JPS5791991A - Preparation of 2-azetidinone derivative - Google Patents

Preparation of 2-azetidinone derivative

Info

Publication number
JPS5791991A
JPS5791991A JP16695780A JP16695780A JPS5791991A JP S5791991 A JPS5791991 A JP S5791991A JP 16695780 A JP16695780 A JP 16695780A JP 16695780 A JP16695780 A JP 16695780A JP S5791991 A JPS5791991 A JP S5791991A
Authority
JP
Japan
Prior art keywords
compound
compound expressed
formulai
catalyst
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP16695780A
Other languages
Japanese (ja)
Other versions
JPS6318956B2 (en
Inventor
Tadashi Hirata
Akira Sato
Yasuyuki Ono
Takehiro Ogasa
Kenichi Mochida
Shigeru Kobayashi
Kentaro Tamaoki
Shigeo Yoshiie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP16695780A priority Critical patent/JPS5791991A/en
Priority to ES507542A priority patent/ES8207188A1/en
Publication of JPS5791991A publication Critical patent/JPS5791991A/en
Publication of JPS6318956B2 publication Critical patent/JPS6318956B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PURPOSE: To obtain the titled compound useful as a synthetic intermediate for an antibiotic, in high yield without forming trans derivatives as a by-product, by reducing a 2-azetidinone derivative substituted by a substituent group having a double bond at the 4-position by the catalytic hydrogenation.
CONSTITUTION: The double bond (-CH=CH-) of a compound expressed by formulaI[phtN is phthalimide; Y is O or group of formula II (R3 is lower alkyl); R1 is carboxyl group, etc.; R2 is lower alkyl or phenyl]is reduced by the catalytic hydrogenation in a solvent, e.g. methanol, acetone or ethyl acetate, in the presence of Raney nickel or palladium-carbon as a catalyst at 0W100°C to give the aimed compound. The amount of the catalyst is 10W30%w/w based on the weight of the compound expressed by formulaI, and the concentration of the compound expressed by formulaIis 0.01M/lW1M/l.
COPYRIGHT: (C)1982,JPO&Japio
JP16695780A 1980-11-27 1980-11-27 Preparation of 2-azetidinone derivative Granted JPS5791991A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP16695780A JPS5791991A (en) 1980-11-27 1980-11-27 Preparation of 2-azetidinone derivative
ES507542A ES8207188A1 (en) 1980-11-27 1981-11-27 Preparation of 2-azetidinone derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16695780A JPS5791991A (en) 1980-11-27 1980-11-27 Preparation of 2-azetidinone derivative

Publications (2)

Publication Number Publication Date
JPS5791991A true JPS5791991A (en) 1982-06-08
JPS6318956B2 JPS6318956B2 (en) 1988-04-20

Family

ID=15840748

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16695780A Granted JPS5791991A (en) 1980-11-27 1980-11-27 Preparation of 2-azetidinone derivative

Country Status (2)

Country Link
JP (1) JPS5791991A (en)
ES (1) ES8207188A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05192282A (en) * 1992-01-20 1993-08-03 Tokyo Electric Co Ltd Vacuum cleaner

Also Published As

Publication number Publication date
JPS6318956B2 (en) 1988-04-20
ES507542A0 (en) 1982-09-01
ES8207188A1 (en) 1982-09-01

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