BG105865A - 6-o-substituted macrolides having antibacterial activity - Google Patents

6-o-substituted macrolides having antibacterial activity

Info

Publication number
BG105865A
BG105865A BG105865A BG10586501A BG105865A BG 105865 A BG105865 A BG 105865A BG 105865 A BG105865 A BG 105865A BG 10586501 A BG10586501 A BG 10586501A BG 105865 A BG105865 A BG 105865A
Authority
BG
Bulgaria
Prior art keywords
antibacterial activity
macrolides
group
optionally substituted
proviso
Prior art date
Application number
BG105865A
Other languages
Bulgarian (bg)
English (en)
Inventor
Yat OR
Richard Clark
Zhenkun Ma
Michael Rupp
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of BG105865A publication Critical patent/BG105865A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BG105865A 1999-03-15 2001-09-01 6-o-substituted macrolides having antibacterial activity BG105865A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27049799A 1999-03-15 1999-03-15
PCT/US2000/006033 WO2000055168A1 (en) 1999-03-15 2000-03-08 6-o-substituted macrolides having antibacterial activity

Publications (1)

Publication Number Publication Date
BG105865A true BG105865A (en) 2002-05-31

Family

ID=23031548

Family Applications (1)

Application Number Title Priority Date Filing Date
BG105865A BG105865A (en) 1999-03-15 2001-09-01 6-o-substituted macrolides having antibacterial activity

Country Status (25)

Country Link
EP (1) EP1161438B1 (cs)
JP (1) JP2002539217A (cs)
KR (1) KR20020008127A (cs)
CN (1) CN1343215A (cs)
AT (1) ATE266036T1 (cs)
AU (1) AU3517700A (cs)
BG (1) BG105865A (cs)
BR (1) BR0008731A (cs)
CA (1) CA2367431C (cs)
CO (1) CO5271742A1 (cs)
CZ (1) CZ20013223A3 (cs)
DE (1) DE60010442T2 (cs)
DK (1) DK1161438T3 (cs)
ES (1) ES2222189T3 (cs)
HK (1) HK1044157A1 (cs)
HU (1) HUP0201067A3 (cs)
IL (1) IL144542A0 (cs)
NO (1) NO20014380D0 (cs)
NZ (1) NZ513206A (cs)
PL (1) PL350650A1 (cs)
PT (1) PT1161438E (cs)
SK (1) SK13162001A3 (cs)
TR (1) TR200102522T2 (cs)
WO (1) WO2000055168A1 (cs)
ZA (1) ZA200106181B (cs)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1241931C (zh) * 1999-04-16 2006-02-15 高山生物科学股份有限公司 大环内酯抗感染药物
GB0031312D0 (en) 2000-12-21 2001-02-07 Glaxo Group Ltd Macrolides
TWI246515B (en) * 2001-05-30 2006-01-01 Abbott Lab An arylation method for the functionalization of O-allyl erythromycin derivatives
WO2003068791A2 (en) * 2002-02-13 2003-08-21 Abbott Laboratories Macrolides with activity against methicillin-resistant staphylococcus aureus
TWI328009B (en) 2003-05-21 2010-08-01 Glaxo Group Ltd Quinoline derivatives as phosphodiesterase inhibitors
CA2617213C (en) 2005-07-29 2014-01-28 Resverlogix Corp. Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
CA2661017A1 (en) 2006-08-24 2008-02-28 Novartis Ag Organic compounds
US8236835B2 (en) 2006-09-22 2012-08-07 Novartis Ag Heterocyclic inhibitors of stearoyl-CoA desaturase
KR20090091337A (ko) 2006-12-20 2009-08-27 노파르티스 아게 Ｓｃｄ 억제제로서의 ２-치환 ５-원 헤테로사이클
SI2118074T1 (sl) 2007-02-01 2014-05-30 Resverlogix Corp. Spojine za preprečevanje in zdravljenje kardiovaskularnih bolezni
PL2346837T3 (pl) 2008-06-26 2015-07-31 Resverlogix Corp Sposoby wytwarzania pochodnych chinazolinonu
US8952021B2 (en) 2009-01-08 2015-02-10 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular disease
CN105859639A (zh) 2009-03-18 2016-08-17 雷斯韦洛吉克斯公司 新的抗炎剂
SI2421533T1 (sl) 2009-04-22 2019-01-31 Resverlogix Corp. Nova protivnetna sredstva
CN103945848B (zh) 2011-11-01 2016-09-07 雷斯韦洛吉克斯公司 被取代的喹唑啉酮的口服即释制剂
WO2014080290A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Cyclic amines as bromodomain inhibitors
WO2014080291A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Biaryl derivatives as bromodomain inhibitors
CA2895905A1 (en) 2012-12-21 2014-06-26 Zenith Epigenetics Corp. Novel heterocyclic compounds as bromodomain inhibitors
CN104650166B (zh) * 2014-11-17 2017-12-05 广东东阳光药业有限公司 一种大环内酯的制备方法
JO3789B1 (ar) 2015-03-13 2021-01-31 Resverlogix Corp التراكيب والوسائل العلاجية المعتمدة لمعالجة الامراض المتعلقة بالمتممة

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1291352B1 (en) * 1996-09-04 2005-05-25 Abbott Laboratories 6-O-substituted ketolides having antibacterial activity
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців

Also Published As

Publication number Publication date
CN1343215A (zh) 2002-04-03
EP1161438B1 (en) 2004-05-06
ZA200106181B (en) 2002-10-26
CA2367431A1 (en) 2000-09-21
ATE266036T1 (de) 2004-05-15
NZ513206A (en) 2004-02-27
PL350650A1 (en) 2003-01-27
KR20020008127A (ko) 2002-01-29
WO2000055168A1 (en) 2000-09-21
IL144542A0 (en) 2002-05-23
NO20014380L (no) 2001-09-10
DE60010442T2 (de) 2005-05-12
JP2002539217A (ja) 2002-11-19
ES2222189T3 (es) 2005-02-01
SK13162001A3 (sk) 2001-12-03
HUP0201067A3 (en) 2004-07-28
DE60010442D1 (de) 2004-06-09
PT1161438E (pt) 2004-09-30
TR200102522T2 (tr) 2001-12-21
DK1161438T3 (da) 2004-08-30
BR0008731A (pt) 2002-09-24
CA2367431C (en) 2008-06-10
CZ20013223A3 (cs) 2002-01-16
AU3517700A (en) 2000-10-04
HK1044157A1 (zh) 2002-10-11
EP1161438A1 (en) 2001-12-12
CO5271742A1 (es) 2003-04-30
HUP0201067A2 (en) 2002-08-28
NO20014380D0 (no) 2001-09-10

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