BG101602A - Pharmaceutical piperazine compounds - Google Patents
Pharmaceutical piperazine compoundsInfo
- Publication number
- BG101602A BG101602A BG101602A BG10160297A BG101602A BG 101602 A BG101602 A BG 101602A BG 101602 A BG101602 A BG 101602A BG 10160297 A BG10160297 A BG 10160297A BG 101602 A BG101602 A BG 101602A
- Authority
- BG
- Bulgaria
- Prior art keywords
- group
- value
- nco2r11
- c6alkyl
- alkenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9426224.3A GB9426224D0 (en) | 1994-12-23 | 1994-12-23 | Pharmaceutical compounds |
| PCT/GB1995/003027 WO1996020190A1 (en) | 1994-12-23 | 1995-12-22 | Piperazine 2,5 dione derivatives as modulators of multi-drug resistance |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG101602A true BG101602A (en) | 1998-02-27 |
Family
ID=10766589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG101602A BG101602A (en) | 1994-12-23 | 1997-06-11 | Pharmaceutical piperazine compounds |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0799222A1 (cs) |
| JP (1) | JPH10511384A (cs) |
| CN (1) | CN1175253A (cs) |
| AU (1) | AU698828B2 (cs) |
| BG (1) | BG101602A (cs) |
| BR (1) | BR9510410A (cs) |
| CA (1) | CA2207500A1 (cs) |
| CZ (1) | CZ190097A3 (cs) |
| FI (1) | FI972660A7 (cs) |
| GB (1) | GB9426224D0 (cs) |
| HU (1) | HUT77943A (cs) |
| IL (1) | IL116525A0 (cs) |
| NO (1) | NO972937L (cs) |
| NZ (1) | NZ297847A (cs) |
| PL (1) | PL320916A1 (cs) |
| SK (1) | SK83697A3 (cs) |
| TW (1) | TW358094B (cs) |
| WO (1) | WO1996020190A1 (cs) |
| ZA (1) | ZA9510909B (cs) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9717576D0 (en) * | 1997-08-19 | 1997-10-22 | Xenova Ltd | Pharmaceutical compounds |
| ZA979329B (en) * | 1996-10-18 | 1999-04-19 | Xenova Ltd | Pharmaceutical compounds |
| GB9708805D0 (en) | 1997-05-01 | 1997-06-25 | Smithkline Beecham Plc | Compounds |
| GB9810876D0 (en) | 1998-05-20 | 1998-07-22 | Smithkline Beecham Plc | Compounds |
| AP2001002114A0 (en) | 1998-10-08 | 2001-06-30 | Smithkline Beecham Plc | Tetrahydrobenzazepine derivatives useful as modulators of dopamine D3 receptors (antipsychotic agents). |
| BRPI0017067B8 (pt) * | 2000-01-18 | 2021-05-25 | Beyondspring Pharmaceuticals Inc | inibidor de divisão de célula, desidrogenase, método para a produção de um inibidor de divisão de célula e composto |
| CA2453050A1 (en) | 2000-09-06 | 2002-03-14 | A.P. Pharma, Inc. | Degradable polyacetal polymers |
| US6693099B2 (en) | 2000-10-17 | 2004-02-17 | The Procter & Gamble Company | Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance |
| US7935704B2 (en) | 2003-08-01 | 2011-05-03 | Nereus Pharmaceuticals, Inc. | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof |
| ES2295695T3 (es) | 2002-08-02 | 2008-04-16 | Nereus Pharmaceuticals, Inc. | Deshidrofenilahistinas y sus analogos y la sintesis de deshidrofenilahistinas y sus analogos. |
| US7919497B2 (en) | 2002-08-02 | 2011-04-05 | Nereus Pharmaceuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| US8129527B2 (en) | 2006-11-03 | 2012-03-06 | Nereus Pharmacuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| CN103396372B (zh) * | 2013-08-09 | 2015-05-20 | 中国科学院南海海洋研究所 | 一类2,5-二酮哌嗪衍生物及其制备方法和在制备抗海洋污损生物防除剂中的应用 |
| CA2978679A1 (en) | 2015-03-06 | 2016-09-15 | Beyondspring Pharmaceuticals, Inc. | Method of treating a brain tumor |
| SG11201707127VA (en) | 2015-03-06 | 2017-09-28 | Beyondspring Pharmaceuticals Inc | Method of treating cancer associated with a ras mutation |
| SG10202108194XA (en) | 2015-07-13 | 2021-09-29 | Beyondspring Pharmaceuticals Inc | Plinabulin compositions |
| RU2753543C1 (ru) | 2016-02-08 | 2021-08-17 | Бейондспринг Фармасьютикалс, Инк. | Композиции, содержащие тукаресол или его аналоги |
| CN118304304A (zh) | 2016-06-06 | 2024-07-09 | 大连万春布林医药有限公司 | 用于减少中性粒细胞减少症的组合物和方法 |
| EP3565812B1 (en) | 2017-01-06 | 2023-12-27 | Beyondspring Pharmaceuticals, Inc. | Tubulin binding compounds and therapeutic use thereof |
| CN110381938A (zh) | 2017-02-01 | 2019-10-25 | 大连万春布林医药有限公司 | 减少中性粒细胞缺乏症的方法 |
| US11786523B2 (en) | 2018-01-24 | 2023-10-17 | Beyondspring Pharmaceuticals, Inc. | Composition and method for reducing thrombocytopenia |
| US20240197723A1 (en) | 2021-04-09 | 2024-06-20 | Beyondspring Pharmaceuticals, Inc. | Therapeutic compositions and methods for treating tumors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0649410B1 (en) * | 1992-07-10 | 1997-05-02 | Laboratoires Glaxo Sa | Anilide derivatives |
| GB9217331D0 (en) * | 1992-08-14 | 1992-09-30 | Xenova Ltd | Pharmaceutical compounds |
-
1994
- 1994-12-23 GB GBGB9426224.3A patent/GB9426224D0/en active Pending
-
1995
- 1995-12-21 ZA ZA9510909A patent/ZA9510909B/xx unknown
- 1995-12-22 HU HU9800398A patent/HUT77943A/hu unknown
- 1995-12-22 CA CA002207500A patent/CA2207500A1/en not_active Abandoned
- 1995-12-22 CN CN95197672A patent/CN1175253A/zh active Pending
- 1995-12-22 WO PCT/GB1995/003027 patent/WO1996020190A1/en not_active Application Discontinuation
- 1995-12-22 NZ NZ297847A patent/NZ297847A/en unknown
- 1995-12-22 BR BR9510410-0A patent/BR9510410A/pt not_active Application Discontinuation
- 1995-12-22 IL IL11652595A patent/IL116525A0/xx unknown
- 1995-12-22 CZ CZ971900A patent/CZ190097A3/cs unknown
- 1995-12-22 SK SK836-97A patent/SK83697A3/sk unknown
- 1995-12-22 PL PL95320916A patent/PL320916A1/xx unknown
- 1995-12-22 FI FI972660A patent/FI972660A7/fi unknown
- 1995-12-22 AU AU43100/96A patent/AU698828B2/en not_active Ceased
- 1995-12-22 JP JP8520301A patent/JPH10511384A/ja active Pending
- 1995-12-22 EP EP95941797A patent/EP0799222A1/en not_active Withdrawn
- 1995-12-23 TW TW084113836A patent/TW358094B/zh active
-
1997
- 1997-06-11 BG BG101602A patent/BG101602A/xx unknown
- 1997-06-23 NO NO972937A patent/NO972937L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ297847A (en) | 1999-04-29 |
| CA2207500A1 (en) | 1996-07-04 |
| NO972937D0 (no) | 1997-06-23 |
| CZ190097A3 (cs) | 1998-01-14 |
| EP0799222A1 (en) | 1997-10-08 |
| ZA9510909B (en) | 1996-08-30 |
| HUT77943A (hu) | 1998-12-28 |
| BR9510410A (pt) | 1999-09-08 |
| WO1996020190A1 (en) | 1996-07-04 |
| FI972660A0 (fi) | 1997-06-19 |
| JPH10511384A (ja) | 1998-11-04 |
| FI972660L (fi) | 1997-08-22 |
| TW358094B (en) | 1999-05-11 |
| CN1175253A (zh) | 1998-03-04 |
| PL320916A1 (en) | 1997-11-10 |
| AU698828B2 (en) | 1998-11-05 |
| GB9426224D0 (en) | 1995-02-22 |
| NO972937L (no) | 1997-06-23 |
| IL116525A0 (en) | 1996-03-31 |
| FI972660A7 (fi) | 1997-08-22 |
| AU4310096A (en) | 1996-07-19 |
| SK83697A3 (en) | 1998-05-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BG101602A (en) | Pharmaceutical piperazine compounds | |
| BG99496A (bg) | Фармацевтични съединения | |
| BG104248A (en) | Benzamidoxim derivatives, intermediate products and methods for preparing and using them as fungicides | |
| TW370450B (en) | Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives | |
| MXPA94002358A (es) | Compuestos fotocromicos. | |
| CO4970713A1 (es) | Derivados de carboxamidotiazoles, su preparacion, composiciones farmaceuticas que los contienen | |
| BG103663A (en) | 4-(3-heterocyclyl-1-benzoyl)pyrazols and their application as herbicides | |
| EP1496375A3 (en) | Composition for optical film comprising a near-infrared absorbing dye and a quencher | |
| ES467845A1 (es) | Procedimiento para la obtencion de colorantes azoicos | |
| GB2338233A (en) | Red colouring hyperchromic 3 H-Naphtho[2,1-b]Pyrans | |
| AR008296A1 (es) | Compuestos derivados de tetrahidroquinolina, proceso para su preparacion, composiciones que los contienen y su uso en la preparacion de una composicion | |
| TW268046B (cs) | ||
| EP0211272A3 (en) | Azo compound and colored composition containing same | |
| IE802684L (en) | Quinoline derivatives | |
| GB1393263A (en) | Fluorescent dyes | |
| ES455074A1 (es) | Procedimiento para la preparacion de compuestos de 3-indolil-3-bis-aminofenilftalida. | |
| CA2244417A1 (en) | Optically active bisoxazoline compounds, production and use thereof | |
| TW362954B (en) | Stabilized composition, method for using said composition, and medium containing said | |
| ES473455A1 (es) | Procedimiento para la preparacion de benzopiranotiazoles | |
| DE3468104D1 (en) | New aryloxypropanolamine derivatives, process for the preparation thereof, pharmaceutical compositions and therapeutic use | |
| ES458422A1 (es) | Procedimiento para la preparacion de compuestos azometini- cos. | |
| GB1499181A (en) | Dyes for thermoplastics | |
| DE3866411D1 (de) | Ungesaettigte derivate von methylendianilin. | |
| GB1331670A (en) | Quaternised benzofuranylbenzimadzoles | |
| WO2002072540A3 (en) | Improved methods of ortho alkylation |