BG102163A - Inhibitors of adenosinekinase modified in c-4'position - Google Patents

Inhibitors of adenosinekinase modified in c-4'position

Info

Publication number
BG102163A
BG102163A BG102163A BG10216398A BG102163A BG 102163 A BG102163 A BG 102163A BG 102163 A BG102163 A BG 102163A BG 10216398 A BG10216398 A BG 10216398A BG 102163 A BG102163 A BG 102163A
Authority
BG
Bulgaria
Prior art keywords
inhibitors
adenosinekinase
modified
diseases
relates
Prior art date
Application number
BG102163A
Other languages
Bulgarian (bg)
English (en)
Inventor
Serge Boyer
Mark Erion
Bheemarao Ugarkar
Original Assignee
Gensia Sicor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gensia Sicor filed Critical Gensia Sicor
Publication of BG102163A publication Critical patent/BG102163A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/14—Pyrrolo-pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BG102163A 1995-06-07 1998-01-07 Inhibitors of adenosinekinase modified in c-4'position BG102163A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/486,161 US5674998A (en) 1989-09-15 1995-06-07 C-4' modified adenosine kinase inhibitors
PCT/US1996/010404 WO1996040705A1 (fr) 1995-06-07 1996-06-07 Inhibiteurs de l'adenosine kinase modifies en c-4'

Publications (1)

Publication Number Publication Date
BG102163A true BG102163A (en) 1998-10-30

Family

ID=23930844

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102163A BG102163A (en) 1995-06-07 1998-01-07 Inhibitors of adenosinekinase modified in c-4'position

Country Status (24)

Country Link
US (1) US5674998A (fr)
EP (1) EP0832091B1 (fr)
JP (1) JPH11507387A (fr)
KR (1) KR19990022740A (fr)
CN (1) CN1190401A (fr)
AP (1) AP9701165A0 (fr)
AT (1) ATE257841T1 (fr)
AU (1) AU6178396A (fr)
BG (1) BG102163A (fr)
BR (1) BR9609013A (fr)
CA (1) CA2220642A1 (fr)
CZ (1) CZ392797A3 (fr)
DE (1) DE69631330T2 (fr)
EA (1) EA199800009A1 (fr)
HU (1) HUP9802193A3 (fr)
IL (1) IL122335A0 (fr)
IS (1) IS4621A (fr)
MX (1) MX9709859A (fr)
NO (1) NO975585L (fr)
OA (1) OA10639A (fr)
PL (1) PL323904A1 (fr)
SK (1) SK166097A3 (fr)
TR (1) TR199701539T1 (fr)
WO (1) WO1996040705A1 (fr)

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US6713474B2 (en) 1998-09-18 2004-03-30 Abbott Gmbh & Co. Kg Pyrrolopyrimidines as therapeutic agents
YU25500A (sh) 1999-05-11 2003-08-29 Pfizer Products Inc. Postupak za sintezu analoga nukleozida
MXPA02001753A (es) * 1999-08-27 2002-10-23 Ribapharm Inc Analogos de nucleosido de pirrolo [2,3-d]pirimidina.
US6831069B2 (en) 1999-08-27 2004-12-14 Ribapharm Inc. Pyrrolo[2,3-d]pyrimidine nucleoside analogs
US7071199B1 (en) 1999-09-17 2006-07-04 Abbott Gmbh & Cco. Kg Kinase inhibitors as therapeutic agents
CA2385747A1 (fr) 1999-09-17 2001-03-22 Gavin C. Hirst Pyrazolopyrimidines en tant qu'agents therapeutiques
AU1929801A (en) * 1999-12-16 2001-06-25 Alcon Inc. Inhibitors of adenosine kinase for the treatment of optic nerve and retinal damage
CN1372564A (zh) * 2000-02-10 2002-10-02 三井化学株式会社 选择性制备1－磷酸化糖衍生物端基异构体的方法和制备核苷的方法
US7638496B2 (en) 2000-02-15 2009-12-29 Valeant Pharmaceuticals North America Nucleoside analogs with carboxamidine modified monocyclic base
US7414036B2 (en) * 2002-01-25 2008-08-19 Muscagen Limited Compounds useful as A3 adenosine receptor agonists
AU2002951247A0 (en) * 2002-09-06 2002-09-19 Alchemia Limited Compounds that interact with kinases
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US9512125B2 (en) 2004-11-19 2016-12-06 The Regents Of The University Of California Substituted pyrazolo[3.4-D] pyrimidines as anti-inflammatory agents
JP5048520B2 (ja) 2005-02-04 2012-10-17 ミレニアム ファーマシューティカルズ， インコーポレイテッド Ｅ１活性化酵素の阻害剤
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US20080032960A1 (en) 2006-04-04 2008-02-07 Regents Of The University Of California PI3 kinase antagonists
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US8193182B2 (en) 2008-01-04 2012-06-05 Intellikine, Inc. Substituted isoquinolin-1(2H)-ones, and methods of use thereof
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US20110224223A1 (en) 2008-07-08 2011-09-15 The Regents Of The University Of California, A California Corporation MTOR Modulators and Uses Thereof
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WO2010036380A1 (fr) 2008-09-26 2010-04-01 Intellikine, Inc. Inhibiteurs hétérocycliques de kinases
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EP2751112B1 (fr) 2011-09-02 2019-10-09 The Regents of The University of California Pyrazolo[3,4-d]pyrimidines substituées et utilisations de celles-ci
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Also Published As

Publication number Publication date
IL122335A0 (en) 1998-04-05
CZ392797A3 (cs) 1999-04-14
OA10639A (en) 2002-09-17
SK166097A3 (en) 1999-06-11
EP0832091B1 (fr) 2004-01-14
EA199800009A1 (ru) 1998-06-25
DE69631330D1 (de) 2004-02-19
HUP9802193A2 (hu) 1999-05-28
DE69631330T2 (de) 2004-10-28
PL323904A1 (en) 1998-04-27
EP0832091A1 (fr) 1998-04-01
MX9709859A (es) 1998-08-30
CN1190401A (zh) 1998-08-12
JPH11507387A (ja) 1999-06-29
WO1996040705A1 (fr) 1996-12-19
NO975585L (no) 1998-02-05
US5674998A (en) 1997-10-07
BR9609013A (pt) 1999-12-14
AU6178396A (en) 1996-12-30
KR19990022740A (ko) 1999-03-25
ATE257841T1 (de) 2004-01-15
HUP9802193A3 (en) 1999-10-28
NO975585D0 (no) 1997-12-03
CA2220642A1 (fr) 1996-12-19
AP9701165A0 (en) 1998-01-31
TR199701539T1 (xx) 1998-04-21
IS4621A (is) 1997-11-26

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