JPS56100786A - 1-azaerythrinan derivative - Google Patents
1-azaerythrinan derivativeInfo
- Publication number
- JPS56100786A JPS56100786A JP416080A JP416080A JPS56100786A JP S56100786 A JPS56100786 A JP S56100786A JP 416080 A JP416080 A JP 416080A JP 416080 A JP416080 A JP 416080A JP S56100786 A JPS56100786 A JP S56100786A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- azaerythrinan
- give
- iii
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:1-Azaerythrinan derivatives of formula I (Y is -CH2-, -OCH2-; R1, R2, R3 are H, lower alkoxy; R4 is lower alkyl) and their acid adducts. EXAMPLE:16,17-Dimethoxy-1-methyl-1-azaerythrinan. USE:Analgesic: they have an activity of depressing the central nervous system. PREPARATION:A compound of formula II (R5 is lower alkyl) or formula III is reduced with a metal hydride to give the compound of formula I. The compound of formula II is obtained by the thermal condensation between a compound of formula IV (R6 is alkyl) and another compound of formula V followed by heating under acidic conditions. At the same time, a compound of formula VI also is obtained, which is alkylated at the 1 position to give the compound of formula III. The reduction of a compound of formula II or III is effected, e.g., using LiA1H4 in an inert organic solvent to give the titled compound in high yield.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55004160A JPS6019911B2 (en) | 1980-01-17 | 1980-01-17 | 1-Azaerythrinane derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55004160A JPS6019911B2 (en) | 1980-01-17 | 1980-01-17 | 1-Azaerythrinane derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56100786A true JPS56100786A (en) | 1981-08-12 |
JPS6019911B2 JPS6019911B2 (en) | 1985-05-18 |
Family
ID=11576982
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55004160A Expired JPS6019911B2 (en) | 1980-01-17 | 1980-01-17 | 1-Azaerythrinane derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6019911B2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4997832A (en) * | 1988-04-20 | 1991-03-05 | Ciba-Geigy Corporation | Heterotetracyclic lactam derivatives |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10362273B2 (en) | 2011-08-05 | 2019-07-23 | Honeywell International Inc. | Systems and methods for managing video data |
US10523903B2 (en) | 2013-10-30 | 2019-12-31 | Honeywell International Inc. | Computer implemented systems frameworks and methods configured for enabling review of incident data |
-
1980
- 1980-01-17 JP JP55004160A patent/JPS6019911B2/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4997832A (en) * | 1988-04-20 | 1991-03-05 | Ciba-Geigy Corporation | Heterotetracyclic lactam derivatives |
Also Published As
Publication number | Publication date |
---|---|
JPS6019911B2 (en) | 1985-05-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL99571A (en) | Process for the preparation of water soluble 10-hydroxy-9-(substituted methyl)camptothecin analogs | |
GB1148717A (en) | Phenylbenz (f)-2,5-oxazocine derivatives and homologues and pharmaceutical compositions | |
UA8018A1 (en) | Process for the preparation of 1-cyclopropyl-7-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid | |
JPS56100786A (en) | 1-azaerythrinan derivative | |
JPS5259174A (en) | Preparation of n-substituted uracil compounds | |
FR2479213B1 (en) | ||
JPS5728046A (en) | Preparation of 4-substituted indole | |
JPS57167902A (en) | Herbicidal composition | |
JPS5432480A (en) | Novel preparation of piperidine derivatives | |
JPS5640643A (en) | Preparation of ethyl trans-2-decen-4-ynoate | |
JPS56156263A (en) | Carbostyril derivative | |
JPS5436274A (en) | Preparation of propiophenone derivative | |
ES8705454A1 (en) | Imidazoalkylcarboxylic-acid derivatives, process for their preparation and their use in the preparation of pharmaceutically active compounds. | |
JPS5527158A (en) | 5-oxo-3,4,5,6,7,8-hexahydrocarbostyril derivative | |
JPS5536456A (en) | 1,2-benzodiazepine derivative and its preparation | |
JPS5432476A (en) | Preparation of 3-aminopyridines | |
JPS55143963A (en) | Novel nitro compound and its preparation | |
JPS53130619A (en) | Preparation of high purity isoprenylacetic acid | |
JPS5337650A (en) | Preparation of 1,5-diphenoxyanthraquinone | |
JPS5268167A (en) | Preparation of 88exoohydroxymethyllendootricyclo 5*2*1*0 decade | |
JPS549225A (en) | Preparation of hydrazinoalkanesulfonic acid derivatives | |
JPS53132530A (en) | Preparation of p-iodoaniline | |
JPS53108976A (en) | Preparation of 8-chloroquinaldine | |
JPS5536455A (en) | Indazole derivative and its preparation | |
JPS5231059A (en) | Preparation of oxybenzoylbenzoic acids |