JPS5795932A - Preparation of hydroquinone derivative - Google Patents

Preparation of hydroquinone derivative

Info

Publication number
JPS5795932A
JPS5795932A JP55172272A JP17227280A JPS5795932A JP S5795932 A JPS5795932 A JP S5795932A JP 55172272 A JP55172272 A JP 55172272A JP 17227280 A JP17227280 A JP 17227280A JP S5795932 A JPS5795932 A JP S5795932A
Authority
JP
Japan
Prior art keywords
hydroquinone derivative
formula
preparation
geranyl
dimethoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP55172272A
Other languages
Japanese (ja)
Inventor
Yasuo Butsugan
Tatsuro Hamanaka
Naoki Araki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kuraray Co Ltd
Original Assignee
Kuraray Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kuraray Co Ltd filed Critical Kuraray Co Ltd
Priority to JP55172272A priority Critical patent/JPS5795932A/en
Publication of JPS5795932A publication Critical patent/JPS5795932A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To prepare the titled compound useful as an intermediate for the preparation of vitamin K1, K2, coenzyme Q, etc., in high selectivity, suppressing the side reactions effectively, by reacting a phosphoric acid ester with a hydroquinone derivative in the presence of a Lewis acid keeping the reaction temperature at a low level.
CONSTITUTION: A hydroquinone derivative of formula IV (e.g. 1,4-dimethoxy-2- geranyl-3-methyl-naphthalene) is prepared by reacting a phosphoric acid ester of formulaI[n is 0W9; Ar is (substituted) phenyl; the dotted line is single or double bond], e.g. geranyl disphenyl phosphate, with a hydroquinone derivative of formula II (R1 is protecting group; R2 is methyl, methoxy, or two R2s may together form the group of formula III)(e.g. 1,4-dimethoxy-2-methylnaphthalene) in the presence of a Lewis acid at about -80W0°C, pref. about -80W-30°C.
COPYRIGHT: (C)1982,JPO&Japio
JP55172272A 1980-12-05 1980-12-05 Preparation of hydroquinone derivative Pending JPS5795932A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP55172272A JPS5795932A (en) 1980-12-05 1980-12-05 Preparation of hydroquinone derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55172272A JPS5795932A (en) 1980-12-05 1980-12-05 Preparation of hydroquinone derivative

Publications (1)

Publication Number Publication Date
JPS5795932A true JPS5795932A (en) 1982-06-15

Family

ID=15938827

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55172272A Pending JPS5795932A (en) 1980-12-05 1980-12-05 Preparation of hydroquinone derivative

Country Status (1)

Country Link
JP (1) JPS5795932A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3018116B1 (en) 2008-09-24 2020-10-28 Kappa Bioscience As Vitamin k2 intermediates

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3018116B1 (en) 2008-09-24 2020-10-28 Kappa Bioscience As Vitamin k2 intermediates

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