BG107841A - Имидазолни и бензимидазолни инхибитори на каспази и използването им - Google Patents

Имидазолни и бензимидазолни инхибитори на каспази и използването им Download PDF

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Publication number
BG107841A
BG107841A BG107841A BG10784103A BG107841A BG 107841 A BG107841 A BG 107841A BG 107841 A BG107841 A BG 107841A BG 10784103 A BG10784103 A BG 10784103A BG 107841 A BG107841 A BG 107841A
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BG
Bulgaria
Prior art keywords
disease
hydrogen
amino
ring
fluoro
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BG107841A
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Bulgarian (bg)
English (en)
Inventor
David Kay
Julian Golec
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Vertex Pharmaceuticals Incorporated
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Application filed by Vertex Pharmaceuticals Incorporated filed Critical Vertex Pharmaceuticals Incorporated
Publication of BG107841A publication Critical patent/BG107841A/bg

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    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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BG107841A 2000-11-21 2003-05-22 Имидазолни и бензимидазолни инхибитори на каспази и използването им BG107841A (bg)

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EP (1) EP1341767B1 (zh)
JP (2) JP4349802B2 (zh)
KR (1) KR20040020042A (zh)
CN (1) CN1298707C (zh)
AP (1) AP2003002811A0 (zh)
AT (1) ATE359274T1 (zh)
AU (1) AU2002232541A1 (zh)
BG (1) BG107841A (zh)
BR (1) BR0115546A (zh)
CA (1) CA2429630A1 (zh)
CO (1) CO7250442A2 (zh)
CZ (1) CZ20031730A3 (zh)
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EA (1) EA200300601A1 (zh)
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PL (1) PL362612A1 (zh)
SK (1) SK7792003A3 (zh)
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ZA (1) ZA200303895B (zh)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20011350A1 (es) 2000-05-19 2002-01-15 Vertex Pharma PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE)
AU2003211052A1 (en) * 2002-02-11 2003-09-04 Vertex Pharmaceuticals Incorporated Phospholipids as caspase inhibitor prodrugs
AU2003225088A1 (en) 2002-04-19 2003-11-03 Vertex Pharmaceuticals Incorporated Regulation of tnf-alpha
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