334A1 (fr) 1981-03-04
IL60813A0 (en) 1980-10-26
YU43475B (en) 1989-08-31
DK355180A (da) 1981-02-18
CU35298A (en) 1982-03-28
ATE4206T1 (de) 1983-08-15
DK150509B (da) 1987-03-16
DE3064267D1 (en) 1983-08-25
CA1128943A (fr) 1982-08-03
SI8011754A8 (sl) 1997-06-30
AR225318A1 (es) 1982-03-15
ES8200355A1 (es) 1981-11-01
DE3029966A1 (de) 1981-03-26
AU530398B2 (en) 1983-07-14
FI69455B (fi) 1985-10-31
PH15480A (en) 1983-01-27
NO153176B (no) 1985-10-21
HU182189B (en) 1983-12-28
NO802453L (no) 1981-02-18
IL60813A (en) 1984-06-29
NO153176C (no) 1986-01-29
EP0024334B1 (fr) 1983-07-20
ES494314A0 (es) 1981-11-01
LU82713A1 (de) 1982-05-10
IT1220970B (it) 1990-06-21
DK150509C (da) 1987-10-12
PT71708B (en) 1982-04-06
PT71708A (en) 1980-10-01
CS402091A3 (en) 1992-05-13
NZ194628A (en) 1984-09-28
GB2056454B (en) 1983-11-09
FR2463767A1 (fr) 1981-02-27
ZW15780A1 (en) 1981-03-18
HRP930340B1 (en) 1996-12-31
NL8004537A (nl) 1981-02-19
GB2056454A (en) 1981-03-18
AU6132180A (en) 1981-02-19
SE447730B (sv) 1986-12-08
ES8201563A1 (es) 1982-01-01
FR2463767B1 (fr) 1985-07-12
FI69455C (fi) 1986-02-10
MY8500272A (en) 1985-12-31
IE801729L (en) 1981-02-17
IE52642B1 (en) 1988-01-06
IT8023283A0 (it) 1980-07-07
YU175480A (en) 1983-02-28
ES499957A0 (es) 1982-01-01
DE19375077I2 (de) 2001-04-12
SE8005784L (sv) 1981-02-18
FI802418A (fi) 1981-02-18
MC1345A1 (fr) 1981-06-22

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