DK1137632T3 - Thiourinstofinhibitorer af herpesvira - Google Patents
Thiourinstofinhibitorer af herpesviraInfo
- Publication number
- DK1137632T3 DK1137632T3 DK99963021T DK99963021T DK1137632T3 DK 1137632 T3 DK1137632 T3 DK 1137632T3 DK 99963021 T DK99963021 T DK 99963021T DK 99963021 T DK99963021 T DK 99963021T DK 1137632 T3 DK1137632 T3 DK 1137632T3
- Authority
- DK
- Denmark
- Prior art keywords
- herpes viruses
- thiourea inhibitors
- thiourea
- inhibitors
- herpes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C335/20—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C335/22—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20856198A | 1998-12-09 | 1998-12-09 | |
EP99963021A EP1137632B1 (en) | 1998-12-09 | 1999-12-06 | Thiourea inhibitors of herpes viruses |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1137632T3 true DK1137632T3 (da) | 2004-11-01 |
Family
ID=22775050
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99963021T DK1137632T3 (da) | 1998-12-09 | 1999-12-06 | Thiourinstofinhibitorer af herpesvira |
Country Status (26)
Country | Link |
---|---|
EP (1) | EP1137632B1 (pt) |
JP (1) | JP2002531545A (pt) |
KR (1) | KR20010089559A (pt) |
CN (1) | CN1332725A (pt) |
AR (1) | AR033789A1 (pt) |
AT (1) | ATE272052T1 (pt) |
AU (1) | AU1934500A (pt) |
BG (1) | BG105583A (pt) |
BR (1) | BR9916086A (pt) |
CA (1) | CA2351403A1 (pt) |
CZ (1) | CZ20011957A3 (pt) |
DE (1) | DE69919023T2 (pt) |
DK (1) | DK1137632T3 (pt) |
EA (1) | EA200100634A1 (pt) |
ES (1) | ES2224733T3 (pt) |
HU (1) | HUP0104763A3 (pt) |
ID (1) | ID30287A (pt) |
IL (1) | IL143262A0 (pt) |
NO (1) | NO20012838L (pt) |
NZ (1) | NZ512108A (pt) |
PL (1) | PL348178A1 (pt) |
PT (1) | PT1137632E (pt) |
SK (1) | SK7702001A3 (pt) |
TR (1) | TR200101597T2 (pt) |
WO (1) | WO2000034238A1 (pt) |
ZA (1) | ZA200104144B (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6844367B1 (en) | 1999-09-17 | 2005-01-18 | Millennium Pharmaceuticals, Inc. | Benzamides and related inhibitors of factor Xa |
US6376515B2 (en) | 2000-02-29 | 2002-04-23 | Cor Therapeutics, Inc. | Benzamides and related inhibitors of factor Xa |
DE10217518A1 (de) * | 2002-04-19 | 2003-11-06 | Bayer Ag | Lactone |
DE10222024A1 (de) * | 2002-05-17 | 2003-11-27 | Bayer Ag | Lactame |
DE10257786A1 (de) * | 2002-12-11 | 2004-07-01 | Bayer Healthcare Ag | Oxazolidinone |
EP2077995B1 (en) | 2006-11-02 | 2012-02-08 | Millennium Pharmaceuticals, Inc. | Methods of synthesizing pharmaceutical salts of a factor xa inhibitor |
US9309212B2 (en) | 2011-05-24 | 2016-04-12 | The Wistar Institute | Compositions and methods for modulating the activity of Epstein-Barr nuclear antigen 1 |
WO2014070979A1 (en) * | 2012-11-03 | 2014-05-08 | Boehringer Ingelheim International Gmbh | Inhibitors of cytomegalovirus |
US9284310B2 (en) | 2012-11-03 | 2016-03-15 | Boehringer Ingelheim International Gmbh | Inhibitors of cytomegalovirus |
WO2022150962A1 (en) * | 2021-01-12 | 2022-07-21 | Westlake Pharmaceutical (Hangzhou) Co., Ltd. | Protease inhibitors, preparation, and uses thereof |
EP4400497A1 (en) * | 2021-09-07 | 2024-07-17 | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. | 3clpro protease inhibitor |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU210683B (en) * | 1990-06-18 | 1995-06-28 | Sandoz Ag | Process for producing n-benzyl-n1-(phenyl-alkyl)-thiourea derivatives and pharmaceutical compositions containing the same |
WO1996025157A1 (en) * | 1995-02-17 | 1996-08-22 | Smithkline Beecham Corporation | Il-8 receptor antagonists |
GB9519270D0 (en) * | 1995-09-21 | 1995-11-22 | Sandoz Pharma Uk | Organic compounds |
AU723730B2 (en) * | 1996-04-23 | 2000-09-07 | Vertex Pharmaceuticals Incorporated | Urea derivatives as inhibitors of IMPDH enzyme |
-
1999
- 1999-12-06 ES ES99963021T patent/ES2224733T3/es not_active Expired - Lifetime
- 1999-12-06 DK DK99963021T patent/DK1137632T3/da active
- 1999-12-06 BR BR9916086-2A patent/BR9916086A/pt not_active Application Discontinuation
- 1999-12-06 CA CA002351403A patent/CA2351403A1/en not_active Abandoned
- 1999-12-06 EA EA200100634A patent/EA200100634A1/ru unknown
- 1999-12-06 DE DE69919023T patent/DE69919023T2/de not_active Expired - Fee Related
- 1999-12-06 JP JP2000586686A patent/JP2002531545A/ja active Pending
- 1999-12-06 AT AT99963021T patent/ATE272052T1/de not_active IP Right Cessation
- 1999-12-06 AU AU19345/00A patent/AU1934500A/en not_active Abandoned
- 1999-12-06 CZ CZ20011957A patent/CZ20011957A3/cs unknown
- 1999-12-06 NZ NZ512108A patent/NZ512108A/en unknown
- 1999-12-06 KR KR1020017007134A patent/KR20010089559A/ko not_active Application Discontinuation
- 1999-12-06 CN CN99815344A patent/CN1332725A/zh active Pending
- 1999-12-06 PL PL99348178A patent/PL348178A1/xx not_active Application Discontinuation
- 1999-12-06 EP EP99963021A patent/EP1137632B1/en not_active Expired - Lifetime
- 1999-12-06 SK SK770-2001A patent/SK7702001A3/sk unknown
- 1999-12-06 HU HU0104763A patent/HUP0104763A3/hu unknown
- 1999-12-06 PT PT99963021T patent/PT1137632E/pt unknown
- 1999-12-06 WO PCT/US1999/028837 patent/WO2000034238A1/en not_active Application Discontinuation
- 1999-12-06 TR TR2001/01597T patent/TR200101597T2/xx unknown
- 1999-12-06 ID IDW00200101228A patent/ID30287A/id unknown
- 1999-12-06 IL IL14326299A patent/IL143262A0/xx unknown
- 1999-12-07 AR ARP990106229A patent/AR033789A1/es not_active Application Discontinuation
-
2001
- 2001-05-21 ZA ZA200104144A patent/ZA200104144B/xx unknown
- 2001-06-08 NO NO20012838A patent/NO20012838L/no not_active Application Discontinuation
- 2001-06-08 BG BG105583A patent/BG105583A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
HUP0104763A2 (hu) | 2002-04-29 |
ATE272052T1 (de) | 2004-08-15 |
EP1137632B1 (en) | 2004-07-28 |
DE69919023T2 (de) | 2005-07-28 |
AR033789A1 (es) | 2004-01-07 |
PT1137632E (pt) | 2004-11-30 |
HUP0104763A3 (en) | 2005-04-28 |
EP1137632A1 (en) | 2001-10-04 |
DE69919023D1 (de) | 2004-09-02 |
BR9916086A (pt) | 2001-09-04 |
WO2000034238A1 (en) | 2000-06-15 |
NZ512108A (en) | 2003-09-26 |
EA200100634A1 (ru) | 2001-10-22 |
AU1934500A (en) | 2000-06-26 |
IL143262A0 (en) | 2002-04-21 |
KR20010089559A (ko) | 2001-10-06 |
NO20012838D0 (no) | 2001-06-08 |
NO20012838L (no) | 2001-08-08 |
ID30287A (id) | 2001-11-15 |
CZ20011957A3 (cs) | 2001-10-17 |
CN1332725A (zh) | 2002-01-23 |
SK7702001A3 (en) | 2002-04-04 |
CA2351403A1 (en) | 2000-06-15 |
JP2002531545A (ja) | 2002-09-24 |
ES2224733T3 (es) | 2005-03-01 |
ZA200104144B (en) | 2002-08-21 |
BG105583A (en) | 2001-12-29 |
TR200101597T2 (tr) | 2001-10-22 |
PL348178A1 (en) | 2002-05-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1064298T3 (da) | Inhibitorer af caspaser | |
DK1049662T3 (da) | Inhibitorer af alpha4-medieret celleadhæsion | |
DK1077943T3 (da) | Heterocykliske inhibitorer af p38 | |
PT945443E (pt) | Derivados de pirimidina inibidores de hiv | |
DK1042307T3 (da) | Aminothiazolinhibitorer af cyclinafhængige kinaser | |
DK1117669T3 (da) | Antiviruspurinderivater | |
DE69905683D1 (de) | Pyrimidineihibitoren der HIV-Replikation | |
DK1183033T3 (da) | Pyrrolotriazininhibitorer af kinaser | |
PT1114051E (pt) | Inibidores de p38 | |
DE69941116D1 (de) | G von gdf-8 | |
DK1107980T3 (da) | Krystallinske former af EtO2C-CH2-(R)Cgl-Aze-Pab-OH | |
DK1047450T3 (da) | Kombinationer af ACE-inhibitorer og MMP-inhibitorer | |
DK0878418T3 (da) | Opbygning af transportør med sidebøjning | |
IS5772A (is) | Þalazín (phthalazine) afleiður af fosfódíesterasa4 lötum | |
DK1137632T3 (da) | Thiourinstofinhibitorer af herpesvira | |
NO20012834D0 (no) | Acetamid- og substituerte acetamid-holdige tioureainhibitorer for herpesvirus | |
ATE252547T1 (de) | Matrixmetalloproteinaseinhibitoren | |
ID28032A (id) | TRISIKLIK PIPERIDIN-Δ3-SEBAGAI ANTAGONIS-α2 | |
DK1155050T3 (da) | Fremstilling af polyolefin | |
DK1137645T3 (da) | Alfa-methylbenzylholdige thiourinstofinhibitorer af herpesvira indeholdende en phenylendiamingruppe | |
DK1102747T3 (da) | Krystalformer af osenetant | |
NO20012836D0 (no) | Tiourea-inhibitorer for herpes virus | |
NO20012837D0 (no) | Tiourea-inhibitorer for herpesvirus | |
DK1088010T3 (da) | Fremstilling af polyolefiner | |
DE59910200D1 (de) | Kühlbares Bauteil |