BG28068A3 - Method of obtaining of 3-chlorcephalosporines - Google Patents

Method of obtaining of 3-chlorcephalosporines

Info

Publication number
BG28068A3
BG28068A3 BG036981A BG3698177A BG28068A3 BG 28068 A3 BG28068 A3 BG 28068A3 BG 036981 A BG036981 A BG 036981A BG 3698177 A BG3698177 A BG 3698177A BG 28068 A3 BG28068 A3 BG 28068A3
Authority
BG
Bulgaria
Prior art keywords
chlorcephalosporines
obtaining
chlorocephalosporins
formulated
preparing
Prior art date
Application number
BG036981A
Other languages
Bulgarian (bg)
English (en)
Inventor
Stjepan Kukolja
Douglas Spry
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of BG28068A3 publication Critical patent/BG28068A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
BG036981A 1976-08-16 1977-07-22 Method of obtaining of 3-chlorcephalosporines BG28068A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71494876A 1976-08-16 1976-08-16

Publications (1)

Publication Number Publication Date
BG28068A3 true BG28068A3 (en) 1980-02-25

Family

ID=24872131

Family Applications (1)

Application Number Title Priority Date Filing Date
BG036981A BG28068A3 (en) 1976-08-16 1977-07-22 Method of obtaining of 3-chlorcephalosporines

Country Status (20)

Country Link
US (1) US4115643A (pl)
JP (1) JPS5323994A (pl)
BE (1) BE857244A (pl)
BG (1) BG28068A3 (pl)
CA (1) CA1099256A (pl)
CH (1) CH630924A5 (pl)
CS (1) CS192588B2 (pl)
DD (1) DD131858A5 (pl)
DE (1) DE2735454A1 (pl)
ES (1) ES461587A1 (pl)
FI (1) FI66873C (pl)
FR (1) FR2362145A1 (pl)
GB (1) GB1582044A (pl)
HU (1) HU179459B (pl)
IE (1) IE45158B1 (pl)
IL (1) IL52416A (pl)
NL (1) NL7709055A (pl)
PL (1) PL110242B1 (pl)
RO (1) RO71908A (pl)
SU (1) SU1018586A3 (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
US4226986A (en) * 1979-02-01 1980-10-07 Eli Lilly And Company Process for halogenation of β-lactam compounds
US4223133A (en) * 1979-02-01 1980-09-16 Eli Lilly And Company Cephalosporin reduction process
US4271305A (en) * 1979-02-01 1981-06-02 Eli Lilly And Company Thiazolinoazetidinones and process therefor
US4237279A (en) * 1979-07-27 1980-12-02 Eli Lilly And Company Crystalline 3-hydroxycephalosporin solvates
US4281117A (en) * 1980-09-04 1981-07-28 Eli Lilly And Company Process for 3-chloro cephalosporin nucleus
US5159071A (en) * 1990-09-06 1992-10-27 Ranbaxy Laboratories Limited Process for the manufacture of 7-amino-3-exomethylene-3-cepham-4-carboxylic acid ester
US5350845A (en) * 1992-04-08 1994-09-27 Eli Lilly And Company Process for preparing 7-substituted-amino-3-hydroxy-3-cephem-4-protected carboxy-sulfoxide esters
IN181695B (pl) * 1992-08-10 1998-09-05 Ranbaxy Lab Ltd
US5604222A (en) * 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) * 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters
KR100390551B1 (ko) * 1996-08-22 2003-11-17 주식회사 코오롱 3-할로메틸-3-세펨-4-카르복실레이트 1-옥사이드의 제조방법
CN101190921B (zh) * 2007-11-27 2010-05-19 吉林省石油化工设计研究院 一种对硝基苄基-7-苯氧基乙酰胺-3-外亚甲基头孢-4-羧酸酯-1-β-氧化物制备方法
CN102443014B (zh) * 2011-12-29 2014-07-09 上海右手医药科技开发有限公司 3-氯头孢菌素衍生物及其合成方法与在头孢克洛制备中的应用
CN103588790A (zh) * 2013-11-29 2014-02-19 中国科学院长春应用化学研究所 7-氨基-3-氯-3-头孢-4-羧酸-对硝基苄基酯的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641014A (en) * 1968-10-03 1972-02-08 Lilly Co Eli Reduction of delta**3-cephalosporin sulfoxides
AR208068A1 (es) * 1973-02-23 1976-11-30 Lilly Co Eli Un procedimiento para preparar derivados de acidos 7-acilamido-3-halo-cefem-4-carboxilico los esteres y las sales farmaceuticamente aceptables de los mismos
US3925372A (en) * 1973-02-23 1975-12-09 Lilly Co Eli Alpha-aminoacyl-3-halo cephalosporins
US3962227A (en) * 1973-02-23 1976-06-08 Eli Lilly And Company 3-halo cephalosporins
YU36970B (en) * 1973-02-23 1984-08-31 Lilly Co Eli Process for obtaining 7-(amino)-acylamido-3-halocephalosporins

Also Published As

Publication number Publication date
FR2362145B1 (pl) 1980-02-15
ES461587A1 (es) 1978-06-01
PL110242B1 (en) 1980-07-31
JPS6120556B2 (pl) 1986-05-22
GB1582044A (en) 1980-12-31
IL52416A (en) 1980-02-29
SU1018586A3 (ru) 1983-05-15
PL200289A1 (pl) 1978-05-08
CH630924A5 (de) 1982-07-15
CS192588B2 (en) 1979-08-31
DE2735454A1 (de) 1978-02-23
FI66873B (fi) 1984-08-31
RO71908A (ro) 1981-11-24
DD131858A5 (de) 1978-07-26
FI66873C (fi) 1984-12-10
DE2735454C2 (pl) 1992-12-10
BE857244A (fr) 1978-01-30
IL52416A0 (en) 1977-08-31
CA1099256A (en) 1981-04-14
FI772339A (fi) 1978-02-17
US4115643A (en) 1978-09-19
IE45158L (en) 1978-02-16
NL7709055A (nl) 1978-02-20
JPS5323994A (en) 1978-03-06
HU179459B (en) 1982-10-28
IE45158B1 (en) 1982-06-30
FR2362145A1 (fr) 1978-03-17

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