BG60101A3 - Method for preparing of 4-fluoro-2-[[(4-methoxy-2-pyridinyl)methyl]thionil]-1h-benzimidazo le - Google Patents

Method for preparing of 4-fluoro-2-[[(4-methoxy-2-pyridinyl)methyl]thionil]-1h-benzimidazo le

Info

Publication number
BG60101A3
BG60101A3 BG94657A BG9465791A BG60101A3 BG 60101 A3 BG60101 A3 BG 60101A3 BG 94657 A BG94657 A BG 94657A BG 9465791 A BG9465791 A BG 9465791A BG 60101 A3 BG60101 A3 BG 60101A3
Authority
BG
Bulgaria
Prior art keywords
pyridinyl
fluoro
methoxy
methyl
thionil
Prior art date
Application number
BG94657A
Other languages
English (en)
Inventor
Arne E Braendstroem
Per L Lindberg
Gunnel E Sunden
Original Assignee
Se Ab Haessle
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE19888804629A external-priority patent/SE8804629D0/xx
Priority claimed from SE8902170A external-priority patent/SE8902170D0/xx
Application filed by Se Ab Haessle filed Critical Se Ab Haessle
Publication of BG60101A3 publication Critical patent/BG60101A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms
BG94657A 1988-12-22 1991-06-19 Method for preparing of 4-fluoro-2-[[(4-methoxy-2-pyridinyl)methyl]thionil]-1h-benzimidazo le BG60101A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE19888804629A SE8804629D0 (sv) 1988-12-22 1988-12-22 New therapeutically active compounds
SE8902170A SE8902170D0 (sv) 1989-06-16 1989-06-16 Therapeutically active compounds

Publications (1)

Publication Number Publication Date
BG60101A3 true BG60101A3 (en) 1993-10-15

Family

ID=26660387

Family Applications (1)

Application Number Title Priority Date Filing Date
BG94657A BG60101A3 (en) 1988-12-22 1991-06-19 Method for preparing of 4-fluoro-2-[[(4-methoxy-2-pyridinyl)methyl]thionil]-1h-benzimidazo le

Country Status (27)

Country Link
US (1) US5025024A (xx)
EP (1) EP0449935B1 (xx)
JP (1) JP2793905B2 (xx)
KR (1) KR910700248A (xx)
CN (1) CN1028233C (xx)
AT (1) ATE110723T1 (xx)
AU (1) AU639429B2 (xx)
BG (1) BG60101A3 (xx)
CA (1) CA2005980C (xx)
CS (1) CS276361B6 (xx)
DE (1) DE68917937T2 (xx)
DK (1) DK122191A (xx)
EG (1) EG19302A (xx)
FI (1) FI913034A0 (xx)
GR (1) GR1000316B (xx)
HU (1) HUT57204A (xx)
IE (1) IE64199B1 (xx)
IL (1) IL92799A (xx)
LV (1) LV10267B (xx)
MY (1) MY129946A (xx)
NO (1) NO178336C (xx)
NZ (1) NZ231874A (xx)
PH (1) PH27446A (xx)
PL (1) PL160767B1 (xx)
PT (1) PT92649B (xx)
WO (1) WO1990006924A1 (xx)
YU (1) YU47338B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6699885B2 (en) 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
CA2472103A1 (en) * 2002-01-25 2003-08-07 Santarus, Inc. Transmucosal delivery of proton pump inhibitors
CA2517005A1 (en) * 2003-02-20 2004-09-02 Santarus, Inc. A novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
US20050031700A1 (en) * 2003-07-18 2005-02-10 Sanatarus, Inc. Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
AR045062A1 (es) * 2003-07-18 2005-10-12 Santarus Inc Formulaciones farmaceuticas para inhibir la secrecion de acido y metodos para preparar y utilizarlas
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (xx) * 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
IL71664A (en) * 1983-05-03 1987-11-30 Byk Gulden Lomberg Chem Fab Fluoroalkoxy compounds,process for their preparation and pharmaceutical compositions containing the same
JPS6150979A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
US4738975A (en) * 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
NZ222495A (en) * 1986-11-21 1991-04-26 Haessle Ab Benzimidazole derivatives and pharmaceutical compositions
FI96860C (fi) * 1987-06-17 1996-09-10 Eisai Co Ltd Analogiamenetelmä lääkeaineena käytettävän pyridiinijohdannaisen valmistamiseksi

Also Published As

Publication number Publication date
NO178336C (no) 1996-03-06
FI913034A0 (fi) 1991-06-20
AU639429B2 (en) 1993-07-29
PT92649B (pt) 1995-09-12
PH27446A (en) 1993-07-02
CA2005980C (en) 1999-07-13
CN1028233C (zh) 1995-04-19
EG19302A (en) 1994-11-30
GR890100833A (en) 1991-03-15
NZ231874A (en) 1992-05-26
IL92799A (en) 1994-01-25
HU901095D0 (en) 1991-09-30
IL92799A0 (en) 1990-09-17
WO1990006924A1 (en) 1990-06-28
MY129946A (en) 2007-05-31
DE68917937T2 (de) 1995-01-05
US5025024A (en) 1991-06-18
ATE110723T1 (de) 1994-09-15
CA2005980A1 (en) 1990-06-22
AU4813290A (en) 1990-07-10
DE68917937D1 (de) 1994-10-06
EP0449935B1 (en) 1994-08-31
KR910700248A (ko) 1991-03-14
JP2793905B2 (ja) 1998-09-03
YU47338B (sh) 1995-01-31
NO178336B (no) 1995-11-27
PL160767B1 (pl) 1993-04-30
HUT57204A (en) 1991-11-28
PT92649A (pt) 1990-06-29
CS734389A3 (en) 1992-01-15
DK122191A (da) 1991-06-24
EP0449935A1 (en) 1991-10-09
CS276361B6 (en) 1992-05-13
YU242789A (en) 1991-04-30
JPH04502460A (ja) 1992-05-07
CN1043937A (zh) 1990-07-18
IE64199B1 (en) 1995-07-12
NO912414D0 (no) 1991-06-20
DK122191D0 (da) 1991-06-21
LV10267B (en) 1995-02-20
GR1000316B (el) 1992-06-25
NO912414L (no) 1991-08-06
IE894050L (en) 1990-06-22
LV10267A (lv) 1994-10-20

Similar Documents

Publication Publication Date Title
SE8804629A (xx)
EP0221041A3 (en) Benzimidazole derivatives, process for their preparation and their pharmaceutical use
KR890700125A (ko) 신규 벤즈이미다졸 유도체, 그 제조방법 및 이 화합물을 함유하는 제약 조성물
IL92797A0 (en) Therapeutical active substituted benzimidazole and process for its preparation
BG60101A3 (en) Method for preparing of 4-fluoro-2-[[(4-methoxy-2-pyridinyl)methyl]thionil]-1h-benzimidazo le
JO1653B1 (en) The current benzimidazole is a therapeutically active method for preparing it
JO1664B1 (en) The compound has the effect of immobilizing gastric acid and the process of preparing it
JO1679B1 (en) A new, therapeutically active compound and method for preparing it
JO1519B1 (en) New compounds (new benzimidazole derivatives are effective as ulcers)