BG103328A - Method for the preparation of n-[2-(dimethylamino)ethyl]-acridine-4-carboxamide - Google Patents

Method for the preparation of n-[2-(dimethylamino)ethyl]-acridine-4-carboxamide

Info

Publication number
BG103328A
BG103328A BG103328A BG10332899A BG103328A BG 103328 A BG103328 A BG 103328A BG 103328 A BG103328 A BG 103328A BG 10332899 A BG10332899 A BG 10332899A BG 103328 A BG103328 A BG 103328A
Authority
BG
Bulgaria
Prior art keywords
formula
compound
alkyl
accordance
produced
Prior art date
Application number
BG103328A
Other languages
Bulgarian (bg)
English (en)
Inventor
William Denny
Swarnalatha Gamage
Julie SPICER
Michael Wright
David HAYMAN
Original Assignee
Xenova Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9621795.5A external-priority patent/GB9621795D0/en
Priority claimed from GBGB9626457.7A external-priority patent/GB9626457D0/en
Application filed by Xenova Limited filed Critical Xenova Limited
Publication of BG103328A publication Critical patent/BG103328A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Wire Bonding (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
BG103328A 1996-10-18 1999-04-13 Method for the preparation of n-[2-(dimethylamino)ethyl]-acridine-4-carboxamide BG103328A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9621795.5A GB9621795D0 (en) 1996-10-18 1996-10-18 Pharmaceutical compounds
GBGB9626457.7A GB9626457D0 (en) 1996-12-20 1996-12-20 Process
PCT/GB1997/002884 WO1998017649A1 (en) 1996-10-18 1997-10-17 Process for the preparation of n-[2-(dimethylamino)ethyl]acridine-4-carboxamide

Publications (1)

Publication Number Publication Date
BG103328A true BG103328A (en) 2000-07-31

Family

ID=26310257

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103328A BG103328A (en) 1996-10-18 1999-04-13 Method for the preparation of n-[2-(dimethylamino)ethyl]-acridine-4-carboxamide

Country Status (21)

Country Link
US (1) US6111109A (id)
EP (1) EP0934277B1 (id)
JP (1) JP2001502682A (id)
KR (1) KR20000049239A (id)
AT (1) ATE232202T1 (id)
AU (1) AU741305B2 (id)
BG (1) BG103328A (id)
BR (1) BR9711945A (id)
CA (1) CA2268413A1 (id)
CZ (1) CZ135199A3 (id)
DE (1) DE69718925D1 (id)
GB (1) GB2333293B (id)
HK (1) HK1018456A1 (id)
ID (1) ID21677A (id)
NO (1) NO313382B1 (id)
NZ (1) NZ334951A (id)
PL (1) PL332728A1 (id)
RU (1) RU2178785C2 (id)
SK (1) SK50599A3 (id)
TW (1) TW430658B (id)
WO (1) WO1998017649A1 (id)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070299093A1 (en) * 2005-01-27 2007-12-27 Alma Mater Studiorum-Universitá Di Bologna Organic Compounds Useful for the Treatment of Alzheimer's Disease, Their Use and Method of Preparation
EA200701584A1 (ru) * 2005-01-27 2008-02-28 Альма Матер Студиорум - Университа' Ди Болонья Органические соединения, применяемые для лечения болезни альцгеймера, их применение и способ получения
FR2904317A1 (fr) 2006-07-27 2008-02-01 Inst Nat Sante Rech Med Analogues d'halogenobenzamides marques a titre de radiopharmaceutiques
EP2085390A1 (en) 2008-01-31 2009-08-05 Institut National De La Sante Et De La Recherche Medicale (Inserm) Labelled analogues of halobenzamides as multimodal radiopharmaceuticals and their precursors
CN105315205B (zh) * 2015-01-19 2018-03-23 威海惠安康生物科技有限公司 一种以邻硝基苯甲醛和环己醇为原料制备吖啶的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3686180A (en) * 1970-11-04 1972-08-22 Smith Kline French Lab Substituted 9-lower alkylacridine-4-carboxylic acids
NZ201084A (en) * 1982-06-25 1985-10-11 New Zealand Dev Finance 4-carboxamidoacridine derivatives and pharmaceutical compositions containing such

Also Published As

Publication number Publication date
AU741305B2 (en) 2001-11-29
CZ135199A3 (cs) 1999-09-15
US6111109A (en) 2000-08-29
KR20000049239A (ko) 2000-07-25
CA2268413A1 (en) 1998-04-30
ATE232202T1 (de) 2003-02-15
HK1018456A1 (en) 1999-12-24
WO1998017649A1 (en) 1998-04-30
PL332728A1 (en) 1999-10-11
SK50599A3 (en) 2000-05-16
EP0934277A1 (en) 1999-08-11
NO991835D0 (no) 1999-04-16
DE69718925D1 (de) 2003-03-13
EP0934277B1 (en) 2003-02-05
NO313382B1 (no) 2002-09-23
GB2333293B (en) 2000-07-12
ID21677A (id) 1999-07-08
RU2178785C2 (ru) 2002-01-27
NZ334951A (en) 2000-12-22
JP2001502682A (ja) 2001-02-27
NO991835L (no) 1999-06-16
AU4713697A (en) 1998-05-15
TW430658B (en) 2001-04-21
GB9908188D0 (en) 1999-06-02
BR9711945A (pt) 1999-08-24
GB2333293A (en) 1999-07-21

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