BG105079A - Глюкаконоподобен пептид - 1 за усъвършенстване бета - клетъчния отвор спрямо глюкоза в субекти с увреден глюкозен толеранс - Google Patents
Глюкаконоподобен пептид - 1 за усъвършенстване бета - клетъчния отвор спрямо глюкоза в субекти с увреден глюкозен толерансInfo
- Publication number
- BG105079A BG105079A BG105079A BG10507900A BG105079A BG 105079 A BG105079 A BG 105079A BG 105079 A BG105079 A BG 105079A BG 10507900 A BG10507900 A BG 10507900A BG 105079 A BG105079 A BG 105079A
- Authority
- BG
- Bulgaria
- Prior art keywords
- glucagon
- peptide
- subjects
- glucose
- cell response
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Изобретението се отнася до състав за лечение на увреден глюкозен толеранс (IGT), включващ съединение, което се свързва към рецептор за глюкагоноподобен пептид-1, и фармацевтичен носител. Количествотона присъстващото съединение е ефективно за усъвършенстване на панкреатичната бета-клетъчна чувствителност за нивата на кръвна глюкоза при хора с IGT.Изобретението се отнася и до метод за подобряване образците на инсулинови секреторни отговори при хора с IGT чрез прилагане на състав, включващ съединение, което се свързва към рецептор за глюкагоноподобен пептид-1 и фармацевтичен носител.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8904498P | 1998-06-12 | 1998-06-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
BG105079A true BG105079A (bg) | 2001-09-28 |
BG64975B1 BG64975B1 (bg) | 2006-11-30 |
Family
ID=22215287
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG105079A BG64975B1 (bg) | 1998-06-12 | 2000-12-21 | Екзендин и екзендинови аналози за усъвършенстванена бета-клетъчния отговор спрямо глюкоза в субектс увреден глюкозен толеранс |
Country Status (30)
Country | Link |
---|---|
US (1) | US7265087B1 (bg) |
EP (2) | EP1419783A3 (bg) |
JP (1) | JP2002517469A (bg) |
KR (1) | KR20010052800A (bg) |
CN (1) | CN1209166C (bg) |
AP (1) | AP2001002027A0 (bg) |
AT (1) | ATE270897T1 (bg) |
AU (2) | AU758825B2 (bg) |
BG (1) | BG64975B1 (bg) |
BR (1) | BR9911112A (bg) |
CA (1) | CA2334872C (bg) |
CZ (1) | CZ294848B6 (bg) |
DE (1) | DE69918691T2 (bg) |
DK (1) | DK1083924T3 (bg) |
EA (1) | EA004538B1 (bg) |
ES (1) | ES2224659T3 (bg) |
GE (1) | GEP20033015B (bg) |
HU (1) | HUP0102193A2 (bg) |
ID (1) | ID28617A (bg) |
IL (2) | IL140223A0 (bg) |
MX (1) | MXPA00012286A (bg) |
NO (1) | NO20006336L (bg) |
NZ (2) | NZ508823A (bg) |
OA (1) | OA11694A (bg) |
PL (1) | PL195662B1 (bg) |
PT (1) | PT1083924E (bg) |
SK (1) | SK19042000A3 (bg) |
TR (1) | TR200100079T2 (bg) |
UA (1) | UA69412C2 (bg) |
WO (1) | WO1999064061A1 (bg) |
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US20020025306A1 (en) * | 2000-01-07 | 2002-02-28 | Baetge Edward E. | Methods of increasing the glucose responsiveness of pancreatic ss-cells |
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WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
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JPWO2006126688A1 (ja) * | 2005-05-27 | 2008-12-25 | アスビオファーマ株式会社 | インスリン抵抗性改善剤 |
KR101557502B1 (ko) | 2005-09-14 | 2015-10-06 | 맨카인드 코포레이션 | 결정질 미립자 표면에 대한 활성제의 친화력의 증가를기반으로 하는 약물 제제의 방법 |
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MX2008013304A (es) | 2006-04-20 | 2008-10-27 | Amgen Inc | Compuestos de peptido 1 tipo glucagon. |
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RU2413528C2 (ru) | 2007-01-18 | 2011-03-10 | Открытое Акционерное Общество "Валента Фармацевтика" | Лекарственный препарат для лечения сахарного диабета на основе экзенатида и даларгина, применение и способ лечения |
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CN110225762A (zh) | 2017-01-03 | 2019-09-10 | 因塔西亚制药公司 | 包括glp-1受体激动剂的连续施用和药物的共同施用的方法 |
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EP0915910B1 (de) | 1996-06-05 | 2006-01-18 | Roche Diagnostics GmbH | Exendin-analoga, verfahren zu deren herstellung und diese enthaltende arzneimittel |
US6277819B1 (en) | 1996-08-30 | 2001-08-21 | Eli Lilly And Company | Use of GLP-1 or analogs in treatment of myocardial infarction |
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-
1999
- 1999-05-07 AU AU38899/99A patent/AU758825B2/en not_active Ceased
- 1999-05-07 NZ NZ508823A patent/NZ508823A/en not_active IP Right Cessation
- 1999-05-07 WO PCT/US1999/010040 patent/WO1999064061A1/en not_active Application Discontinuation
- 1999-05-07 AT AT99921778T patent/ATE270897T1/de not_active IP Right Cessation
- 1999-05-07 TR TR2001/00079T patent/TR200100079T2/xx unknown
- 1999-05-07 BR BR9911112-8A patent/BR9911112A/pt not_active IP Right Cessation
- 1999-05-07 ES ES99921778T patent/ES2224659T3/es not_active Expired - Lifetime
- 1999-05-07 CN CNB998091812A patent/CN1209166C/zh not_active Expired - Fee Related
- 1999-05-07 CA CA2334872A patent/CA2334872C/en not_active Expired - Fee Related
- 1999-05-07 EP EP04075402A patent/EP1419783A3/en not_active Withdrawn
- 1999-05-07 US US09/719,410 patent/US7265087B1/en not_active Expired - Fee Related
- 1999-05-07 AP APAP/P/2001/002027A patent/AP2001002027A0/en unknown
- 1999-05-07 PL PL99345212A patent/PL195662B1/pl unknown
- 1999-05-07 HU HU0102193A patent/HUP0102193A2/hu unknown
- 1999-05-07 MX MXPA00012286A patent/MXPA00012286A/es unknown
- 1999-05-07 OA OA1200000341A patent/OA11694A/en unknown
- 1999-05-07 EA EA200100029A patent/EA004538B1/ru not_active IP Right Cessation
- 1999-05-07 JP JP2000553129A patent/JP2002517469A/ja active Pending
- 1999-05-07 KR KR1020007014110A patent/KR20010052800A/ko not_active Application Discontinuation
- 1999-05-07 NZ NZ527473A patent/NZ527473A/en not_active IP Right Cessation
- 1999-05-07 SK SK1904-2000A patent/SK19042000A3/sk unknown
- 1999-05-07 GE GEAP19995661A patent/GEP20033015B/en unknown
- 1999-05-07 DK DK99921778T patent/DK1083924T3/da active
- 1999-05-07 EP EP99921778A patent/EP1083924B1/en not_active Revoked
- 1999-05-07 IL IL14022399A patent/IL140223A0/xx unknown
- 1999-05-07 DE DE69918691T patent/DE69918691T2/de not_active Revoked
- 1999-05-07 PT PT99921778T patent/PT1083924E/pt unknown
- 1999-05-07 CZ CZ20004614A patent/CZ294848B6/cs not_active IP Right Cessation
- 1999-05-07 ID IDW20010100A patent/ID28617A/id unknown
- 1999-07-05 UA UA2000127165A patent/UA69412C2/uk unknown
-
2000
- 2000-12-11 IL IL140223A patent/IL140223A/en not_active IP Right Cessation
- 2000-12-12 NO NO20006336A patent/NO20006336L/no not_active Application Discontinuation
- 2000-12-21 BG BG105079A patent/BG64975B1/bg unknown
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2003
- 2003-07-03 AU AU2003212050A patent/AU2003212050B2/en not_active Ceased
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