HK1018456A1 - Process for the preparation of n-[2-(dimethylamino)ethyl]acridine-4-carboxamide used as anti cancer compounds - Google Patents
Process for the preparation of n-[2-(dimethylamino)ethyl]acridine-4-carboxamide used as anti cancer compoundsInfo
- Publication number
- HK1018456A1 HK1018456A1 HK99103542A HK99103542A HK1018456A1 HK 1018456 A1 HK1018456 A1 HK 1018456A1 HK 99103542 A HK99103542 A HK 99103542A HK 99103542 A HK99103542 A HK 99103542A HK 1018456 A1 HK1018456 A1 HK 1018456A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- acridine
- dimethylamino
- ethyl
- preparation
- pct
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Glass Compositions (AREA)
- Iron Core Of Rotating Electric Machines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyridine Compounds (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Plural Heterocyclic Compounds (AREA)
- Wire Bonding (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9621795.5A GB9621795D0 (en) | 1996-10-18 | 1996-10-18 | Pharmaceutical compounds |
GBGB9626457.7A GB9626457D0 (en) | 1996-12-20 | 1996-12-20 | Process |
PCT/GB1997/002884 WO1998017649A1 (en) | 1996-10-18 | 1997-10-17 | Process for the preparation of n-[2-(dimethylamino)ethyl]acridine-4-carboxamide |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1018456A1 true HK1018456A1 (en) | 1999-12-24 |
Family
ID=26310257
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK99103542A HK1018456A1 (en) | 1996-10-18 | 1999-08-14 | Process for the preparation of n-[2-(dimethylamino)ethyl]acridine-4-carboxamide used as anti cancer compounds |
Country Status (21)
Country | Link |
---|---|
US (1) | US6111109A (id) |
EP (1) | EP0934277B1 (id) |
JP (1) | JP2001502682A (id) |
KR (1) | KR20000049239A (id) |
AT (1) | ATE232202T1 (id) |
AU (1) | AU741305B2 (id) |
BG (1) | BG103328A (id) |
BR (1) | BR9711945A (id) |
CA (1) | CA2268413A1 (id) |
CZ (1) | CZ135199A3 (id) |
DE (1) | DE69718925D1 (id) |
GB (1) | GB2333293B (id) |
HK (1) | HK1018456A1 (id) |
ID (1) | ID21677A (id) |
NO (1) | NO313382B1 (id) |
NZ (1) | NZ334951A (id) |
PL (1) | PL332728A1 (id) |
RU (1) | RU2178785C2 (id) |
SK (1) | SK50599A3 (id) |
TW (1) | TW430658B (id) |
WO (1) | WO1998017649A1 (id) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070299093A1 (en) * | 2005-01-27 | 2007-12-27 | Alma Mater Studiorum-Universitá Di Bologna | Organic Compounds Useful for the Treatment of Alzheimer's Disease, Their Use and Method of Preparation |
WO2006080043A2 (en) * | 2005-01-27 | 2006-08-03 | Alma Mater Studiorum- Universita' Di Bologna | Organic compounds useful for the treatment of alzheimer's disease, their use and method of preparation |
FR2904317A1 (fr) | 2006-07-27 | 2008-02-01 | Inst Nat Sante Rech Med | Analogues d'halogenobenzamides marques a titre de radiopharmaceutiques |
EP2085390A1 (en) | 2008-01-31 | 2009-08-05 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Labelled analogues of halobenzamides as multimodal radiopharmaceuticals and their precursors |
CN105315205B (zh) * | 2015-01-19 | 2018-03-23 | 威海惠安康生物科技有限公司 | 一种以邻硝基苯甲醛和环己醇为原料制备吖啶的方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3686180A (en) * | 1970-11-04 | 1972-08-22 | Smith Kline French Lab | Substituted 9-lower alkylacridine-4-carboxylic acids |
NZ201084A (en) * | 1982-06-25 | 1985-10-11 | New Zealand Dev Finance | 4-carboxamidoacridine derivatives and pharmaceutical compositions containing such |
-
1997
- 1997-10-17 DE DE69718925T patent/DE69718925D1/de not_active Expired - Lifetime
- 1997-10-17 US US09/284,570 patent/US6111109A/en not_active Expired - Fee Related
- 1997-10-17 CA CA002268413A patent/CA2268413A1/en not_active Abandoned
- 1997-10-17 JP JP10519107A patent/JP2001502682A/ja active Pending
- 1997-10-17 PL PL97332728A patent/PL332728A1/xx unknown
- 1997-10-17 AU AU47136/97A patent/AU741305B2/en not_active Ceased
- 1997-10-17 GB GB9908188A patent/GB2333293B/en not_active Expired - Fee Related
- 1997-10-17 NZ NZ334951A patent/NZ334951A/xx unknown
- 1997-10-17 RU RU99109986/04A patent/RU2178785C2/ru not_active IP Right Cessation
- 1997-10-17 ID IDW990202A patent/ID21677A/id unknown
- 1997-10-17 SK SK505-99A patent/SK50599A3/sk unknown
- 1997-10-17 WO PCT/GB1997/002884 patent/WO1998017649A1/en not_active Application Discontinuation
- 1997-10-17 KR KR1019990703343A patent/KR20000049239A/ko not_active Application Discontinuation
- 1997-10-17 TW TW086115308A patent/TW430658B/zh active
- 1997-10-17 EP EP97909455A patent/EP0934277B1/en not_active Expired - Lifetime
- 1997-10-17 CZ CZ991351A patent/CZ135199A3/cs unknown
- 1997-10-17 BR BR9711945A patent/BR9711945A/pt unknown
- 1997-10-17 AT AT97909455T patent/ATE232202T1/de not_active IP Right Cessation
-
1999
- 1999-04-13 BG BG103328A patent/BG103328A/xx unknown
- 1999-04-16 NO NO19991835A patent/NO313382B1/no not_active IP Right Cessation
- 1999-08-14 HK HK99103542A patent/HK1018456A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ID21677A (id) | 1999-07-08 |
PL332728A1 (en) | 1999-10-11 |
RU2178785C2 (ru) | 2002-01-27 |
AU741305B2 (en) | 2001-11-29 |
ATE232202T1 (de) | 2003-02-15 |
DE69718925D1 (de) | 2003-03-13 |
NO313382B1 (no) | 2002-09-23 |
EP0934277B1 (en) | 2003-02-05 |
GB9908188D0 (en) | 1999-06-02 |
US6111109A (en) | 2000-08-29 |
CA2268413A1 (en) | 1998-04-30 |
GB2333293A (en) | 1999-07-21 |
JP2001502682A (ja) | 2001-02-27 |
NO991835D0 (no) | 1999-04-16 |
KR20000049239A (ko) | 2000-07-25 |
NZ334951A (en) | 2000-12-22 |
SK50599A3 (en) | 2000-05-16 |
TW430658B (en) | 2001-04-21 |
NO991835L (no) | 1999-06-16 |
CZ135199A3 (cs) | 1999-09-15 |
WO1998017649A1 (en) | 1998-04-30 |
BR9711945A (pt) | 1999-08-24 |
GB2333293B (en) | 2000-07-12 |
BG103328A (en) | 2000-07-31 |
EP0934277A1 (en) | 1999-08-11 |
AU4713697A (en) | 1998-05-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20041017 |