BG107744A - Използване на антипрогестини за предизвикване на апоптоза в клетка - Google Patents

Използване на антипрогестини за предизвикване на апоптоза в клетка Download PDF

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Publication number
BG107744A
BG107744A BG107744A BG10774403A BG107744A BG 107744 A BG107744 A BG 107744A BG 107744 A BG107744 A BG 107744A BG 10774403 A BG10774403 A BG 10774403A BG 107744 A BG107744 A BG 107744A
Authority
BG
Bulgaria
Prior art keywords
antiprogestin
cell
tumor
breast cancer
apoptosis
Prior art date
Application number
BG107744A
Other languages
Bulgarian (bg)
English (en)
Inventor
Jens Hoffmann
Rosemarie Lichtner
Gerhard Siemeister
Martin Schneider
Ulrike Fuhrmann
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of BG107744A publication Critical patent/BG107744A/bg

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BG107744A 2000-10-18 2003-04-18 Използване на антипрогестини за предизвикване на апоптоза в клетка BG107744A (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24099100P 2000-10-18 2000-10-18
EP00250342 2000-10-18
PCT/EP2001/012006 WO2002032432A1 (en) 2000-10-18 2001-10-17 Use of antiprogestins for the induction of apoptosis in a cell

Publications (1)

Publication Number Publication Date
BG107744A true BG107744A (bg) 2004-02-27

Family

ID=26072952

Family Applications (1)

Application Number Title Priority Date Filing Date
BG107744A BG107744A (bg) 2000-10-18 2003-04-18 Използване на антипрогестини за предизвикване на апоптоза в клетка

Country Status (29)

Country Link
EP (1) EP1326617B9 (de)
JP (1) JP2004511523A (de)
KR (1) KR100668024B1 (de)
CN (1) CN1209111C (de)
AT (1) ATE334683T1 (de)
AU (2) AU2361902A (de)
BG (1) BG107744A (de)
BR (1) BR0114696A (de)
CA (1) CA2423020C (de)
CY (1) CY1105745T1 (de)
CZ (1) CZ299823B6 (de)
DE (1) DE60121980T2 (de)
DK (1) DK1326617T3 (de)
EA (1) EA010593B1 (de)
EE (1) EE200300157A (de)
ES (1) ES2269492T3 (de)
HK (1) HK1062273A1 (de)
HR (1) HRP20030388A2 (de)
HU (1) HUP0301433A3 (de)
IL (2) IL154976A0 (de)
MX (1) MXPA03002955A (de)
NO (1) NO20031741L (de)
NZ (1) NZ538347A (de)
PL (1) PL360157A1 (de)
PT (1) PT1326617E (de)
SI (1) SI1326617T1 (de)
SK (1) SK4702003A3 (de)
UA (1) UA76729C2 (de)
WO (1) WO2002032432A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY27301A1 (es) * 2001-05-25 2003-02-28 Schering Ag Uso y composiciones de antiprogestinas para el tratamiento de enfermedades de la próstata
US20040242551A1 (en) * 2003-05-28 2004-12-02 Schering Ag Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases
EP2148682A1 (de) * 2007-04-23 2010-02-03 Bayer Schering Pharma Aktiengesellschaft Kombination aus einem progesteron-rezeptorantagonisten und einem lutein-hormone-releasing hormon-agonisten und -antagonisten gegen brca-vermittelte erkrankunegn
US20080268041A1 (en) * 2007-04-23 2008-10-30 Jens Hoffmann Combination of progesterone-receptor antagonist together with none-steroidal antiestrogen for use in brca mediated diseases
JP2010524997A (ja) * 2007-04-23 2010-07-22 バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト Brca単独での、又は抗エストロゲン薬を伴った組み合わせ物としての使用のためのプロゲステロン受容体拮抗薬
GB0718167D0 (en) 2007-09-18 2007-10-31 Cancer Rec Tech Ltd Cancer marker and therapeutic target
KR102009007B1 (ko) * 2011-10-04 2019-08-08 인비비스 파마슈티컬스 인코포레이티드 항-프로게스틴 민감성 종양을 확인하고 치료하기 위한 방법 및 시스템

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19706061A1 (de) * 1997-02-07 1998-08-13 Schering Ag Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette

Also Published As

Publication number Publication date
UA76729C2 (uk) 2006-09-15
CZ299823B6 (cs) 2008-12-03
CN1469749A (zh) 2004-01-21
IL154976A (en) 2007-05-15
WO2002032432A1 (en) 2002-04-25
JP2004511523A (ja) 2004-04-15
KR100668024B1 (ko) 2007-01-15
EP1326617B1 (de) 2006-08-02
EA010593B1 (ru) 2008-10-30
SK4702003A3 (en) 2004-01-08
HK1062273A1 (en) 2004-10-29
CA2423020A1 (en) 2002-04-25
NO20031741L (no) 2003-06-17
CA2423020C (en) 2009-01-20
AU2361902A (en) 2002-04-29
DE60121980D1 (de) 2006-09-14
IL154976A0 (en) 2003-10-31
NO20031741D0 (no) 2003-04-15
MXPA03002955A (es) 2003-08-07
AU2002223619B2 (en) 2006-08-24
NZ538347A (en) 2007-03-30
EP1326617A1 (de) 2003-07-16
EE200300157A (et) 2003-08-15
HRP20030388A2 (en) 2005-04-30
BR0114696A (pt) 2003-11-18
HUP0301433A2 (hu) 2003-10-28
CY1105745T1 (el) 2010-12-22
PT1326617E (pt) 2006-12-29
EP1326617B9 (de) 2006-10-25
EA200300479A1 (ru) 2003-10-30
ES2269492T3 (es) 2007-04-01
SI1326617T1 (sl) 2007-02-28
DE60121980T2 (de) 2007-03-01
DK1326617T3 (da) 2006-12-18
KR20030057540A (ko) 2003-07-04
PL360157A1 (en) 2004-09-06
ATE334683T1 (de) 2006-08-15
CN1209111C (zh) 2005-07-06
HUP0301433A3 (en) 2010-01-28

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