BG105583A - Thiourea as inhibitor of herpes viruses - Google Patents
Thiourea as inhibitor of herpes virusesInfo
- Publication number
- BG105583A BG105583A BG105583A BG10558301A BG105583A BG 105583 A BG105583 A BG 105583A BG 105583 A BG105583 A BG 105583A BG 10558301 A BG10558301 A BG 10558301A BG 105583 A BG105583 A BG 105583A
- Authority
- BG
- Bulgaria
- Prior art keywords
- carbon atoms
- alkyl
- atoms
- hydrogen
- perhaloalkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C335/20—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C335/22—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20856198A | 1998-12-09 | 1998-12-09 | |
| PCT/US1999/028837 WO2000034238A1 (en) | 1998-12-09 | 1999-12-06 | Thiourea inhibitors of herpes viruses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG105583A true BG105583A (en) | 2001-12-29 |
Family
ID=22775050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG105583A BG105583A (en) | 1998-12-09 | 2001-06-08 | Thiourea as inhibitor of herpes viruses |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP1137632B1 (pt) |
| JP (1) | JP2002531545A (pt) |
| KR (1) | KR20010089559A (pt) |
| CN (1) | CN1332725A (pt) |
| AR (1) | AR033789A1 (pt) |
| AT (1) | ATE272052T1 (pt) |
| AU (1) | AU1934500A (pt) |
| BG (1) | BG105583A (pt) |
| BR (1) | BR9916086A (pt) |
| CA (1) | CA2351403A1 (pt) |
| CZ (1) | CZ20011957A3 (pt) |
| DE (1) | DE69919023T2 (pt) |
| DK (1) | DK1137632T3 (pt) |
| EA (1) | EA200100634A1 (pt) |
| ES (1) | ES2224733T3 (pt) |
| HU (1) | HUP0104763A3 (pt) |
| ID (1) | ID30287A (pt) |
| IL (1) | IL143262A0 (pt) |
| NO (1) | NO20012838L (pt) |
| NZ (1) | NZ512108A (pt) |
| PL (1) | PL348178A1 (pt) |
| PT (1) | PT1137632E (pt) |
| SK (1) | SK7702001A3 (pt) |
| TR (1) | TR200101597T2 (pt) |
| WO (1) | WO2000034238A1 (pt) |
| ZA (1) | ZA200104144B (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6844367B1 (en) | 1999-09-17 | 2005-01-18 | Millennium Pharmaceuticals, Inc. | Benzamides and related inhibitors of factor Xa |
| DK1259485T3 (da) | 2000-02-29 | 2006-04-10 | Millennium Pharm Inc | Benzamider og beslægtede inhibitorer for faktor Xa |
| DE10217518A1 (de) * | 2002-04-19 | 2003-11-06 | Bayer Ag | Lactone |
| DE10222024A1 (de) * | 2002-05-17 | 2003-11-27 | Bayer Ag | Lactame |
| DE10257786A1 (de) * | 2002-12-11 | 2004-07-01 | Bayer Healthcare Ag | Oxazolidinone |
| PT2077995E (pt) | 2006-11-02 | 2012-05-10 | Millennium Pharm Inc | Métodos de sintetizar sais farmacêuticos de um inibidor de fator xa |
| EP2714941A4 (en) * | 2011-05-24 | 2014-12-03 | Wistar Inst | COMPOSITIONS AND METHODS FOR MODULATING THE EFFECT OF THE EPSTEIN-BARR NUCLEAR ANTIGEN 1 |
| WO2014070978A1 (en) * | 2012-11-03 | 2014-05-08 | Boehringer Ingelheim International Gmbh | Inhibitors of cytomegalovirus |
| WO2014070979A1 (en) * | 2012-11-03 | 2014-05-08 | Boehringer Ingelheim International Gmbh | Inhibitors of cytomegalovirus |
| WO2022150962A1 (en) * | 2021-01-12 | 2022-07-21 | Westlake Pharmaceutical (Hangzhou) Co., Ltd. | Protease inhibitors, preparation, and uses thereof |
| AU2022343340A1 (en) * | 2021-09-07 | 2024-03-28 | Qilu Animal Health Products Co., Ltd. | 3clpro protease inhibitor |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU210683B (en) * | 1990-06-18 | 1995-06-28 | Sandoz Ag | Process for producing n-benzyl-n1-(phenyl-alkyl)-thiourea derivatives and pharmaceutical compositions containing the same |
| WO1996025157A1 (en) * | 1995-02-17 | 1996-08-22 | Smithkline Beecham Corporation | Il-8 receptor antagonists |
| GB9519270D0 (en) * | 1995-09-21 | 1995-11-22 | Sandoz Pharma Uk | Organic compounds |
| CN1515248A (zh) * | 1996-04-23 | 2004-07-28 | ��̩��˹ҩ��ɷ�����˾ | 用作肌苷-5'-一磷酸脱氢酶抑制剂的脲衍生物 |
-
1999
- 1999-12-06 AU AU19345/00A patent/AU1934500A/en not_active Abandoned
- 1999-12-06 IL IL14326299A patent/IL143262A0/xx unknown
- 1999-12-06 KR KR1020017007134A patent/KR20010089559A/ko not_active Application Discontinuation
- 1999-12-06 BR BR9916086-2A patent/BR9916086A/pt not_active Application Discontinuation
- 1999-12-06 NZ NZ512108A patent/NZ512108A/en unknown
- 1999-12-06 SK SK770-2001A patent/SK7702001A3/sk unknown
- 1999-12-06 DE DE69919023T patent/DE69919023T2/de not_active Expired - Fee Related
- 1999-12-06 CN CN99815344A patent/CN1332725A/zh active Pending
- 1999-12-06 AT AT99963021T patent/ATE272052T1/de not_active IP Right Cessation
- 1999-12-06 CZ CZ20011957A patent/CZ20011957A3/cs unknown
- 1999-12-06 EP EP99963021A patent/EP1137632B1/en not_active Expired - Lifetime
- 1999-12-06 TR TR2001/01597T patent/TR200101597T2/xx unknown
- 1999-12-06 EA EA200100634A patent/EA200100634A1/ru unknown
- 1999-12-06 CA CA002351403A patent/CA2351403A1/en not_active Abandoned
- 1999-12-06 PL PL99348178A patent/PL348178A1/xx not_active Application Discontinuation
- 1999-12-06 ID IDW00200101228A patent/ID30287A/id unknown
- 1999-12-06 DK DK99963021T patent/DK1137632T3/da active
- 1999-12-06 HU HU0104763A patent/HUP0104763A3/hu unknown
- 1999-12-06 JP JP2000586686A patent/JP2002531545A/ja active Pending
- 1999-12-06 WO PCT/US1999/028837 patent/WO2000034238A1/en not_active Application Discontinuation
- 1999-12-06 ES ES99963021T patent/ES2224733T3/es not_active Expired - Lifetime
- 1999-12-06 PT PT99963021T patent/PT1137632E/pt unknown
- 1999-12-07 AR ARP990106229A patent/AR033789A1/es not_active Application Discontinuation
-
2001
- 2001-05-21 ZA ZA200104144A patent/ZA200104144B/xx unknown
- 2001-06-08 NO NO20012838A patent/NO20012838L/no not_active Application Discontinuation
- 2001-06-08 BG BG105583A patent/BG105583A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU1934500A (en) | 2000-06-26 |
| WO2000034238A1 (en) | 2000-06-15 |
| NZ512108A (en) | 2003-09-26 |
| BR9916086A (pt) | 2001-09-04 |
| HUP0104763A2 (hu) | 2002-04-29 |
| CA2351403A1 (en) | 2000-06-15 |
| HUP0104763A3 (en) | 2005-04-28 |
| TR200101597T2 (tr) | 2001-10-22 |
| ES2224733T3 (es) | 2005-03-01 |
| PL348178A1 (en) | 2002-05-06 |
| DK1137632T3 (da) | 2004-11-01 |
| EP1137632A1 (en) | 2001-10-04 |
| SK7702001A3 (en) | 2002-04-04 |
| EP1137632B1 (en) | 2004-07-28 |
| ID30287A (id) | 2001-11-15 |
| JP2002531545A (ja) | 2002-09-24 |
| ZA200104144B (en) | 2002-08-21 |
| KR20010089559A (ko) | 2001-10-06 |
| EA200100634A1 (ru) | 2001-10-22 |
| NO20012838L (no) | 2001-08-08 |
| ATE272052T1 (de) | 2004-08-15 |
| CN1332725A (zh) | 2002-01-23 |
| DE69919023T2 (de) | 2005-07-28 |
| CZ20011957A3 (cs) | 2001-10-17 |
| AR033789A1 (es) | 2004-01-07 |
| NO20012838D0 (no) | 2001-06-08 |
| DE69919023D1 (de) | 2004-09-02 |
| PT1137632E (pt) | 2004-11-30 |
| IL143262A0 (en) | 2002-04-21 |
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