BG106229A - Заместени пуринови производни като инхибитори на клетъчна адхезия - Google Patents
Заместени пуринови производни като инхибитори на клетъчна адхезия Download PDFInfo
- Publication number
- BG106229A BG106229A BG106229A BG10622901A BG106229A BG 106229 A BG106229 A BG 106229A BG 106229 A BG106229 A BG 106229A BG 10622901 A BG10622901 A BG 10622901A BG 106229 A BG106229 A BG 106229A
- Authority
- BG
- Bulgaria
- Prior art keywords
- alkyl
- aryl
- alkoxy
- group
- cycloalkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99112637A EP1065208A1 (de) | 1999-07-02 | 1999-07-02 | Substituierte Purin Derivate als Inhibitoren der Zell-Adhäsion |
PCT/EP2000/005921 WO2001002399A1 (en) | 1999-07-02 | 2000-06-26 | Substituted purine derivatives as inhibitors of cell adhesion |
Publications (1)
Publication Number | Publication Date |
---|---|
BG106229A true BG106229A (bg) | 2002-08-30 |
Family
ID=8238483
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG106229A BG106229A (bg) | 1999-07-02 | 2001-12-17 | Заместени пуринови производни като инхибитори на клетъчна адхезия |
Country Status (30)
Country | Link |
---|---|
US (1) | US6747016B1 (de) |
EP (2) | EP1065208A1 (de) |
JP (1) | JP2003503497A (de) |
KR (1) | KR20020015997A (de) |
CN (1) | CN1171888C (de) |
AR (1) | AR034242A1 (de) |
AT (1) | ATE262528T1 (de) |
AU (1) | AU774382B2 (de) |
BG (1) | BG106229A (de) |
BR (1) | BR0012050A (de) |
CA (1) | CA2376673A1 (de) |
CZ (1) | CZ20014553A3 (de) |
DE (1) | DE60009296T2 (de) |
EA (1) | EA005372B1 (de) |
EE (1) | EE200100713A (de) |
ES (1) | ES2219353T3 (de) |
HU (1) | HUP0300183A3 (de) |
IL (1) | IL147245A0 (de) |
MX (1) | MXPA01013241A (de) |
MY (1) | MY122631A (de) |
NO (1) | NO20016403L (de) |
NZ (1) | NZ516095A (de) |
PL (1) | PL352281A1 (de) |
SK (1) | SK18792001A3 (de) |
TR (1) | TR200103858T2 (de) |
TW (1) | TWI229080B (de) |
UA (1) | UA72923C2 (de) |
WO (1) | WO2001002399A1 (de) |
YU (1) | YU89701A (de) |
ZA (1) | ZA200200017B (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10042655A1 (de) | 2000-08-31 | 2002-03-14 | Aventis Pharma Gmbh | Verfahren zur Herstellung von Inhibitoren der Zell-Adhäsion |
FR2847254B1 (fr) | 2002-11-19 | 2005-01-28 | Aventis Pharma Sa | Nouveaux derives antagonistes du recepteur de la vitronectine, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les refermant |
FR2870541B1 (fr) | 2004-05-18 | 2006-07-14 | Proskelia Sas | Derives de pyrimidines antigonistes du recepteur de la vitronectine |
WO2007089335A2 (en) * | 2005-12-29 | 2007-08-09 | Lexicon Pharmaceutical Inc. | Multicyclic amino acid derivatives and methods of their use |
CL2007002994A1 (es) * | 2006-10-19 | 2008-02-08 | Wyeth Corp | Compuestos derivados heterociclicos que contienen sulfamoilo, inhibidores de hsp90; composicion farmaceutica; y uso para el tratamiento del cancer, tal como cancer de mama, de colon y prostata, entre otros. |
CN107450106A (zh) * | 2017-09-28 | 2017-12-08 | 北京小米移动软件有限公司 | 饮水安全提示方法、装置及智能水杯 |
US11691963B2 (en) | 2020-05-06 | 2023-07-04 | Ajax Therapeutics, Inc. | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors |
EP4267574A1 (de) | 2020-12-23 | 2023-11-01 | Ajax Therapeutics, Inc. | 6-heteroaryloxybenzimidazole und azabenzimidazole als jak2-inhibitoren |
US11970494B2 (en) | 2021-11-09 | 2024-04-30 | Ajax Therapeutics, Inc. | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH10501222A (ja) * | 1994-05-27 | 1998-02-03 | メルク エンド カンパニー インコーポレーテッド | 破骨細胞仲介骨吸収を抑制するための化合物 |
EP0934305A4 (de) * | 1996-08-29 | 2001-04-11 | Merck & Co Inc | Integrinantagonisten |
WO1998018461A1 (en) * | 1996-10-30 | 1998-05-07 | Merck & Co., Inc. | Integrin antagonists |
DE19653646A1 (de) * | 1996-12-20 | 1998-06-25 | Hoechst Ag | Substituierte Purinderivate, Verfahren zu deren Herstellung, sie enthaltende Mittel und deren Verwendung |
WO1998031359A1 (en) * | 1997-01-17 | 1998-07-23 | Merck & Co., Inc. | Integrin antagonists |
JP2002501054A (ja) * | 1998-01-23 | 2002-01-15 | アヴェンティス ファルマ ドイチェラント ゲーエムベーハー | 骨吸収の阻害剤として及び細胞接着の阻害剤としての新規のスルホンアミド誘導体 |
AU2610099A (en) | 1998-01-28 | 1999-08-16 | Danmist Aps | Method of piezoelectrically atomising and pumping fluids and piezoelectric fluidatomising and pumping device |
-
1999
- 1999-07-02 EP EP99112637A patent/EP1065208A1/de not_active Withdrawn
-
2000
- 2000-06-26 KR KR1020017016962A patent/KR20020015997A/ko not_active Application Discontinuation
- 2000-06-26 WO PCT/EP2000/005921 patent/WO2001002399A1/en not_active Application Discontinuation
- 2000-06-26 CZ CZ20014553A patent/CZ20014553A3/cs unknown
- 2000-06-26 UA UA2002020851A patent/UA72923C2/uk unknown
- 2000-06-26 US US10/030,290 patent/US6747016B1/en not_active Expired - Fee Related
- 2000-06-26 ES ES00940406T patent/ES2219353T3/es not_active Expired - Lifetime
- 2000-06-26 EA EA200200121A patent/EA005372B1/ru not_active IP Right Cessation
- 2000-06-26 AT AT00940406T patent/ATE262528T1/de not_active IP Right Cessation
- 2000-06-26 PL PL00352281A patent/PL352281A1/xx not_active Application Discontinuation
- 2000-06-26 HU HU0300183A patent/HUP0300183A3/hu unknown
- 2000-06-26 EE EEP200100713A patent/EE200100713A/xx unknown
- 2000-06-26 DE DE60009296T patent/DE60009296T2/de not_active Expired - Fee Related
- 2000-06-26 BR BR0012050-2A patent/BR0012050A/pt not_active IP Right Cessation
- 2000-06-26 SK SK1879-2001A patent/SK18792001A3/sk unknown
- 2000-06-26 MX MXPA01013241A patent/MXPA01013241A/es active IP Right Grant
- 2000-06-26 EP EP00940406A patent/EP1196416B1/de not_active Expired - Lifetime
- 2000-06-26 TR TR2001/03858T patent/TR200103858T2/xx unknown
- 2000-06-26 JP JP2001507836A patent/JP2003503497A/ja not_active Withdrawn
- 2000-06-26 CA CA002376673A patent/CA2376673A1/en not_active Abandoned
- 2000-06-26 AU AU55349/00A patent/AU774382B2/en not_active Ceased
- 2000-06-26 IL IL14724500A patent/IL147245A0/xx unknown
- 2000-06-26 NZ NZ516095A patent/NZ516095A/en unknown
- 2000-06-26 CN CNB008121001A patent/CN1171888C/zh not_active Expired - Fee Related
- 2000-06-29 MY MYPI20002961A patent/MY122631A/en unknown
- 2000-06-29 AR ARP000103314A patent/AR034242A1/es not_active Application Discontinuation
- 2000-09-01 TW TW089117924A patent/TWI229080B/zh not_active IP Right Cessation
-
2001
- 2001-12-17 BG BG106229A patent/BG106229A/bg unknown
- 2001-12-19 YU YU89701A patent/YU89701A/sh unknown
- 2001-12-28 NO NO20016403A patent/NO20016403L/no not_active Application Discontinuation
-
2002
- 2002-01-02 ZA ZA200200017A patent/ZA200200017B/en unknown
Also Published As
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