BG28054A3 - Method of obtaining of 2-(4-aroylpiperazine-1-il)-4- amino-6,7-dimetoxyhinazoline - Google Patents

Method of obtaining of 2-(4-aroylpiperazine-1-il)-4- amino-6,7-dimetoxyhinazoline

Info

Publication number
BG28054A3
BG28054A3 BG037373A BG3737377A BG28054A3 BG 28054 A3 BG28054 A3 BG 28054A3 BG 037373 A BG037373 A BG 037373A BG 3737377 A BG3737377 A BG 3737377A BG 28054 A3 BG28054 A3 BG 28054A3
Authority
BG
Bulgaria
Prior art keywords
amino
dimetoxyhinazoline
aroylpiperazine
obtaining
dimethoxyquinazolines
Prior art date
Application number
BG037373A
Other languages
Bulgarian (bg)
English (en)
Inventor
Philip Hammen
Original Assignee
Pfizer Inc., a corporation organized аnd existing under the laws of the State of Delaware
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc., a corporation organized аnd existing under the laws of the State of Delaware filed Critical Pfizer Inc., a corporation organized аnd existing under the laws of the State of Delaware
Publication of BG28054A3 publication Critical patent/BG28054A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG037373A 1976-09-20 1977-09-20 Method of obtaining of 2-(4-aroylpiperazine-1-il)-4- amino-6,7-dimetoxyhinazoline BG28054A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/724,707 US4062844A (en) 1976-09-20 1976-09-20 Process for preparing hypotensive 2-(4-aroylpiperazin-1-yl)-amino-6,7-dimethoxyquinazolines

Publications (1)

Publication Number Publication Date
BG28054A3 true BG28054A3 (en) 1980-02-25

Family

ID=24911552

Family Applications (1)

Application Number Title Priority Date Filing Date
BG037373A BG28054A3 (en) 1976-09-20 1977-09-20 Method of obtaining of 2-(4-aroylpiperazine-1-il)-4- amino-6,7-dimetoxyhinazoline

Country Status (32)

Country Link
US (1) US4062844A (fi)
JP (1) JPS5337676A (fi)
AR (1) AR213659A1 (fi)
AT (1) AT357542B (fi)
AU (1) AU500908B2 (fi)
BE (1) BE858844A (fi)
BG (1) BG28054A3 (fi)
CA (1) CA1068699A (fi)
CH (1) CH632507A5 (fi)
CS (1) CS203172B2 (fi)
DD (1) DD132661A5 (fi)
DE (1) DE2740331C3 (fi)
DK (1) DK143340C (fi)
ES (1) ES462146A1 (fi)
FI (1) FI66610C (fi)
FR (1) FR2364918A1 (fi)
GB (1) GB1543668A (fi)
GR (1) GR69792B (fi)
HK (1) HK31181A (fi)
HU (1) HU180041B (fi)
IE (1) IE45966B1 (fi)
LU (1) LU78149A1 (fi)
MY (1) MY8100266A (fi)
NL (1) NL189132C (fi)
NO (1) NO147423C (fi)
PL (1) PL105830B1 (fi)
PT (1) PT67006B (fi)
RO (1) RO73051A (fi)
SE (1) SE435381B (fi)
SU (1) SU847919A3 (fi)
YU (1) YU39155B (fi)
ZA (1) ZA775098B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0022481A1 (en) * 1979-06-21 1981-01-21 Mitsubishi Yuka Pharmaceutical Co., Ltd. 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions
US4607034A (en) * 1979-10-29 1986-08-19 Mitsubishi Yuka Pharmaceutical Co., Ltd. Quinazoline derivatives and pharmaceutical composition thereof
JPS5793977A (en) * 1980-11-26 1982-06-11 Sankyo Co Ltd Acylaminoquinazoline derivative and its preparation
FI70411C (fi) * 1980-12-29 1986-09-19 Pfizer Foerfarande foer framstaellning av nya antihypertensiva 4-amino-6,7-dimetoxi-2-piperazinokinazolin derivat
US4625012A (en) * 1985-08-26 1986-11-25 Essex Specialty Products, Inc. Moisture curable polyurethane polymers
IT1270993B (it) * 1994-03-18 1997-05-26 Recordati Chem Pharm Derivati chinzolilamminici attivi come alfa-antagonisti
GB9708917D0 (en) * 1997-05-01 1997-06-25 Pfizer Ltd Compounds useful in therapy
US6313294B1 (en) 1998-02-04 2001-11-06 Development Center For Biotechnology Process for preparing amides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3935213A (en) * 1973-12-05 1976-01-27 Pfizer Inc. Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives

Also Published As

Publication number Publication date
RO73051A (ro) 1981-09-24
DK143340C (da) 1981-12-14
CS203172B2 (en) 1981-02-27
AR213659A1 (es) 1979-02-28
IE45966B1 (en) 1983-01-12
DK143340B (da) 1981-08-10
PL105830B1 (pl) 1979-11-30
DK395877A (da) 1978-03-21
AU2822177A (en) 1979-03-01
SE435381B (sv) 1984-09-24
JPS5337676A (en) 1978-04-06
MY8100266A (en) 1981-12-31
HK31181A (en) 1981-07-10
CA1068699A (en) 1979-12-25
FI66610C (fi) 1984-11-12
DE2740331B2 (de) 1980-06-19
AT357542B (de) 1980-07-10
PT67006A (en) 1977-10-01
CH632507A5 (de) 1982-10-15
ES462146A1 (es) 1978-06-16
NO147423C (no) 1983-04-06
YU39155B (en) 1984-06-30
AU500908B2 (en) 1979-06-07
FI66610B (fi) 1984-07-31
NL189132C (nl) 1993-01-18
US4062844A (en) 1977-12-13
PL200710A1 (pl) 1978-05-22
NO147423B (no) 1982-12-27
DE2740331A1 (de) 1978-03-23
SE7708942L (sv) 1978-03-21
NL7709736A (nl) 1978-03-22
DD132661A5 (de) 1978-10-18
HU180041B (en) 1983-01-28
YU209677A (en) 1982-06-30
IE45966L (en) 1978-03-20
FR2364918A1 (fr) 1978-04-14
ZA775098B (en) 1978-07-26
SU847919A3 (ru) 1981-07-15
GB1543668A (en) 1979-04-04
FI772629A (fi) 1978-03-21
LU78149A1 (fr) 1979-05-25
NL189132B (nl) 1992-08-17
DE2740331C3 (de) 1981-03-12
FR2364918B1 (fi) 1981-11-20
BE858844A (fr) 1978-03-20
NO773073L (no) 1978-03-21
ATA636877A (de) 1979-12-15
GR69792B (fi) 1982-07-07
PT67006B (en) 1979-02-12

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