BG107478A - Метод за кристализация на лозартан калий - Google Patents

Метод за кристализация на лозартан калий Download PDF

Info

Publication number
BG107478A
BG107478A BG107478A BG10747803A BG107478A BG 107478 A BG107478 A BG 107478A BG 107478 A BG107478 A BG 107478A BG 10747803 A BG10747803 A BG 10747803A BG 107478 A BG107478 A BG 107478A
Authority
BG
Bulgaria
Prior art keywords
losartan
potassium
acetone
methanol
formula
Prior art date
Application number
BG107478A
Other languages
Bulgarian (bg)
English (en)
Inventor
Rama Shankar
Venapu Reddy Ravinder
Shivakumaran Meenakshisunderam
Vijay K. Handa
Original Assignee
Aurobindo Pharma Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aurobindo Pharma Limited filed Critical Aurobindo Pharma Limited
Publication of BG107478A publication Critical patent/BG107478A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG107478A 2001-05-18 2003-01-17 Метод за кристализация на лозартан калий BG107478A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN403CH2001 2001-05-18
PCT/IN2001/000205 WO2002094816A1 (en) 2001-05-18 2001-11-20 Process for the crystallization of losartan potassium

Publications (1)

Publication Number Publication Date
BG107478A true BG107478A (bg) 2004-01-30

Family

ID=11097003

Family Applications (1)

Application Number Title Priority Date Filing Date
BG107478A BG107478A (bg) 2001-05-18 2003-01-17 Метод за кристализация на лозартан калий

Country Status (6)

Country Link
EP (1) EP1294712A1 (sk)
JP (1) JP2004520446A (sk)
BG (1) BG107478A (sk)
SI (1) SI21236A (sk)
SK (1) SK722003A3 (sk)
WO (1) WO2002094816A1 (sk)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030135041A1 (en) 2002-01-04 2003-07-17 Orchid Chemicals & Pharmaceuticals Limited, India Synthesis of ceftiofur intermediate
WO2004039352A2 (en) * 2002-10-31 2004-05-13 Ranbaxy Laboratories Limited Amorphous form of losartan potassium
ITMI20030328A1 (it) * 2003-02-25 2004-08-26 Dinamite Dipharma S P A In Forma A Bbreviata Diph Polimorfi di losartan potassio e procedimento per la loro preparazione.
WO2004076442A1 (en) * 2003-02-28 2004-09-10 Ranbaxy Laboratories Limited Polymorphs of losartan
AU2003269470A1 (en) * 2003-04-03 2004-10-25 Ipca Laboratories Limited A process for the synthesis of losartan potassium
US7345071B2 (en) 2003-05-07 2008-03-18 Ipca Laboratories Limited Process for the synthesis of Losartan potassium
RS20060125A (en) * 2003-08-27 2008-06-05 Zentiva A.S., A method of removing the triphenylmethane protecting group
ITMI20032472A1 (it) * 2003-12-16 2005-06-17 Dinamite Dipharma S P A In Forma A Bbreviata Diph Procedimento per la preparazione di losartan potassio cristallino
EP1709034A2 (en) * 2004-01-06 2006-10-11 IPCA Laboratories Limited An improved process for the synthesis of losartan potassium
CA2555294A1 (en) 2004-02-11 2005-08-25 Marina Yu Etinger Candesartan cilexetil polymorphs
WO2005084670A1 (en) * 2004-03-01 2005-09-15 Lek Pharmaceuticals D.D. Pharmaceutical formulation
KR20090029310A (ko) * 2004-05-05 2009-03-20 테바 파마슈티컬 인더스트리즈 리미티드 순도가 높은 칸데사르탄 실렉세틸의 제조
WO2010046804A2 (en) * 2008-10-21 2010-04-29 Alembic Limited A process for preparation of losartan potassium form i

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5138069A (en) * 1986-07-11 1992-08-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
DE69233734D1 (de) * 1991-11-18 2008-06-26 Du Pont 2-(2'-Triphenylmethyl-2'H-tetrazol-5'-yl)phenylborsäure als Zwischenprodukt zur Synthese von A II Receptorenantagonisten
DK0937068T3 (da) * 1996-10-29 2002-05-21 Merck & Co Inc Fremgangsmåde til krystallisation af losartan
HU222773B1 (hu) * 2000-04-21 2003-10-28 Richter Gedeon Vegyészeti Gyár Rt. Eljárás egy ismert tetrazolszármazék előállítására

Also Published As

Publication number Publication date
SI21236A (sl) 2003-12-31
WO2002094816A1 (en) 2002-11-28
SK722003A3 (en) 2003-12-02
JP2004520446A (ja) 2004-07-08
EP1294712A1 (en) 2003-03-26

Similar Documents

Publication Publication Date Title
BG107478A (bg) Метод за кристализация на лозартан калий
EP1658281B1 (en) A method of removing the triphenylmethane protecting group
US6710183B2 (en) Process for the synthesis of a known tetrazol derivative
JP2004520446A5 (sk)
EP1853591B1 (en) Method for obtaining a pharmaceutically active compound (irbesartan) and its synthesis intermediate
EP2872499A1 (en) Process for the preparation of intermediates for the synthesis of dabigatran etexilate, and crystalline forms of said intermediates
EA007323B1 (ru) Способ получения n-(1-оксопентил)-n-[[2'-(1h-тетразол-5-ил)[1,1'-дифенил] -4-ил] метил]-l-валина (валсартана)
US6350880B1 (en) Crystalline or crystallized acid addition salt of losartan and purification method of losartan
EP1912956B1 (en) Metal salts of 2'-(1h-tetraz0l-5-yl) -1,1'-biphenyl-4-carboxaldehyde
EP2016073B1 (en) Process for the preparation of pure irbesartan
WO2010029457A2 (en) An improved process for preparing losartan potassium
KR100809159B1 (ko) 로사탄의 개선된 제조방법
US7345071B2 (en) Process for the synthesis of Losartan potassium
US6916935B2 (en) Losartan potassium synthesis
EP2022790A1 (en) A process for the preparation or purification of olmesartan medoxomil
CN117858866A (zh) 用于制备色胺衍生物的方法
WO2005066158A2 (en) An improved process for the synthesis of losartan potassium
CZ20032319A3 (cs) Způsob odstraňování trifenylmethanové chránící skupiny z 1-trityl-5-(4'-subst. aminomethyl-1,1' -bifenyl-2-yl)-1H-tetrazolů a způsob výroby draselné soli losartanu, irbesartanu a valsartanu s jeho použitím
JP2004352715A (ja) Ｎ−メチル−ｎ−フェニルアミノアクロレインの合成
EP1608641A1 (en) A process for the synthesis of losartan potassium
JP2001002657A (ja) ２−アルキル−４−クロロ−５−ヒドロキシメチルイミダゾール誘導体の製造法