BG47034A3 - Method for preparing of 7- /meta- substituted/- phenylglycine- 1- carba- 1- dithiacephalosporines - Google Patents

Method for preparing of 7- /meta- substituted/- phenylglycine- 1- carba- 1- dithiacephalosporines

Info

Publication number
BG47034A3
BG47034A3 BG081345A BG8134587A BG47034A3 BG 47034 A3 BG47034 A3 BG 47034A3 BG 081345 A BG081345 A BG 081345A BG 8134587 A BG8134587 A BG 8134587A BG 47034 A3 BG47034 A3 BG 47034A3
Authority
BG
Bulgaria
Prior art keywords
dithiacephalosporines
carba
phenylglycine
meta
substituted
Prior art date
Application number
BG081345A
Other languages
Bulgarian (bg)
English (en)
Inventor
Robin Grey
John Webber
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of BG47034A3 publication Critical patent/BG47034A3/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D463/00Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16Nitrogen atoms
    • C07D463/18Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG081345A 1986-10-03 1987-10-02 Method for preparing of 7- /meta- substituted/- phenylglycine- 1- carba- 1- dithiacephalosporines BG47034A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91517386A 1986-10-03 1986-10-03

Publications (1)

Publication Number Publication Date
BG47034A3 true BG47034A3 (en) 1990-04-16

Family

ID=25435354

Family Applications (1)

Application Number Title Priority Date Filing Date
BG081345A BG47034A3 (en) 1986-10-03 1987-10-02 Method for preparing of 7- /meta- substituted/- phenylglycine- 1- carba- 1- dithiacephalosporines

Country Status (17)

Country Link
EP (1) EP0266896B1 (pt)
JP (1) JPS6396186A (pt)
KR (1) KR880005125A (pt)
CN (1) CN87107149A (pt)
AT (2) ATE79119T1 (pt)
BG (1) BG47034A3 (pt)
DE (1) DE3780909T2 (pt)
DK (1) DK518487A (pt)
FI (1) FI874311A (pt)
GR (1) GR3005920T3 (pt)
HU (1) HU200179B (pt)
IE (1) IE872646L (pt)
IL (1) IL84051A0 (pt)
NZ (1) NZ222015A (pt)
PL (1) PL151703B1 (pt)
PT (1) PT85850B (pt)
ZA (1) ZA877398B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA89829B (en) * 1988-02-05 1990-10-31 Lilly Co Eli Crystalline b-lactam solvate
CA2442219C (en) 2001-03-28 2007-09-11 Schering Corporation Enantioselective synthesis of azetidinone intermediate compounds
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
US20030236243A1 (en) * 2002-05-14 2003-12-25 Shoichet Brian K. Sterically-awkward beta-lactamase inhibitors
US7235543B2 (en) 2003-03-07 2007-06-26 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP4589919B2 (ja) 2003-03-07 2010-12-01 シェーリング コーポレイション 高コレステロール血症の処置のための、置換アゼチジノン化合物、これらの処方物および使用
CN102144992B (zh) * 2011-03-10 2013-04-10 浙江大学 苯基甘氨酸衍生物制备对金黄色葡萄球菌有抑菌和杀菌活性的抗菌剂的用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697515A (en) * 1963-02-18 1972-10-10 Ciba Geigy Corp Process for splitting the 7-n-acyl group from cephalosporin compounds
NO155548C (no) * 1979-02-10 1987-04-15 Kyowa Hakko Kogyo Kk Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger.
NO155547C (no) * 1979-02-10 1987-04-15 Kyowa Hakko Kogyo Kk Optisk aktive cefalosporin-analoge og salter derav samt fremgangsmaate for deres fremstilling.
JPS5672698A (en) * 1979-11-14 1981-06-16 Kyowa Hakko Kogyo Co Ltd Preparation of optically active cephalosporin analogue
JPS60174787A (ja) * 1984-02-21 1985-09-09 Kyowa Hakko Kogyo Co Ltd 3位置換カルバセフエム化合物
US4673737A (en) * 1985-08-02 1987-06-16 Harvard University 7-acylamino-(or 7-amino)-3-trifluoromethylsulfonyloxy-1-carba(1-dethia)-3-cephem-4-carboxylic acids and esters thereof

Also Published As

Publication number Publication date
EP0266896A1 (en) 1988-05-11
PT85850A (en) 1987-11-01
FI874311A (fi) 1988-04-04
ATE79119T1 (de) 1992-08-15
DK518487A (da) 1988-04-04
ZA877398B (en) 1989-05-30
HU200179B (en) 1990-04-28
CN87107149A (zh) 1988-05-18
FI874311A0 (fi) 1987-10-01
NZ222015A (en) 1989-10-27
IL84051A0 (en) 1988-03-31
GR3005920T3 (pt) 1993-06-07
PL268034A1 (en) 1988-09-01
AU7926987A (en) 1988-04-14
DE3780909D1 (en) 1992-09-10
IE872646L (en) 1988-04-03
DE3780909T2 (de) 1993-03-04
KR880005125A (ko) 1988-06-28
PT85850B (en) 1990-01-12
HUT45053A (en) 1988-05-30
PL151703B1 (en) 1990-09-28
AT388377B (de) 1989-06-12
AU591811B2 (en) 1989-12-14
DK518487D0 (da) 1987-10-02
JPS6396186A (ja) 1988-04-27
ATA257587A (de) 1988-11-15
EP0266896B1 (en) 1992-08-05

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