JPS5791991A - Preparation of 2-azetidinone derivative - Google Patents
Preparation of 2-azetidinone derivativeInfo
- Publication number
- JPS5791991A JPS5791991A JP16695780A JP16695780A JPS5791991A JP S5791991 A JPS5791991 A JP S5791991A JP 16695780 A JP16695780 A JP 16695780A JP 16695780 A JP16695780 A JP 16695780A JP S5791991 A JPS5791991 A JP S5791991A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- compound expressed
- formulai
- catalyst
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PURPOSE: To obtain the titled compound useful as a synthetic intermediate for an antibiotic, in high yield without forming trans derivatives as a by-product, by reducing a 2-azetidinone derivative substituted by a substituent group having a double bond at the 4-position by the catalytic hydrogenation.
CONSTITUTION: The double bond (-CH=CH-) of a compound expressed by formulaI[phtN is phthalimide; Y is O or group of formula II (R3 is lower alkyl); R1 is carboxyl group, etc.; R2 is lower alkyl or phenyl]is reduced by the catalytic hydrogenation in a solvent, e.g. methanol, acetone or ethyl acetate, in the presence of Raney nickel or palladium-carbon as a catalyst at 0W100°C to give the aimed compound. The amount of the catalyst is 10W30%w/w based on the weight of the compound expressed by formulaI, and the concentration of the compound expressed by formulaIis 0.01M/lW1M/l.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16695780A JPS5791991A (en) | 1980-11-27 | 1980-11-27 | Preparation of 2-azetidinone derivative |
ES507542A ES8207188A1 (en) | 1980-11-27 | 1981-11-27 | Preparation of 2-azetidinone derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16695780A JPS5791991A (en) | 1980-11-27 | 1980-11-27 | Preparation of 2-azetidinone derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5791991A true JPS5791991A (en) | 1982-06-08 |
JPS6318956B2 JPS6318956B2 (en) | 1988-04-20 |
Family
ID=15840748
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP16695780A Granted JPS5791991A (en) | 1980-11-27 | 1980-11-27 | Preparation of 2-azetidinone derivative |
Country Status (2)
Country | Link |
---|---|
JP (1) | JPS5791991A (en) |
ES (1) | ES8207188A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05192282A (en) * | 1992-01-20 | 1993-08-03 | Tokyo Electric Co Ltd | Vacuum cleaner |
-
1980
- 1980-11-27 JP JP16695780A patent/JPS5791991A/en active Granted
-
1981
- 1981-11-27 ES ES507542A patent/ES8207188A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS6318956B2 (en) | 1988-04-20 |
ES507542A0 (en) | 1982-09-01 |
ES8207188A1 (en) | 1982-09-01 |
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