BG102709A - Антиглюкокортикоидно лекарствено средство - Google Patents
Антиглюкокортикоидно лекарствено средствоInfo
- Publication number
- BG102709A BG102709A BG102709A BG10270998A BG102709A BG 102709 A BG102709 A BG 102709A BG 102709 A BG102709 A BG 102709A BG 10270998 A BG10270998 A BG 10270998A BG 102709 A BG102709 A BG 102709A
- Authority
- BG
- Bulgaria
- Prior art keywords
- antiglucocorticoid
- cells
- chains
- medicamentous
- chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
(54) АНТИГЛЮКОКОРТИКОИДНО ЛЕКАРСТВЕНО СРЕДСТВО@(57) Средството намира приложение в хуманната и ветеринарна медицина. То представлява антиглю-кокортикоиден лекарствен препарат с нестероидна природа, сниска токсичност и висока ефикасност за регулиранечувствителността на клетките на мле-копитаещите към действието на глюкокортикоид-ните хормони. С цел селективно подтискане действието на глюкокортикоидните хормони върху клетвите на млекопитаещите сеизползва феромон от насекоми с нестероидна природа или негов синтетичен аналог или производно, представляващо дъл-говерижен ненаситен алифатен алкохол, алдехид или естер. Дължината на линейната въглеродна верига на всеки от посочените елементи е в границите от 10 до 21 атома. За увеличаване на терапевтичния ефект се използват два или повече феромона и/или техните синтетични аналози и производни, подбрани съгласно принципа на съществена разлика вхидрофобността, пропорционална на дължините на алифатните въглеводородни вериги. Разликата между дължините на веригите трябва да бъде не по-малка от пет.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU96101194/14A RU2125446C1 (ru) | 1996-01-31 | 1996-01-31 | Антиглюкокортикоидное лекарственное средство |
PCT/RU1996/000028 WO1997027845A1 (fr) | 1996-01-31 | 1996-02-01 | Medicament a base d'anti-glucocorticoide |
Publications (1)
Publication Number | Publication Date |
---|---|
BG102709A true BG102709A (bg) | 1999-06-30 |
Family
ID=20175968
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG102709A Pending BG102709A (bg) | 1996-01-31 | 1998-08-20 | Антиглюкокортикоидно лекарствено средство |
Country Status (24)
Country | Link |
---|---|
US (1) | US5965623A (bg) |
EP (1) | EP0896819A4 (bg) |
JP (1) | JPH11504946A (bg) |
KR (1) | KR100347862B1 (bg) |
CN (1) | CN1213964A (bg) |
AU (1) | AU710479B2 (bg) |
BG (1) | BG102709A (bg) |
BR (1) | BR9612470A (bg) |
CA (1) | CA2244985A1 (bg) |
CZ (1) | CZ160598A3 (bg) |
EE (1) | EE9800209A (bg) |
GE (1) | GEP20001955B (bg) |
HU (1) | HUP9900504A2 (bg) |
LT (1) | LT4441B (bg) |
LV (1) | LV12177B (bg) |
MD (1) | MD1430B1 (bg) |
MX (1) | MX9806182A (bg) |
NO (1) | NO983508D0 (bg) |
PL (1) | PL187564B1 (bg) |
RU (1) | RU2125446C1 (bg) |
SI (1) | SI9620053A (bg) |
SK (1) | SK65598A3 (bg) |
UA (1) | UA48212C2 (bg) |
WO (1) | WO1997027845A1 (bg) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001039766A2 (en) * | 1999-12-01 | 2001-06-07 | Alydar Pharmaceuticals Ltd. | Screening invertebrate pheromones for therapeutic activity |
US6548706B2 (en) * | 1999-12-23 | 2003-04-15 | Aerojet Fine Chemicals Llc | Preparation of 2S,3S-N-isobutyl-N-(2-hydroxy-3-amino-4-phenylbutyl) -p-nitrobenzenesulfonylamide hydrochloride and other derivatives of 2-hydroxy-1,3-diamines |
EP1409656A4 (en) * | 2001-03-12 | 2005-01-12 | Darley Pharmaceuticals Ltd | SCREENING OF PHEROMONAL COMPOUNDS OF NON-STEROID AND NON-PEPTIDE INVERTEBRATE HAVING ACTIVITY MODULATING MITOGEN-ACTIVATED PROTEIN KINASE |
US6806293B1 (en) | 2001-03-12 | 2004-10-19 | Darley Pharmaceuticals Ltd | Use of pheromone compounds having MAP kinase modulating activity |
WO2003092614A2 (en) * | 2002-05-02 | 2003-11-13 | Hickle Randall S | Lipid removal from the body |
US6752649B2 (en) * | 2002-11-07 | 2004-06-22 | Xentris, Llc | Illuminated indicia power supply apparatus and method of manufacture |
DE10335845B4 (de) * | 2003-05-09 | 2006-08-31 | Müller, Martina, Dr.med. | Pheromone als Antikrebsmittel |
US20110195501A1 (en) * | 2008-08-06 | 2011-08-11 | Pangu Gautam D | Ultrasonically induced release from polymer vesicles |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US161926A (en) | 1875-04-13 | Improvement in ink-wells | ||
US2900756A (en) * | 1958-12-09 | 1959-08-25 | Jacobson Martin | Attractants for the gypsy moth |
EP0149847A3 (en) * | 1983-12-26 | 1989-11-08 | Eisai Co., Ltd. | Therapeutic and preventive agent containing dolichol |
JPH0759504B2 (ja) * | 1986-01-23 | 1995-06-28 | エーザイ株式会社 | ポリプレニルアルコ−ル含有注射剤 |
US5019569A (en) * | 1986-11-03 | 1991-05-28 | Ortho Pharmaceutical Corporation | Reversal of glucocorticoid-induced skin atrophy |
US4740627A (en) * | 1987-05-21 | 1988-04-26 | Phillips Petroleum Company | Synthesis of E,Z-11-tetradecen-1-al |
ATE80313T1 (de) | 1988-02-29 | 1992-09-15 | Pfizer | Mittel zur erhoehung des transdermalen penetrationsflusses. |
US5190978A (en) * | 1989-09-29 | 1993-03-02 | Dai-Ichi Kogyo Seiyaku Co. Ltd. | Carcinostatic compositions and methods |
-
1996
- 1996-01-02 UA UA98074187A patent/UA48212C2/uk unknown
- 1996-01-31 RU RU96101194/14A patent/RU2125446C1/ru not_active IP Right Cessation
- 1996-02-01 EE EE9800209A patent/EE9800209A/xx unknown
- 1996-02-01 HU HU9900504A patent/HUP9900504A2/hu unknown
- 1996-02-01 GE GEAP19964288A patent/GEP20001955B/en unknown
- 1996-02-01 JP JP9527525A patent/JPH11504946A/ja active Pending
- 1996-02-01 AU AU46363/96A patent/AU710479B2/en not_active Ceased
- 1996-02-01 CZ CZ981605A patent/CZ160598A3/cs unknown
- 1996-02-01 CA CA002244985A patent/CA2244985A1/en not_active Abandoned
- 1996-02-01 KR KR10-1998-0705074A patent/KR100347862B1/ko not_active IP Right Cessation
- 1996-02-01 SI SI9620053A patent/SI9620053A/sl not_active IP Right Cessation
- 1996-02-01 WO PCT/RU1996/000028 patent/WO1997027845A1/ru not_active Application Discontinuation
- 1996-02-01 BR BR9612470A patent/BR9612470A/pt not_active Application Discontinuation
- 1996-02-01 EP EP96902026A patent/EP0896819A4/en not_active Withdrawn
- 1996-02-01 CN CN96180161A patent/CN1213964A/zh active Pending
- 1996-02-01 MD MD98-0171A patent/MD1430B1/ro unknown
- 1996-02-01 US US08/930,733 patent/US5965623A/en not_active Expired - Fee Related
- 1996-02-01 SK SK655-98A patent/SK65598A3/sk unknown
- 1996-02-01 PL PL96322596A patent/PL187564B1/pl unknown
-
1998
- 1998-04-21 LT LT98-054A patent/LT4441B/lt not_active IP Right Cessation
- 1998-05-28 LV LVP-98-126A patent/LV12177B/lv unknown
- 1998-07-30 NO NO983508A patent/NO983508D0/no unknown
- 1998-07-31 MX MX9806182A patent/MX9806182A/es unknown
- 1998-08-20 BG BG102709A patent/BG102709A/bg active Pending
Also Published As
Publication number | Publication date |
---|---|
GEP20001955B (en) | 2000-03-05 |
PL322596A1 (en) | 1998-02-02 |
EP0896819A4 (en) | 2001-11-07 |
LV12177B (lv) | 1999-06-20 |
UA48212C2 (uk) | 2002-08-15 |
CN1213964A (zh) | 1999-04-14 |
LT98054A (en) | 1998-10-26 |
LV12177A (lv) | 1998-12-20 |
CA2244985A1 (en) | 1997-08-07 |
MX9806182A (es) | 1998-10-31 |
WO1997027845A1 (fr) | 1997-08-07 |
PL187564B1 (pl) | 2004-08-31 |
BR9612470A (pt) | 1999-07-13 |
CZ160598A3 (cs) | 1998-08-12 |
HUP9900504A2 (en) | 1999-09-28 |
AU710479B2 (en) | 1999-09-23 |
AU4636396A (en) | 1997-08-22 |
NO983508L (no) | 1998-07-30 |
EE9800209A (et) | 1998-12-15 |
SK65598A3 (en) | 1998-09-09 |
MD1430B1 (ro) | 2000-03-31 |
KR100347862B1 (ko) | 2003-01-24 |
JPH11504946A (ja) | 1999-05-11 |
US5965623A (en) | 1999-10-12 |
EP0896819A1 (en) | 1999-02-17 |
SI9620053A (sl) | 1998-04-30 |
KR19990076946A (ko) | 1999-10-25 |
NO983508D0 (no) | 1998-07-30 |
LT4441B (lt) | 1999-01-25 |
RU2125446C1 (ru) | 1999-01-27 |
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