BG104076A - Комбинирано лечение включващо амплодипин и статиново съединение - Google Patents
Комбинирано лечение включващо амплодипин и статиново съединениеInfo
- Publication number
- BG104076A BG104076A BG104076A BG10407600A BG104076A BG 104076 A BG104076 A BG 104076A BG 104076 A BG104076 A BG 104076A BG 10407600 A BG10407600 A BG 10407600A BG 104076 A BG104076 A BG 104076A
- Authority
- BG
- Bulgaria
- Prior art keywords
- combinations
- pharmaceutically acceptable
- patients
- amplodipin
- statine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Electrotherapy Devices (AREA)
- Iron Core Of Rotating Electric Machines (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Изобретението се отнася до фармацевтични комбинации на амлодипин или негова фармацевтично приемлива, присъединителна с киселина сол, и статини и техни фармацевтично приемливи соли, съдържащи такива комбинации, до китове, включващи такива комбинации,и до методи за тяхното използване при лечение на пациенти, страдащи от ангина пекторис, атеросклероза, комбинация от високо кръвно налягане с хиперлипидемия и на пациенти с риск от сърдечни заболявания. Изобретението се отнася също и до сумарни и синергитични комбинации на амлодипин или негова фармацевтично приемлива, присъединителна с киселина сол и статини и техни фармацевтично приемливи соли, които комбинации са приложими при лечение на пациенти, страдащи от ангина пекторис, атеросклероза, комбинация на хипертония с хиперлипидемия, както и на пациенти със симптоми за риск от сърдечни заболявания.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5755597P | 1997-08-29 | 1997-08-29 | |
PCT/IB1998/001220 WO1999011263A1 (en) | 1997-08-29 | 1998-08-10 | Combination therapy comprising amlodipine and a statin compound |
Publications (1)
Publication Number | Publication Date |
---|---|
BG104076A true BG104076A (bg) | 2000-09-29 |
Family
ID=22011309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG104076A BG104076A (bg) | 1997-08-29 | 2000-01-13 | Комбинирано лечение включващо амплодипин и статиново съединение |
Country Status (37)
Country | Link |
---|---|
US (1) | US20020025981A1 (bg) |
EP (1) | EP1003507A1 (bg) |
JP (1) | JP2001514224A (bg) |
KR (1) | KR20010022385A (bg) |
CN (1) | CN1117566C (bg) |
AP (1) | AP1207A (bg) |
AR (1) | AR017514A1 (bg) |
AU (1) | AU744982B2 (bg) |
BG (1) | BG104076A (bg) |
BR (1) | BR9811558A (bg) |
CA (1) | CA2296726C (bg) |
CO (1) | CO4970726A1 (bg) |
DZ (1) | DZ2600A1 (bg) |
EA (1) | EA002705B1 (bg) |
GT (1) | GT199800134A (bg) |
HK (1) | HK1029530A1 (bg) |
HN (1) | HN1998000124A (bg) |
HR (1) | HRP980475A2 (bg) |
HU (1) | HUP0003103A3 (bg) |
ID (1) | ID24275A (bg) |
IL (2) | IL133957A0 (bg) |
IS (1) | IS5345A (bg) |
MA (1) | MA26539A1 (bg) |
NO (1) | NO20000999L (bg) |
NZ (1) | NZ502283A (bg) |
OA (1) | OA11289A (bg) |
PA (1) | PA8457201A1 (bg) |
PE (1) | PE106999A1 (bg) |
PL (1) | PL339088A1 (bg) |
SA (1) | SA98190432A (bg) |
SK (1) | SK1392000A3 (bg) |
TN (1) | TNSN98158A1 (bg) |
TR (1) | TR200000562T2 (bg) |
UY (1) | UY25159A1 (bg) |
WO (1) | WO1999011263A1 (bg) |
YU (1) | YU2700A (bg) |
ZA (1) | ZA987843B (bg) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1076091A1 (en) * | 1999-08-09 | 2001-02-14 | Universite Catholique De Louvain | Medicament for the prevention and/or the treatment of ischemic heart and peripheral vascular diseases, tumour and wounds |
DE19944803A1 (de) * | 1999-09-20 | 2001-03-29 | Bayer Ag | Kombination von Dihydropyridinverbindungen und HMG-CoA-Reduktase-Inhibitoren und ihre Verwendung in Arzneimitteln |
AU2001284413A1 (en) * | 2000-08-30 | 2002-03-13 | Sankyo Company Limited | Medicinal compositions for preventing or treating heart failure |
AUPR255401A0 (en) * | 2001-01-16 | 2001-02-08 | Novogen Research Pty Ltd | Regulation of lipids and/or bone density and compositions therefor |
US20030114497A1 (en) * | 2001-07-31 | 2003-06-19 | Laman Alani | Pharmaceutical compositions of amlodipine and atorvastatin |
NL1019882C2 (nl) * | 2002-02-01 | 2003-08-04 | Synthon Licensing | Amlodipine vrije base. |
US20040053842A1 (en) * | 2002-07-02 | 2004-03-18 | Pfizer Inc. | Methods of treatment with CETP inhibitors and antihypertensive agents |
US7071210B2 (en) * | 2002-07-02 | 2006-07-04 | Pfizer Inc. | CETP inhibitors in combination with antihypertensive agents and uses thereof |
GB0322552D0 (en) | 2003-09-26 | 2003-10-29 | Astrazeneca Uk Ltd | Therapeutic treatment |
WO2005097191A2 (en) * | 2004-04-04 | 2005-10-20 | Sepracor Inc. | COMBINATIONS COMPRISING (S)- AMLODIPINE AND A HMG-CoA REDUCTASE INHIBITOR OR CHOLESTEROL ABSORPOTION INHIBITOR OR BOTH, AND METHODS FOR REDUCING HYPERTENSION |
KR100582347B1 (ko) * | 2004-12-30 | 2006-05-22 | 한미약품 주식회사 | 3-하이드록시-3-메틸글루타릴 조효소 a 환원효소 억제제및 고혈압 치료제의 복합제제 및 그의 제조방법 |
KR100742432B1 (ko) | 2005-12-27 | 2007-07-24 | 한미약품 주식회사 | 암로디핀 캠실레이트 및 심바스타틴을 포함하는 복합제제,및 이의 제조방법 |
EP2000137B1 (en) | 2006-03-29 | 2015-10-21 | Kowa Company, Ltd. | Triglyceride-lowering agent and hyperinsulinism-ameliorating agent |
WO2008023958A1 (en) * | 2006-08-24 | 2008-02-28 | Hanall Pharmaceutical Co., Ltd. | Combined pharmaceutical formulation with controlled-release comprising dihydropyridine calcium channel blockers and hmg-coa reductase inhibitors |
WO2008023869A1 (en) * | 2006-08-24 | 2008-02-28 | Hanall Pharmaceutical Co., Ltd. | Combined pharmeceutical formulation with controlled-release comprising dihydropyridine calcium channel blockers and hmg-coa reductase inhibitors |
MX2007008440A (es) * | 2007-07-11 | 2009-02-18 | Senosiain S A De C V Lab | Composicion farmaceutica combinada. |
KR101181172B1 (ko) * | 2008-02-22 | 2012-09-18 | 한올바이오파마주식회사 | 방출성이 제어된 시간차 투여 약제학적 제제 |
WO2009125987A2 (ko) * | 2008-04-10 | 2009-10-15 | 한올제약주식회사 | 약제학적 제제 |
WO2010008203A2 (ko) * | 2008-07-15 | 2010-01-21 | 한올제약주식회사 | 칼슘채널길항제를 포함하는 약제학적 제제 |
CN101804055B (zh) * | 2010-04-27 | 2012-01-25 | 施慧达药业集团(吉林)有限公司 | 复方药物制剂 |
TW201628625A (zh) * | 2015-02-06 | 2016-08-16 | 英特賽普醫藥品公司 | 組合療法醫藥組成物 |
EP3706799A4 (en) * | 2017-11-10 | 2021-08-25 | Op-T Llc | PROCEDURES FOR THE PREVENTION, MODULATION AND / OR REDUCTION OF CARDIOVASCULAR DISEASES |
US11793854B2 (en) | 2019-03-21 | 2023-10-24 | Op-T Llc | Methods for reducing symptoms of multiple sclerosis using a six-amino acid long peptide that inhibits CD40-CD150 interaction |
WO2021108343A1 (en) * | 2019-11-25 | 2021-06-03 | Fordoz Pharma C0Rp. | Formulations comprising lipid-lowering and blood pressure-lowering drugs |
CN112826937B (zh) * | 2021-03-25 | 2022-03-22 | 山东大学齐鲁医院 | 艾地苯醌与他汀类药物联用在防治动脉粥样硬化中的应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN176897B (bg) * | 1993-10-29 | 1996-09-28 | Cadila Lab Ltd | |
DE19539363A1 (de) * | 1995-10-23 | 1997-04-24 | Basf Ag | Verfahren zur Herstellung von festen Arzneiformen |
-
1998
- 1998-08-10 CN CN98808465A patent/CN1117566C/zh not_active Expired - Fee Related
- 1998-08-10 ID IDW20000199A patent/ID24275A/id unknown
- 1998-08-10 YU YU2700A patent/YU2700A/sh unknown
- 1998-08-10 EP EP98935246A patent/EP1003507A1/en not_active Withdrawn
- 1998-08-10 PL PL98339088A patent/PL339088A1/xx unknown
- 1998-08-10 IL IL13395798A patent/IL133957A0/xx unknown
- 1998-08-10 HU HU0003103A patent/HUP0003103A3/hu unknown
- 1998-08-10 NZ NZ502283A patent/NZ502283A/en unknown
- 1998-08-10 KR KR1020007000964A patent/KR20010022385A/ko not_active Application Discontinuation
- 1998-08-10 CA CA002296726A patent/CA2296726C/en not_active Expired - Fee Related
- 1998-08-10 TR TR2000/00562T patent/TR200000562T2/xx unknown
- 1998-08-10 HN HN1998000124A patent/HN1998000124A/es unknown
- 1998-08-10 SK SK139-2000A patent/SK1392000A3/sk unknown
- 1998-08-10 EA EA200000013A patent/EA002705B1/ru not_active IP Right Cessation
- 1998-08-10 AP APAP/P/1998/001333A patent/AP1207A/en active
- 1998-08-10 WO PCT/IB1998/001220 patent/WO1999011263A1/en not_active Application Discontinuation
- 1998-08-10 AU AU84585/98A patent/AU744982B2/en not_active Ceased
- 1998-08-10 JP JP2000508366A patent/JP2001514224A/ja active Pending
- 1998-08-10 BR BR9811558-8A patent/BR9811558A/pt not_active Application Discontinuation
- 1998-08-11 PA PA19988457201A patent/PA8457201A1/es unknown
- 1998-08-17 GT GT199800134A patent/GT199800134A/es unknown
- 1998-08-19 SA SA98190432A patent/SA98190432A/ar unknown
- 1998-08-24 PE PE1998000768A patent/PE106999A1/es not_active Application Discontinuation
- 1998-08-26 TN TNTNSN98158A patent/TNSN98158A1/fr unknown
- 1998-08-26 DZ DZ980210A patent/DZ2600A1/xx active
- 1998-08-26 MA MA25231A patent/MA26539A1/fr unknown
- 1998-08-27 CO CO98049137A patent/CO4970726A1/es unknown
- 1998-08-27 AR ARP980104289A patent/AR017514A1/es unknown
- 1998-08-27 UY UY25159A patent/UY25159A1/es not_active Application Discontinuation
- 1998-08-28 HR HR60/057,555A patent/HRP980475A2/hr not_active Application Discontinuation
- 1998-08-28 ZA ZA9807843A patent/ZA987843B/xx unknown
-
2000
- 2000-01-09 IL IL133957A patent/IL133957A/en unknown
- 2000-01-13 BG BG104076A patent/BG104076A/bg unknown
- 2000-01-14 IS IS5345A patent/IS5345A/is unknown
- 2000-02-18 OA OA1200000038A patent/OA11289A/en unknown
- 2000-02-28 NO NO20000999A patent/NO20000999L/no not_active Application Discontinuation
-
2001
- 2001-01-12 HK HK01100323A patent/HK1029530A1/xx not_active IP Right Cessation
- 2001-10-10 US US09/975,765 patent/US20020025981A1/en not_active Abandoned
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