JPS5795932A - Preparation of hydroquinone derivative - Google Patents

Preparation of hydroquinone derivative

Info

Publication number
JPS5795932A
JPS5795932A JP55172272A JP17227280A JPS5795932A JP S5795932 A JPS5795932 A JP S5795932A JP 55172272 A JP55172272 A JP 55172272A JP 17227280 A JP17227280 A JP 17227280A JP S5795932 A JPS5795932 A JP S5795932A
Authority
JP
Japan
Prior art keywords
hydroquinone derivative
formula
preparation
geranyl
dimethoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP55172272A
Other languages
Japanese (ja)
Inventor
Yasuo Butsugan
Tatsuro Hamanaka
Naoki Araki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kuraray Co Ltd
Original Assignee
Kuraray Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kuraray Co Ltd filed Critical Kuraray Co Ltd
Priority to JP55172272A priority Critical patent/JPS5795932A/en
Publication of JPS5795932A publication Critical patent/JPS5795932A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To prepare the titled compound useful as an intermediate for the preparation of vitamin K1, K2, coenzyme Q, etc., in high selectivity, suppressing the side reactions effectively, by reacting a phosphoric acid ester with a hydroquinone derivative in the presence of a Lewis acid keeping the reaction temperature at a low level.
CONSTITUTION: A hydroquinone derivative of formula IV (e.g. 1,4-dimethoxy-2- geranyl-3-methyl-naphthalene) is prepared by reacting a phosphoric acid ester of formulaI[n is 0W9; Ar is (substituted) phenyl; the dotted line is single or double bond], e.g. geranyl disphenyl phosphate, with a hydroquinone derivative of formula II (R1 is protecting group; R2 is methyl, methoxy, or two R2s may together form the group of formula III)(e.g. 1,4-dimethoxy-2-methylnaphthalene) in the presence of a Lewis acid at about -80W0°C, pref. about -80W-30°C.
COPYRIGHT: (C)1982,JPO&Japio
JP55172272A 1980-12-05 1980-12-05 Preparation of hydroquinone derivative Pending JPS5795932A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP55172272A JPS5795932A (en) 1980-12-05 1980-12-05 Preparation of hydroquinone derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55172272A JPS5795932A (en) 1980-12-05 1980-12-05 Preparation of hydroquinone derivative

Publications (1)

Publication Number Publication Date
JPS5795932A true JPS5795932A (en) 1982-06-15

Family

ID=15938827

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55172272A Pending JPS5795932A (en) 1980-12-05 1980-12-05 Preparation of hydroquinone derivative

Country Status (1)

Country Link
JP (1) JPS5795932A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3018116B1 (en) 2008-09-24 2020-10-28 Kappa Bioscience As Vitamin k2 intermediates

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3018116B1 (en) 2008-09-24 2020-10-28 Kappa Bioscience As Vitamin k2 intermediates

Similar Documents

Publication Publication Date Title
JPS5795932A (en) Preparation of hydroquinone derivative
JPS5452043A (en) Preparation of peroxide
JPS5767530A (en) Preparation of hydroquinone derivative
JPS57126427A (en) Preparation of 1-substituted-azulene derivative
JPS5699480A (en) Preparation of pyridopyrimidine derivative
JPS53130623A (en) Preparation of n-hydroxyalkyl-substituted phosphoroamidate
JPS57144253A (en) Preparation of crude aminoalkylthiol
JPS57140789A (en) Preparation of l-ascorbyl phosphate
JPS5677266A (en) Synthesis of 2,3-dioxopiperazine derivative
JPS55153777A (en) Improved method of preparation of 3-methyl-3-(substituted phenyl)-glycidic ester
JPS5436249A (en) 24-oxocholest-5-en-3beta2-ol dand preparation of its esters
JPS56169686A (en) Preparation of vitamine e homolog and its analoqous compound
JPS572257A (en) Preparation of 4-hydroxybenzylnitrile derivative
JPS5770847A (en) Preparation of 3-aminoglutaric acid dialkyl ester
JPS5758890A (en) Preparation of glucosylmoranoline derivative
JPS57200331A (en) Preparation of dicyclopentenyloxyalkyl carboxylate
JPS5742679A (en) Preparation of phenylpiperazine derivative
JPS55102581A (en) Preparation of 4-piperidone spiroketal compound
JPS56147787A (en) Preparation of theobromine derivative
JPS55120591A (en) Phosphinoethylmalonic acid derivative, and preparation thereof
JPS5436226A (en) Preparation of derivative of phenyl acetic acid
JPS5731954A (en) Preparation of quinophthalone dye
JPS5589284A (en) Preparation of xanthine derivative
JPS5527113A (en) Preparation of dihydrocoenzyme q compound
JPS55120590A (en) Preparation of gamma-amino-gamma-carboxypropyl-methylphosphinic acid