BG106831A - Compound and method for the treatment of pain - Google Patents

Compound and method for the treatment of pain

Info

Publication number
BG106831A
BG106831A BG106831A BG10683102A BG106831A BG 106831 A BG106831 A BG 106831A BG 106831 A BG106831 A BG 106831A BG 10683102 A BG10683102 A BG 10683102A BG 106831 A BG106831 A BG 106831A
Authority
BG
Bulgaria
Prior art keywords
compound
pain
treatment
chloro
tetrahydropyridazino
Prior art date
Application number
BG106831A
Other languages
Bulgarian (bg)
English (en)
Inventor
Thomas Bare
Dean Brown
Megan Murphy
Rebecca Urbanek
Wenhua Xiao
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BG106831A publication Critical patent/BG106831A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/503—Pyridazines; Hydrogenated pyridazines spiro-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541—Non-condensed thiazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG106831A 1999-12-23 2002-06-18 Compound and method for the treatment of pain BG106831A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17190699P 1999-12-23 1999-12-23
US23678300P 2000-09-29 2000-09-29
PCT/SE2000/002611 WO2001047927A1 (en) 1999-12-23 2000-12-19 Compound and method for the treatment of pain

Publications (1)

Publication Number Publication Date
BG106831A true BG106831A (en) 2003-03-31

Family

ID=26867555

Family Applications (1)

Application Number Title Priority Date Filing Date
BG106831A BG106831A (en) 1999-12-23 2002-06-18 Compound and method for the treatment of pain

Country Status (29)

Country Link
EP (1) EP1244662B1 (no)
JP (1) JP2003519149A (no)
KR (1) KR20020062369A (no)
CN (1) CN1188413C (no)
AR (1) AR027037A1 (no)
AT (1) ATE294177T1 (no)
AU (1) AU779703B2 (no)
BG (1) BG106831A (no)
BR (1) BR0016654A (no)
CA (1) CA2394888A1 (no)
CO (1) CO5271689A1 (no)
CZ (1) CZ296877B6 (no)
DE (1) DE60019807T2 (no)
DK (1) DK1244662T3 (no)
EE (1) EE200200350A (no)
ES (1) ES2239632T3 (no)
HK (1) HK1048811B (no)
HU (1) HUP0300313A3 (no)
IL (1) IL150208A0 (no)
IS (1) IS6427A (no)
MX (1) MXPA02006155A (no)
MY (1) MY133596A (no)
NO (1) NO20022984L (no)
NZ (1) NZ519390A (no)
PL (1) PL356664A1 (no)
PT (1) PT1244662E (no)
RU (1) RU2234507C2 (no)
SK (1) SK8792002A3 (no)
WO (1) WO2001047927A1 (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0403172D0 (sv) * 2004-12-23 2004-12-23 Astrazeneca Ab Manufacturing process
SG161256A1 (en) * 2005-04-08 2010-05-27 Abbott Lab Oral pharmaceutical formulations comprising fenofibric acid and/or its salts
JP5790533B2 (ja) * 2012-02-14 2015-10-07 住友化学株式会社 フェニルヒドラジン−β−カルボキシレート化合物の精製方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL111266A (en) * 1993-10-22 2002-03-10 Zeneca Ltd 2-HETEROARYL OR 2-ARYLPYRIDAZINO [4,5-b] QUINOLINE - 1, 10 - DIONES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
MY133596A (en) 2007-11-30
DK1244662T3 (da) 2005-07-11
JP2003519149A (ja) 2003-06-17
CZ20022177A3 (cs) 2002-11-13
ES2239632T3 (es) 2005-10-01
IL150208A0 (en) 2002-12-01
DE60019807T2 (de) 2006-01-19
HK1048811A1 (en) 2003-04-17
CN1411459A (zh) 2003-04-16
KR20020062369A (ko) 2002-07-25
PL356664A1 (en) 2004-06-28
CN1188413C (zh) 2005-02-09
HK1048811B (zh) 2005-09-30
NO20022984L (no) 2002-08-20
AU779703B2 (en) 2005-02-10
RU2234507C2 (ru) 2004-08-20
EP1244662B1 (en) 2005-04-27
WO2001047927A1 (en) 2001-07-05
CZ296877B6 (cs) 2006-07-12
CO5271689A1 (es) 2003-04-30
SK8792002A3 (en) 2003-05-02
DE60019807D1 (de) 2005-06-02
AR027037A1 (es) 2003-03-12
BR0016654A (pt) 2002-09-03
IS6427A (is) 2002-06-19
MXPA02006155A (es) 2002-12-05
EE200200350A (et) 2003-10-15
HUP0300313A2 (hu) 2003-06-28
AU2420301A (en) 2001-07-09
NO20022984D0 (no) 2002-06-20
CA2394888A1 (en) 2001-07-05
NZ519390A (en) 2003-07-25
ATE294177T1 (de) 2005-05-15
PT1244662E (pt) 2005-07-29
HUP0300313A3 (en) 2007-05-02
EP1244662A1 (en) 2002-10-02

Similar Documents

Publication Publication Date Title
WO2001027109A3 (de) Tert.-butyl-(7-methyl-imidazo[1,2-a]pyridin-3-yl)-amin-derivate
NZ514574A (en) Novel method of treatment
WO2001080843A3 (en) Inhibition of abnormal cell proliferation with camptothecin and combinations including the same
WO2002056912A3 (en) Pharmaceutical combination for the treatment of cancer containing a 4-quinazolineamine and another anti-neoplastic agent
BG103945A (en) Derivatives of 4"-substituted-9-deoxo-9a-aza-9a-homoerythromycin a
AU6257798A (en) Treatment of arrhythmias via inhibition of a multifunctional calcium/calmodulin-dependent protein kinase
MY128362A (en) Spontaneously dispersible n-benzoyl staurosporine compositions
WO2001068125A3 (en) Methods and compositions for the treatment and prevention of erectile dysfunction
WO1999022722A3 (en) Use of macrolides for the treatment of cancer and macular degeneration
WO2001028542A3 (en) Combination therapy including camptothecin
WO1999033450A3 (en) Pharmaceutical composition containing sibutramine and orlistat
NZ514558A (en) Viral treatment
AU631814B2 (en) Use of bicyclic imidazole compounds for the treatment of hyperaldosteronism
BR0007452A (pt) Uso de melagatrano ou de um derivado farmaceuticamente aceitável ou pró-droga do mesmo, método de tratamento de inflamação, e, formulação farmacêutica para uso no tratamento de inflamação
GB9907571D0 (en) Compounds
HU9802897D0 (en) Optically active pyridyl-4h-1,2,4-oxadiazine derivatives, the use thereof in the treatment of vascular diseases and pharmaceutical composition containing the compound as active ingredient
BG106831A (en) Compound and method for the treatment of pain
AU1656997A (en) Use of alpha1-adrenoreceptor antagonists in the prevention and treatment of cancer
BG106180A (en) Pharmaceutical composition containing sibutramine and orlistat
UA66932C2 (en) Complex of eletriptan and sulphobutylether-beta-cyclodextrin, pharmaceutical composition, method for their manufacture and method for treating migraine
MY133682A (en) Substituted pyrroles
WO2002076930A3 (en) Substituted diarylureas as stimulators for fas-mediated apoptosis
AU2001292499A1 (en) 7-chloro-4-hydroxy-2-(2-pyridylethyl)-1,2,5,10- tetrahydropyridazino(4,5-b)quinoline-1,10-dione and the use thereof for the treatment of pain
WO2001000187A3 (en) Pharmaceutical composition containing sibutramine and a lipase inhibitor
WO1996000068A3 (en) Combination therapy for hiv infection