BG103553A - Бензопиранопиролови и бензопиранопиридинови алфа-1 адренергични съединения - Google Patents

Бензопиранопиролови и бензопиранопиридинови алфа-1 адренергични съединения

Info

Publication number
BG103553A
BG103553A BG103553A BG10355399A BG103553A BG 103553 A BG103553 A BG 103553A BG 103553 A BG103553 A BG 103553A BG 10355399 A BG10355399 A BG 10355399A BG 103553 A BG103553 A BG 103553A
Authority
BG
Bulgaria
Prior art keywords
alpha
benzopyranopyrol
benzopyranopyridine
adrenergic compounds
adrenergic
Prior art date
Application number
BG103553A
Other languages
English (en)
Other versions
BG63975B1 (bg
Inventor
Michael Meyer
Robert Altenbach
Fatima Basha
William Carroll
Irene Drizin
James KERWIN
Michael Wendt
Anthony HAIGHT
Weijiang Zhang
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/980,130 external-priority patent/US6046207A/en
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of BG103553A publication Critical patent/BG103553A/bg
Publication of BG63975B1 publication Critical patent/BG63975B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrane Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Изобретението се отнася до -1 адренергични антагонисти, до -1 антагонистични състави и до метод заантагонизиране на -1 адренорецептори, приложими за лечение на доброкачествена хиперплазия на простатата (ВРН). Съединението и неговите фармацевтичноприемливи соли имат обща формула@@в която W означава бициклична хетероциклична пръстенна система.
BG103553A 1996-12-06 1999-07-05 Бензопиранопиролови и бензопиранопиридинови алфа-1 адренергични съединения BG63975B1 (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US76142396A 1996-12-06 1996-12-06
US08/980,130 US6046207A (en) 1996-12-06 1997-11-26 Benzopyranopyrrole and benzopyranopyridine α-1 adrenergic compounds
PCT/US1997/022279 WO1998024791A1 (en) 1996-12-06 1997-12-04 Benzopyranopyrrole and benzopyranopyridine alpha-1 adrenergic compounds

Publications (2)

Publication Number Publication Date
BG103553A true BG103553A (bg) 2000-06-30
BG63975B1 BG63975B1 (bg) 2003-08-29

Family

ID=27116981

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103553A BG63975B1 (bg) 1996-12-06 1999-07-05 Бензопиранопиролови и бензопиранопиридинови алфа-1 адренергични съединения

Country Status (19)

Country Link
EP (1) EP0942911B1 (bg)
JP (1) JP2002504088A (bg)
KR (1) KR20000057418A (bg)
CN (1) CN1130365C (bg)
AT (1) ATE207071T1 (bg)
AU (1) AU735764B2 (bg)
BG (1) BG63975B1 (bg)
CA (1) CA2272330A1 (bg)
CY (1) CY2260B1 (bg)
CZ (1) CZ194499A3 (bg)
DE (1) DE69707497T2 (bg)
DK (1) DK0942911T3 (bg)
ES (1) ES2168682T3 (bg)
NO (1) NO992661L (bg)
NZ (1) NZ335711A (bg)
PT (1) PT942911E (bg)
SK (1) SK283580B6 (bg)
TR (1) TR199901883T2 (bg)
WO (1) WO1998024791A1 (bg)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001519423A (ja) * 1997-10-10 2001-10-23 アボット・ラボラトリーズ 置換ピラジン化合物の調製方法
TW536402B (en) 1998-06-26 2003-06-11 Yamanouchi Pharma Co Ltd Pharmaceutical composition for the therapy of voiding dysfunction
UA69420C2 (uk) * 1998-10-06 2004-09-15 Янссен Фармацевтика Н.В. ТРИЦИКЛІЧНІ <font face="Symbol">D3</font>-ПІПЕРИДИНИ ЯК <font face="Symbol">a<sub></font>2</sub>-АНТАГОНІСТИ
SK285386B6 (sk) * 1998-10-06 2006-12-07 Janssen Pharmaceutica N. V. Tricyklické delta3-piperidíny ako farmaceutiká a spôsob ich prípravy
US6172260B1 (en) 1998-12-31 2001-01-09 Eastman Kodak Company Preparation of high dye-yield couplers and intermediates useful therein
TWI274750B (en) 1999-01-12 2007-03-01 Abbott Gmbh & Co Kg Triazole compounds showing high affinity to dopamine D3 receptor and pharmaceutical composition comprising the same
JP2001288115A (ja) * 2001-02-07 2001-10-16 Yamanouchi Pharmaceut Co Ltd 下部尿路症治療剤
US20060128719A1 (en) * 2004-12-13 2006-06-15 Boehringer Ingelheim Pharmaceuticals, Inc. Use of alpha-adrenergic blockers for the treatment of dysmenorrhea
EP3866750A4 (en) * 2018-10-17 2022-07-27 Austin Research Labs Corp. SUSPENSION FORMULATIONS OF HIGH LOAD DISPERSIONS
CN110759878B (zh) * 2019-10-29 2021-04-09 西安瑞联新材料股份有限公司 一种苯基四氢呋喃醚类化合物的合成方法
WO2023248964A1 (ja) * 2022-06-21 2023-12-28 クミアイ化学工業株式会社 ハロ酢酸を用いたスルホン誘導体の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888946A (en) * 1971-03-17 1975-06-10 Little Inc A Pyrano benzopyrans
US4117140A (en) * 1975-02-10 1978-09-26 Brown Richard E Bronchodilating piperidinoethyl benzopyranopyridinones
AU560459B2 (en) * 1982-06-01 1987-04-09 Abbott Laboratories Tetrahydro-benzo(e) isoindolines
FR2687146B1 (fr) * 1992-02-12 1994-04-01 Adir Cie Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
TR199901883T2 (xx) 1999-12-21
AU5516998A (en) 1998-06-29
NO992661D0 (no) 1999-06-02
KR20000057418A (ko) 2000-09-15
CZ194499A3 (cs) 1999-11-17
DE69707497D1 (de) 2001-11-22
CY2260B1 (en) 2003-07-04
SK71799A3 (en) 2000-01-18
PT942911E (pt) 2002-04-29
AU735764B2 (en) 2001-07-12
SK283580B6 (sk) 2003-09-11
ATE207071T1 (de) 2001-11-15
WO1998024791A1 (en) 1998-06-11
CN1246861A (zh) 2000-03-08
BG63975B1 (bg) 2003-08-29
DK0942911T3 (da) 2002-12-02
CN1130365C (zh) 2003-12-10
JP2002504088A (ja) 2002-02-05
DE69707497T2 (de) 2002-07-11
CA2272330A1 (en) 1998-06-11
EP0942911A1 (en) 1999-09-22
ES2168682T3 (es) 2002-06-16
NZ335711A (en) 2000-10-27
NO992661L (no) 1999-07-30
EP0942911B1 (en) 2001-10-17

Similar Documents

Publication Publication Date Title
ZA981080B (en) Bicyclic inhibitors of protein farnesyl transferase
ES2149451T3 (es) Antagonistas alfa-1-adrenergicos de hexahidrobenz(e)isoindol triciclico sustituido.
BG106340A (bg) Заместени оксоазахетероциклени съединения
GR3036560T3 (en) Bicyclic substituted hexahydrobenz(e)isoindole alpha-1- adrenergic antagonists
GR3035774T3 (en) Substituted benzolactam compounds as substance p antagonists
BG102998A (bg) Спиро-пиперидинови производни и приложението им като терапевтични средства
MD1632F2 (en) Bicyclic compounds, method of inhibiting the tyrosine kinases receptors as epidermal growth factor, pharmaceutical composition, methods of preventing blastocyte implantation and treatment of mammals
MD1616F2 (en) Tricyclic compounds and method of inhibiting the tyrasin kinases receptors of the epidermal growth factor, pharmaceutical composition, methods of preventing the blastocites implantation and mammals treatment
ZA955466B (en) Stereochemical wortmannin derivatives
MY132671A (en) Substituted 6,6-hetero-bicyclic derivatives
MX9805253A (es) Antagonistas del receptor de vitronectina.
MX9700883A (es) Derivados sustituidos de la quinazolina.
CA2335012A1 (en) Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
BG103553A (bg) Бензопиранопиролови и бензопиранопиридинови алфа-1 адренергични съединения
BG104719A (bg) Глюкокортикоид - селективни противовъзпалителни средства
EP0646007A1 (en) NEW DELTA-17 AND DELTA-20 UNSATURATED AND SATURATED 17 - g (b) -SUBSTITUTED-4-AZA-5-g (a) -ANDROSTAN-3-ON COMPOUNDS AS INHIBITORS OF 5-ALPHA REDUCTASE.
KR20000005379A (en) Isatin derivatives as acetylcholinesterase inhibitors and analgesics
MX9806171A (es) Derivados 2,3-benzodiazepina y sus usos como inhibidores del receptor-ampa.
AP2001002149A0 (en) Indole derivatives(Priority title)
PL329190A1 (en) Antagonists of alpha -adrenergic receptor
AU1160700A (en) Ppar gamma ligands
EA200100182A1 (ru) Лечение состояний тревожности
TR199900016T2 (xx) Benzo $g] kuinolin t�revleri.
BR9713682A (pt) Compostos alfa - 1 adrenergicos de benzopiranopirrol e benzopiranopiridina
BG102318A (bg) Епокси-азетидинони,получаването им и тяхното използване